메뉴 건너뛰기




Volumn 24, Issue 1, 2010, Pages 64-71

Differential monocyte responses to TLR ligands in children with autism spectrum disorders

Author keywords

ASD; Autism; Cytokines; Inflammation; Monocytes; Toll like receptors

Indexed keywords

FLAGELLIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIGAND; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

EID: 71749094505     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2009.08.001     Document Type: Article
Times cited : (227)

References (67)
  • 1
    • 33644643210 scopus 로고    scopus 로고
    • IL-1beta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy
    • Aly H., Khashaba M.T., El-Ayouty M., El-Sayed O., and Hasanein B.M. IL-1beta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy. Brain Dev. 28 (2006) 178-182
    • (2006) Brain Dev. , vol.28 , pp. 178-182
    • Aly, H.1    Khashaba, M.T.2    El-Ayouty, M.3    El-Sayed, O.4    Hasanein, B.M.5
  • 2
    • 62549100406 scopus 로고    scopus 로고
    • Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders
    • Ashwood P., Schauer J., Pessah I.N., and Van de Water J. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. J. Neuroimmunol. 208 (2009) 130-135
    • (2009) J. Neuroimmunol. , vol.208 , pp. 130-135
    • Ashwood, P.1    Schauer, J.2    Pessah, I.N.3    Van de Water, J.4
  • 3
    • 33644951883 scopus 로고    scopus 로고
    • Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms
    • Ashwood P., and Wakefield A.J. Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms. J. Neuroimmunol. 173 (2006) 126-134
    • (2006) J. Neuroimmunol. , vol.173 , pp. 126-134
    • Ashwood, P.1    Wakefield, A.J.2
  • 5
    • 0030669279 scopus 로고    scopus 로고
    • Neoexpression of the c-met/hepatocyte growth factor-scatter factor receptor gene in activated monocytes
    • Beilmann M., Odenthal M., Jung W., Vande Woude G.F., Dienes H.P., and Schirmacher P. Neoexpression of the c-met/hepatocyte growth factor-scatter factor receptor gene in activated monocytes. Blood 90 (1997) 4450-4458
    • (1997) Blood , vol.90 , pp. 4450-4458
    • Beilmann, M.1    Odenthal, M.2    Jung, W.3    Vande Woude, G.F.4    Dienes, H.P.5    Schirmacher, P.6
  • 6
    • 0034660624 scopus 로고    scopus 로고
    • Hepatocyte growth factor-stimulated invasiveness of monocytes
    • Beilmann M., Vande Woude G.F., Dienes H.P., and Schirmacher P. Hepatocyte growth factor-stimulated invasiveness of monocytes. Blood 95 (2000) 3964-3969
    • (2000) Blood , vol.95 , pp. 3964-3969
    • Beilmann, M.1    Vande Woude, G.F.2    Dienes, H.P.3    Schirmacher, P.4
  • 7
    • 0036150201 scopus 로고    scopus 로고
    • Prenatal immune challenge disrupts sensorimotor gating in adult rats. Implications for the etiopathogenesis of schizophrenia
    • Borrell J., Vela J.M., Arevalo-Martin A., Molina-Holgado E., and Guaza C. Prenatal immune challenge disrupts sensorimotor gating in adult rats. Implications for the etiopathogenesis of schizophrenia. Neuropsychopharmacology 26 (2002) 204-215
    • (2002) Neuropsychopharmacology , vol.26 , pp. 204-215
    • Borrell, J.1    Vela, J.M.2    Arevalo-Martin, A.3    Molina-Holgado, E.4    Guaza, C.5
  • 8
    • 0036841178 scopus 로고    scopus 로고
    • Broad expression of Toll-like receptors in the human central nervous system
    • Bsibsi M., Ravid R., Gveric D., and van Noort J.M. Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol. 61 (2002) 1013-1021
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 1013-1021
    • Bsibsi, M.1    Ravid, R.2    Gveric, D.3    van Noort, J.M.4
  • 9
    • 34648837683 scopus 로고    scopus 로고
    • Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder
    • Cabanlit M., Wills S., Goines P., Ashwood P., and Van de Water J. Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder. Ann. NY Acad. Sci. 1107 (2007) 92-103
    • (2007) Ann. NY Acad. Sci. , vol.1107 , pp. 92-103
    • Cabanlit, M.1    Wills, S.2    Goines, P.3    Ashwood, P.4    Van de Water, J.5
  • 12
    • 32544434349 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleffner syndrome, and epilepsy
