메뉴 건너뛰기




Volumn 11, Issue 3, 2010, Pages 146-161

Breast cancer in the personal genomics era

Author keywords

Breast cancer; Gene expression; Genetic tests; Personal genomics; Risk assessment

Indexed keywords

ANTHRACYCLINE; AROMATASE INHIBITOR; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; TAMOXIFEN; TRASTUZUMAB;

EID: 77952507615     PISSN: 13892029     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920210791110951     Document Type: Article
Times cited : (72)

References (150)
  • 3
    • 59449106860 scopus 로고    scopus 로고
    • National Cancer Institute, National Institutes of Health, Department of Health and Human Services: Bethesda, MD
    • Cancer Trends Progress Report - 2007 Update. National Cancer Institute, National Institutes of Health, Department of Health and Human Services: Bethesda, MD, 2007, http://progressreport.cancer.gov.
    • (2007) Cancer Trends Progress Report - 2007 Update
  • 4
    • 0037123341 scopus 로고    scopus 로고
    • Enogenous Hormones and Breast Cancer Collaborative Group. Endogenous sex hormones and breast cancer in postmenopausal women: Reanalysis of nine prospective studies
    • Key, T.; Appleby, P.; Barnes, I.; Reeves, G.; Enogenous Hormones and Breast Cancer Collaborative Group. Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. J. Natl. Cancer Inst., 2002, 94, 606-616.
    • (2002) J. Natl. Cancer Inst , vol.94 , pp. 606-616
    • Key, T.1    Appleby, P.2    Barnes, I.3    Reeves, G.4
  • 7
    • 44449119872 scopus 로고    scopus 로고
    • Trends in breast cancer screening and diagnosis
    • Rim, A.; Chellman-Jeffers, M. Trends in breast cancer screening and diagnosis. Cleve. Clin. J. Med., 2008, 75, S2-S9.
    • (2008) Cleve. Clin. J. Med , vol.75
    • Rim, A.1    Chellman-Jeffers, M.2
  • 8
    • 42749097958 scopus 로고    scopus 로고
    • Nutrition and breast cancer among sporadic cases and gene mutation carriers: An overview
    • Bissonauth, V.; Shatenstein, B.; Ghadirian, P. Nutrition and breast cancer among sporadic cases and gene mutation carriers: An overview. Cancer Detect. Prev., 2008, 32, 52-64.
    • (2008) Cancer Detect. Prev , vol.32 , pp. 52-64
    • Bissonauth, V.1    Shatenstein, B.2    Ghadirian, P.3
  • 11
    • 33947404394 scopus 로고    scopus 로고
    • Improvement of best practice in early breast cancer: Actionable surgeon and hospital factors
    • Gort, M.; Broekhuis, M.; Otter, R.; Klazinga, N.S. Improvement of best practice in early breast cancer: actionable surgeon and hospital factors. Breast Cancer Res. Treat., 2007, 102, 219-226.
    • (2007) Breast Cancer Res. Treat , vol.102 , pp. 219-226
    • Gort, M.1    Broekhuis, M.2    Otter, R.3    Klazinga, N.S.4
  • 13
    • 33646285209 scopus 로고
    • Introduction to Cancer Genetics
    • Charles C. Thomas: Springfield, IL
    • Lynch, H.T. Introduction to Cancer Genetics. In Cancer Genetics, Charles C. Thomas: Springfield, IL, 1976; pp. 3-31.
    • (1976) Cancer Genetics , pp. 3-31
    • Lynch, H.T.1
  • 14
    • 0018853674 scopus 로고
    • Etiologic factors of breast cancer elucidated by a study of unselected twins
    • Holm, N.V.; Hauge, M.; Harvald, B. Etiologic factors of breast cancer elucidated by a study of unselected twins. J. Natl. Cancer Inst., 1980, 65, 285-298.
    • (1980) J. Natl. Cancer Inst , vol.65 , pp. 285-298
    • Holm, N.V.1    Hauge, M.2    Harvald, B.3
  • 15
    • 0021636648 scopus 로고
    • Genetic epidemiology of breast cancer: Segregation analysis of 200 Danish pedigrees
    • Williams, W.R.; Anderson, D.E. Genetic epidemiology of breast cancer: segregation analysis of 200 Danish pedigrees. Genet. Epidemiol., 1984, 1, 7-20.
    • (1984) Genet. Epidemiol , vol.1 , pp. 7-20
    • Williams, W.R.1    Anderson, D.E.2
  • 16
    • 2742525287 scopus 로고
    • Inheritance of human breast cancer: Evidence for autosomal dominant transmission in high-risk families
    • Newman, B.; Austin, M.A.; Lee, M.; King, M.-C. Inheritance of human breast cancer: Evidence for autosomal dominant transmission in high-risk families. Proc. Natl. Acad. Sci. USA, 1988, 85, 3044-3048.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 3044-3048
    • Newman, B.1    Austin, M.A.2    Lee, M.3    King, M.-C.4
  • 23
    • 24644490720 scopus 로고    scopus 로고
    • U.S. Preventive Services Task Force. Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: Systematic evidence review for the U.S. Preventive Services Task Force
    • Nelson, H.D.; Huffman, L.H.; Fu, R.; Harris, E.L. U.S. Preventive Services Task Force. Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for the U.S. Preventive Services Task Force. Ann. Intern. Med., 2005, 143, 362-379.
