Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Singhal, Garima ^a   Fisher, Ffolliott Martin ^a   Chee, Melissa J ^a   Tan, Tze Guan ^b   El Ouaamari, Abdelfattah ^c   Adams, Andrew C ^d   Najarian, Robert ^b   Kulkarni, Rohit N ^c   Benoist, Christophe ^b   Flier, Jeffrey S ^a   Maratos Flier, Eleftheria ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c JOSLIN DIABETES CENTER   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 21; GAMMA INTERFERON; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; T LYMPHOCYTE RECEPTOR BETA CHAIN; THY 1 ANTIGEN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; FAT INTAKE; FIBROBLAST GROWTH FACTOR; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; MAPK1 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; INFLAMMATION; INFLAMMATORY INFILTRATE; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET CELL; PANCREAS ISLET CELL HYPERPLASIA; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; ADVERSE EFFECTS; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; DIET RESTRICTION; FAT INTAKE; GENE EXPRESSION REGULATION; GENETICS; HYPERPLASIA; METABOLISM; PANCREAS ISLET; PANCREATITIS; PATHOLOGY; SIGNAL TRANSDUCTION;

ACINAR CELLS; ANIMALS; ANTIGENS, THY-1; DIET, HIGH-FAT; DIETARY FATS; FASTING; FIBROBLAST GROWTH FACTORS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HYPERPLASIA; INFLAMMATION; INTERFERON-GAMMA; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OBESITY; ORGAN SPECIFICITY; PANCREATITIS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84960970251     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148252     Document Type: Article

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