Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice

Neuropharmacology

Volumn 105, Issue , 2016, Pages 285-297

  Sharma, Sorabh ^a   Taliyan, Rajeev ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Alzheimer's disease; Cognitive deficit; Histone deacetylases; Insulin resistance; Suberoylanilide hydroxamic acid

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HISTONE H3; INSULIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VORINOSTAT; ENZYME INHIBITOR; HISTONE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIORAL SCIENCE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; EPIGENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HIPPOCAMPUS; HISTONE ACETYLATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; MALE; MEMORY DISORDER; MENTAL PERFORMANCE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; ANIMAL BEHAVIOR; AVOIDANCE BEHAVIOR; COGNITION DISORDERS; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; MEMORY DISORDERS; METABOLISM; MOTOR ACTIVITY; SPATIAL MEMORY;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; COGNITION DISORDERS; DIET, HIGH-FAT; ENZYME INHIBITORS; EPIGENESIS, GENETIC; HIPPOCAMPUS; HISTONE DEACETYLASE INHIBITORS; HISTONES; HYDROXAMIC ACIDS; INSULIN RESISTANCE; MALE; MEMORY DISORDERS; MICE; MOTOR ACTIVITY; SPATIAL MEMORY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84961333110     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2016.01.025     Document Type: Article

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