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Volumn 34, Issue 34, 2013, Pages 8741-8755

The role of surface chemistry in determining invivo biodistribution and toxicity of CdSe/ZnS core-shell quantum dots

Author keywords

Drug delivery; Imaging; Nanomedicine; Quantum dot; Surface chemistry; Toxicity

Indexed keywords

BIODISTRIBUTIONS; CORE-SHELL QUANTUM DOTS; INVIVO EVALUATIONS; LONG TERM EXPOSURE; POLYDIALLYLDIMETHYL AMMONIUM CHLORIDE; POSITIVELY CHARGED; PULMONARY EMBOLISM; QUANTUM DOT;

EID: 84882846247     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.07.087     Document Type: Article
Times cited : (134)

References (65)
  • 2
    • 34250001748 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles deliver DNA and chemicals into plants
    • Torney F., Trewyn B.G., Lin V.S.Y., Wang K. Mesoporous silica nanoparticles deliver DNA and chemicals into plants. Nat Nanotechnol 2007, 2:295-300.
    • (2007) Nat Nanotechnol , vol.2 , pp. 295-300
    • Torney, F.1    Trewyn, B.G.2    Lin, V.S.Y.3    Wang, K.4
  • 3
    • 54549113498 scopus 로고    scopus 로고
    • Invivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR
    • Mortensen L.J., Oberdorster G., Pentland A.P., DeLouise L.A. Invivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR. Nano Lett 2008, 8:2779-2787.
    • (2008) Nano Lett , vol.8 , pp. 2779-2787
    • Mortensen, L.J.1    Oberdorster, G.2    Pentland, A.P.3    DeLouise, L.A.4
  • 6
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • Nel A., Xia T., Madler L., Li N. Toxic potential of materials at the nanolevel. Science 2006, 311:622-627.
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3    Li, N.4
  • 8
    • 40449122796 scopus 로고    scopus 로고
    • Nanoparticle-mediated cellular response is size-dependent
    • Jiang W., Kim B.Y.S., Rutka J.T., Chan W.C.W. Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnol 2008, 3:145-150.
    • (2008) Nat Nanotechnol , vol.3 , pp. 145-150
    • Jiang, W.1    Kim, B.Y.S.2    Rutka, J.T.3    Chan, W.C.W.4
  • 9
    • 45849144754 scopus 로고    scopus 로고
    • Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles
    • Verma A., Uzun O., Hu Y.H., Hu Y., Han H.S., Watson N., et al. Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. Nat Mater 2008, 7:588-595.
    • (2008) Nat Mater , vol.7 , pp. 588-595
    • Verma, A.1    Uzun, O.2    Hu, Y.H.3    Hu, Y.4    Han, H.S.5    Watson, N.6
  • 10
    • 67649491055 scopus 로고    scopus 로고
    • Understanding biophysicochemical interactions at the nano-bio interface
    • Nel A.E., Madler L., Velegol D., Xia T., Hoek E.M.V., Somasundaran P., et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 2009, 8:543-557.
    • (2009) Nat Mater , vol.8 , pp. 543-557
    • Nel, A.E.1    Madler, L.2    Velegol, D.3    Xia, T.4    Hoek, E.M.V.5    Somasundaran, P.6
  • 11
    • 77649094886 scopus 로고    scopus 로고
    • The effects of size, shape, and surface functional group of gold nanostructures on their adsorption and internalization by cells
    • Cho E.C., Au L., Zhang Q., Xia Y.N. The effects of size, shape, and surface functional group of gold nanostructures on their adsorption and internalization by cells. Small 2010, 6:517-522.
    • (2010) Small , vol.6 , pp. 517-522
    • Cho, E.C.1    Au, L.2    Zhang, Q.3    Xia, Y.N.4
  • 12
    • 38849111818 scopus 로고    scopus 로고
    • Cytotoxicity of nanoparticles
    • Lewinski N., Colvin V., Drezek R. Cytotoxicity of nanoparticles. Small 2008, 4:26-49.
