메뉴 건너뛰기




Volumn 8, Issue 2, 2016, Pages 366-381

Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase

Author keywords

Cyclin dependent kinases; Hutchinson Gilford progeria syndrome; Lamin A; Liquid droplets; Senescence

Indexed keywords

LAMIN A; SERINE;

EID: 84961214787     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100903     Document Type: Article
Times cited : (18)

References (47)
  • 2
    • 33745904741 scopus 로고    scopus 로고
    • Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome
    • Dahl KN, Scaffidi P, Islam MF, Yodh AG, Wilson KL, Misteli T Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2006; 103: 10271-10276.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10271-10276
    • Dahl, K.N.1    Scaffidi, P.2    Islam, M.F.3    Yodh, A.G.4    Wilson, K.L.5    Misteli, T.6
  • 4
    • 0842347426 scopus 로고    scopus 로고
    • Expression of a mutant lamin A that causes Emery-Dreifuss muscular dystrophy inhibits in vitro differentiation of C2C12 myoblasts
    • Favreau C, Higuet D, Courvalin JC, Buendia B Expression of a mutant lamin A that causes Emery-Dreifuss muscular dystrophy inhibits in vitro differentiation of C2C12 myoblasts. Mol Cell Biol. 2004; 24: 1481-1492.
    • (2004) Mol Cell Biol , vol.24 , pp. 1481-1492
    • Favreau, C.1    Higuet, D.2    Courvalin, J.C.3    Buendia, B.4
  • 5
    • 0028923173 scopus 로고
    • Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells
    • Hozak P, Sasseville AM, Raymond Y, Cook PR Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells. J Cell Sci. 1995; 108: 635-644.
    • (1995) J Cell Sci , vol.108 , pp. 635-644
    • Hozak, P.1    Sasseville, A.M.2    Raymond, Y.3    Cook, P.R.4
  • 7
    • 76149084859 scopus 로고    scopus 로고
    • Role of A-type lamins in signaling, transcription, and chromatin organization
    • Andres V, Gonzalez JM Role of A-type lamins in signaling, transcription, and chromatin organization. J Cell Biol. 2009; 187: 945-957.
    • (2009) J Cell Biol , vol.187 , pp. 945-957
    • Andres, V.1    Gonzalez, J.M.2
  • 9
    • 0031686054 scopus 로고    scopus 로고
    • Nuclear lamins: their structure, assembly, and interactions
    • Stuurman N, Heins S, Aebi U Nuclear lamins: their structure, assembly, and interactions. J Struct Biol. 1998; 122: 42-66.
    • (1998) J Struct Biol , vol.122 , pp. 42-66
    • Stuurman, N.1    Heins, S.2    Aebi, U.3
  • 10
    • 0038319891 scopus 로고
    • Isolation of nuclear pore complexes in association with a lamina
    • Aaronson RP, Blobel G Isolation of nuclear pore complexes in association with a lamina. Proc Natl Acad Sci U S A. 1975; 72: 1007-1011.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 1007-1011
    • Aaronson, R.P.1    Blobel, G.2
  • 12
    • 0025876766 scopus 로고
    • Expression in Escherichia coli of human lamins A and C: influence of head and tail domains on assembly properties and paracrystal formation
    • Moir RD, Donaldson AD, Stewart M Expression in Escherichia coli of human lamins A and C: influence of head and tail domains on assembly properties and paracrystal formation. J Cell Sci. 1991; 99: 363-372.
    • (1991) J Cell Sci , vol.99 , pp. 363-372
    • Moir, R.D.1    Donaldson, A.D.2    Stewart, M.3
  • 13
    • 0033636843 scopus 로고    scopus 로고
    • Head and/or CaaX domain deletions of lamin proteins disrupt preformed lamin A and C but not lamin B structure in mammalian cells
    • Izumi M, Vaughan OA, Hutchison CJ, Gilbert DM Head and/or CaaX domain deletions of lamin proteins disrupt preformed lamin A and C but not lamin B structure in mammalian cells. Mol Biol Cell. 2000; 11: 4323-4337.
    • (2000) Mol Biol Cell , vol.11 , pp. 4323-4337
    • Izumi, M.1    Vaughan, O.A.2    Hutchison, C.J.3    Gilbert, D.M.4
  • 14
    • 0025352896 scopus 로고
    • Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis
    • Heald R, McKeon F Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis. Cell. 1990; 61: 579-589.
    • (1990) Cell , vol.61 , pp. 579-589
    • Heald, R.1    McKeon, F.2
  • 15
    • 0025736038 scopus 로고
    • Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase
    • Peter M, Heitlinger E, Haner M, Aebi U, Nigg EA Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase. EMBO J. 1991; 10: 1535-1544.
    • (1991) EMBO J , vol.10 , pp. 1535-1544
    • Peter, M.1    Heitlinger, E.2    Haner, M.3    Aebi, U.4    Nigg, E.A.5
  • 17
    • 59449102799 scopus 로고    scopus 로고
    • Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartment
    • Barrowman J, Hamblet C, George CM, Michaelis S Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartment. Mol Biol Cell. 2008; 19: 5398-5408.
    • (2008) Mol Biol Cell , vol.19 , pp. 5398-5408
    • Barrowman, J.1    Hamblet, C.2    George, C.M.3    Michaelis, S.4
  • 18
    • 33845269544 scopus 로고    scopus 로고
    • Hutchinson-Gilford progeria syndrome: review of the phenotype
    • Hennekam RC Hutchinson-Gilford progeria syndrome: review of the phenotype. Am J Med Genet A. 2006; 140: 2603-2624.
    • (2006) Am J Med Genet A , vol.140 , pp. 2603-2624
    • Hennekam, R.C.1
  • 24
    • 0028831126 scopus 로고
