메뉴 건너뛰기




Volumn 17, Issue 5, 2016, Pages 556-564

Phosphatase PP2A is requisite for the function of regulatory T cells

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATASE; PHOSPHATASE PP2A; UNCLASSIFIED DRUG; CERAMIDE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PHOSPHOPROTEIN PHOSPHATASE 2; TARGET OF RAPAMYCIN KINASE;

EID: 84961226881     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3390     Document Type: Article
Times cited : (192)

References (55)
  • 2
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: Mechanisms of differentiation and function
    • Josefowicz, S.Z., Lu, L.F., Rudensky, A.Y. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30, 531-564 (2012).
    • (2012) Annu. Rev. Immunol , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.F.2    Rudensky, A.Y.3
  • 3
    • 84860237060 scopus 로고    scopus 로고
    • Regulation and function of mTOR signalling in T cell fate decisions
    • Chi, H. Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 12, 325-338 (2012).
    • (2012) Nat. Rev. Immunol , vol.12 , pp. 325-338
    • Chi, H.1
  • 4
    • 0025317650 scopus 로고
    • The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
    • Lyon, M.F., Peters, J., Glenister, P.H., Ball, S., Wright, E. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome. Proc. Natl. Acad. Sci. USA 87, 2433-2437 (1990).
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2433-2437
    • Lyon, M.F.1    Peters, J.2    Glenister, P.H.3    Ball, S.4    Wright, E.5
  • 5
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett, C.L. et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27, 20-21 (2001).
    • (2001) Nat. Genet , vol.27 , pp. 20-21
    • Bennett, C.L.1
  • 6
    • 33845404441 scopus 로고    scopus 로고
    • Structure of the protein phosphatase 2A holoenzyme
    • Xu, Y. et al. Structure of the protein phosphatase 2A holoenzyme. Cell 127, 1239-1251 (2006).
    • (2006) Cell , vol.127 , pp. 1239-1251
    • Xu, Y.1
  • 7
    • 70350340056 scopus 로고    scopus 로고
    • Serine/threonine phosphatases: Mechanism through structure
    • Shi, Y. Serine/threonine phosphatases: mechanism through structure. Cell 139, 468-484 (2009).
    • (2009) Cell , vol.139 , pp. 468-484
    • Shi, Y.1
  • 8
    • 34447106751 scopus 로고    scopus 로고
    • PP2A: Unveiling a reluctant tumor suppressor
    • Mumby, M. PP2A: unveiling a reluctant tumor suppressor. Cell 130, 21-24 (2007).
    • (2007) Cell , vol.130 , pp. 21-24
    • Mumby, M.1
  • 9
    • 84897401611 scopus 로고    scopus 로고
    • Protein phosphatase 2A dysfunction in Alzheimer's disease
    • Sontag, J.M., Sontag, E. Protein phosphatase 2A dysfunction in Alzheimer's disease. Front. Mol. Neurosci. 7, 16 (2014).
    • (2014) Front. Mol. Neurosci , vol.7 , pp. 16
    • Sontag, J.M.1    Sontag, E.2
  • 10
    • 82555196095 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Tsokos, G.C. Systemic lupus erythematosus. N. Engl. J. Med. 365, 2110-2121 (2011).
    • (2011) N. Engl. J. Med , vol.365 , pp. 2110-2121
    • Tsokos, G.C.1
  • 11
    • 27644546349 scopus 로고    scopus 로고
    • Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus
    • Katsiari, C.G., Kyttaris, V.C., Juang, Y.T., Tsokos, G.C. Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus. J. Clin. Invest. 115, 3193-3204 (2005).
    • (2005) J. Clin. Invest , vol.115 , pp. 3193-3204
    • Katsiari, C.G.1    Kyttaris, V.C.2    Juang, Y.T.3    Tsokos, G.C.4
  • 12
    • 84875809876 scopus 로고    scopus 로고
    • Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance
    • Xie, L. et al. Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Rep. 3, 678-688 (2013).
    • (2013) Cell Rep , vol.3 , pp. 678-688
    • Xie, L.1
  • 13
    • 84893604594 scopus 로고    scopus 로고
    • In vivo discovery of immunotherapy targets in the tumour microenvironment
    • Zhou, P. et al. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature 506, 52-57 (2014).