    • (2005) Ann. Intern. Med , vol.143 , pp. 362-379
    • Nelson, H.D.1    Huffman, L.H.2    Fu, R.3    Harris, E.L.4
  • 25
    • 33749037721 scopus 로고    scopus 로고
    • Clinical management of BRCA1 and BRCA2 mutation carriers
    • Domchek, S.M.; Weber, B.L. Clinical management of BRCA1 and BRCA2 mutation carriers. Oncogene, 2006, 25, 5825-5831.
    • (2006) Oncogene , vol.25 , pp. 5825-5831
    • Domchek, S.M.1    Weber, B.L.2
  • 26
    • 0034597916 scopus 로고    scopus 로고
    • Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: A case-control study. Hereditary Breast Cancer Clinical Study Group
    • Hereditary Breast Cancer Clinical Study Group
    • Narod, S.A.; Brunet, J.-S.; Ghadirian, P.; Robson, M.; Heimdal, K.; Neuhausen, S.L.; Stoppa-Lyonnet, D.; Lerman, C.; Pasini, B.; de los Rios, P.; Weber, B.; Lynch, H. Hereditary Breast Cancer Clinical Study Group. Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study. Hereditary Breast Cancer Clinical Study Group. Lancet, 2000, 356, 1876-1881.
    • (2000) Lancet , vol.356 , pp. 1876-1881
    • Narod, S.A.1    Brunet, J.-S.2    Ghadirian, P.3    Robson, M.4    Heimdal, K.5    Neuhausen, S.L.6    Stoppa-Lyonnet, D.7    Lerman, C.8    Pasini, B.9    de los Rios, P.10    Weber, B.11    Lynch, H.12
  • 28
    • 55849093873 scopus 로고    scopus 로고
    • The Consensus Conference Committee. Proceedings of the International Consensus Conference on Breast Cancer Risk, Genetics, and Risk Management, April, 2007
    • Schwartz, G.F.; Hughes, K.S.; Lynch, H.T.; Fabian, C.J.; Fentiman, I.S.; Robson, M.E.; Domchek, S.M.; Hartmann, L.C.; Holland, R.; Winchester, D.J. The Consensus Conference Committee. Proceedings of the International Consensus Conference on Breast Cancer Risk, Genetics, and Risk Management, April, 2007. Cancer, 2008, 113, 2627-2637.
    • (2008) Cancer , vol.113 , pp. 2627-2637
    • Schwartz, G.F.1    Hughes, K.S.2    Lynch, H.T.3    Fabian, C.J.4    Fentiman, I.S.5    Robson, M.E.6    Domchek, S.M.7    Hartmann, L.C.8    Holland, R.9    Winchester, D.J.10
  • 29
    • 33749022506 scopus 로고    scopus 로고
    • Basal-like breast cancer and the BRCA1 phenotype
    • Turner, N.C.; Reis-Filho, J.S. Basal-like breast cancer and the BRCA1 phenotype. Oncogene, 2006, 25, 5846-5853.
    • (2006) Oncogene , vol.25 , pp. 5846-5853
    • Turner, N.C.1    Reis-Filho, J.S.2
  • 32
    • 33846306403 scopus 로고    scopus 로고
    • Management of BRCA1/2 associated breast cancer: A systematic qualitative review of the state of knowledge in 2006
    • Liebens, F.P.; Carly, B.; Pastijn, A.; Rozenberg, S. Management of BRCA1/2 associated breast cancer: A systematic qualitative review of the state of knowledge in 2006. Eur. J. Cancer, 2007, 43, 238-257.
    • (2007) Eur. J. Cancer , vol.43 , pp. 238-257
    • Liebens, F.P.1    Carly, B.2    Pastijn, A.3    Rozenberg, S.4
  • 37
    • 56949100951 scopus 로고    scopus 로고
    • Can genetic testing guide treatment in breast cancer?
    • Tutt, A.; Ashworth, A. Can genetic testing guide treatment in breast cancer? Eur. J. Cancer, 2008, 44, 2774-2780.
    • (2008) Eur. J. Cancer , vol.44 , pp. 2774-2780
    • Tutt, A.1    Ashworth, A.2
  • 38
    • 0035125062 scopus 로고    scopus 로고
    • Breast Cancer Linkage Consortium. Variation in cancer risks, by mutation position, in BRCA2 mutation carriers
    • Thompson, D.; Easton, D. Breast Cancer Linkage Consortium. Variation in cancer risks, by mutation position, in BRCA2 mutation carriers. Am. J. Hum. Genet., 2001, 68, 410-419.