    • precursor is localized to intranuclear foci
    • Sasseville AM, Raymond Y Lamin A precursor is localized to intranuclear foci. J Cell Sci. 1995; 108: 273-285.
    • (1995) J Cell Sci , vol.108 , pp. 273-285
    • Sasseville, A.M.1    Raymond, Y.2    Lamin, A.3
  • 25
    • 14944383792 scopus 로고    scopus 로고
    • RNAi of FACE1 protease results in growth inhibition of human cells expressing lamin A: implications for Hutchinson-Gilford progeria syndrome
    • Gruber J, Lampe T, Osborn M, Weber K RNAi of FACE1 protease results in growth inhibition of human cells expressing lamin A: implications for Hutchinson-Gilford progeria syndrome. J Cell Sci. 2005; 118: 689-696.
    • (2005) J Cell Sci , vol.118 , pp. 689-696
    • Gruber, J.1    Lampe, T.2    Osborn, M.3    Weber, K.4
  • 26
    • 30044431691 scopus 로고    scopus 로고
    • K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes
    • Silvius JR, Bhagatji P, Leventis R, Terrone D K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes. Mol Biol Cell. 2006; 17: 192-202.
    • (2006) Mol Biol Cell , vol.17 , pp. 192-202
    • Silvius, J.R.1    Bhagatji, P.2    Leventis, R.3    Terrone, D.4
  • 30
    • 33947727395 scopus 로고    scopus 로고
    • Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex
    • Patel SS, Belmont BJ, Sante JM, Rexach MF Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell. 2007; 129: 83-96.
    • (2007) Cell , vol.129 , pp. 83-96
    • Patel, S.S.1    Belmont, B.J.2    Sante, J.M.3    Rexach, M.F.4
  • 31
    • 0029665778 scopus 로고    scopus 로고
    • Flavopiridol induces G1 arrest with inhibition of cyclindependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells
    • Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ Flavopiridol induces G1 arrest with inhibition of cyclindependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res. 1996; 56: 2973-2978.
    • (1996) Cancer Res , vol.56 , pp. 2973-2978
    • Carlson, B.A.1    Dubay, M.M.2    Sausville, E.A.3    Brizuela, L.4    Worland, P.J.5
  • 35
    • 84900330481 scopus 로고    scopus 로고
    • Chemical inhibition of NAT10 corrects defects of laminopathic cells
    • Larrieu D, Britton S, Demir M, Rodriguez R, Jackson SP Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014; 344: 527-532.
    • (2014) Science , vol.344 , pp. 527-532
    • Larrieu, D.1    Britton, S.2    Demir, M.3    Rodriguez, R.4    Jackson, S.P.5
  • 37
    • 79960902908 scopus 로고    scopus 로고
    • Structure and stability of the lamin A tail domain and HGPS mutant
    • Qin Z, Kalinowski A, Dahl KN, Buehler MJ Structure and stability of the lamin A tail domain and HGPS mutant. J Struct Biol. 2011; 175: 425-433.
    • (2011) J Struct Biol , vol.175 , pp. 425-433
    • Qin, Z.1    Kalinowski, A.2    Dahl, K.N.3    Buehler, M.J.4
  • 38
    • 84902465522 scopus 로고    scopus 로고
    • Functional architecture of the cell's nucleus in development, aging, and disease
    • Burke B, Stewart CL Functional architecture of the cell's nucleus in development, aging, and disease. Curr Top Dev Biol. 2014; 109: 1-52.
    • (2014) Curr Top Dev Biol , vol.109 , pp. 1-52
    • Burke, B.1    Stewart, C.L.2
  • 39
    • 33144478270 scopus 로고    scopus 로고
    • Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody
    • McClintock D, Gordon LB, Djabali K Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. Proc Natl Acad Sci U S A. 2006; 103: 2154-2159.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2154-2159
    • McClintock, D.1    Gordon, L.B.2    Djabali, K.3
  • 43
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human aging
    • Scaffidi P, Misteli T Lamin A-dependent nuclear defects in human aging. Science. 2006; 312: 1059-1063.
    • (2006) Science , vol.312 , pp. 1059-1063
    • Scaffidi, P.1    Misteli, T.2
  • 44
    • 34247356070 scopus 로고    scopus 로고
    • A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
    • Cao K, Capell BC, Erdos MR, Djabali K, Collins FS A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells. Proc Natl Acad Sci U S A. 2007; 104: 4949-4954.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 4949-4954
    • Cao, K.1    Capell, B.C.2    Erdos, M.R.3    Djabali, K.4    Collins, F.S.5
  • 45
    • 41649101975 scopus 로고    scopus 로고
    • The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin
    • McClintock D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin. PLoS One. 2007; 2: e1269.
    • (2007) PLoS One , vol.2
    • McClintock, D.1    Ratner, D.2    Lokuge, M.3    Owens, D.M.4    Gordon, L.B.5    Collins, F.S.6    Djabali, K.7
  • 47
    • 33745363911 scopus 로고    scopus 로고
    • DNA Damage Signaling and p53-dependent Senescence after Prolonged beta-Interferon Stimulation
    • Moiseeva O, Mallette FA, Mukhopadhyay UK, Moores A, Ferbeyre G DNA Damage Signaling and p53-dependent Senescence after Prolonged beta-Interferon Stimulation. Mol Biol Cell. 2006; 17: 1583-1592.
    • (2006) Mol Biol Cell , vol.17 , pp. 1583-1592
    • Moiseeva, O.1    Mallette, F.A.2    Mukhopadhyay, U.K.3    Moores, A.4    Ferbeyre, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.