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Volumn 33, Issue 8, 2015, Pages 1868-1877

Peptide vaccines in breast cancer: The immunological basis for clinical response

Author keywords

Breast cancer; Breast cancer immunotherapy; Breast cancer therapy; Peptide based vaccines; Tumor associated antigens

Indexed keywords

ANTIGENS; EPITOPES; PEPTIDES; PROTEINS; T-CELLS; TUMORS; VACCINES;

EID: 84961885009     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2015.10.013     Document Type: Review
Times cited : (52)

References (85)
  • 1
    • 84903696056 scopus 로고    scopus 로고
    • Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist
    • Abdel-Aal A.B., Lakshminarayanan V., Thompson P., Supekar N., Bradley J.M., Wolfert M.A., et al. Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist. Chembiochem 2014, 15:1508-1513.
    • (2014) Chembiochem , vol.15 , pp. 1508-1513
    • Abdel-Aal, A.B.1    Lakshminarayanan, V.2    Thompson, P.3    Supekar, N.4    Bradley, J.M.5    Wolfert, M.A.6
  • 2
    • 65249154941 scopus 로고    scopus 로고
    • Tumor vaccines for breast cancer
    • Anderson K.S. Tumor vaccines for breast cancer. Cancer Investig. 2009, 27:361-368.
    • (2009) Cancer Investig. , vol.27 , pp. 361-368
    • Anderson, K.S.1
  • 4
    • 84925627711 scopus 로고    scopus 로고
    • Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients
    • Bailur J.K., Gueckel B., Derhovanessian E., Pawelec G. Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients. Breast Cancer Res. 2015, 17:34.
    • (2015) Breast Cancer Res. , vol.17 , pp. 34
    • Bailur, J.K.1    Gueckel, B.2    Derhovanessian, E.3    Pawelec, G.4
  • 5
    • 84867811471 scopus 로고    scopus 로고
    • First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients
    • Berinstein N.L., Karkada M., Morse M.A., Nemunaitis J.J., Chatta G., Kaufman H., et al. First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients. J. Transl. Med. 2012, 10:156.
    • (2012) J. Transl. Med. , vol.10 , pp. 156
    • Berinstein, N.L.1    Karkada, M.2    Morse, M.A.3    Nemunaitis, J.J.4    Chatta, G.5    Kaufman, H.6
  • 7
    • 78650949758 scopus 로고    scopus 로고
    • Improvement of different vaccine delivery systems for cancer therapy
    • Bolhassani A., Safaiyan S., Rafati S. Improvement of different vaccine delivery systems for cancer therapy. Mol. Cancer 2011, 10:3.
    • (2011) Mol. Cancer , vol.10 , pp. 3
    • Bolhassani, A.1    Safaiyan, S.2    Rafati, S.3
  • 8
    • 0347382468 scopus 로고    scopus 로고
    • Mini-review CD4 T cells are required for CD8 T cell memory generation
    • Bourgeois C., Tanchot C. Mini-review CD4 T cells are required for CD8 T cell memory generation. Eur. J. Immunol. 2003, 33:3225-3231.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 3225-3231
    • Bourgeois, C.1    Tanchot, C.2
  • 9
    • 84893464293 scopus 로고    scopus 로고
    • Synthetic multivalent glycopeptide-lipopeptide antitumor vaccines: impact of the cluster effect on the killing of tumor cells
    • Cai H., Sun Z.Y., Chen M.S., Zhao Y.F., Kunz H., Li Y.M. Synthetic multivalent glycopeptide-lipopeptide antitumor vaccines: impact of the cluster effect on the killing of tumor cells. Angew. Chem. Int. Ed. Engl. 2014, 53:1699-1703.
    • (2014) Angew. Chem. Int. Ed. Engl. , vol.53 , pp. 1699-1703
    • Cai, H.1    Sun, Z.Y.2    Chen, M.S.3    Zhao, Y.F.4    Kunz, H.5    Li, Y.M.6
  • 10
    • 75649136936 scopus 로고    scopus 로고
    • Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients: United States military cancer institute clinical trials group study I-04
    • Carmichael M.G., Benavides L.C., Holmes J.P., Gates J.D., Mittendorf E.A., Ponniah S., et al. Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients: United States military cancer institute clinical trials group study I-04. Cancer 2010, 116:292-301.
    • (2010) Cancer , vol.116 , pp. 292-301
    • Carmichael, M.G.1    Benavides, L.C.2    Holmes, J.P.3    Gates, J.D.4    Mittendorf, E.A.5    Ponniah, S.6
  • 11
    • 4143058279 scopus 로고    scopus 로고
    • Class II-associated invariant chain peptide expression on myeloid leukemic blasts predicts poor clinical outcome
    • Chamuleau M.E., Souwer Y., Van Ham S.M., Zevenbergen A., Westers T.M., Berkhof J., et al. Class II-associated invariant chain peptide expression on myeloid leukemic blasts predicts poor clinical outcome. Cancer Res. 2004, 64:5546-5550.