    • (2001) Am. J. Hum. Genet , vol.68 , pp. 410-419
    • Thompson, D.1    Easton, D.2
  • 39
    • 0036123926 scopus 로고    scopus 로고
    • Breast Cancer Linkage Consortium. Variation in BRCA1 cancer risks by mutation position
    • Thompson, D.; Easton, D. Breast Cancer Linkage Consortium. Variation in BRCA1 cancer risks by mutation position. Cancer Epidemiol. Biomarkers Prev., 2002, 11, 329-336.
    • (2002) Cancer Epidemiol. Biomarkers Prev , vol.11 , pp. 329-336
    • Thompson, D.1    Easton, D.2
  • 40
    • 0028843102 scopus 로고
    • Breast Cancer Linkage Consortium. Breast and ovarian cancer incidence in BRCA1 mutation carriers
    • Easton, D.F.; Ford, D.; Biship, D.T. Breast Cancer Linkage Consortium. Breast and ovarian cancer incidence in BRCA1 mutation carriers. Am. J. Hum. Genet., 1995, 56, 265-271.
    • (1995) Am. J. Hum. Genet , vol.56 , pp. 265-271
    • Easton, D.F.1    Ford, D.2    Biship, D.T.3
  • 41
    • 61649117572 scopus 로고    scopus 로고
    • Environmental chemicals and breast cancer risk-a structural chemistry perspective
    • Weyandt, J.; Ellsworth, R.E.; Hooke, J.A.; Shriver, C.D.; Ellsworth, D.L. Environmental chemicals and breast cancer risk-a structural chemistry perspective. Curr. Med. Chem., 2008, 15, 2680-2701.
    • (2008) Curr. Med. Chem , vol.15 , pp. 2680-2701
    • Weyandt, J.1    Ellsworth, R.E.2    Hooke, J.A.3    Shriver, C.D.4    Ellsworth, D.L.5
  • 42
    • 0142178215 scopus 로고    scopus 로고
    • New York Breast Cancer Study Group. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
    • King, M.-C.; Marks, J.H.; Mandell, J.B. New York Breast Cancer Study Group. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science, 2003, 302, 643-646.
    • (2003) Science , vol.302 , pp. 643-646
    • King, M.-C.1    Marks, J.H.2    Mandell, J.B.3
  • 43
    • 36749002743 scopus 로고    scopus 로고
    • C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies
    • Note
    • Antoniou, A.C.; Sinilnikova, O.M.; Simard, J.; Léoné, M.; Dumont, M.; Neuhausen, S.L.; Struewing, J.P.; Stoppa-Lyonnet, D.; Barjhoux, L.; Hughes, D.J.; Coupier, I.; Belotti, M.; Lasset, C.; Bonadona, V.; Bignon, Y.-J.; Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers Study (GEMO); Rebbeck, T.R.; Wagner, T.; Lynch, H.T.; Domchek, S.M.; Nathanson, K.L.; Garber, J.E.; Weitzel, J.; Narod, S.A.; Tomlinson, G.; Olopade, O.I.; Godwin, A.; Isaacs, C.; Jakubowska, A.; Lubinski, J.; Gronwald, J.; Górski, B.; Byrski, T.; Huzarski, T.; Peock, S.; Cook, M.; Baynes, C.; Murray, A.; Rogers, M.; Daly, P.A.; Dorkins, H.; Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE); Schmutzler, R.K.; Versmold, B.; Engel, C.; Meindl, A.; Arnold, N.; Neideracher, D.; Deissler, H.; German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC); Spurdle, A.B.; Chen, X.; Waddell, N.; Cloonan, N.; The Kathleen Cuningham Consortium for Research into Familial Breast Cancer (kConFab); Kirschoff, T.; Offit, K.; Friedman, E.; Kaufmann, B.; Laitman, Y.; Galore, G.; Rennert, G.; Lejbkowicz, F.; Raskin, L.; Andrulis, I.L.; Ilyushik, E.; Ozcelik, H.; Devilee, P.; Vreeswijk, M.P.G.; Greene, M.H.; Prindiville, S.A.; Osorio, A.; Benítez, J.; Zikan, M.; Szabo, C.I.; Kilpivaara, O.; Nevanlinna, H.; Hamann, U.; Durocher, F.; Arason, A.; Couch, F.J.; Easton, D.F.; Chenevix-Trench, G. Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). RAD51 135G-> C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Am. J. Hum. Genet., 2007, 81, 1186-1200.
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 1186-1200
    • Antoniou, A.C.1    Sinilnikova, O.M.2    Simard, J.3    Léoné, M.4    Dumont, M.5    Neuhausen, S.L.6    Struewing, J.P.7    Stoppa-Lyonnet, D.8    Barjhoux, L.9    Hughes, D.J.10    Coupier, I.11    Belotti, M.12    Lasset, C.13    Bonadona, V.14    Bignon, Y.-J.15
  • 44
    • 48349120930 scopus 로고    scopus 로고
    • Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers
    • Hughes, D.J. Use of association studies to define genetic modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Fam. Cancer, 2008, 7, 233-244.
