-
1
-
-
84925601355
-
-
Accessed 9 Sept 2014.
-
Cancer IAfRo. Globocan 2012. http://globocan.iarc.fr . Accessed 9 Sept 2014.
-
(2012)
-
-
-
2
-
-
84893109382
-
Immunosenescence and cancer
-
Fulop T, Larbi A, Witkowski JM, Kotb R, Hirokawa K, Pawelec G. Immunosenescence and cancer. Crit Rev Oncog. 2013;18:489-513.
-
(2013)
Crit Rev Oncog.
, vol.18
, pp. 489-513
-
-
Fulop, T.1
Larbi, A.2
Witkowski, J.M.3
Kotb, R.4
Hirokawa, K.5
Pawelec, G.6
-
3
-
-
84907651094
-
Antibody therapies for melanoma: New and emerging opportunities to activate immunity (Review)
-
Malas S, Harrasser M, Lacy KE, Karagiannis SN. Antibody therapies for melanoma: New and emerging opportunities to activate immunity (Review). Oncol Rep. 2014;32:875-86. doi:10.3892/or.2014.3275.
-
(2014)
Oncol Rep.
, vol.32
, pp. 875-886
-
-
Malas, S.1
Harrasser, M.2
Lacy, K.E.3
Karagiannis, S.N.4
-
4
-
-
84884586706
-
Checkpoint modulation in melanoma: an update on ipilimumab and future directions
-
Page DB, Postow MA, Callahan MK, Wolchok JD. Checkpoint modulation in melanoma: an update on ipilimumab and future directions. Curr Oncol Rep. 2013;15:500-8. doi:10.1007/s11912-013-0337-1.
-
(2013)
Curr Oncol Rep.
, vol.15
, pp. 500-508
-
-
Page, D.B.1
Postow, M.A.2
Callahan, M.K.3
Wolchok, J.D.4
-
5
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443-54. doi:10.1056/NEJMoa1200690.
-
(2012)
N Engl J Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
6
-
-
84876942195
-
Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer
-
Aerts JG, Hegmans JP. Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer. Cancer Res. 2013;73:2381-8. doi:10.1158/0008-5472.CAN-12-3932.
-
(2013)
Cancer Res.
, vol.73
, pp. 2381-2388
-
-
Aerts, J.G.1
Hegmans, J.P.2
-
7
-
-
84864008345
-
Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis
-
Weide B, Zelba H, Derhovanessian E, Pflugfelder A, Eigentler TK, Di Giacomo AM, et al. Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis. J Clin Oncol. 2012;30:1835-41. doi:10.1200/JCO.2011.40.2271.
-
(2012)
J Clin Oncol.
, vol.30
, pp. 1835-1841
-
-
Weide, B.1
Zelba, H.2
Derhovanessian, E.3
Pflugfelder, A.4
Eigentler, T.K.5
Giacomo, A.M.6
-
8
-
-
0028857587
-
Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide
-
Peoples GE, Goedegebuure PS, Smith R, Linehan DC, Yoshino I, Eberlein TJ. Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide. Proc Natl Acad Sci U S A. 1995;92:432-6.
-
(1995)
Proc Natl Acad Sci U S A.
, vol.92
, pp. 432-436
-
-
Peoples, G.E.1
Goedegebuure, P.S.2
Smith, R.3
Linehan, D.C.4
Yoshino, I.5
Eberlein, T.J.6
-
9
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science. 1989;244:707-12.
-
(1989)
Science.
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
-
10
-
-
77956070565
-
Anti-HER2 vaccines: new prospects for breast cancer therapy
-
Ladjemi MZ, Jacot W, Chardes T, Pelegrin A, Navarro-Teulon I. Anti-HER2 vaccines: new prospects for breast cancer therapy. Cancer Immunol Immunother. 2010;59:1295-312. doi:10.1007/s00262-010-0869-2.
-
(2010)
Cancer Immunol Immunother.
