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Volumn 57, Issue , 2016, Pages 125-133

Multiple inflammasome complexes are activated in autistic spectrum disorders

Author keywords

Autistic spectrum disorders (ASD); IFABP; Inflammasome; Neuroinflammation; NLRP3

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 5; CRYOPYRIN; FATTY ACID BINDING PROTEIN 2; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 33; INTERLEUKIN 37; LIPOPOLYSACCHARIDE; PROTEIN AIM2; PROTEIN PYCARD; UNCLASSIFIED DRUG; AIM2 PROTEIN, HUMAN; DNA BINDING PROTEIN; FABP2 PROTEIN, HUMAN; FATTY ACID BINDING PROTEIN; INTERLEUKIN DERIVATIVE; NLRP3 PROTEIN, HUMAN;

EID: 84961233504     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2016.03.009     Document Type: Article
Times cited : (71)

References (57)
  • 1
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini, L., Martinon, F., Burns, K., McDermott, M.F., Hawkins, P.N., Tschopp, J., NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20 (2004), 319–325.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 2
    • 84892165503 scopus 로고    scopus 로고
    • Association of social and cognitive impairment and biomarkers in autism spectrum disorders
    • Alabdali, A., Al-Ayadhi, L., El-Ansary, A., Association of social and cognitive impairment and biomarkers in autism spectrum disorders. J. Neuroinflam. 11 (2014), 4–12.
    • (2014) J. Neuroinflam. , vol.11 , pp. 4-12
    • Alabdali, A.1    Al-Ayadhi, L.2    El-Ansary, A.3
  • 3
    • 80051926552 scopus 로고    scopus 로고
    • The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB-stimulated gene transcription
    • Ali, S., Mohs, A., Thomas, M., Klare, J., Ross, R., Schmitz, M.L., Martin, M.U., The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB-stimulated gene transcription. J. Immunol. 187 (2011), 1609–1616.
    • (2011) J. Immunol. , vol.187 , pp. 1609-1616
    • Ali, S.1    Mohs, A.2    Thomas, M.3    Klare, J.4    Ross, R.5    Schmitz, M.L.6    Martin, M.U.7
  • 4
    • 0003472502 scopus 로고    scopus 로고
    • DSM 5. Diagnostic and Statistical Manual of Mental Disorders
    • fifth ed. American Psychiatric Publishing Washington, DC
    • American Psychiatric Association, DSM 5. Diagnostic and Statistical Manual of Mental Disorders. fifth ed., 2013, American Psychiatric Publishing, Washington, DC.
    • (2013)
    • American Psychiatric Association1
  • 5
    • 33644951883 scopus 로고    scopus 로고
    • Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms
    • Ashwood, P., Wakefield, A.J., Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms. J. Neuroimmunol. 173 (2006), 126–134.
    • (2006) J. Neuroimmunol. , vol.173 , pp. 126-134
    • Ashwood, P.1    Wakefield, A.J.2
  • 6
    • 78649322790 scopus 로고    scopus 로고
    • Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
    • Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I., Van de Water, J., Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav. Immun. 25 (2011), 40–45.
    • (2011) Brain Behav. Immun. , vol.25 , pp. 40-45
    • Ashwood, P.1    Krakowiak, P.2    Hertz-Picciotto, I.3    Hansen, R.4    Pessah, I.5    Van de Water, J.6
  • 10
    • 79960542894 scopus 로고    scopus 로고
    • Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
    • Bauernfeind, F., Bartok, E., Rieger, A., Franchi, L., Núñez, G., Hornung, V., Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J. Immunol. 187 (2011), 613–617.
    • (2011) J. Immunol. , vol.187 , pp. 613-617
    • Bauernfeind, F.1    Bartok, E.2    Rieger, A.3    Franchi, L.4    Núñez, G.5    Hornung, V.6
  • 12
    • 69549119940 scopus 로고    scopus 로고
    • Molecular mechanisms involved in inflammasome activation
    • Bryant, C., Fitzgerald, K.A., Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 19 (2009), 455–464.
    • (2009) Trends Cell Biol. , vol.19 , pp. 455-464