    • (2008) Fam. Cancer , vol.7 , pp. 233-244
    • Hughes, D.J.1
  • 45
    • 34250164598 scopus 로고    scopus 로고
    • CIMBA. An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: The Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)
    • Chenevix-Trench, G.; Milne, R.L.; Antoniou, A.C.; Couch, F.J.; Easton, D.F.; Goldgar, D.E. CIMBA. An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA). Breast Cancer Res., 2007, 9, 104.
    • (2007) Breast Cancer Res , vol.9 , pp. 104
    • Chenevix-Trench, G.1    Milne, R.L.2    Antoniou, A.C.3    Couch, F.J.4    Easton, D.F.5    Goldgar, D.E.6
  • 47
    • 0035057860 scopus 로고    scopus 로고
    • Other breast cancer susceptibility genes: Searching for more holy grail
    • Nathanson, K.L.; Weber, B.L. Other breast cancer susceptibility genes: searching for more holy grail. Hum. Mol. Genet., 2001, 10, 715-720.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 715-720
    • Nathanson, K.L.1    Weber, B.L.2
  • 48
    • 18444382348 scopus 로고    scopus 로고
    • BreastMed Consortium. The portrait of hereditary breast cancer
    • Lacroix, M.; Leclercq, G. BreastMed Consortium. The portrait of hereditary breast cancer. Breast Cancer Res. Treat., 2005, 89, 297-304.
    • (2005) Breast Cancer Res. Treat , vol.89 , pp. 297-304
    • Lacroix, M.1    Leclercq, G.2
  • 49
    • 0024801278 scopus 로고
    • Projecting individualized probabilities of developing breast cancer for white females who are being examined annually
    • Gail, M.H.; Brinton, L.A.; Byar, D.P.; Corle, D.K.; Green, S.B.; Schairer, C.; Mulvihill, J.J. Projecting individualized probabilities of developing breast cancer for white females who are being examined annually. J. Natl. Cancer Inst., 1989, 81, 1879-1886.
    • (1989) J. Natl. Cancer Inst , vol.81 , pp. 1879-1886
    • Gail, M.H.1    Brinton, L.A.2    Byar, D.P.3    Corle, D.K.4    Green, S.B.5    Schairer, C.6    Mulvihill, J.J.7
  • 50
    • 0027979310 scopus 로고
    • Autosomal dominant inheritance of early-onset breast cancer. Implications for risk prediction
    • Claus, E.B.; Risch, N.; Thompson, W.D. Autosomal dominant inheritance of early-onset breast cancer. Implications for risk prediction. Cancer, 1994, 73, 643-651.
    • (1994) Cancer , vol.73 , pp. 643-651
    • Claus, E.B.1    Risch, N.2    Thompson, W.D.3
  • 51
    • 0031029633 scopus 로고    scopus 로고
    • Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history
    • Berry, D.A.; Parmigiani, G.; Sanchez, J.; Schildkraut, J.; Winer, E. Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history. J. Natl. Cancer Inst., 1997, 89, 227-237.
    • (1997) J. Natl. Cancer Inst , vol.89 , pp. 227-237
    • Berry, D.A.1    Parmigiani, G.2    Sanchez, J.3    Schildkraut, J.4    Winer, E.5
  • 52
    • 0034788375 scopus 로고    scopus 로고
    • Understanding mathematical models for breast cancer risk assessment and counseling
    • Euhus, D.M. Understanding mathematical models for breast cancer risk assessment and counseling. Breast J., 2001, 7, 224-232.
    • (2001) Breast J , vol.7 , pp. 224-232
    • Euhus, D.M.1
  • 53
    • 67349122732 scopus 로고    scopus 로고
    • Differences and similarities in breast cancer risk assessment models in clinical practice: Which model to choose? Breast Cancer Res
    • Jacobi, C.E.; de Bock, G.H.; Siergerink, B.; van Asperen, C.J. Differences and similarities in breast cancer risk assessment models in clinical practice: which model to choose? Breast Cancer Res. Treat., 2009, 115, 381-390.
    • (2009) Treat , vol.115 , pp. 381-390
    • Jacobi, C.E.1    de Bock, G.H.2    Siergerink, B.3    van Asperen, C.J.4
  • 54
    • 1842680082 scopus 로고    scopus 로고
    • A breast cancer prediction model incorporating familial and personal risk factors
    • Tyrer, J.; Duffy, S.W.; Cuzick, J. A breast cancer prediction model incorporating familial and personal risk factors. Stat. Med., 2004, 23, 1111-1130.
    • (2004) Stat. Med , vol.23 , pp. 1111-1130
    • Tyrer, J.1    Duffy, S.W.2    Cuzick, J.3
  • 55
    • 40449138003 scopus 로고    scopus 로고
    • Breast cancer risk-assessment models
    • Evans, D.G.R.; Howell, A. Breast cancer risk-assessment models. Breast Cancer Res., 2007, 9, 213.