, vol.59
, pp. 1295-1312
-
-
Ladjemi, M.Z.1
Jacot, W.2
Chardes, T.3
Pelegrin, A.4
Navarro-Teulon, I.5
-
11
-
-
84884133665
-
Modulation of CD8(+) T-cell activation events by monocytic and granulocytic myeloid-derived suppressor cells
-
Schouppe E, Van Overmeire E, Laoui D, Keirsse J, Van Ginderachter JA. Modulation of CD8(+) T-cell activation events by monocytic and granulocytic myeloid-derived suppressor cells. Immunobiology. 2013;218:1385-91. doi:10.1016/j.imbio.2013.07.003.
-
(2013)
Immunobiology.
, vol.218
, pp. 1385-1391
-
-
Schouppe, E.1
Overmeire, E.2
Laoui, D.3
Keirsse, J.4
Ginderachter, J.A.5
-
12
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9. doi:10.1038/nm1093.
-
(2004)
Nat Med.
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
13
-
-
84866910216
-
Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma
-
Gros A, Turcotte S, Wunderlich JR, Ahmadzadeh M, Dudley ME, Rosenberg SA. Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma. Clin Cancer Res. 2012;18:5212-23. doi:10.1158/1078-0432.CCR-12-1108.
-
(2012)
Clin Cancer Res.
, vol.18
, pp. 5212-5223
-
-
Gros, A.1
Turcotte, S.2
Wunderlich, J.R.3
Ahmadzadeh, M.4
Dudley, M.E.5
Rosenberg, S.A.6
-
14
-
-
34247261531
-
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
-
Bates GJ, Fox SB, Han C, Leek RD, Garcia JF, Harris AL, et al. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol. 2006;24:5373-80. doi:10.1200/JCO.2006.05.9584.
-
(2006)
J Clin Oncol.
, vol.24
, pp. 5373-5380
-
-
Bates, G.J.1
Fox, S.B.2
Han, C.3
Leek, R.D.4
Garcia, J.F.5
Harris, A.L.6
-
15
-
-
20444464066
-
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer
-
Sharma S, Yang SC, Zhu L, Reckamp K, Gardner B, Baratelli F, et al. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res. 2005;65:5211-20. doi:10.1158/0008-5472.CAN-05-0141.
-
(2005)
Cancer Res.
, vol.65
, pp. 5211-5220
-
-
Sharma, S.1
Yang, S.C.2
Zhu, L.3
Reckamp, K.4
Gardner, B.5
Baratelli, F.6
-
16
-
-
3142737258
-
Foxp3 expressing CD4 + CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
-
Viguier M, Lemaitre F, Verola O, Cho MS, Gorochov G, Dubertret L, et al. Foxp3 expressing CD4 + CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol. 2004;173:1444-53.
-
(2004)
J Immunol.
, vol.173
, pp. 1444-1453
-
-
Viguier, M.1
Lemaitre, F.2
Verola, O.3
Cho, M.S.4
Gorochov, G.5
Dubertret, L.6
-
17
-
-
84872932778
-
Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer
-
Lin YC, Mahalingam J, Chiang JM, Su PJ, Chu YY, Lai HY, et al. Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer. Int J Cancer. 2013;132:1341-50. doi:10.1002/ijc.27784.
-
(2013)
Int J Cancer.
, vol.132
, pp. 1341-1350
-
-
Lin, Y.C.1
Mahalingam, J.2
Chiang, J.M.3
Su, P.J.4
Chu, Y.Y.5
Lai, H.Y.6
-
18
-
-
66949171924
-
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
-
Miyara M, Yoshioka Y, Kitoh A, Shima T, Wing K, Niwa A, et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity. 2009;30:899-911. doi:10.1016/j.immuni.2009.03.019.
-
(2009)
Immunity.
, vol.30
, pp. 899-911
-
-
Miyara, M.1
Yoshioka, Y.2
Kitoh, A.3
Shima, T.4
Wing, K.5
Niwa, A.6
-
20
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9:162-74. doi:10.1038/nri2506.