    • (2004) Cancer Res. , vol.64 , pp. 5546-5550
    • Chamuleau, M.E.1    Souwer, Y.2    Van Ham, S.M.3    Zevenbergen, A.4    Westers, T.M.5    Berkhof, J.6
  • 12
    • 0037444166 scopus 로고    scopus 로고
    • Development and preclinical evaluation of a Bacillus Calmette-Guerin-MUC1-based novel breast cancer vaccine
    • Chung M.A., Luo Y., O'Donnell M., Rodriguez C., Heber W., Sharma S., et al. Development and preclinical evaluation of a Bacillus Calmette-Guerin-MUC1-based novel breast cancer vaccine. Cancer Res. 2003, 63:1280-1287.
    • (2003) Cancer Res. , vol.63 , pp. 1280-1287
    • Chung, M.A.1    Luo, Y.2    O'Donnell, M.3    Rodriguez, C.4    Heber, W.5    Sharma, S.6
  • 13
    • 34248550936 scopus 로고    scopus 로고
    • Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy
    • Cloosen S., Arnold J., Thio M., Bos G.M., Kyewski B., Germeraad W.T. Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy. Cancer Res. 2007, 67:3919-3926.
    • (2007) Cancer Res. , vol.67 , pp. 3919-3926
    • Cloosen, S.1    Arnold, J.2    Thio, M.3    Bos, G.M.4    Kyewski, B.5    Germeraad, W.T.6
  • 14
    • 84866907617 scopus 로고    scopus 로고
    • Tumor-associated antigens in breast cancer
    • Criscitiello C. Tumor-associated antigens in breast cancer. Breast Care (Basel) 2012, 7:262-266.
    • (2012) Breast Care (Basel) , vol.7 , pp. 262-266
    • Criscitiello, C.1
  • 15
    • 77953749960 scopus 로고    scopus 로고
    • Generation of effector CD8+ T cells and their conversion to memory T cells
    • Cui W., Kaech S.M. Generation of effector CD8+ T cells and their conversion to memory T cells. Immunol. Rev. 2010, 236:151-166.
    • (2010) Immunol. Rev. , vol.236 , pp. 151-166
    • Cui, W.1    Kaech, S.M.2
  • 19
    • 79959743075 scopus 로고    scopus 로고
    • State of the art in tumor antigen and biomarker discovery
    • Even-Desrumeaux K., Baty D., Chames P. State of the art in tumor antigen and biomarker discovery. Cancers (Basel) 2011, 3:2554-2596.
    • (2011) Cancers (Basel) , vol.3 , pp. 2554-2596
    • Even-Desrumeaux, K.1    Baty, D.2    Chames, P.3
  • 20
    • 0141720783 scopus 로고    scopus 로고
    • Cancer vaccines: between the idea and the reality
    • Finn O.J. Cancer vaccines: between the idea and the reality. Nat. Rev. Immunol. 2003, 3:630-641.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 630-641
    • Finn, O.J.1
  • 21
    • 77958196145 scopus 로고    scopus 로고
    • Circulating regulatory T cells (CD4 + CD25 + FOXP3+) decrease in breast cancer patients after vaccination with a modified MHC class II HER2/neu (AE37) peptide
    • Gates J.D., Clifton G.T., Benavides L.C., Sears A.K., Carmichael M.G., Hueman M.T., et al. Circulating regulatory T cells (CD4 + CD25 + FOXP3+) decrease in breast cancer patients after vaccination with a modified MHC class II HER2/neu (AE37) peptide. Vaccine 2010, 28:7476-7482.
    • (2010) Vaccine , vol.28 , pp. 7476-7482
    • Gates, J.D.1    Clifton, G.T.2    Benavides, L.C.3    Sears, A.K.4    Carmichael, M.G.5    Hueman, M.T.6
  • 22
    • 0034071575 scopus 로고    scopus 로고
    • Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21
    • Gilewski T., Adluri S., Ragupathi G., Zhang S., Yao T.J., Panageas K., et al. Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21. Clin. Cancer Res. 2000, 6:1693-1701.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1693-1701
    • Gilewski, T.1    Adluri, S.2    Ragupathi, G.3    Zhang, S.4    Yao, T.J.5    Panageas, K.6
  • 23
    • 84931432007 scopus 로고    scopus 로고
    • Immunology and breast cancer: toward a new way of understanding breast cancer and developing novel therapeutic strategies
    • Gingras I., Azim H.A., Ignatiadis M., Sotiriou C. Immunology and breast cancer: toward a new way of understanding breast cancer and developing novel therapeutic strategies. Clin. Adv. Hematol. Oncol. 2015, 13:372-382.