    • (2014) Nature , vol.506 , pp. 52-57
    • Zhou, P.1
  • 14
    • 84899125841 scopus 로고    scopus 로고
    • Recruitment of phosphatase PP2A by RACK1 adaptor protein deactivates transcription factor IRF3 and limits type i interferon signaling
    • Long, L. et al. Recruitment of phosphatase PP2A by RACK1 adaptor protein deactivates transcription factor IRF3 and limits type I interferon signaling. Immunity 40, 515-529 (2014).
    • (2014) Immunity , vol.40 , pp. 515-529
    • Long, L.1
  • 16
    • 84908123494 scopus 로고    scopus 로고
    • Continuous requirement for the TCR in regulatory T cell function
    • Levine, A.G., Arvey, A., Jin, W., Rudensky, A.Y. Continuous requirement for the TCR in regulatory T cell function. Nat. Immunol. 15, 1070-1078 (2014).
    • (2014) Nat. Immunol , vol.15 , pp. 1070-1078
    • Levine, A.G.1    Arvey, A.2    Jin, W.3    Rudensky, A.Y.4
  • 17
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon, B. et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12, 431-440 (2000).
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1
  • 18
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot, J.D., Rasmussen, J.P., Gavin, M.A., Rudensky, A.Y. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6, 1142-1151 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 19
    • 15444374646 scopus 로고    scopus 로고
    • Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • Setoguchi, R., Hori, S., Takahashi, T., Sakaguchi, S. Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 201, 723-735 (2005).
    • (2005) J. Exp. Med , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 20
    • 79952985551 scopus 로고    scopus 로고
    • The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
    • Delgoffe, G.M. et al. The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat. Immunol. 12, 295-303 (2011).
    • (2011) Nat. Immunol , vol.12 , pp. 295-303
    • Delgoffe, G.M.1
  • 21
    • 41149113441 scopus 로고    scopus 로고
    • The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
    • Haxhinasto, S., Mathis, D., Benoist, C. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J. Exp. Med. 205, 565-574 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 565-574
    • Haxhinasto, S.1    Mathis, D.2    Benoist, C.3
  • 22
    • 84922930171 scopus 로고    scopus 로고
    • Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses
    • Shrestha, S. et al. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat. Immunol. 16, 178-187 (2015).
    • (2015) Nat. Immunol , vol.16 , pp. 178-187
    • Shrestha, S.1
  • 23
    • 84884206864 scopus 로고    scopus 로고
    • Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis
    • Delgoffe, G.M. et al. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature 501, 252-256 (2013).
    • (2013) Nature , vol.501 , pp. 252-256
    • Delgoffe, G.M.1
  • 24
    • 34250356465 scopus 로고    scopus 로고
    • Generation of active protein phosphatase 2A is coupled to holoenzyme assembly
    • Hombauer, H. et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol. 5, e155 (2007).
    • (2007) PLoS Biol , vol.5 , pp. e155
    • Hombauer, H.1
  • 25
    • 84872761033 scopus 로고    scopus 로고
    • The biogenesis of active protein phosphatase 2A holoenzymes: A tightly regulated process creating phosphatase specificity
    • Sents, W., Ivanova, E., Lambrecht, C., Haesen, D., Janssens, V. The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity. FEBS J. 280, 644-661 (2013).
    • (2013) FEBS J , vol.280 , pp. 644-661
    • Sents, W.1    Ivanova, E.2    Lambrecht, C.3    Haesen, D.4    Janssens, V.5
  • 26
    • 84877727703 scopus 로고    scopus 로고
    • Structural basis of protein phosphatase 2A stable latency
    • Jiang, L. et al. Structural basis of protein phosphatase 2A stable latency. Nat. Commun. 4, 1699 (2013).
    • (2013) Nat. Commun , vol.4 , pp. 1699
    • Jiang, L.1
  • 27
    • 84915763090 scopus 로고    scopus 로고
    • The basic biology of PP2A in hematologic cells and malignancies
    • Haesen, D., Sents, W., Lemaire, K., Hoorne, Y., Janssens, V. The basic biology of PP2A in hematologic cells and malignancies. Front. Oncol. 4, 347 (2014).