    • (2007) Breast Cancer Res , vol.9 , pp. 213
    • Evans, D.G.R.1    Howell, A.2
  • 58
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn, J.N.; Daly, M.J. Genome-wide association studies for common diseases and complex traits. Nat. Rev. Genet., 2005, 6, 95-108.
    • (2005) Nat. Rev. Genet , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 59
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer, K.A.; Murray, S.S.; Schork, N.J.; Topol, E.J. Human genetic variation and its contribution to complex traits. Nat. Rev. Genet., 2009, 10, 241-251.
    • (2009) Nat. Rev. Genet , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 67
    • 45949085378 scopus 로고    scopus 로고
    • Polygenes, risk prediction, and targeted prevention of breast cancer
    • Pharoah, P.D.P.; Antoniou, A.C.; Easton, D.F.; Ponder, B.A.J. Polygenes, risk prediction, and targeted prevention of breast cancer. N. Engl. J. Med., 2008, 358, 2796-2803.
    • (2008) N. Engl. J. Med , vol.358 , pp. 2796-2803
    • Pharoah, P.D.P.1    Antoniou, A.C.2    Easton, D.F.3    Ponder, B.A.J.4
  • 68
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer, W.; Bonilla, C. Common and rare variants in multifactorial susceptibility to common diseases. Nat. Genet., 2008, 40, 695-701.
    • (2008) Nat. Genet , vol.40 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 69
    • 40349084039 scopus 로고    scopus 로고
    • The promise and limitations of genome-wide association studies to elucidate the causes of breast cancer
    • Ambrosone, C.B. The promise and limitations of genome-wide association studies to elucidate the causes of breast cancer. Breast Cancer Res., 2007, 9, 114.
    • (2007) Breast Cancer Res , vol.9 , pp. 114
    • Ambrosone, C.B.1
  • 70
    • 58149359606 scopus 로고    scopus 로고
    • Advances in breast cancer: Pathways to personalized medicine
    • Olopade, O.I.; Grushko, T.A.; Nanda, R.; Huo, D. Advances in breast cancer: Pathways to personalized medicine. Clin. Cancer Res., 2008, 14, 7988-7999.
    • (2008) Clin. Cancer Res , vol.14 , pp. 7988-7999
    • Olopade, O.I.1    Grushko, T.A.2    Nanda, R.3    Huo, D.4
  • 71
    • 58149327181 scopus 로고    scopus 로고
    • The regulation of direct-to-consumer genetic tests
    • Kaye, J. The regulation of direct-to-consumer genetic tests. Hum. Mol. Genet., 2008, 17, R180-R183.
    • (2008) Hum. Mol. Genet , vol.17
    • Kaye, J.1
  • 72
    • 42549161987 scopus 로고    scopus 로고
    • Knowing me, knowing you
    • Lenzer, J.; Brownlee, S. Knowing me, knowing you. BMJ, 2008, 336, 858-860.
    • (2008) BMJ , vol.336 , pp. 858-860
    • Lenzer, J.1    Brownlee, S.2
  • 73
    • 41449113701 scopus 로고    scopus 로고
    • Evaluating online direct-to-consumer marketing of genetic tests: Informed choices or buyers beware?
    • Geransar, R.; Einsiedel, E. Evaluating online direct-to-consumer marketing of genetic tests: informed choices or buyers beware? Genet. Test., 2008, 12, 13-23.
    • (2008) Genet. Test , vol.12 , pp. 13-23
    • Geransar, R.1    Einsiedel, E.2
  • 74
    • 52949089274 scopus 로고    scopus 로고
    • The current landscape for direct-to-consumer genetic testing: Legal, ethical, and policy issues
    • Hogarth, S.; Javitt, G.; Melzer, D. The current landscape for direct-to-consumer genetic testing: Legal, ethical, and policy issues. Annu. Rev. Genomics Hum. Genet., 2008, 9, 161-182.
    • (2008) Annu. Rev. Genomics Hum. Genet , vol.9 , pp. 161-182
    • Hogarth, S.1    Javitt, G.2    Melzer, D.3
  • 76
    • 0030030644 scopus 로고    scopus 로고
    • Infiltrating lobular carcinoma of the breast. Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns
    • Sastre-Garau, X.; Jouve, M.; Asselain, B.; Vincent-Salomon, A.; Beuzeboc, P.; Dorval, T.; Durand, J.-C.; Fourquet, A.; Pouillart, P. Infiltrating lobular carcinoma of the breast. Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns. Cancer, 1996, 77, 113-120.
    • (1996) Cancer , vol.77 , pp. 113-120
    • Sastre-Garau, X.1    Jouve, M.2    Asselain, B.3    Vincent-Salomon, A.4    Beuzeboc, P.5    Dorval, T.6    Durand, J.-C.7    Fourquet, A.8    Pouillart, P.9
  • 78
    • 0034469922 scopus 로고    scopus 로고
    • Molecular biology of breast cancer metastasis. Inflammatory breast cancer: Clinical syndrome and molecular determinants
    • Kleer, C.G.; van Golen, K.L.; Merajver, S.D. Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants. Breast Cancer Res., 2000, 2, 423-429.