    • (2008) Small , vol.4 , pp. 26-49
    • Lewinski, N.1    Colvin, V.2    Drezek, R.3
  • 14
    • 80053922007 scopus 로고    scopus 로고
    • Cellular toxicity of inorganic nanoparticles: common aspects and guidelines for improved nanotoxicity evaluation
    • Soenen S.J., Rivera-Gil P., Montenegro J.M., Parak W.J., De Smedt S.C., Braeckmans K. Cellular toxicity of inorganic nanoparticles: common aspects and guidelines for improved nanotoxicity evaluation. Nano Today 2011, 6:446-465.
    • (2011) Nano Today , vol.6 , pp. 446-465
    • Soenen, S.J.1    Rivera-Gil, P.2    Montenegro, J.M.3    Parak, W.J.4    De Smedt, S.C.5    Braeckmans, K.6
  • 15
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • Oberdorster G., Oberdorster E., Oberdorster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 2005, 113:823-839.
    • (2005) Environ Health Perspect , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 16
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia M.A., McNeil S.E. Immunological properties of engineered nanomaterials. Nat Nanotechnol 2007, 2:469-478.
    • (2007) Nat Nanotechnol , vol.2 , pp. 469-478
    • Dobrovolskaia, M.A.1    McNeil, S.E.2
  • 17
    • 79551672488 scopus 로고    scopus 로고
    • Nanotoxicology: an interdisciplinary challenge
    • Krug H.F., Wick P. Nanotoxicology: an interdisciplinary challenge. Angew Chem Int Ed 2011, 50:1260-1278.
    • (2011) Angew Chem Int Ed , vol.50 , pp. 1260-1278
    • Krug, H.F.1    Wick, P.2
  • 19
    • 46749091612 scopus 로고    scopus 로고
    • Bioconjugated quantum dots for invivo molecular and cellular imaging
    • Smith A.M., Duan H.W., Mohs A.M., Nie S.M. Bioconjugated quantum dots for invivo molecular and cellular imaging. Adv Drug Deliv Rev 2008, 60:1226-1240.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1226-1240
    • Smith, A.M.1    Duan, H.W.2    Mohs, A.M.3    Nie, S.M.4
  • 20
    • 77958047761 scopus 로고    scopus 로고
    • Designing multifunctional quantum dots for bioimaging, detection, and drug delivery
    • Zrazhevskiy P., Sena M., Gao X.H. Designing multifunctional quantum dots for bioimaging, detection, and drug delivery. Chem Soc Rev 2010, 39:4326-4354.
    • (2010) Chem Soc Rev , vol.39 , pp. 4326-4354
    • Zrazhevskiy, P.1    Sena, M.2    Gao, X.H.3
  • 21
    • 67649202724 scopus 로고    scopus 로고
    • Mechanisms of quantum dot nanoparticle cellular uptake
    • Zhang L.W., Monteiro-Riviere N.A. Mechanisms of quantum dot nanoparticle cellular uptake. Toxicol Sci 2009, 110:138-155.
    • (2009) Toxicol Sci , vol.110 , pp. 138-155
    • Zhang, L.W.1    Monteiro-Riviere, N.A.2
  • 22
    • 80053100185 scopus 로고    scopus 로고
    • The effect of CdSeZnS quantum dots on calcium currents and catecholamine secretion in mouse chromaffin cells
    • Gosso S., Gavello D., Giachello C.N.G., Franchino C., Carbone E., Carabelli V. The effect of CdSeZnS quantum dots on calcium currents and catecholamine secretion in mouse chromaffin cells. Biomaterials 2011, 32:9040-9050.
    • (2011) Biomaterials , vol.32 , pp. 9040-9050
    • Gosso, S.1    Gavello, D.2    Giachello, C.N.G.3    Franchino, C.4    Carbone, E.5    Carabelli, V.6
  • 23
    • 78650379518 scopus 로고    scopus 로고
    • Strategies for the intracellular delivery of nanoparticles
    • Chou L.Y.T., Ming K., Chan W.C.W. Strategies for the intracellular delivery of nanoparticles. Chem Soc Rev 2011, 40:233-245.
    • (2011) Chem Soc Rev , vol.40 , pp. 233-245
    • Chou, L.Y.T.1    Ming, K.2    Chan, W.C.W.3
  • 25
    • 9644268826 scopus 로고    scopus 로고
    • Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification
    • Hoshino A., Fujioka K., Oku T., Suga M., Sasaki Y.F., Ohta T., et al. Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett 2004, 4:2163-2169.
