HIF-1α regulates EMT via the Snail and β-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis

Journal of Cellular and Molecular Medicine

Volumn 20, Issue 4, 2016, Pages 688-697

  Zhu, Yong ^a   Tan, Jiuting ^a   Xie, Hui ^a   Wang, Jinfeng ^a   Meng, Xiaoxiao ^a   Wang, Ruilan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Epithelial mesenchymal transition; Hypoxia inducible factor 1 ; Paraquat; Pulmonary fibrosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN ZO1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; CTNNB1 PROTEIN, RAT; HIF1A PROTEIN, RAT; PARAQUAT; SNAI1 PROTEIN, RAT; TJP1 PROTEIN, RAT;

A549 CELL LINE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY ASSAY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM CELL; LUNG FIBROSIS; MALE; NONHUMAN; PARAQUAT POISONING; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RLE 6TN CELL LINE; TRANSIENT TRANSFECTION; WESTERN BLOTTING; A-549 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMICALLY INDUCED; DISEASE COURSE; GENETICS; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

A549 CELLS; ANIMALS; BETA CATENIN; CELL LINE; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; PARAQUAT; PULMONARY ALVEOLI; PULMONARY FIBROSIS; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SNAIL FAMILY TRANSCRIPTION FACTORS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84961214621     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12769     Document Type: Article

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