Hypoxia-induced Bmi1 promotes renal tubular epithelial cell-mesenchymal transition and renal fibrosis via PI3K/Akt signal

Molecular Biology of the Cell

Volumn 25, Issue 17, 2014, Pages 2650-2659

  Du, Rui ^a,b   Xia, Lin ^b   Ning, Xiaoxuan ^c   Liu, Limin ^b   Sun, Wenjuan ^b   Huang, Chen ^b   Wang, Hanmin ^b   Sun, Shiren ^b  

^a NAVY GENERAL HOSPITAL   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; FIBRONECTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN ZO1; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; VIMENTIN; BMI1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; MESSENGER RNA; NUCLEAR PROTEIN; TWIST1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE COURSE; EPITHELIAL MESENCHYMAL TRANSITION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; KIDNEY BIOPSY; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; MALE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; CELL HYPOXIA; GENE EXPRESSION REGULATION; GENETICS; KIDNEY TUBULE; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; TUMOR MICROENVIRONMENT;

ANIMALS; CELL HYPOXIA; CELLULAR MICROENVIRONMENT; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY TUBULES; MALE; NUCLEAR PROTEINS; POLYCOMB REPRESSIVE COMPLEX 1; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TWIST TRANSCRIPTION FACTOR;

EID: 84907222948     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E14-01-0044     Document Type: Article

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