    • (2004) Nano Lett , vol.4 , pp. 2163-2169
    • Hoshino, A.1    Fujioka, K.2    Oku, T.3    Suga, M.4    Sasaki, Y.F.5    Ohta, T.6
  • 26
    • 79959283434 scopus 로고    scopus 로고
    • Quantum dot cytotoxicity invitro: an investigation into the cytotoxic effects of a series of different surface chemistries and their core/shell materials
    • Clift M.J.D., Varet J., Hankin S.M., Brownlee B., Davidson A.M., Brandenberger C., et al. Quantum dot cytotoxicity invitro: an investigation into the cytotoxic effects of a series of different surface chemistries and their core/shell materials. Nanotoxicology 2011, 5:664-674.
    • (2011) Nanotoxicology , vol.5 , pp. 664-674
    • Clift, M.J.D.1    Varet, J.2    Hankin, S.M.3    Brownlee, B.4    Davidson, A.M.5    Brandenberger, C.6
  • 27
    • 84856436072 scopus 로고    scopus 로고
    • Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake
    • Walkey C.D., Olsen J.B., Guo H.B., Emili A., Chan W.C.W. Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake. JAm Chem Soc 2011, 134:2139-2147.
    • (2011) JAm Chem Soc , vol.134 , pp. 2139-2147
    • Walkey, C.D.1    Olsen, J.B.2    Guo, H.B.3    Emili, A.4    Chan, W.C.W.5
  • 28
    • 0842287342 scopus 로고    scopus 로고
    • Probing the cytotoxicity of semiconductor quantum dots
    • Derfus A.M., Chan W.C.W., Bhatia S.N. Probing the cytotoxicity of semiconductor quantum dots. Nano Lett 2004, 4:11-18.
    • (2004) Nano Lett , vol.4 , pp. 11-18
    • Derfus, A.M.1    Chan, W.C.W.2    Bhatia, S.N.3
  • 29
    • 32044451341 scopus 로고    scopus 로고
    • Atoxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors
    • Hardman R. Atoxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect 2006, 114:165-172.
    • (2006) Environ Health Perspect , vol.114 , pp. 165-172
    • Hardman, R.1
  • 30
    • 67649871487 scopus 로고    scopus 로고
    • Invitro toxicity testing of nanoparticles in 3D cell culture
    • Lee J., Lilly G.D., Doty R.C., Podsiadlo P., Kotov N.A. Invitro toxicity testing of nanoparticles in 3D cell culture. Small 2009, 5:1213-1221.
    • (2009) Small , vol.5 , pp. 1213-1221
    • Lee, J.1    Lilly, G.D.2    Doty, R.C.3    Podsiadlo, P.4    Kotov, N.A.5
  • 31
    • 49749139012 scopus 로고    scopus 로고
    • Computational and ultrastructural toxicology of a nanoparticle, quantum dot 705, in mice
    • Lin P.P., Chen J.W., Chang L.W., Wu J.P., Redding L., Chang H., et al. Computational and ultrastructural toxicology of a nanoparticle, quantum dot 705, in mice. Environ Sci Technol 2008, 42:6264-6270.
    • (2008) Environ Sci Technol , vol.42 , pp. 6264-6270
    • Lin, P.P.1    Chen, J.W.2    Chang, L.W.3    Wu, J.P.4    Redding, L.5    Chang, H.6
  • 33
    • 80655128383 scopus 로고    scopus 로고
    • Cd/Se/Te-based quantum dot 705 modulated redox homeostasis with hepatotoxicity in mice
    • Lin C.H., Yang M.H., Chang L.W., Yang C.S., Chang H., Chang W.H., et al. Cd/Se/Te-based quantum dot 705 modulated redox homeostasis with hepatotoxicity in mice. Nanotoxicology 2011, 5:650-663.