    • Connolly A.M., Chez M., Streif E.M., Keeling R.M., Golumbek P.T., Kwon J.M., Riviello J.J., Robinson R.G., Neuman R.J., and Deuel R.M. Brain-derived neurotrophic factor and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleffner syndrome, and epilepsy. Biol. Psychiatry 59 (2006) 354-363
    • (2006) Biol. Psychiatry , vol.59 , pp. 354-363
    • Connolly, A.M.1    Chez, M.2    Streif, E.M.3    Keeling, R.M.4    Golumbek, P.T.5    Kwon, J.M.6    Riviello, J.J.7    Robinson, R.G.8    Neuman, R.J.9    Deuel, R.M.10
  • 13
    • 0033510928 scopus 로고    scopus 로고
    • Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders
    • Connolly A.M., Chez M.G., Pestronk A., Arnold S.T., Mehta S., and Deuel R.K. Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders. J. Pediatr. 134 (1999) 607-613
    • (1999) J. Pediatr. , vol.134 , pp. 607-613
    • Connolly, A.M.1    Chez, M.G.2    Pestronk, A.3    Arnold, S.T.4    Mehta, S.5    Deuel, R.K.6
  • 16
    • 0029928265 scopus 로고    scopus 로고
    • Lymphocyte subsets and interleukin-2 receptors in autistic children
    • Denney D.R., Frei B.W., and Gaffney G.R. Lymphocyte subsets and interleukin-2 receptors in autistic children. J. Autism Dev. Disord. 26 (1996) 87-97
    • (1996) J. Autism Dev. Disord. , vol.26 , pp. 87-97
    • Denney, D.R.1    Frei, B.W.2    Gaffney, G.R.3
  • 17
    • 33846704033 scopus 로고    scopus 로고
    • Developmental switch in the effects of TNFalpha on ventral midbrain dopaminergic neurons
    • Doherty G.H. Developmental switch in the effects of TNFalpha on ventral midbrain dopaminergic neurons. Neurosci. Res. 57 (2007) 296-305
    • (2007) Neurosci. Res. , vol.57 , pp. 296-305
    • Doherty, G.H.1
  • 18
    • 33746724668 scopus 로고    scopus 로고
    • Effects of cytokines and infections on brain neurochemistry
    • Dunn A.J. Effects of cytokines and infections on brain neurochemistry. Clin. Neurosci. Res. 6 (2006) 52-68
    • (2006) Clin. Neurosci. Res. , vol.6 , pp. 52-68
    • Dunn, A.J.1
  • 21
    • 34548823235 scopus 로고    scopus 로고
    • Innate immunity: toll-like receptors and some more. A brief history, basic organization and relevance for the human newborn
    • Fleer A., and Krediet T.G. Innate immunity: toll-like receptors and some more. A brief history, basic organization and relevance for the human newborn. Neonatology 92 (2007) 145-157
    • (2007) Neonatology , vol.92 , pp. 145-157
    • Fleer, A.1    Krediet, T.G.2
  • 22
    • 31144444162 scopus 로고    scopus 로고
    • Epidemiology of autistic disorder and other pervasive developmental disorders
    • Fombonne E. Epidemiology of autistic disorder and other pervasive developmental disorders. J. Clin. Psychiatry 66 Suppl. 10 (2005) 3-8
    • (2005) J. Clin. Psychiatry , vol.66 , Issue.SUPPL. 10 , pp. 3-8
    • Fombonne, E.1
  • 23
    • 34250196472 scopus 로고    scopus 로고
    • Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy
    • Fortier M.E., Luheshi G.N., and Boksa P. Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy. Behav. Brain Res. 181 (2007) 270-277
    • (2007) Behav. Brain Res. , vol.181 , pp. 270-277
    • Fortier, M.E.1    Luheshi, G.N.2    Boksa, P.3
  • 25
    • 12344280393 scopus 로고    scopus 로고
    • Maternal poly I:C exposure during pregnancy regulates TNF alpha, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat
    • Gilmore J.H., Jarskog L.F., and Vadlamudi S. Maternal poly I:C exposure during pregnancy regulates TNF alpha, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat. J. Neuroimmunol. 159 (2005) 106-112
    • (2005) J. Neuroimmunol. , vol.159 , pp. 106-112
    • Gilmore, J.H.1    Jarskog, L.F.2    Vadlamudi, S.3
  • 28
    • 0032078663 scopus 로고    scopus 로고
    • Th1- and Th2-like cytokines in CD4+ and CD8+ T cells in autism
    • Gupta S., Aggarwal S., Rashanravan B., and Lee T. Th1- and Th2-like cytokines in CD4+ and CD8+ T cells in autism. J. Neuroimmunol. 85 (1998) 106-109
    • (1998) J. Neuroimmunol. , vol.85 , pp. 106-109
