High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model

Cancer Prevention Research

Volumn 6, Issue 10, 2013, Pages 1064-1073

  Dawson, David W ^a   Hertzer, Kathleen ^a   Moro, Aune ^a   Donald, Graham ^a   Chang, Hui Hua ^a   Go, Vay Liang ^a   Pandol, Steven J ^a,c,d   Lugea, Aurelia ^a,c   Gukovskaya, Anna S ^a,c   Li, Gang ^a,b   Hines, Oscar J ^a   Rozengurt, Enrique ^a   Eibl, Guido ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^d CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CELL INFILTRATION; CLINICAL FEATURE; CONTROLLED STUDY; EARLY CANCER; FEMALE; HIGH CALORIE DIET; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERLEPTINEMIA; INFLAMMATORY CELL; LIPID DIET; MACROPHAGE; MALE; METABOLIC DISORDER; MOUSE MODEL; NONHUMAN; OBESITY; PANCREAS CANCER; PRIORITY JOURNAL; PROGENY; RAT; T LYMPHOCYTE; TUMOR PROMOTION; WEIGHT GAIN;

ACTINS; ANIMALS; BODY WEIGHT; CARCINOMA, PANCREATIC DUCTAL; CHEMOKINES; CYTOKINES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ENERGY INTAKE; FEMALE; FIBRONECTINS; GENES, RAS; GENOTYPE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; OBESITY; PANCREATIC NEOPLASMS; RAS PROTEINS;

EID: 84887898693     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-13-0065     Document Type: Article

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