    • (2011) Nanotoxicology , vol.5 , pp. 650-663
    • Lin, C.H.1    Yang, M.H.2    Chang, L.W.3    Yang, C.S.4    Chang, H.5    Chang, W.H.6
  • 34
    • 80053308050 scopus 로고    scopus 로고
    • CdSe quantum dot (QD)-induced morphological and functional impairments to liver in mice
    • Liu W., Zhang S.P., Wang L.X., Qu C., Zhang C.W., Hong L., et al. CdSe quantum dot (QD)-induced morphological and functional impairments to liver in mice. PLoS ONE 2011, 6:e24406.
    • (2011) PLoS ONE , vol.6
    • Liu, W.1    Zhang, S.P.2    Wang, L.X.3    Qu, C.4    Zhang, C.W.5    Hong, L.6
  • 35
    • 84872163391 scopus 로고    scopus 로고
    • Quantum Dot 705, a cadmium-based nanoparticle, induces persistent inflammation and granuloma formation in the mouse lung
    • Ho C.C., Chang H., Tsai H.T., Tsai M.H., Yang C.S., Ling Y.C., et al. Quantum Dot 705, a cadmium-based nanoparticle, induces persistent inflammation and granuloma formation in the mouse lung. Nanotoxicology 2013, 7:105-115.
    • (2013) Nanotoxicology , vol.7 , pp. 105-115
    • Ho, C.C.1    Chang, H.2    Tsai, H.T.3    Tsai, M.H.4    Yang, C.S.5    Ling, Y.C.6
  • 36
    • 84863692660 scopus 로고    scopus 로고
    • Apilot study in non-human primates shows no adverse response to intravenous injection of quantum dots
    • Ye L., Yong K.T., Liu L.W., Roy I., Hu R., Zhu J., et al. Apilot study in non-human primates shows no adverse response to intravenous injection of quantum dots. Nat Nanotechnol 2012, 7:453-458.
    • (2012) Nat Nanotechnol , vol.7 , pp. 453-458
    • Ye, L.1    Yong, K.T.2    Liu, L.W.3    Roy, I.4    Hu, R.5    Zhu, J.6
  • 37
    • 84855742399 scopus 로고    scopus 로고
    • Mechanisms underlying toxicity induced by CdTe quantum dots determined in an invertebrate model organism
    • Ambrosone A., Mattera L., Marchesano V., Quarta A., Susha A.S., Tino A., et al. Mechanisms underlying toxicity induced by CdTe quantum dots determined in an invertebrate model organism. Biomaterials 2012, 33:1991-2000.
    • (2012) Biomaterials , vol.33 , pp. 1991-2000
    • Ambrosone, A.1    Mattera, L.2    Marchesano, V.3    Quarta, A.4    Susha, A.S.5    Tino, A.6
  • 38
    • 84874411650 scopus 로고    scopus 로고
    • Lung toxicity and biodistribution of Cd/Se-ZnS quantum dots with different surface functional groups after pulmonary exposure in rats
    • Roberts J.R., Antonini J.M., Porter D.W., Chapman R.S., Scabilloni J.F., Young S.H., et al. Lung toxicity and biodistribution of Cd/Se-ZnS quantum dots with different surface functional groups after pulmonary exposure in rats. Part Fibre Toxicol 2013, 10:1-17.
    • (2013) Part Fibre Toxicol , vol.10 , pp. 1-17
    • Roberts, J.R.1    Antonini, J.M.2    Porter, D.W.3    Chapman, R.S.4    Scabilloni, J.F.5    Young, S.H.6
  • 39
    • 33745913004 scopus 로고    scopus 로고
    • Pharmacokinetics of nanoscale quantum dots: invivo distribution, sequestration, and clearance in the rat
    • Fischer H.C., Liu L.C., Pang K.S., Chan W.C.W. Pharmacokinetics of nanoscale quantum dots: invivo distribution, sequestration, and clearance in the rat. Adv Funct Mater 2006, 16:1299-1305.
    • (2006) Adv Funct Mater , vol.16 , pp. 1299-1305
    • Fischer, H.C.1    Liu, L.C.2    Pang, K.S.3    Chan, W.C.W.4
  • 40
    • 34748905976 scopus 로고    scopus 로고
    • Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment
    • Yang R.S.H., Chang L.W., Wu J.P., Tsai M.H., Wang H.J., Kuo Y.C., et al. Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment. Environ Health Perspect 2007, 115:1339-1343.