    • Bryant, C.1    Fitzgerald, K.A.2
  • 17
    • 81155159738 scopus 로고    scopus 로고
    • Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management
    • de Theije, C.G., Wu, J., da Silva, S.L., Kamphuis, P.J., Garssen, J., Korte, S.M., Kraneveld, A.D., Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management. Eur. J. Pharmacol. 668 (2011), 70–80.
    • (2011) Eur. J. Pharmacol. , vol.668 , pp. 70-80
    • de Theije, C.G.1    Wu, J.2    da Silva, S.L.3    Kamphuis, P.J.4    Garssen, J.5    Korte, S.M.6    Kraneveld, A.D.7
  • 19
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert, C., Pétrilli, V., Van Bruggen, R., Steele, C., Mossman, B.T., Tschopp, J., Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320 (2008), 674–677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Pétrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 20
    • 0032698199 scopus 로고    scopus 로고
    • Plasma intestinal fatty acid binding protein in neonates with necrotizing entercolitis: a pilot study
    • Edelson, M.B., Sonnino, R.E., Bagwell, C.E., Lieberman, J.M., Marks, W.H., Rozycki, H., Plasma intestinal fatty acid binding protein in neonates with necrotizing entercolitis: a pilot study. J. Pediatr. Surg. 34 (1999), 1452–1457.
    • (1999) J. Pediatr. Surg. , vol.34 , pp. 1452-1457
    • Edelson, M.B.1    Sonnino, R.E.2    Bagwell, C.E.3    Lieberman, J.M.4    Marks, W.H.5    Rozycki, H.6
  • 21
    • 71749094505 scopus 로고    scopus 로고
    • Differential monocyte responses to TLR ligands in children with autism spectrum disorders
    • Enstrom, A.M., Onore, C.E., Van de Water, J.A., Ashwood, P., Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain Behav. Immun. 24 (2010), 64–71.
    • (2010) Brain Behav. Immun. , vol.24 , pp. 64-71
    • Enstrom, A.M.1    Onore, C.E.2    Van de Water, J.A.3    Ashwood, P.4
  • 23
    • 17644449656 scopus 로고    scopus 로고
    • Plasma concentration of intestinal- and liver-FABP in neonates suffering from necrotizing enterocolitis and in healthy preterm neonates
    • Guthmann, F., Börchers, T., Wolfrum, C., Wustrack, T., Bartholomäus, S., Spener, F., Plasma concentration of intestinal- and liver-FABP in neonates suffering from necrotizing enterocolitis and in healthy preterm neonates. Mol. Cell. Biochem. 239 (2002), 227–234.
    • (2002) Mol. Cell. Biochem. , vol.239 , pp. 227-234
    • Guthmann, F.1    Börchers, T.2    Wolfrum, C.3    Wustrack, T.4    Bartholomäus, S.5    Spener, F.6
  • 25
    • 84918802996 scopus 로고    scopus 로고
    • Novel roles for caspase-8 in IL-1β and inflammasome regulation
    • Gurung, P., Kanneganti, T.D., Novel roles for caspase-8 in IL-1β and inflammasome regulation. Am. J. Pathol. 185 (2015), 17–25.
    • (2015) Am. J. Pathol. , vol.185 , pp. 17-25
    • Gurung, P.1    Kanneganti, T.D.2
  • 27
    • 79960574244 scopus 로고    scopus 로고
    • Aberrant immune responses in a mouse with behavioral disorders
    • Heo, Y., Zhang, Y., Gao, D., Miller, V.M., Lawrence, D.A., Aberrant immune responses in a mouse with behavioral disorders. PLoS ONE, 6, 2011, e20912, 10.1371/journal.pone.0020912.
    • (2011) PLoS ONE , vol.6 , pp. e20912
    • Heo, Y.1    Zhang, Y.2    Gao, D.3    Miller, V.M.4    Lawrence, D.A.5
  • 29
    • 80052175401 scopus 로고    scopus 로고
    • Intracellular sensing of microbes and danger signals by the inflammasomes
    • Horvath, G.L., Schrum, J.E., De Nardo, C.M., Latz, E., Intracellular sensing of microbes and danger signals by the inflammasomes. Immunol. Rev. 243 (2011), 119–135.
    • (2011) Immunol. Rev. , vol.243 , pp. 119-135
    • Horvath, G.L.1    Schrum, J.E.2    De Nardo, C.M.3    Latz, E.4
  • 30
    • 77957554717 scopus 로고    scopus 로고
    • Molecular mechanism of NLRP3 inflammasome activation
    • Jin, C., Flavell, R.A., Molecular mechanism of NLRP3 inflammasome activation. J. Clin. Immunol. 30 (2010), 628–631.