-
(2009)
Nat Rev Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
21
-
-
34447258415
-
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
-
Filipazzi P, Valenti R, Huber V, Pilla L, Canese P, Iero M, et al. Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol. 2007;25:2546-53. doi:10.1200/JCO.2006.08.5829.
-
(2007)
J Clin Oncol.
, vol.25
, pp. 2546-2553
-
-
Filipazzi, P.1
Valenti, R.2
Huber, V.3
Pilla, L.4
Canese, P.5
Iero, M.6
-
22
-
-
77955549860
-
Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity
-
Ostrand-Rosenberg S. Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol Immunother. 2010;59:1593-600. doi:10.1007/s00262-010-0855-8.
-
(2010)
Cancer Immunol Immunother.
, vol.59
, pp. 1593-1600
-
-
Ostrand-Rosenberg, S.1
-
23
-
-
84866916560
-
Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives
-
Raber P, Ochoa AC, Rodriguez PC. Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol Invest. 2012;41:614-34. doi:10.3109/08820139.2012.680634.
-
(2012)
Immunol Invest.
, vol.41
, pp. 614-634
-
-
Raber, P.1
Ochoa, A.C.2
Rodriguez, P.C.3
-
24
-
-
84896523495
-
Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells
-
Weide B, Martens A, Zelba H, Stutz C, Derhovanessian E, Di Giacomo AM, et al. Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells. Clin Cancer Res. 2014;20:1601-9. doi:10.1158/1078-0432.CCR-13-2508.
-
(2014)
Clin Cancer Res.
, vol.20
, pp. 1601-1609
-
-
Weide, B.1
Martens, A.2
Zelba, H.3
Stutz, C.4
Derhovanessian, E.5
Giacomo, A.M.6
-
25
-
-
80054102628
-
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
-
Gabitass RF, Annels NE, Stocken DD, Pandha HA, Middleton GW. Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol Immunother. 2011;60:1419-30. doi:10.1007/s00262-011-1028-0.
-
(2011)
Cancer Immunol Immunother.
, vol.60
, pp. 1419-1430
-
-
Gabitass, R.F.1
Annels, N.E.2
Stocken, D.D.3
Pandha, H.A.4
Middleton, G.W.5
-
26
-
-
84894501478
-
Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab
-
Meyer C, Cagnon L, Costa-Nunes CM, Baumgaertner P, Montandon N, Leyvraz L, et al. Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab. Cancer Immunol Immunother. 2014;63:247-57. doi:10.1007/s00262-013-1508-5.
-
(2014)
Cancer Immunol Immunother.
, vol.63
, pp. 247-257
-
-
Meyer, C.1
Cagnon, L.2
Costa-Nunes, C.M.3
Baumgaertner, P.4
Montandon, N.5
Leyvraz, L.6
-
27
-
-
84862776821
-
The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines
-
McElhaney JE, Zhou X, Talbot HK, Soethout E, Bleackley RC, Granville DJ, et al. The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines. Vaccine. 2012;30:2060-7. doi:10.1016/j.vaccine.2012.01.015.
-
(2012)
Vaccine.
, vol.30
, pp. 2060-2067
-
-
McElhaney, J.E.1
Zhou, X.2
Talbot, H.K.3
Soethout, E.4
Bleackley, R.C.5
Granville, D.J.6
-
28
-
-
84860700518
-
Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
Mittendorf EA, Clifton GT, Holmes JP, Clive KS, Patil R, Benavides LC, et al. Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer. 2012;118:2594-602. doi:10.1002/cncr.26574.
-
(2012)
Cancer.