    • (2015) Clin. Adv. Hematol. Oncol. , vol.13 , pp. 372-382
    • Gingras, I.1    Azim, H.A.2    Ignatiadis, M.3    Sotiriou, C.4
  • 24
    • 49649090374 scopus 로고    scopus 로고
    • Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma
    • Gulley J.L., Arlen P.M., Tsang K.Y., Yokokawa J., Palena C., Poole D.J., et al. Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma. Clin. Cancer Res. 2008, 14:3060-3069.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3060-3069
    • Gulley, J.L.1    Arlen, P.M.2    Tsang, K.Y.3    Yokokawa, J.4    Palena, C.5    Poole, D.J.6
  • 25
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 26
    • 49149117772 scopus 로고    scopus 로고
    • Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide (AE37) vaccine
    • Holmes J.P., Benavides L.C., Gates J.D., Carmichael M.G., Hueman M.T., Mittendorf E.A., et al. Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide (AE37) vaccine. J. Clin. Oncol. 2008, 26:3426-3433.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 3426-3433
    • Holmes, J.P.1    Benavides, L.C.2    Gates, J.D.3    Carmichael, M.G.4    Hueman, M.T.5    Mittendorf, E.A.6
  • 27
    • 79251503953 scopus 로고    scopus 로고
    • Use of booster inoculations to sustain the clinical effect of an adjuvant breast cancer vaccine: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
    • Holmes J.P., Clifton G.T., Patil R., Benavides L.C., Gates J.D., Stojadinovic A., et al. Use of booster inoculations to sustain the clinical effect of an adjuvant breast cancer vaccine: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer. 2011, 117:463-471.
    • (2011) Cancer. , vol.117 , pp. 463-471
    • Holmes, J.P.1    Clifton, G.T.2    Patil, R.3    Benavides, L.C.4    Gates, J.D.5    Stojadinovic, A.6
  • 28
    • 33748376676 scopus 로고    scopus 로고
    • Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon
    • Imanishi T., Kamigaki T., Nakamura T., Hayashi S., Yasuda T., Kawasaki K., et al. Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon. Kobe J. Med. Sci. 2006, 52:85-95.
    • (2006) Kobe J. Med. Sci. , vol.52 , pp. 85-95
    • Imanishi, T.1    Kamigaki, T.2    Nakamura, T.3    Hayashi, S.4    Yasuda, T.5    Kawasaki, K.6
  • 29
    • 1842372075 scopus 로고    scopus 로고
    • Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma
    • Jager E., Ringhoffer M., Altmannsberger M., Arand M., Karbach J., Jager D., et al. Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma. Int. J. Cancer 1997, 71:142-147.
    • (1997) Int. J. Cancer , vol.71 , pp. 142-147
    • Jager, E.1    Ringhoffer, M.2    Altmannsberger, M.3    Arand, M.4    Karbach, J.5    Jager, D.6
  • 31
    • 70349997971 scopus 로고    scopus 로고
    • A synthetic vaccine consisting of a tumor-associated sialyl-T(N)-MUC1 tandem-repeat glycopeptide and tetanus toxoid: induction of a strong and highly selective immune response
    • Kaiser A., Gaidzik N., Westerlind U., Kowalczyk D., Hobel A., Schmitt E., et al. A synthetic vaccine consisting of a tumor-associated sialyl-T(N)-MUC1 tandem-repeat glycopeptide and tetanus toxoid: induction of a strong and highly selective immune response. Angew. Chem. Int. Ed. Engl. 2009, 48:7551-7555.
    • (2009) Angew. Chem. Int. Ed. Engl. , vol.48 , pp. 7551-7555
    • Kaiser, A.1    Gaidzik, N.2    Westerlind, U.3    Kowalczyk, D.4    Hobel, A.5    Schmitt, E.6
  • 32
    • 77955660585 scopus 로고    scopus 로고
    • A liposome-based platform, VacciMax, and its modified water-free platform DepoVax enhance efficacy of in vivo nucleic acid delivery
    • Karkada M., Weir G.M., Quinton T., Fuentes-Ortega A., Mansour M. A liposome-based platform, VacciMax, and its modified water-free platform DepoVax enhance efficacy of in vivo nucleic acid delivery. Vaccine 2010, 28:6176-6182.
    • (2010) Vaccine , vol.28 , pp. 6176-6182
    • Karkada, M.1    Weir, G.M.2    Quinton, T.3    Fuentes-Ortega, A.4    Mansour, M.5
  • 33
    • 77954888739 scopus 로고    scopus 로고
    • A novel breast/ovarian cancer peptide vaccine platform that promotes specific type-1 but not Treg/Tr1-type responses
    • Karkada M., Weir G.M., Quinton T., Sammatur L., MacDonald L.D., Grant A., et al. A novel breast/ovarian cancer peptide vaccine platform that promotes specific type-1 but not Treg/Tr1-type responses. J. Immunother. 2010, 33:250-261.