    • (2000) Breast Cancer Res , vol.2 , pp. 423-429
    • Kleer, C.G.1    van Golen, K.L.2    Merajver, S.D.3
  • 80
    • 77952495775 scopus 로고    scopus 로고
    • Prognostic and Predictive Factors Overview
    • In, Ross, J.S.; Hortobagyi, G.N., Eds.; Jones and Bartlett Publishers: Sudbury, MA
    • Ross, J.S.; Harbeck, N. Prognostic and Predictive Factors Overview. In Molecular Oncology of Breast Cancer, Ross, J.S.; Hortobagyi, G.N., Eds.; Jones and Bartlett Publishers: Sudbury, MA, 2005, pp. 128-141.
    • (2005) Molecular Oncology of Breast Cancer , pp. 128-141
    • Ross, J.S.1    Harbeck, N.2
  • 81
    • 17744407628 scopus 로고    scopus 로고
    • Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: Influence of margin status and systemic therapy on local recurrence
    • Park, C.C.; Mitsumori, M.; Nixon, A.; Recht, A.; Connolly, J.; Gelman, R.; Silver, B.; Hetelekidis, S.; Abner, A.; Harris, J.R.; Schnitt, S.J. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J. Clin. Onol., 2000, 18, 1668-1675.
    • (2000) J. Clin. Onol , vol.18 , pp. 1668-1675
    • Park, C.C.1    Mitsumori, M.2    Nixon, A.3    Recht, A.4    Connolly, J.5    Gelman, R.6    Silver, B.7    Hetelekidis, S.8    Abner, A.9    Harris, J.R.10    Schnitt, S.J.11
  • 82
    • 33644911778 scopus 로고    scopus 로고
    • Breast conservation surgery achieving >2 mm tumor-free margins results in decreased local-regional recurrence rates
    • Kunos, C.; Latson, L.; Overmoyer, B.; Silverman, P.; Shenk, R.; Kinsella, T.; Lyons, J. Breast conservation surgery achieving >2 mm tumor-free margins results in decreased local-regional recurrence rates. Breast J., 2006, 12, 28-36.
    • (2006) Breast J , vol.12 , pp. 28-36
    • Kunos, C.1    Latson, L.2    Overmoyer, B.3    Silverman, P.4    Shenk, R.5    Kinsella, T.6    Lyons, J.7
  • 83
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • Elston, C.W.; Ellis, I.O. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology, 1991, 19, 403-410.
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 84
    • 0026075244 scopus 로고
    • Relationship among outcome, stage of disease, and histologic grade for 22,616 cases of breast cancer: The basis for a prognostic index
    • Henson, D.E.; Ries, L.; Freedman, L.S.; Carriaga, M. Relationship among outcome, stage of disease, and histologic grade for 22,616 cases of breast cancer: the basis for a prognostic index. Cancer, 1991, 68, 2142-2149.
    • (1991) Cancer , vol.68 , pp. 2142-2149
    • Henson, D.E.1    Ries, L.2    Freedman, L.S.3    Carriaga, M.4
  • 87
    • 0002973612 scopus 로고    scopus 로고
    • Estrogen and Progesterone Receptors
    • In, Harris, J.R., Ed.; Lippencott, Williams, and Wilkins: Philadelphia, PA
    • Elledge, R.M.; Fuqua, S.A. Estrogen and Progesterone Receptors. In Diseases of the Breast, Harris, J.R., Ed.; Lippencott, Williams, and Wilkins: Philadelphia, PA, 2000, pp. 471-488.
    • (2000) Diseases of The Breast , pp. 471-488
    • Elledge, R.M.1    Fuqua, S.A.2
  • 88
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet, 2005, 365, 1687-1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 92
    • 56949103031 scopus 로고    scopus 로고
    • What is triple-negative breast cancer?
    • Irvin, W.J., Jr.; Carey, L.A. What is triple-negative breast cancer? Eur. J. Cancer, 2008, 44, 2799-2805.
    • (2008) Eur. J. Cancer , vol.44 , pp. 2799-2805
    • Irvin Jr., W.J.1    Carey, L.A.2
  • 93
    • 27244443082 scopus 로고    scopus 로고
    • Proliferation marker Ki-67 in early breast cancer
    • Urruticoechea, A.; Smith, I.E.; Dowsett, M. Proliferation marker Ki-67 in early breast cancer. J. Clin. Oncol., 2005, 23, 7212-7220.
    • (2005) J. Clin. Oncol , vol.23 , pp. 7212-7220
    • Urruticoechea, A.1    Smith, I.E.2    Dowsett, M.3
  • 94
    • 33846965616 scopus 로고    scopus 로고
    • Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer
    • IMPACT Trialists Group
    • Dowsett, M.; Smith, I.E.; Ebbs, S.R.; Dixon, J.M.; Skene, A.; A'hern, R.; Salter, J.; Detre, S.; Hills, M.; Walsh, G.; IMPACT Trialists Group. Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. J. Natl. Cancer Inst., 2007, 99, 167-170.
