Cadmium telluride quantum dots cause oxidative stress leading to extrinsic and intrinsic apoptosis in hepatocellular carcinoma HepG2 cells

Toxicology

Volumn 306, Issue , 2013, Pages 114-123

  Nguyen, Kathy C ^a,b   Willmore, William G ^b   Tayabali, Azam F ^a  

^a Environmental Health Center   (Canada)

^b CARLETON UNIVERSITY   (Canada)

Author keywords

Apoptosis; CdTe quantum dots; Mitochondria; Nanoparticles; Oxidative stress; Reactive oxygen species

Indexed keywords

CADMIUM TELLURIDE; CASPASE 3; CASPASE 8; CATALASE; CYTOCHROME C; FAS ANTIGEN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 10; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; QUANTUM DOT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIVER CELL CARCINOMA; OXIDATIVE STRESS; PRIORITY JOURNAL;

APOPTOSIS; CADMIUM COMPOUNDS; CARCINOMA, HEPATOCELLULAR; CATALASE; CELL SURVIVAL; CYTOCHROMES C; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; QUANTUM DOTS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TELLURIUM;

EID: 84875249687     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.02.010     Document Type: Article

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