    • (2010) J. Immunother. , vol.33 , pp. 250-261
    • Karkada, M.1    Weir, G.M.2    Quinton, T.3    Sammatur, L.4    MacDonald, L.D.5    Grant, A.6
  • 34
    • 84896845396 scopus 로고    scopus 로고
    • Therapeutic vaccines and cancer: focus on DPX-0907
    • Karkada M., Berinstein N.L., Mansour M. Therapeutic vaccines and cancer: focus on DPX-0907. Biologics 2014, 8:27-38.
    • (2014) Biologics , vol.8 , pp. 27-38
    • Karkada, M.1    Berinstein, N.L.2    Mansour, M.3
  • 35
    • 84896899290 scopus 로고    scopus 로고
    • Tumor inhibition by DepoVax-based cancer vaccine is accompanied by reduced regulatory/suppressor cell proliferation and tumor infiltration
    • Karkada M., Quinton T., Blackman R., Mansour M. Tumor inhibition by DepoVax-based cancer vaccine is accompanied by reduced regulatory/suppressor cell proliferation and tumor infiltration. ISRN Oncol. 2013, 2013:753427.
    • (2013) ISRN Oncol. , vol.2013 , pp. 753427
    • Karkada, M.1    Quinton, T.2    Blackman, R.3    Mansour, M.4
  • 36
    • 76049083746 scopus 로고    scopus 로고
    • A degenerate HLA-DR epitope pool of HER-2/neu reveals a novel in vivo immunodominant epitope, HER-2/neu88-102
    • Karyampudi L. A degenerate HLA-DR epitope pool of HER-2/neu reveals a novel in vivo immunodominant epitope, HER-2/neu88-102. Clin. Cancer Res. 2010, 16:825-834.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 825-834
    • Karyampudi, L.1
  • 37
    • 0035879093 scopus 로고    scopus 로고
    • Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity
    • Keogh E., Fikes J., Southwood S., Celis E., Chesnut R., Sette A. Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity. J. Immunol. 2001, 167:787-796.
    • (2001) J. Immunol. , vol.167 , pp. 787-796
    • Keogh, E.1    Fikes, J.2    Southwood, S.3    Celis, E.4    Chesnut, R.5    Sette, A.6
  • 38
    • 8644232489 scopus 로고    scopus 로고
    • Tumor-specific immunity in MUC1.Tg mice induced by immunization with peptide vaccines from the cytoplasmic tail of CD227 (MUC1)
    • Kohlgraf K.G. Tumor-specific immunity in MUC1.Tg mice induced by immunization with peptide vaccines from the cytoplasmic tail of CD227 (MUC1). Cancer Immunol. Immunother. 2004, 53:1068-1084.
    • (2004) Cancer Immunol. Immunother. , vol.53 , pp. 1068-1084
    • Kohlgraf, K.G.1
  • 39
    • 74049106976 scopus 로고    scopus 로고
    • Current developments with peptide-based human tumor vaccines
    • Khazaie K., Bonertz A., Beckhove P. Current developments with peptide-based human tumor vaccines. Curr. Opin. Oncol. 2009, 21:524-530.
    • (2009) Curr. Opin. Oncol. , vol.21 , pp. 524-530
    • Khazaie, K.1    Bonertz, A.2    Beckhove, P.3
  • 40
    • 18844388681 scopus 로고    scopus 로고
    • Recognition of prostate and breast tumor cells by helper T lymphocytes specific for a prostate and breast tumor-associated antigen, TARP
    • Kobayashi H., Nagato T., Oikawa K., Sato K., Kimura S., Aoki N., et al. Recognition of prostate and breast tumor cells by helper T lymphocytes specific for a prostate and breast tumor-associated antigen, TARP. Clin. Cancer Res. 2005, 11:3869-3878.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3869-3878
    • Kobayashi, H.1    Nagato, T.2    Oikawa, K.3    Sato, K.4    Kimura, S.5    Aoki, N.6
  • 42
    • 84940352893 scopus 로고    scopus 로고
    • Immunotherapy and complexity: overcoming barriers to control of advanced cancer
    • Lage A. Immunotherapy and complexity: overcoming barriers to control of advanced cancer. MEDICC Rev. 2014, 16:65-72.
    • (2014) MEDICC Rev. , vol.16 , pp. 65-72
    • Lage, A.1
  • 43
    • 84856000561 scopus 로고    scopus 로고
    • Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine
    • Lakshminarayanan V., Thompson P., Wolfert M.A., Buskas T., Bradley J.M., Pathangey L.B., et al. Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:261-266.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 261-266
    • Lakshminarayanan, V.1    Thompson, P.2    Wolfert, M.A.3    Buskas, T.4    Bradley, J.M.5    Pathangey, L.B.6
  • 44
    • 1642376627 scopus 로고    scopus 로고
    • Multiepitope Trojan antigen peptide vaccines for the induction of antitumor CTL and Th immune responses
    • Lu J., Higashimoto Y., Appella E., Celis E. Multiepitope Trojan antigen peptide vaccines for the induction of antitumor CTL and Th immune responses. J. Immunol. 2004, 172:4575-4582.