, vol.118
, pp. 2594-2602
-
-
Mittendorf, E.A.1
Clifton, G.T.2
Holmes, J.P.3
Clive, K.S.4
Patil, R.5
Benavides, L.C.6
-
29
-
-
84902079425
-
The HER2 peptide nelipepimut-S (E75) vaccine (NeuVax) in breast cancer patients at risk for recurrence: correlation of immunologic data with clinical response
-
Schneble EJ, Berry JS, Trappey FA, Clifton GT, Ponniah S, Mittendorf E, et al. The HER2 peptide nelipepimut-S (E75) vaccine (NeuVax) in breast cancer patients at risk for recurrence: correlation of immunologic data with clinical response. Immunotherapy. 2014;6:519-31. doi:10.2217/imt.14.22.
-
(2014)
Immunotherapy.
, vol.6
, pp. 519-531
-
-
Schneble, E.J.1
Berry, J.S.2
Trappey, F.A.3
Clifton, G.T.4
Ponniah, S.5
Mittendorf, E.6
-
30
-
-
65349097929
-
The impact of HER2/neu expression level on response to the E75 vaccine: from U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02
-
Benavides LC, Gates JD, Carmichael MG, Patil R, Holmes JP, Hueman MT, et al. The impact of HER2/neu expression level on response to the E75 vaccine: from U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Clin Cancer Res. 2009;15:2895-904. doi:10.1158/1078-0432.CCR-08-1126.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2895-2904
-
-
Benavides, L.C.1
Gates, J.D.2
Carmichael, M.G.3
Patil, R.4
Holmes, J.P.5
Hueman, M.T.6
-
31
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother. 2009;58:49-59. doi:10.1007/s00262-008-0523-4.
-
(2009)
Cancer Immunol Immunother.
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
32
-
-
34447118098
-
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer
-
Nagaraj S, Gupta K, Pisarev V, Kinarsky L, Sherman S, Kang L, et al. Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer. Nat Med. 2007;13:828-35. doi:10.1038/nm1609.
-
(2007)
Nat Med.
, vol.13
, pp. 828-835
-
-
Nagaraj, S.1
Gupta, K.2
Pisarev, V.3
Kinarsky, L.4
Sherman, S.5
Kang, L.6
-
33
-
-
77953141534
-
Immature immunosuppressive CD14 + HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign
-
Poschke I, Mougiakakos D, Hansson J, Masucci GV, Kiessling R. Immature immunosuppressive CD14 + HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res. 2010;70:4335-45. doi:10.1158/0008-5472.CAN-09-3767.
-
(2010)
Cancer Res.
, vol.70
, pp. 4335-4345
-
-
Poschke, I.1
Mougiakakos, D.2
Hansson, J.3
Masucci, G.V.4
Kiessling, R.5
-
34
-
-
77950829023
-
Mechanism of T cell tolerance induced by myeloid-derived suppressor cells
-
Nagaraj S, Schrum AG, Cho HI, Celis E, Gabrilovich DI. Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. J Immunol. 2010;184:3106-16. doi:10.4049/jimmunol.0902661.
-
(2010)
J Immunol.
, vol.184
, pp. 3106-3116
-
-
Nagaraj, S.1
Schrum, A.G.2
Cho, H.I.3
Celis, E.4
Gabrilovich, D.I.5
-
35
-
-
34548162594
-
Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival
-
Griffiths RW, Elkord E, Gilham DE, Ramani V, Clarke N, Stern PL, et al. Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival. Cancer Immunol Immunother. 2007;56:1743-53. doi:10.1007/s00262-007-0318-z.
-
(2007)
Cancer Immunol Immunother.
, vol.56
, pp. 1743-1753
-
-
Griffiths, R.W.1
Elkord, E.2
Gilham, D.E.3
Ramani, V.4
Clarke, N.5
Stern, P.L.6
-
36
-
-
0036721629
-
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
-
Liyanage UK, Moore TT, Joo HG, Tanaka Y, Herrmann V, Doherty G, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol. 2002;169:2756-61.
-
(2002)
J Immunol.
, vol.169
, pp. 2756-2761
-
-
Liyanage, U.K.1
Moore, T.T.2
Joo, H.G.3
Tanaka, Y.4
Herrmann, V.5
Doherty, G.6
|