    • (2010) J. Clin. Immunol. , vol.30 , pp. 628-631
    • Jin, C.1    Flavell, R.A.2
  • 31
    • 0030041184 scopus 로고    scopus 로고
    • Intestinal fatty acid binding protein is a useful diagnostic marker for mesenteric infarction in humans
    • Kanda, T., Fujii, H., Tani, T., Murakami, H., Suda, T., Sakai, Y., Ono, T., Hatakeyama, K., Intestinal fatty acid binding protein is a useful diagnostic marker for mesenteric infarction in humans. Gastroenterology 110 (1996), 339–343.
    • (1996) Gastroenterology , vol.110 , pp. 339-343
    • Kanda, T.1    Fujii, H.2    Tani, T.3    Murakami, H.4    Suda, T.5    Sakai, Y.6    Ono, T.7    Hatakeyama, K.8
  • 33
    • 25444474430 scopus 로고    scopus 로고
    • Modulatory effects of sCD14 and LBP on LPS-host cell interactions
    • Kitchens, R.L., Thompson, P.A., Modulatory effects of sCD14 and LBP on LPS-host cell interactions. J. Endotoxin Res. 11 (2005), 225–229.
    • (2005) J. Endotoxin Res. , vol.11 , pp. 225-229
    • Kitchens, R.L.1    Thompson, P.A.2
  • 34
    • 74549125391 scopus 로고    scopus 로고
    • The inflammasomes
    • Lamkanfi, M., Dixit, V.M., The inflammasomes. PLoS Pathog., 5, 2009, 10.1371/journal.ppat.1000510.
    • (2009) PLoS Pathog. , vol.5
    • Lamkanfi, M.1    Dixit, V.M.2
  • 35
    • 79952159132 scopus 로고    scopus 로고
    • Emerging inflammasome effector mechanisms
    • Lamkanfi, M., Emerging inflammasome effector mechanisms. Nat. Rev. Immunol. 11 (2011), 213–220.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 213-220
    • Lamkanfi, M.1
  • 36
    • 84901310586 scopus 로고    scopus 로고
    • Mechanisms and functions of inflammasomes
    • Lamkanfi, M., Dixit, V.M., Mechanisms and functions of inflammasomes. Cell 157 (2014), 1013–1022.
    • (2014) Cell , vol.157 , pp. 1013-1022
    • Lamkanfi, M.1    Dixit, V.M.2
  • 37
    • 0031048720 scopus 로고    scopus 로고
    • Human intestinal fatty acid binding protein: report of an assay with studies in normal volunteers and intestinal ischemia
    • Lieberman, J.M., Sacchettini, J., Marks, C., Marks, W.H., Human intestinal fatty acid binding protein: report of an assay with studies in normal volunteers and intestinal ischemia. Surgery 121 (1997), 335–342.
    • (1997) Surgery , vol.121 , pp. 335-342
    • Lieberman, J.M.1    Sacchettini, J.2    Marks, C.3    Marks, W.H.4
  • 40
    • 7944232105 scopus 로고    scopus 로고
    • Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
    • Martinon, F., Agostini, L., Meylan, E., Tschopp, J., Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14 (2004), 1929–1934.
    • (2004) Curr. Biol. , vol.14 , pp. 1929-1934
    • Martinon, F.1    Agostini, L.2    Meylan, E.3    Tschopp, J.4
  • 41
    • 2542457495 scopus 로고    scopus 로고
    • Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases
    • Martinon, F., Tschopp, J., Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117 (2004), 561–574.
    • (2004) Cell , vol.117 , pp. 561-574
    • Martinon, F.1    Tschopp, J.2
  • 42
    • 66749174867 scopus 로고    scopus 로고
    • The inflammasomes: guardians of the body
    • Martinon, F., Mayor, A., Tschopp, J., The inflammasomes: guardians of the body. Annu. Rev. Immunol. 27 (2009), 229–265.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 229-265
    • Martinon, F.1    Mayor, A.2    Tschopp, J.3
  • 43
    • 84926168759 scopus 로고    scopus 로고
    • Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis
    • Masi, A., Quintana, D.S., Hickie, I.B., Guastella, A.J., Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis. Mol. Psychiatry 20 (2015), 440–446.
    • (2015) Mol. Psychiatry , vol.20 , pp. 440-446
    • Masi, A.1    Quintana, D.S.2    Hickie, I.B.3    Guastella, A.J.4
  • 44
    • 84882285470 scopus 로고    scopus 로고
    • Specific inflammasomes in complex diseases