    • Gupta, S.1    Aggarwal, S.2    Rashanravan, B.3    Lee, T.4
  • 29
    • 33645107794 scopus 로고    scopus 로고
    • Alterations in behavior in adult offspring mice following maternal inflammation during pregnancy
    • Hava G., Vered L., Yael M., Mordechai H., and Mahoud H. Alterations in behavior in adult offspring mice following maternal inflammation during pregnancy. Dev. Psychobiol. 48 (2006) 162-168
    • (2006) Dev. Psychobiol. , vol.48 , pp. 162-168
    • Hava, G.1    Vered, L.2    Yael, M.3    Mordechai, H.4    Mahoud, H.5
  • 33
    • 27944464966 scopus 로고    scopus 로고
    • Mucosal repair and growth factors: recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease
    • Ido A., Numata M., Kodama M., and Tsubouchi H. Mucosal repair and growth factors: recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease. J. Gastroenterol. 40 (2005) 925-931
    • (2005) J. Gastroenterol. , vol.40 , pp. 925-931
    • Ido, A.1    Numata, M.2    Kodama, M.3    Tsubouchi, H.4
  • 34
    • 17144419260 scopus 로고    scopus 로고
    • Dysregulated innate immune responses in young children with autism spectrum disorders: their relationship to gastrointestinal symptoms and dietary intervention
    • Jyonouchi H., Geng L., Ruby A., and Zimmerman-Bier B. Dysregulated innate immune responses in young children with autism spectrum disorders: their relationship to gastrointestinal symptoms and dietary intervention. Neuropsychobiology 51 (2005) 77-85
    • (2005) Neuropsychobiology , vol.51 , pp. 77-85
    • Jyonouchi, H.1    Geng, L.2    Ruby, A.3    Zimmerman-Bier, B.4
  • 35
    • 0036970874 scopus 로고    scopus 로고
    • Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder
    • Jyonouchi H., Sun S., and Itokazu N. Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. Neuropsychobiology 46 (2002) 76-84
    • (2002) Neuropsychobiology , vol.46 , pp. 76-84
    • Jyonouchi, H.1    Sun, S.2    Itokazu, N.3
  • 36
    • 0034750434 scopus 로고    scopus 로고
    • Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression
    • Jyonouchi H., Sun S., and Le H. Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression. J. Neuroimmunol. 120 (2001) 170-179
    • (2001) J. Neuroimmunol. , vol.120 , pp. 170-179
    • Jyonouchi, H.1    Sun, S.2    Le, H.3
  • 38
    • 14844348476 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia
    • Kielian T., Esen N., and Bearden E.D. Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia. Glia 49 (2005) 567-576
    • (2005) Glia , vol.49 , pp. 567-576
    • Kielian, T.1    Esen, N.2    Bearden, E.D.3
  • 42
    • 36949028725 scopus 로고    scopus 로고
    • Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge
    • Meyer U., Nyffeler M., Schwendener S., Knuesel I., Yee B.K., and Feldon J. Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge. Neuropsychopharmacology 33 (2007) 441-456
    • (2007) Neuropsychopharmacology , vol.33 , pp. 441-456
    • Meyer, U.1    Nyffeler, M.2    Schwendener, S.3    Knuesel, I.4    Yee, B.K.5    Feldon, J.6
  • 46
    • 4644232615 scopus 로고    scopus 로고
    • Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
    • Olson J.K., and Miller S.D. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J. Immunol. 173 (2004) 3916-3924
    • (2004) J. Immunol. , vol.173 , pp. 3916-3924
    • Olson, J.K.1    Miller, S.D.2
  • 48
    • 33846913527 scopus 로고    scopus 로고
    • Infection in the first 2 years of life and autism spectrum disorders
    • Rosen N.J., Yoshida C.K., and Croen L.A. Infection in the first 2 years of life and autism spectrum disorders. Pediatrics 119 (2007) 61-69
    • (2007) Pediatrics , vol.119 , pp. 61-69
    • Rosen, N.J.1    Yoshida, C.K.2    Croen, L.A.3
  • 53
    • 4444225180 scopus 로고    scopus 로고
    • Detection of antinuclear and antilaminin antibodies in autistic children who received thimerosal-containing vaccines
    • Singh V.K., and Rivas W.H. Detection of antinuclear and antilaminin antibodies in autistic children who received thimerosal-containing vaccines. J. Biomed. Sci. 11 (2004) 607-610