    • (2007) J. Natl. Cancer Inst , vol.99 , pp. 167-170
    • Dowsett, M.1    Smith, I.E.2    Ebbs, S.R.3    Dixon, J.M.4    Skene, A.5    A'Hern, R.6    Salter, J.7    Detre, S.8    Hills, M.9    Walsh, G.10
  • 96
    • 0035865149 scopus 로고    scopus 로고
    • Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer
    • Ravdin, P.M.; Siminoff, L.A.; Davis, G.J.; Mercer, M.B.; Hewlett, J.; Gerson, N.; Parker, H.L. Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer. J. Clin. Oncol., 2001, 19, 980-991.
    • (2001) J. Clin. Oncol , vol.19 , pp. 980-991
    • Ravdin, P.M.1    Siminoff, L.A.2    Davis, G.J.3    Mercer, M.B.4    Hewlett, J.5    Gerson, N.6    Parker, H.L.7
  • 110
    • 36549060490 scopus 로고    scopus 로고
    • The MINDACT trial: The first prospective clinical validation of a genomic tool
    • TRANSBIG Consortium
    • Cardoso, F.; Piccart-Gebhart, M.; van't Veer, L.; Rutgers, E.; TRANSBIG Consortium. The MINDACT trial: the first prospective clinical validation of a genomic tool. Mol. Oncol., 2007, 1, 246-251.
    • (2007) Mol. Oncol , vol.1 , pp. 246-251
    • Cardoso, F.1    Piccart-Gebhart, M.2    van't Veer, L.3    Rutgers, E.4
  • 111
    • 39149113165 scopus 로고    scopus 로고
    • Development of the 21-gene assay and its application in clinical practice and clinical trials
    • Sparano, J.A.; Paik, S. Development of the 21-gene assay and its application in clinical practice and clinical trials. J. Clin. Oncol., 2008, 26, 721-728.
    • (2008) J. Clin. Oncol , vol.26 , pp. 721-728
    • Sparano, J.A.1    Paik, S.2
  • 112
    • 56949083321 scopus 로고    scopus 로고
    • Gene expression predictors in breast cancer: Current status, limitations and perspectives
    • Desmedt, C.; Ruíz-García, E.; André, F. Gene expression predictors in breast cancer: current status, limitations and perspectives. Eur. J. Cancer, 2008, 44, 2714-2720.
    • (2008) Eur. J. Cancer , vol.44 , pp. 2714-2720
    • Desmedt, C.1    Ruíz-García, E.2    André, F.3
  • 114
  • 115
    • 41549100210 scopus 로고    scopus 로고
    • Multigene predictors in early-stage breast cancer: Moving in or moving out?
    • Ross, J.S. Multigene predictors in early-stage breast cancer: moving in or moving out? Expert Rev. Mol. Diagn., 2008, 8, 129-135.
    • (2008) Expert Rev. Mol. Diagn , vol.8 , pp. 129-135
    • Ross, J.S.1
  • 116
    • 77952516598 scopus 로고    scopus 로고
    • Pharmacogenetics, Pharmaco-genomics, and Predicting Response to Therapy
    • In, Ross, J.S.; Hortobagyi, G.N., Eds.; Jones and Bartlett Publishers: Sudbury, MA
    • Pusztai, L.; Stec, J.; Ayers, M.; Ross, J.S.; Wagner, P.; Rouzier, R.; Symmans, F.; Hortobagyi, G.N. Pharmacogenetics, Pharmaco-genomics, and Predicting Response to Therapy. In Molecular Oncology of Breast Cancer, Ross, J.S.; Hortobagyi, G.N., Eds.; Jones and Bartlett Publishers: Sudbury, MA, 2005, pp. 439-456.
    • (2005) Molecular Oncology of Breast Cancer , pp. 439-456
    • Pusztai, L.1    Stec, J.2    Ayers, M.3    Ross, J.S.4    Wagner, P.5    Rouzier, R.6    Symmans, F.7    Hortobagyi, G.N.8
  • 117
    • 0037364074 scopus 로고    scopus 로고
    • Tamoxifen: A most unlikely pioneering medicine
    • Jordan, V.C. Tamoxifen: a most unlikely pioneering medicine. Nat. Rev. Drug Discov., 2003, 2, 205-213.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 205-213
    • Jordan, V.C.1
  • 119
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford, L.D. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics, 2002, 3, 229-243.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 122
  • 124
    • 0242457704 scopus 로고    scopus 로고
    • Hormonal effects of aromatase inhibitors: Focus on premenopausal effects and interaction with tamoxifen
    • Dowsett, M.; Haynes, B.P. Hormonal effects of aromatase inhibitors: focus on premenopausal effects and interaction with tamoxifen. J. Steroid Biochem. Mol. Biol., 2003, 86, 255-263.