    • (2004) J. Immunol. , vol.172 , pp. 4575-4582
    • Lu, J.1    Higashimoto, Y.2    Appella, E.3    Celis, E.4
  • 45
    • 84872177374 scopus 로고    scopus 로고
    • HLA class II molecules influence susceptibility versus protection in inflammatory diseases by determining the cytokine profile
    • Mangalam A.K., Taneja V., David C.S. HLA class II molecules influence susceptibility versus protection in inflammatory diseases by determining the cytokine profile. J. Immunol. 2013, 190:513-518.
    • (2013) J. Immunol. , vol.190 , pp. 513-518
    • Mangalam, A.K.1    Taneja, V.2    David, C.S.3
  • 46
    • 20044364936 scopus 로고    scopus 로고
    • Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas
    • Marshall J.L., Gulley J.L., Arlen P.M., Beetham P.K., Tsang K.Y., Slack R., et al. Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. J. Clin. Oncol. 2005, 23:720-731.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 720-731
    • Marshall, J.L.1    Gulley, J.L.2    Arlen, P.M.3    Beetham, P.K.4    Tsang, K.Y.5    Slack, R.6
  • 47
    • 84861128128 scopus 로고    scopus 로고
    • L-BLP25 vaccine plus letrozole induces a TH1 immune response and has additive antitumor activity in MUC1-expressing mammary tumors in mice
    • Mehta N.R., Wurz G.T., Burich R.A., Greenberg B.E., Griffey S., Gutierrez A., et al. L-BLP25 vaccine plus letrozole induces a TH1 immune response and has additive antitumor activity in MUC1-expressing mammary tumors in mice. Clin. Cancer Res. 2012, 18:2861-2871.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 2861-2871
    • Mehta, N.R.1    Wurz, G.T.2    Burich, R.A.3    Greenberg, B.E.4    Griffey, S.5    Gutierrez, A.6
  • 48
    • 51349123892 scopus 로고    scopus 로고
    • Cancer immunotherapy by dendritic cells
    • Melief C.J. Cancer immunotherapy by dendritic cells. Immunity 2008, 29:372-383.
    • (2008) Immunity , vol.29 , pp. 372-383
    • Melief, C.J.1
  • 49
    • 84860700518 scopus 로고    scopus 로고
    • Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
    • Mittendorf E.A., Clifton G.T., Holmes J.P., Clive K.S., Patil R., Benavides L.C., et al. Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer 2012, 118:2594-2602.
    • (2012) Cancer , vol.118 , pp. 2594-2602
    • Mittendorf, E.A.1    Clifton, G.T.2    Holmes, J.P.3    Clive, K.S.4    Patil, R.5    Benavides, L.C.6
  • 50
    • 84906847366 scopus 로고    scopus 로고
    • Final report of the phase I/II clinical trial of the E75 (nelipepimut-S) vaccine with booster inoculations to prevent disease recurrence in high-risk breast cancer patients
    • Mittendorf E.A., Clifton G.T., Holmes J.P., Schneble E., van Echo D., Ponniah S., et al. Final report of the phase I/II clinical trial of the E75 (nelipepimut-S) vaccine with booster inoculations to prevent disease recurrence in high-risk breast cancer patients. Ann. Oncol. 2014, 25:1735-1742.
    • (2014) Ann. Oncol. , vol.25 , pp. 1735-1742
    • Mittendorf, E.A.1    Clifton, G.T.2    Holmes, J.P.3    Schneble, E.4    van Echo, D.5    Ponniah, S.6
  • 51
    • 84902659459 scopus 로고    scopus 로고
    • Breast cancer immunotherapy: monoclonal antibodies and peptide-based vaccines
    • Mohit E., Hashemi A., Allahyari M. Breast cancer immunotherapy: monoclonal antibodies and peptide-based vaccines. Expert. Rev. Clin. Immunol. 2014, 10:927-961.
    • (2014) Expert. Rev. Clin. Immunol. , vol.10 , pp. 927-961
    • Mohit, E.1    Hashemi, A.2    Allahyari, M.3
  • 52
    • 84870444019 scopus 로고    scopus 로고
    • Depletion of Tregs in vivo: a promising approach to enhance antitumor immunity without autoimmunity
    • Morita R., Hirohashi Y., Sato N. Depletion of Tregs in vivo: a promising approach to enhance antitumor immunity without autoimmunity. Immunotherapy 2012, 4:1103-1105.