    • (2004) J. Biomed. Sci. , vol.11 , pp. 607-610
    • Singh, V.K.1    Rivas, W.H.2
  • 54
    • 0347914616 scopus 로고    scopus 로고
    • Prevalence of serum antibodies to caudate nucleus in autistic children
    • Singh V.K., and Rivas W.H. Prevalence of serum antibodies to caudate nucleus in autistic children. Neurosci. Lett. 355 (2004) 53-56
    • (2004) Neurosci. Lett. , vol.355 , pp. 53-56
    • Singh, V.K.1    Rivas, W.H.2
  • 55
    • 0030990508 scopus 로고    scopus 로고
    • Hyperserotoninemia and serotonin receptor antibodies in children with autism but not mental retardation
    • Singh V.K., Singh E.A., and Warren R.P. Hyperserotoninemia and serotonin receptor antibodies in children with autism but not mental retardation. Biol. Psychiatry 41 (1997) 753-755
    • (1997) Biol. Psychiatry , vol.41 , pp. 753-755
    • Singh, V.K.1    Singh, E.A.2    Warren, R.P.3
  • 56
    • 0030886961 scopus 로고    scopus 로고
    • Circulating autoantibodies to neuronal and glial filament proteins in autism
    • Singh V.K., Warren R., Averett R., and Ghaziuddin M. Circulating autoantibodies to neuronal and glial filament proteins in autism. Pediatr. Neurol. 17 (1997) 88-90
    • (1997) Pediatr. Neurol. , vol.17 , pp. 88-90
    • Singh, V.K.1    Warren, R.2    Averett, R.3    Ghaziuddin, M.4
  • 57
    • 0026353152 scopus 로고
    • Changes of soluble interleukin-2, interleukin-2 receptor, T8 antigen, and interleukin-1 in the serum of autistic children
    • Singh V.K., Warren R.P., Odell J.D., and Cole P. Changes of soluble interleukin-2, interleukin-2 receptor, T8 antigen, and interleukin-1 in the serum of autistic children. Clin. Immunol. Immunopathol. 61 (1991) 448-455
    • (1991) Clin. Immunol. Immunopathol. , vol.61 , pp. 448-455
    • Singh, V.K.1    Warren, R.P.2    Odell, J.D.3    Cole, P.4
  • 59
    • 35148872226 scopus 로고    scopus 로고
    • Maternal immune activation alters fetal brain development through interleukin-6
    • Smith S.E., Li J., Garbett K., Mirnics K., and Patterson P.H. Maternal immune activation alters fetal brain development through interleukin-6. J. Neurosci. 27 (2007) 10695-10702
    • (2007) J. Neurosci. , vol.27 , pp. 10695-10702
    • Smith, S.E.1    Li, J.2    Garbett, K.3    Mirnics, K.4    Patterson, P.H.5
  • 60
    • 0642343891 scopus 로고    scopus 로고
    • High blood monocyte counts and neopterin levels in children with autistic disorder
    • Sweeten T.L., Posey D.J., and McDougle C.J. High blood monocyte counts and neopterin levels in children with autistic disorder. Am. J. Psychiatry 160 (2003) 1691-1693
    • (2003) Am. J. Psychiatry , vol.160 , pp. 1691-1693
    • Sweeten, T.L.1    Posey, D.J.2    McDougle, C.J.3
  • 63
    • 11144230769 scopus 로고    scopus 로고
    • Neuroglial activation and neuroinflammation in the brain of patients with autism
    • Vargas D.L., Nascimbene C., Krishnan C., Zimmerman A.W., and Pardo C.A. Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann. Neurol. 57 (2005) 67-81
    • (2005) Ann. Neurol. , vol.57 , pp. 67-81
    • Vargas, D.L.1    Nascimbene, C.2    Krishnan, C.3    Zimmerman, A.W.4    Pardo, C.A.5
  • 66
    • 56949085021 scopus 로고    scopus 로고
    • Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders
    • Wills S., Cabanlit M., Bennett J., Ashwood P., Amaral D.G., and Van de Water J. Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders. Brain Behav. Immun. 23 (2009) 64-74
    • (2009) Brain Behav. Immun. , vol.23 , pp. 64-74
    • Wills, S.1    Cabanlit, M.2    Bennett, J.3    Ashwood, P.4    Amaral, D.G.5    Van de Water, J.6
  • 67
    • 0036019158 scopus 로고    scopus 로고
    • The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll-like receptor 2 and CD14 in the mouse CNS
    • Zekki H., Feinstein D.L., and Rivest S. The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll-like receptor 2 and CD14 in the mouse CNS. Brain Pathol. 12 (2002) 308-319
    • (2002) Brain Pathol. , vol.12 , pp. 308-319
    • Zekki, H.1    Feinstein, D.L.2    Rivest, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.