Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon

Kobe Journal of Medical Sciences

Volumn 52, Issue 4, 2006, Pages 85-95

  Imanishi, Tatsuya ^a   Kamigaki, Takashi ^a   Nakamura, Tetsu ^a   Hayashi, Shun ^a   Yasuda, Takashi ^a   Kawasaki, Kentaro ^a   Takase, Shiro ^a   Ajiki, Tetsuo ^a   Kuroda, Yoshikazu ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

2 microglobulin; Antigen processing; Gastrointestinal cancer; LMP2; MHC class I

Indexed keywords

BETA 2 MICROGLOBULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ARTICLE; BILIARY TRACT CANCER; CARCINOMA CELL; CELL LINE; COLON CANCER; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; FLOW CYTOMETRY; GENE EXPRESSION; HEPATOBILIARY SYSTEM; HUMAN; HUMAN CELL; PANCREAS CELL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTIGEN PRESENTATION; ANTIGENS, NEOPLASM; ATP-BINDING CASSETTE TRANSPORTERS; BETA 2-MICROGLOBULIN; BILIARY TRACT NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYSTEINE ENDOPEPTIDASES; DIGESTIVE SYSTEM NEOPLASMS; GENE EXPRESSION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; PANCREATIC NEOPLASMS; TRANSFECTION;

EID: 33748376676     PISSN: 00232513     EISSN: 18830498     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Hill, A., Ploegh, H. 1995. Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen. Proc Natl Acad Sci USA 92:341-343..
2. Grandea, A.G., 3rd, Lehner, P.J., Cresswell, P., Spies, T. 1997. Regulation of MHC class I heterodimer stability and interaction with TAP by tapasin. Immunogenetics 46:477-483..
3. Sadasivan, B., Lehner, P.J., Ortmann, B., Spies, T., Cresswell, P. 1996. Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity 5:103-114..
4. Higgins, C.F. 1995. The ABC of channel regulation. Cell 82:693-696..
5. Griffin, T.A., Nandi, D., Cruz, M., Fehling, H.J., Kaer, L.V., Monaco, J.J., Colbert, R.A. 1998. Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits. J Exp Med 187:97-104.
6. Rock, K.L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., Goldberg, A.L. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78:761-771..
7. Fehling, H.J., Swat, W., Laplace, C., Kuhn, R., Rajewsky, K., Muller, U., von Boehmer, H. 1994. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science 265:1234-1237.
8. Germain, R.N. 1994. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 76:287-299..
9. Perarnau, B., Siegrist, C.A., Gillet, A., Vincent, C., Kimura, S., Lemonnier, F.A. 1990. Beta 2-microglobulin restriction of antigen presentation. Nature 346:751-754.
10. Williams, D.B., Barber, B.H., Flavell, R.A., Allen, H. 1989. Role of beta2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules. J Immunol 142:2796-2806.
11. D'Urso, C.M., Wang, Z.G., Cao, Y., Tatake, R., Zeff, R.A., Ferrone, S. 1991. Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in β2m gene expression. J Clin Invest 87:284-292.
12. Wang, Z., Cao, Y., Albino, A.P., Zeff, R.A., Houghton, A., Ferrone, S. 1993. Lack of HLA class I antigen expression by melanoma cells SK-MEL-33 caused by a reading frameshift in beta 2-microglobulin messenger RNA. J Clin Invest 91:684-692.
13. Hicklin, D.J., Wang, Z., Arienti, F., Rivoltini, L., Parmiani, G., Ferrone, S. 1998. Beta2-microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma. J Clin Invest 101:2720-2729.
14. Gattoni-Cell,i S., Kirsch, K., Timpane, R., Isselbacher, K.J. 1992. β2-microglobulin gene is mutated in a human colon cancer cell line (HCT) deficient in the expression of HLA class I antigens on the cell sruface. Cancer Res 52:1201-1204.
15. Bicknell, D.C., Rowan, A., Bodmer, W.F. 1994. Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors. Proc Natl Acad Sci USA 91:4751-4756.
16. Yoon, S.J., Kang, J.O., Park, J.S., Kim, N.K., Heo, D.S. 2000. Reduced expression of MHC class I antigen in human cancer cell lines with defective LMP-7. Anticancer Res 20:949-953.
17. Alimonti, J., Zhang, Q.J., Gabathuler, R., Reid, G,. Chen, S.S., Jefferies, W.A. 2000. TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nat Biotechnol 18:515-520.
18. Tanaka, K., Yoshioka, T., Bieberich, C., Jay, G. 1988. Role of the major histocompatibility complex class I antigens in tumor growth and metastasis. Annu Rev Immunol 6:359-380.
19. Natali, P.G., Nicotra, M.R., Bigotti, A., Venturo, I., Marcenaro, L., Giacomini, P., Russo, C. 1989. elective changes in expression of HLA class I polymorphic determinants in human solid tumors. Proc Natl Acad Sci USA 86:6719-6723.
20. Ferrone, S., Marincola, F.M. 1995. Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunol Today 16:487-494.
21. Kageshita, T., Hirai, S., Ono, T., Hicklin, D.J., Ferrone, S. 1999. Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression. Am J Pathol 154:745-754.
22. Momburg, F., Moller, P., Moldenhauer, G., Hammerling, G..J. 1986. Loss of HLA-A, B, C in colorectal carcinoma is related to the degree of de-differentiation. J Immunogenet 13:195-199.
23. Csiba, A., Whitwell, H.L., Moore, M. 1984. Distribution of histocompatibility and leucocyte differentiation antigens in normal human colon and in benign and malignant colonic neoplasms. Br J Cancer 50:699-709.
24. Yewdell, J.W., Bennink, J.R. 1992. Cell biology of antigen processing and presentation to major histocompatibility complex class I molecule-restricted T lymphocytes. Adv Immunol 52:1-123.
25. Germain, R.N., Margulies, D.H. 1993. The biochemistry and cell biology of antigen processing and presentation. Annu Rev Immunol 11:403-450.
26. Matsui, M., Ikeda, M., Akatsuka, T. 2001. High expression of HLA-A2 on an oral squamous cell carcinoma with down- regulated transporter for antigen presentation. Biochem Biophys Res Commun 280:1008-1014.
27. Johnsen, A., France, J., Sy, M.S., Harding, C.V. 1998. Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines. Cancer Res 58:3660-3667.
28. Kang, J.K., Yoon, S.J., Kim N.K., Heo, D.S. 2000. The expression of MHC class I, TAP1/2, and LMP2/7 gene in human gastric cancer cell lines. Int J Oncol 16:1159-1163.
29. Menon, A.G., Morreau, H., Tollenaar, R.A., Alphenaar, E., Van Puijenbroek, M., Putter, H., Janssen-Van, Rhijn, C.M., Van, De, Velde, C.J., Fleuren, G.J., Kuppen, P.J. 2002. Down-regulation of HLA-A expression correlates with a better prognosis in colorectal cancer patients. Lab Invest 82:1725-1733.
30. Driscoll, J., Brown, M.G., Finley, D., Monaco, J.J. 1993. MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature 365:262-264.
31. Wright, K.L., White, L.C., Kelly, A., Beck, S., Trowsdale, J., Ting, J.P-Y. 1995. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J. Exp. Med., 181:1459-1471.