    • (2007) Environ Health Perspect , vol.115 , pp. 1339-1343
    • Yang, R.S.H.1    Chang, L.W.2    Wu, J.P.3    Tsai, M.H.4    Wang, H.J.5    Kuo, Y.C.6
  • 43
    • 58149465608 scopus 로고    scopus 로고
    • Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice
    • Schipper M.L., Lyer G., Koh A.L., Cheng Z., Ebenstein Y., Aharoni A., et al. Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice. Small 2009, 5:126-134.
    • (2009) Small , vol.5 , pp. 126-134
    • Schipper, M.L.1    Lyer, G.2    Koh, A.L.3    Cheng, Z.4    Ebenstein, Y.5    Aharoni, A.6
  • 44
    • 78049323834 scopus 로고    scopus 로고
    • Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future
    • Gil P.R., Oberdorster G., Elder A., Puntes V., Parak W.J. Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future. ACS Nano 2010, 4:5527-5531.
    • (2010) ACS Nano , vol.4 , pp. 5527-5531
    • Gil, P.R.1    Oberdorster, G.2    Elder, A.3    Puntes, V.4    Parak, W.J.5
  • 45
    • 0141885391 scopus 로고    scopus 로고
    • Large-scale synthesis of nearly monodisperse CdSe/CdS core/shell nanocrystals using air-stable reagents via successive ion layer adsorption and reaction
    • Li J.J., Wang Y.A., Guo W.Z., Keay J.C., Mishima T.D., Johnson M.B., et al. Large-scale synthesis of nearly monodisperse CdSe/CdS core/shell nanocrystals using air-stable reagents via successive ion layer adsorption and reaction. JAm Chem Soc 2003, 125:12567-12575.
    • (2003) JAm Chem Soc , vol.125 , pp. 12567-12575
    • Li, J.J.1    Wang, Y.A.2    Guo, W.Z.3    Keay, J.C.4    Mishima, T.D.5    Johnson, M.B.6
  • 46
    • 36749058505 scopus 로고    scopus 로고
    • Bright, multicoloured light-emitting diodes based on quantum dots
    • Sun Q.J., Wang Y.A., Li L.S., Wang D.Y., Zhu T., Xu J., et al. Bright, multicoloured light-emitting diodes based on quantum dots. Nat Photonics 2007, 1:717-722.
    • (2007) Nat Photonics , vol.1 , pp. 717-722
    • Sun, Q.J.1    Wang, Y.A.2    Li, L.S.3    Wang, D.Y.4    Zhu, T.5    Xu, J.6
  • 47
    • 3543022686 scopus 로고    scopus 로고
    • Invivo cancer targeting and imaging with semiconductor quantum dots
    • Gao X.H., Cui Y.Y., Levenson R.M., Chung L.W.K., Nie S.M. Invivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 2004, 22:969-976.
    • (2004) Nat Biotechnol , vol.22 , pp. 969-976
    • Gao, X.H.1    Cui, Y.Y.2    Levenson, R.M.3    Chung, L.W.K.4    Nie, S.M.5
  • 49
    • 0037816199 scopus 로고    scopus 로고
    • Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals
    • Yu W.W., Qu L.H., Guo W.Z., Peng X.G. Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals. Chem Mater 2003, 15:2854-2860.
    • (2003) Chem Mater , vol.15 , pp. 2854-2860
    • Yu, W.W.1    Qu, L.H.2    Guo, W.Z.3    Peng, X.G.4
  • 51
    • 0347473808 scopus 로고    scopus 로고
    • Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping
    • Kim S., Lim Y.T., Soltesz E.G., De Grand A.M., Lee J., Nakayama A., et al. Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat Biotechnol 2004, 22:93-97.
    • (2004) Nat Biotechnol , vol.22 , pp. 93-97
    • Kim, S.1    Lim, Y.T.2    Soltesz, E.G.3    De Grand, A.M.4    Lee, J.5    Nakayama, A.6
  • 53
    • 70349100115 scopus 로고    scopus 로고
    • Biocompatible nar-infrared quantum dots as ultrasensitive probes for long-term invivo imaging applications
    • Yong K.T., Roy I., Ding H., Bergey E.J., Prasad P.N. Biocompatible nar-infrared quantum dots as ultrasensitive probes for long-term invivo imaging applications. Small 2009, 5:1997-2004.
