CdSe/ZnS quantum dots induce hepatocyte pyroptosis and liver inflammation via NLRP3 inflammasome activation

Biomaterials

Volumn 90, Issue , 2016, Pages 27-39

  Lu, Yonghui ^a   Xu, Shangcheng ^a   Chen, Haiyan ^b   He, Mindi ^a   Deng, Youcai ^a   Cao, Zhengwang ^a   Pi, Huifeng ^a   Chen, Chunhai ^a   Li, Min ^a   Ma, Qinlong ^a   Gao, Peng ^a   Ji, Yan ^a   Zhang, Lei ^a   Yu, Zhengping ^a   Zhou, Zhou ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

Author keywords

Calcium mobilization; Hepatocyte pyroptosis; Liver inflammation; NLRP3; Quantum dots; Reactive oxygen species

Indexed keywords

CALCIUM; CELL DEATH; CHEMICAL ACTIVATION; MEDICAL APPLICATIONS; NANOCRYSTALS; PATHOLOGY;

BIOMEDICAL APPLICATIONS; CALCIUM MOBILIZATION; CDSE/ZNS QUANTUM DOTS; DOSE-DEPENDENT MANNER; HEPATOCYTES; NLRP3; REACTIVE OXYGEN SPECIES; TOXICOLOGICAL IMPACT;

SEMICONDUCTOR QUANTUM DOTS;

CADMIUM SELENIDE; CALCIUM; INFLAMMASOME; QUANTUM DOT; REACTIVE OXYGEN METABOLITE; ZINC SULFIDE; CADMIUM DERIVATIVE; CRYOPYRIN; SELENIUM DERIVATIVE; SULFIDE; ZINC DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM MOBILIZATION; CELL DEATH; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; HEPATITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; LIVER DYSFUNCTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYROPTOSIS; ANIMAL; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; IMMUNOLOGY; INFLAMMATION; LIVER;

ANIMALS; CADMIUM COMPOUNDS; CELL LINE; HEPATOCYTES; HUMANS; INFLAMMASOMES; INFLAMMATION; LIVER; MALE; MICE, INBRED C57BL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PYROPTOSIS; QUANTUM DOTS; REACTIVE OXYGEN SPECIES; SELENIUM COMPOUNDS; SULFIDES; ZINC COMPOUNDS;

EID: 84960936364     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.03.003     Document Type: Article

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