    • (2012) Immunotherapy , vol.4 , pp. 1103-1105
    • Morita, R.1    Hirohashi, Y.2    Sato, N.3
  • 53
    • 79956018406 scopus 로고    scopus 로고
    • MHC class I-presented tumor antigens identified in ovarian cancer by immunoproteomic analysis are targets for T-cell responses against breast and ovarian cancer
    • Morse M.A., Secord A.A., Blackwell K., Hobeika A.C., Sinnathamby G., Osada T., et al. MHC class I-presented tumor antigens identified in ovarian cancer by immunoproteomic analysis are targets for T-cell responses against breast and ovarian cancer. Clin. Cancer Res. 2011, 17:3408-3419.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 3408-3419
    • Morse, M.A.1    Secord, A.A.2    Blackwell, K.3    Hobeika, A.C.4    Sinnathamby, G.5    Osada, T.6
  • 55
    • 0032473562 scopus 로고    scopus 로고
    • Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors
    • Ossendorp F., Mengede E., Camps M., Filius R., Melief C.J. Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors. J. Exp. Med. 1998, 187:693-702.
    • (1998) J. Exp. Med. , vol.187 , pp. 693-702
    • Ossendorp, F.1    Mengede, E.2    Camps, M.3    Filius, R.4    Melief, C.J.5
  • 56
    • 0031782910 scopus 로고    scopus 로고
    • The role of CD4+ T cell responses in antitumor immunity
    • Pardoll D.M., Topalian S.L. The role of CD4+ T cell responses in antitumor immunity. Curr. Opin. Immunol. 1998, 10:588-594.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 588-594
    • Pardoll, D.M.1    Topalian, S.L.2
  • 57
    • 74749089482 scopus 로고    scopus 로고
    • Clinical and immunologic responses of HLA-A3+ breast cancer patients vaccinated with the HER2/neu-derived peptide vaccine, E75, in a phase I/II clinical trial
    • Patil R., Clifton G.T., Holmes J.P., Amin A., Carmichael M.G., Gates J.D., et al. Clinical and immunologic responses of HLA-A3+ breast cancer patients vaccinated with the HER2/neu-derived peptide vaccine, E75, in a phase I/II clinical trial. J. Am. Coll. Surg. 2010, 210:140-147.
    • (2010) J. Am. Coll. Surg. , vol.210 , pp. 140-147
    • Patil, R.1    Clifton, G.T.2    Holmes, J.P.3    Amin, A.4    Carmichael, M.G.5    Gates, J.D.6
  • 58
    • 27144464759 scopus 로고    scopus 로고
    • Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients
    • Peoples G.E., Gurney J.M., Hueman M.T., Woll M.M., Ryan G.B., Storrer C.E., et al. Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients. J. Clin. Oncol. 2005, 23:7536-7545.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7536-7545
    • Peoples, G.E.1    Gurney, J.M.2    Hueman, M.T.3    Woll, M.M.4    Ryan, G.B.5    Storrer, C.E.6
  • 59
    • 84888347277 scopus 로고    scopus 로고
    • Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity
    • Perret R., Sierro S.R., Botelho N.K., Corgnac S., Donda A., Romero P. Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity. Cancer Res. 2013, 73:6597-6608.
    • (2013) Cancer Res. , vol.73 , pp. 6597-6608
    • Perret, R.1    Sierro, S.R.2    Botelho, N.K.3    Corgnac, S.4    Donda, A.5    Romero, P.6
  • 61
    • 34247891741 scopus 로고    scopus 로고
    • More than one reason to rethink the use of peptides in vaccine design
    • Purcell A.W., McCluskey J., Rossjohn J. More than one reason to rethink the use of peptides in vaccine design. Nat. Rev. Drug Discov. 2007, 6:404-414.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 404-414
    • Purcell, A.W.1    McCluskey, J.2    Rossjohn, J.3
  • 62
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail D.F., Joyce J.A. Microenvironmental regulation of tumor progression and metastasis. Nat. Med. 2013, 19:1423-1437.
    • (2013) Nat. Med. , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 63
    • 0037606199 scopus 로고    scopus 로고
    • Naturally occurring peptides associated with HLA-A2 in ovarian cancer cell lines identified by mass spectrometry are targets of HLA-A2-restricted cytotoxic T cells
    • Ramakrishna V., Ross M.M., Petersson M., Gatlin C.C., Lyons C.E., Miller C.L., et al. Naturally occurring peptides associated with HLA-A2 in ovarian cancer cell lines identified by mass spectrometry are targets of HLA-A2-restricted cytotoxic T cells. Int. Immunol. 2003, 15:751-763.
    • (2003) Int. Immunol. , vol.15 , pp. 751-763
    • Ramakrishna, V.1    Ross, M.M.2    Petersson, M.3    Gatlin, C.C.4    Lyons, C.E.5    Miller, C.L.6
  • 64
    • 47949124522 scopus 로고    scopus 로고
    • CD4 help regulates expression of crucial genes involved in CD8 T cell memory and sensitivity to regulatory elements
    • Rapetti L., Meunier S., Pontoux C., Tanchot C. CD4 help regulates expression of crucial genes involved in CD8 T cell memory and sensitivity to regulatory elements. J. Immunol. 2008, 181:299-308.