    • Master, S.L., Specific inflammasomes in complex diseases. Clin. Immunol. 143 (2013), 223–228.
    • (2013) Clin. Immunol. , vol.143 , pp. 223-228
    • Master, S.L.1
  • 45
    • 40449097257 scopus 로고    scopus 로고
    • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
    • Muruve, D.A., Petrilli, V., Zaiss, A.K., White, L.R., Clark, S.A., Ross, P.J., Parks, R.J., Tschopp, J., The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452 (2008), 103–107.
    • (2008) Nature , vol.452 , pp. 103-107
    • Muruve, D.A.1    Petrilli, V.2    Zaiss, A.K.3    White, L.R.4    Clark, S.A.5    Ross, P.J.6    Parks, R.J.7    Tschopp, J.8
  • 46
    • 84875690299 scopus 로고    scopus 로고
    • Requirements for innate immune pathways in environmentally induced autoimmunity
    • Pollard, K.M., Kono, D.H., Requirements for innate immune pathways in environmentally induced autoimmunity. BMC Med., 11, 2013, 100.
    • (2013) BMC Med. , vol.11 , pp. 100
    • Pollard, K.M.1    Kono, D.H.2
  • 47
    • 70449534695 scopus 로고    scopus 로고
    • CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?
    • Rezai-Zadeh, K., Gate, D., Town, T., CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?. J. Neuroimmune Pharmacol. 4 (2009), 462–475.
    • (2009) J. Neuroimmune Pharmacol. , vol.4 , pp. 462-475
    • Rezai-Zadeh, K.1    Gate, D.2    Town, T.3
  • 48
    • 84871280445 scopus 로고    scopus 로고
    • Evidence of microglial activation in autism and its possible role in brain underconnectivity
    • Rodriguez, J.I., Kern, J.K., Evidence of microglial activation in autism and its possible role in brain underconnectivity. Neuron Glia Biol. 7 (2011), 205–213.
    • (2011) Neuron Glia Biol. , vol.7 , pp. 205-213
    • Rodriguez, J.I.1    Kern, J.K.2
  • 49
    • 84868314921 scopus 로고    scopus 로고
    • Redox control of NLRP3 inflammasome activation in health and disease
    • Rubartelli, A., Redox control of NLRP3 inflammasome activation in health and disease. J. Leukoc. Biol. 92 (2012), 951–958.
    • (2012) J. Leukoc. Biol. , vol.92 , pp. 951-958
    • Rubartelli, A.1
  • 53
    • 77950362382 scopus 로고    scopus 로고
    • The inflammosomes
    • Schroder, K., Tschopp, J., The inflammosomes. Cell 140 (2010), 821–832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 54
    • 84901258066 scopus 로고    scopus 로고
    • Contribution of intestinal barrier damage, microbial translocation and HIV-1 infection status to an inflammaging signature
    • Steele, A.K., Lee, E.J., Vestal, B., Hecht, D., Dong, Z., Rapaport, E., Koeppe, J., Campbell, T.B., Wilson, C.C., Contribution of intestinal barrier damage, microbial translocation and HIV-1 infection status to an inflammaging signature. PLoS ONE, 9(5), 2014, e97171.
    • (2014) PLoS ONE , vol.9 , Issue.5 , pp. e97171
    • Steele, A.K.1    Lee, E.J.2    Vestal, B.3    Hecht, D.4    Dong, Z.5    Rapaport, E.6    Koeppe, J.7    Campbell, T.B.8    Wilson, C.C.9
  • 56
    • 11144230769 scopus 로고    scopus 로고
    • Neuroglial activation and neuroinflammation in the brain of patients with autism
    • Erratum in: Ann Neurol. 57, 304. PubMed PMID: 15546155
    • Vargas, D.L., Nascimbene, C., Krishnan, C., Zimmerman, A.W., Pardo, C.A., Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann. Neurol. 57 (2005), 67–81 Erratum in: Ann Neurol. 57, 304. PubMed PMID: 15546155.
    • (2005) Ann. Neurol. , vol.57 , pp. 67-81
    • Vargas, D.L.1    Nascimbene, C.2    Krishnan, C.3    Zimmerman, A.W.4    Pardo, C.A.5
  • 57
    • 84884332722 scopus 로고    scopus 로고
    • Mechanisms of NOD-like receptor-associated inflammasome activation
    • Wen, H., Miao, E.A., Ting, J.P., Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity 39 (2013), 432–441.
    • (2013) Immunity , vol.39 , pp. 432-441
    • Wen, H.1    Miao, E.A.2    Ting, J.P.3


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