    • (2003) J. Steroid Biochem. Mol. Biol , vol.86 , pp. 255-263
    • Dowsett, M.1    Haynes, B.P.2
  • 129
    • 31644439702 scopus 로고    scopus 로고
    • Herceptin: Mechanisms of action and resistance
    • Nahta, R.; Esteva, F.J. Herceptin: mechanisms of action and resistance. Cancer Lett., 2006, 232, 123-138.
    • (2006) Cancer Lett , vol.232 , pp. 123-138
    • Nahta, R.1    Esteva, F.J.2
  • 130
    • 2142714017 scopus 로고    scopus 로고
    • Monoclonal antibodies as therapeutic agents for cancer
    • Harris, M. Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol., 2004, 5, 292-302.
    • (2004) Lancet Oncol , vol.5 , pp. 292-302
    • Harris, M.1
  • 131
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro, T.; Beerli, R.R.; Maurer, F.; Koziczak, M.; Barbas, C.F., III, Hynes, N.E. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc. Natl. Acad. Sci. USA, 2003, 100, 8933-8938.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3    Koziczak, M.4    Barbas III, C.F.5    Hynes, N.E.6
  • 134
    • 37549021876 scopus 로고    scopus 로고
    • Advances in the treatment of breast cancer
    • Moulder, S.; Hortobagyi, G.N. Advances in the treatment of breast cancer. Clin. Pharmacol. Ther., 2008, 83, 26-36.
    • (2008) Clin. Pharmacol. Ther , vol.83 , pp. 26-36
    • Moulder, S.1    Hortobagyi, G.N.2
  • 139
    • 33644647219 scopus 로고    scopus 로고
    • Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer
    • Bosch, T.M.; Meijerman, I.; Beijnen, J.H.; Schellens, J.H.M. Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer. Clin. Pharmacokinet., 2006, 45, 253-285.
    • (2006) Clin. Pharmacokinet , vol.45 , pp. 253-285
    • Bosch, T.M.1    Meijerman, I.2    Beijnen, J.H.3    Schellens, J.H.M.4
  • 140
    • 65049085938 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacogenomics in breast cancer chemotherapy
    • Marsh, S.; Liu, G. Pharmacokinetics and pharmacogenomics in breast cancer chemotherapy. Adv. Drug Deliv. Rev., 2009, 61, 381-387.
    • (2009) Adv. Drug Deliv. Rev , vol.61 , pp. 381-387
    • Marsh, S.1    Liu, G.2
  • 141
    • 67749114265 scopus 로고    scopus 로고
    • CYP2D6 and tamoxifen: DNA matters in breast cancer
    • Hoskins, J.M.; Carey, L.A.; McLeod, H.L. CYP2D6 and tamoxifen: DNA matters in breast cancer. Nat. Rev. Cancer, 2009, 9, 576-586.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 576-586
    • Hoskins, J.M.1    Carey, L.A.2    McLeod, H.L.3
  • 143
    • 13444249478 scopus 로고    scopus 로고
    • Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer
    • Ambrosone, C.B.; Ahn, J.; Singh, K.K.; Rezaishiraz, H.; Furberg, H.; Sweeney, C.; Coles, B.; Trovato, A. Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer. Cancer Res., 2005, 65, 1105-1111.
    • (2005) Cancer Res , vol.65 , pp. 1105-1111
    • Ambrosone, C.B.1    Ahn, J.2    Singh, K.K.3    Rezaishiraz, H.4    Furberg, H.5    Sweeney, C.6    Coles, B.7    Trovato, A.8
  • 145
    • 62249112106 scopus 로고    scopus 로고
    • Personalized cancer therapy gets closer
    • Check Hayden, E. Personalized cancer therapy gets closer. Nature, 2009, 458, 131-132.
    • (2009) Nature , vol.458 , pp. 131-132
    • Check Hayden, E.1
  • 146
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • Manolio, T.A.; Brooks, L.D.; Collins, F.S. A HapMap harvest of insights into the genetics of common disease. J. Clin. Invest., 2008, 118, 1590-1605.
    • (2008) J. Clin. Invest , vol.118 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 147
    • 3242743707 scopus 로고    scopus 로고
    • Genetic testing and pharmacogenomics: Issues for determining the impact to healthcare delivery and costs
    • Phillips, K.A.; Veenstra, D.L.; Ramsey, S.D.; Van Bebber, S.L.; Sakowski, J. Genetic testing and pharmacogenomics: issues for determining the impact to healthcare delivery and costs. Am. J. Manag. Care, 2004, 10, 425-432.
    • (2004) Am. J. Manag. Care , vol.10 , pp. 425-432
    • Phillips, K.A.1    Veenstra, D.L.2    Ramsey, S.D.3    van Bebber, S.L.4    Sakowski, J.5
  • 148
    • 69349102026 scopus 로고    scopus 로고
    • The dawning era of personalized medicine exposes a gap in medical education
    • Salari, K. The dawning era of personalized medicine exposes a gap in medical education. PLoS Med., 2009, 6, e1000138.
    • (2009) PLoS Med , vol.6
    • Salari, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.