    • (2008) J. Immunol. , vol.181 , pp. 299-308
    • Rapetti, L.1    Meunier, S.2    Pontoux, C.3    Tanchot, C.4
  • 65
    • 84886943278 scopus 로고    scopus 로고
    • Early in vivo signaling profiles in MUC1-specific CD4 T cells responding to two different MUC1-targeting vaccines in two different microenvironments
    • Reichenbach D.K., Finn O.J. Early in vivo signaling profiles in MUC1-specific CD4 T cells responding to two different MUC1-targeting vaccines in two different microenvironments. Oncoimmunology 2013, 2.
    • (2013) Oncoimmunology , vol.2
    • Reichenbach, D.K.1    Finn, O.J.2
  • 67
    • 84859514198 scopus 로고    scopus 로고
    • LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases: a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial
    • Schimanski C.C., Mohler M., Schon M., van Cutsem E., Greil R., Bechstein W.O., et al. LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases: a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial. BMC Cancer 2012, 12:144.
    • (2012) BMC Cancer , vol.12 , pp. 144
    • Schimanski, C.C.1    Mohler, M.2    Schon, M.3    van Cutsem, E.4    Greil, R.5    Bechstein, W.O.6
  • 68
    • 0032866605 scopus 로고    scopus 로고
    • The diversity of T-cell co-stimulation in the induction of antitumor immunity
    • Schlom J., Hodge J.W. The diversity of T-cell co-stimulation in the induction of antitumor immunity. Immunol. Rev. 1999, 170:73-84.
    • (1999) Immunol. Rev. , vol.170 , pp. 73-84
    • Schlom, J.1    Hodge, J.W.2
  • 70
    • 0035893563 scopus 로고    scopus 로고
    • Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway
    • Seliger B., Ritz U., Abele R., Bock M., Tampe R., Sutter G., et al. Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway. Cancer Res. 2001, 61:8647-8650.
    • (2001) Cancer Res. , vol.61 , pp. 8647-8650
    • Seliger, B.1    Ritz, U.2    Abele, R.3    Bock, M.4    Tampe, R.5    Sutter, G.6
  • 71
    • 84885366396 scopus 로고    scopus 로고
    • Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Senkus E., Kyriakides S., Penault-Llorca F., Poortmans P., Thompson A., Zackrisson S., et al. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 2013, 24(Suppl. 6):vi7-v23.
    • (2013) Ann. Oncol. , vol.24 , pp. vi7-v23
    • Senkus, E.1    Kyriakides, S.2    Penault-Llorca, F.3    Poortmans, P.4    Thompson, A.5    Zackrisson, S.6
  • 72
    • 0036218697 scopus 로고    scopus 로고
    • Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules
    • Shastri N., Schwab S., Serwold T. Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules. Annu. Rev. Immunol. 2002, 20:463-493.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 463-493
    • Shastri, N.1    Schwab, S.2    Serwold, T.3
  • 73
    • 33747883766 scopus 로고    scopus 로고
    • Cell surface-associated mucins in signal transduction
    • Singh P.K., Hollingsworth M.A. Cell surface-associated mucins in signal transduction. Trends Cell Biol. 2006, 16:467-476.
    • (2006) Trends Cell Biol. , vol.16 , pp. 467-476
    • Singh, P.K.1    Hollingsworth, M.A.2
  • 74
    • 0036831613 scopus 로고    scopus 로고
    • New aspects of natural-killer-cell surveillance and therapy of cancer
    • Smyth M.J., Hayakawa Y., Takeda K., Yagita H. New aspects of natural-killer-cell surveillance and therapy of cancer. Nat. Rev. Cancer 2002, 2:850-861.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 850-861
    • Smyth, M.J.1    Hayakawa, Y.2    Takeda, K.3    Yagita, H.4
  • 75
    • 0035339389 scopus 로고    scopus 로고
    • Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection
    • Soares M.M., Mehta V., Finn O.J. Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection. J. Immunol. 2001, 166:6555-6563.
    • (2001) J. Immunol. , vol.166 , pp. 6555-6563
    • Soares, M.M.1    Mehta, V.2    Finn, O.J.3
  • 76
    • 0034650421 scopus 로고    scopus 로고
    • Cutting edge: CD4+ T cell control of CD8+ T cell reactivity to a model tumor antigen
    • Surman D.R., Dudley M.E., Overwijk W.W., Restifo N.P. Cutting edge: CD4+ T cell control of CD8+ T cell reactivity to a model tumor antigen. J. Immunol. 2000, 164:562-565.