    • (2014) Front. Oncol , vol.4 , pp. 347
    • Haesen, D.1    Sents, W.2    Lemaire, K.3    Hoorne, Y.4    Janssens, V.5
  • 28
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow, M.E. et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27, 68-73 (2001).
    • (2001) Nat. Genet , vol.27 , pp. 68-73
    • Brunkow, M.E.1
  • 29
    • 0032563209 scopus 로고    scopus 로고
    • Autoregulation of protein phosphatase type 2A expression
    • Baharians, Z., Schönthal, A.H. Autoregulation of protein phosphatase type 2A expression. J. Biol. Chem. 273, 19019-19024 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 19019-19024
    • Baharians, Z.1    Schönthal, A.H.2
  • 30
    • 39949083195 scopus 로고    scopus 로고
    • PP2A holoenzyme assembly: In cauda venenum (the sting is in the tail)
    • Janssens, V., Longin, S., Goris, J. PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail). Trends Biochem. Sci. 33, 113-121 (2008).
    • (2008) Trends Biochem. Sci , vol.33 , pp. 113-121
    • Janssens, V.1    Longin, S.2    Goris, J.3
  • 31
    • 0026786471 scopus 로고
    • Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation
    • Chen, J., Martin, B.L., Brautigan, D.L. Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation. Science 257, 1261-1264 (1992).
    • (1992) Science , vol.257 , pp. 1261-1264
    • Chen, J.1    Martin, B.L.2    Brautigan, D.L.3
  • 32
    • 27644569730 scopus 로고    scopus 로고
    • The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
    • Neviani, P. et al. The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Cancer Cell 8, 355-368 (2005).
    • (2005) Cancer Cell , vol.8 , pp. 355-368
    • Neviani, P.1
  • 33
    • 34948812373 scopus 로고    scopus 로고
    • The PP2A inhibitor SET regulates natural killer cell IFN-γ production
    • Trotta, R. et al. The PP2A inhibitor SET regulates natural killer cell IFN-γ production. J. Exp. Med. 204, 2397-2405 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 2397-2405
    • Trotta, R.1
  • 34
    • 0029889342 scopus 로고    scopus 로고
    • The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A
    • Li, M., Makkinje, A., Damuni, Z. The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A. J. Biol. Chem. 271, 11059-11062 (1996).
    • (1996) J. Biol. Chem , vol.271 , pp. 11059-11062
    • Li, M.1    Makkinje, A.2    Damuni, Z.3
  • 35
  • 36
    • 85021722110 scopus 로고    scopus 로고
    • Regulation of PP2A by sphingolipid metabolism and signaling
    • Oaks, J., Ogretmen, B. Regulation of PP2A by sphingolipid metabolism and signaling. Front. Oncol. 4, 388 (2014).
    • (2014) Front. Oncol , vol.4 , pp. 388
    • Oaks, J.1    Ogretmen, B.2
  • 37
    • 61549109860 scopus 로고    scopus 로고
    • Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
    • Mukhopadhyay, A. et al. Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling. FASEB J. 23, 751-763 (2009).
    • (2009) FASEB J , vol.23 , pp. 751-763
    • Mukhopadhyay, A.1
  • 38
    • 67649170980 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells: Differentiation, specification, subphenotypes
    • Feuerer, M., Hill, J.A., Mathis, D., Benoist, C. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat. Immunol. 10, 689-695 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 689-695
    • Feuerer, M.1    Hill, J.A.2    Mathis, D.3    Benoist, C.4
  • 39
    • 0032486257 scopus 로고    scopus 로고
    • Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?
    • Luberto, C., Hannun, Y.A. Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J. Biol. Chem. 273, 14550-14559 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 14550-14559
    • Luberto, C.1    Hannun, Y.A.2
  • 40
    • 34248216667 scopus 로고    scopus 로고
    • Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage
    • Separovic, D. et al. Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage. Biochem. Biophys. Res. Commun. 358, 196-202 (2007).
