An Autistic Endophenotype Results in Complex Immune Dysfunction in Healthy Siblings of Autistic Children

Biological Psychiatry

Volumn 66, Issue 10, 2009, Pages 978-984

  Saresella, Marina ^a   Marventano, Ivana ^a   Guerini, Franca Rosa ^a   Mancuso, Roberta ^a   Ceresa, Lara ^a   Zanzottera, Milena ^a   Rusconi, Beatrice ^b   Maggioni, Emanuela ^a   Tinelli, Carmine ^c   Clerici, Mario ^a,b  

^a Don C Gnocchi ONLUS Foundation IRCCS SM Nascente   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Autism; autistic endophenotype; cytokines; immunology; T lymphocytes; thymus

Indexed keywords

AUTOANTIBODY; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON; GANGLIOSIDE GM1 ANTIBODY; GRANZYME; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; AGE DISTRIBUTION; ANTIBODY BLOOD LEVEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOPATHOLOGY; IMMUNOPHENOTYPING; INFANTILE AUTISM; INFLAMMATORY CELL; LYMPHOCYTE DIFFERENTIATION; MAJOR CLINICAL STUDY; MALE; MEMORY CELL; PILOT STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEX RATIO; SIBLING;

ADOLESCENT; ANTIGEN-ANTIBODY COMPLEX; AUTISTIC DISORDER; AUTOANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRANZYMES; HUMANS; IMMUNE SYSTEM DISEASES; MALE; PERFORIN; SIBLINGS; VIRAL PROTEINS;

EID: 70350575737     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2009.06.020     Document Type: Article

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