    • (2000) J. Immunol. , vol.164 , pp. 562-565
    • Surman, D.R.1    Dudley, M.E.2    Overwijk, W.W.3    Restifo, N.P.4
  • 77
    • 84905405261 scopus 로고    scopus 로고
    • Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients
    • Takahashi R., Toh U., Iwakuma N., Takenaka M., Otsuka H., Furukawa M., et al. Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients. Breast Cancer Res. 2014, 16:R70.
    • (2014) Breast Cancer Res. , vol.16 , pp. R70
    • Takahashi, R.1    Toh, U.2    Iwakuma, N.3    Takenaka, M.4    Otsuka, H.5    Furukawa, M.6
  • 78
    • 84885390747 scopus 로고    scopus 로고
    • Cancer treatment using peptides: current therapies and future prospects
    • Thundimadathil J. Cancer treatment using peptides: current therapies and future prospects. J. Amino Acids 2012, 2012:967347.
    • (2012) J. Amino Acids , vol.2012 , pp. 967347
    • Thundimadathil, J.1
  • 79
    • 79953293521 scopus 로고    scopus 로고
    • Absence of class II-associated invariant chain peptide on leukemic blasts of patients promotes activation of autologous leukemia-reactive CD4+ T cells
    • van Luijn M.M., van den Ancker W., Chamuleau M.E., Zevenbergen A., Westers T.M., Ossenkoppele G.J., et al. Absence of class II-associated invariant chain peptide on leukemic blasts of patients promotes activation of autologous leukemia-reactive CD4+ T cells. Cancer Res. 2011, 71:2507-2517.
    • (2011) Cancer Res. , vol.71 , pp. 2507-2517
    • van Luijn, M.M.1    van den Ancker, W.2    Chamuleau, M.E.3    Zevenbergen, A.4    Westers, T.M.5    Ossenkoppele, G.J.6
  • 80
    • 84887222277 scopus 로고    scopus 로고
    • Up to 15-year clinical follow-up of a pilot phase III immunotherapy study in stage II breast cancer patients using oxidized mannan-MUC1
    • Vassilaros S., Tsibanis A., Tsikkinis A., Pietersz G.A., McKenzie I.F., Apostolopoulos V. Up to 15-year clinical follow-up of a pilot phase III immunotherapy study in stage II breast cancer patients using oxidized mannan-MUC1. Immunotherapy 2013, 5:1177-1182.
    • (2013) Immunotherapy , vol.5 , pp. 1177-1182
    • Vassilaros, S.1    Tsibanis, A.2    Tsikkinis, A.3    Pietersz, G.A.4    McKenzie, I.F.5    Apostolopoulos, V.6
  • 81
    • 10044265684 scopus 로고    scopus 로고
    • Glycoprotein tumor antigens for immunotherapy of breast cancer
    • Vlad A.M., Finn O.J. Glycoprotein tumor antigens for immunotherapy of breast cancer. Breast Dis. 2004, 20:73-79.
    • (2004) Breast Dis. , vol.20 , pp. 73-79
    • Vlad, A.M.1    Finn, O.J.2
  • 83
    • 80053479472 scopus 로고    scopus 로고
    • INSPIRE: a phase III study of the BLP25 liposome vaccine (L-BLP25) in Asian patients with unresectable stage III non-small cell lung cancer
    • Wu Y.L., Park K., Soo R.A., Sun Y., Tyroller K., Wages D., et al. INSPIRE: a phase III study of the BLP25 liposome vaccine (L-BLP25) in Asian patients with unresectable stage III non-small cell lung cancer. BMC Cancer 2011, 11:430.
    • (2011) BMC Cancer , vol.11 , pp. 430
    • Wu, Y.L.1    Park, K.2    Soo, R.A.3    Sun, Y.4    Tyroller, K.5    Wages, D.6
  • 84
    • 4344582378 scopus 로고    scopus 로고
    • Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance
    • Yu Z., Theoret M.R., Touloukian C.E., Surman D.R., Garman S.C., Feigenbaum L., et al. Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance. J. Clin. Invest. 2004, 114:551-559.
    • (2004) J. Clin. Invest. , vol.114 , pp. 551-559
    • Yu, Z.1    Theoret, M.R.2    Touloukian, C.E.3    Surman, D.R.4    Garman, S.C.5    Feigenbaum, L.6
  • 85
    • 84904311913 scopus 로고    scopus 로고
    • Loss of expression of MHC class I-related chain A (MICA) is a frequent event and predicts poor survival in patients with hepatocellular carcinoma
    • Zhang J., Xu Z., Zhou X., Zhang H., Yang N., Wu Y., et al. Loss of expression of MHC class I-related chain A (MICA) is a frequent event and predicts poor survival in patients with hepatocellular carcinoma. Int. J. Clin. Exp. Pathol. 2014, 7:3123-3131.
    • (2014) Int. J. Clin. Exp. Pathol. , vol.7 , pp. 3123-3131
    • Zhang, J.1    Xu, Z.2    Zhou, X.3    Zhang, H.4    Yang, N.5    Wu, Y.6


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