    • (2007) Biochem. Biophys. Res. Commun , vol.358 , pp. 196-202
    • Separovic, D.1
  • 41
    • 84901233628 scopus 로고    scopus 로고
    • Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells
    • Arvey, A. et al. Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells. Nat. Immunol. 15, 580-587 (2014).
    • (2014) Nat. Immunol , vol.15 , pp. 580-587
    • Arvey, A.1
  • 42
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante, M., Sabatini, D.M. mTOR signaling in growth control and disease. Cell 149, 274-293 (2012).
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 43
    • 84881192927 scopus 로고    scopus 로고
    • MTORC1 couples immune signals and metabolic programming to establish Treg-cell function
    • Zeng, H. et al. mTORC1 couples immune signals and metabolic programming to establish Treg-cell function. Nature 499, 485-490 (2013).
    • (2013) Nature , vol.499 , pp. 485-490
    • Zeng, H.1
  • 44
    • 79952235006 scopus 로고    scopus 로고
    • Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation
    • Marin, T.M. et al. Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation. J. Clin. Invest. 121, 1026-1043 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 1026-1043
    • Marin, T.M.1
  • 45
    • 77958151145 scopus 로고    scopus 로고
    • The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells
    • Liu, G., Yang, K., Burns, S., Shrestha, S., Chi, H. The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells. Nat. Immunol. 11, 1047-1056 (2010).
    • (2010) Nat. Immunol , vol.11 , pp. 1047-1056
    • Liu, G.1    Yang, K.2    Burns, S.3    Shrestha, S.4    Chi, H.5
  • 46
    • 20444373376 scopus 로고    scopus 로고
    • Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
    • Battaglia, M., Stabilini, A., Roncarolo, M.G. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood 105, 4743-4748 (2005).
    • (2005) Blood , vol.105 , pp. 4743-4748
    • Battaglia, M.1    Stabilini, A.2    Roncarolo, M.G.3
  • 47
    • 84866975037 scopus 로고    scopus 로고
    • Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
    • Samstein, R.M. et al. Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification. Cell 151, 153-166 (2012).
    • (2012) Cell , vol.151 , pp. 153-166
    • Samstein, R.M.1
  • 48
    • 84901936622 scopus 로고    scopus 로고
    • Sphingolipid metabolites in inflammatory disease
    • Maceyka, M., Spiegel, S. Sphingolipid metabolites in inflammatory disease. Nature 510, 58-67 (2014).
    • (2014) Nature , vol.510 , pp. 58-67
    • MacEyka, M.1    Spiegel, S.2
  • 49
    • 0029942186 scopus 로고    scopus 로고
    • Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
    • Andjelković, M. et al. Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc. Natl. Acad. Sci. USA 93, 5699-5704 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5699-5704
    • Andjelković, M.1
  • 50
    • 84922917657 scopus 로고    scopus 로고
    • Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
    • Huynh, A. et al. Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability. Nat. Immunol. 16, 188-196 (2015).
    • (2015) Nat. Immunol , vol.16 , pp. 188-196
    • Huynh, A.1
  • 51
    • 80052590060 scopus 로고    scopus 로고
    • Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice
    • Ruediger, R., Ruiz, J., Walter, G. Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice. Mol. Cell. Biol. 31, 3832-3844 (2011).
    • (2011) Mol. Cell. Biol , vol.31 , pp. 3832-3844
    • Ruediger, R.1    Ruiz, J.2    Walter, G.3
  • 52
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov, Y.P. et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28, 546-558 (2008).
    • (2008) Immunity , vol.28 , pp. 546-558
    • Rubtsov, Y.P.1
  • 53
    • 74949097878 scopus 로고    scopus 로고
    • Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
    • Bielawski, J. et al. Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods Mol. Biol. 579, 443-467 (2009).
    • (2009) Methods Mol. Biol , vol.579 , pp. 443-467
    • Bielawski, J.1
  • 55
    • 33746228122 scopus 로고    scopus 로고
    • FOXP3 controls regulatory T cell function through cooperation with NFAT
    • Wu, Y. et al. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 126, 375-387 (2006).
    • (2006) Cell , vol.126 , pp. 375-387
    • Wu, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.