    • (2009) Small , vol.5 , pp. 1997-2004
    • Yong, K.T.1    Roy, I.2    Ding, H.3    Bergey, E.J.4    Prasad, P.N.5
  • 54
    • 33751245917 scopus 로고    scopus 로고
    • Evaluation of quantum dot cytotoxicity based on intracellular uptake
    • Chang E., Thekkek N., Yu W.W., Colvin V.L., Drezek R. Evaluation of quantum dot cytotoxicity based on intracellular uptake. Small 2006, 2:1412-1417.
    • (2006) Small , vol.2 , pp. 1412-1417
    • Chang, E.1    Thekkek, N.2    Yu, W.W.3    Colvin, V.L.4    Drezek, R.5
  • 55
    • 38849085772 scopus 로고    scopus 로고
    • Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells
    • Hauck T.S., Ghazani A.A., Chan W.C.W. Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small 2008, 4:153-159.
    • (2008) Small , vol.4 , pp. 153-159
    • Hauck, T.S.1    Ghazani, A.A.2    Chan, W.C.W.3
  • 56
    • 3242685065 scopus 로고    scopus 로고
    • Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and invitro activity
    • Fischer D., Dautzenberg H., Kunath K., Kissel T. Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and invitro activity. Int J Pharm 2004, 280:253-269.
    • (2004) Int J Pharm , vol.280 , pp. 253-269
    • Fischer, D.1    Dautzenberg, H.2    Kunath, K.3    Kissel, T.4
  • 57
    • 40849086143 scopus 로고    scopus 로고
    • Functionalization of carbon nanotubes enables non-covalent binding and intracellular delivery of small interfering RNA for efficient knock-down of genes
    • Krajcik R., Jung A., Hirsch A., Neuhuber W., Zolk O. Functionalization of carbon nanotubes enables non-covalent binding and intracellular delivery of small interfering RNA for efficient knock-down of genes. Biochem Biophys Res Commun 2008, 369:595-602.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 595-602
    • Krajcik, R.1    Jung, A.2    Hirsch, A.3    Neuhuber, W.4    Zolk, O.5
  • 58
    • 77956706402 scopus 로고    scopus 로고
    • Antimicrobial particles from cationic lipid and polyelectrolytes
    • Melo L.D., Mamizuka E.M., Carmona-Ribeiro A.M. Antimicrobial particles from cationic lipid and polyelectrolytes. Langmuir 2010, 26:12300-12306.
    • (2010) Langmuir , vol.26 , pp. 12300-12306
    • Melo, L.D.1    Mamizuka, E.M.2    Carmona-Ribeiro, A.M.3
  • 59
    • 84859510563 scopus 로고    scopus 로고
    • The journey of a drug-carrier in the body: an anatomo-physiological perspective
    • Bertrand N., Leroux J.C. The journey of a drug-carrier in the body: an anatomo-physiological perspective. JControl Release 2012, 161:152-163.
    • (2012) JControl Release , vol.161 , pp. 152-163
    • Bertrand, N.1    Leroux, J.C.2
  • 60
    • 77950517381 scopus 로고    scopus 로고
    • Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats
    • Kutscher H.L., Chao P., Deshmukh M., Singh Y., Hu P., Joseph L.B., et al. Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats. JControl Release 2010, 143:31-37.
    • (2010) JControl Release , vol.143 , pp. 31-37
    • Kutscher, H.L.1    Chao, P.2    Deshmukh, M.3    Singh, Y.4    Hu, P.5    Joseph, L.B.6
  • 61
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: theory to practice
    • Moghimi S.M., Hunter A.C., Murray J.C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev 2001, 53:283-318.
    • (2001) Pharmacol Rev , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 62
    • 0018290009 scopus 로고
    • Fetal erythrocyte lifespan
    • Harrison K.L. Fetal erythrocyte lifespan. Aust Paediatr J 1979, 15:96-97.
    • (1979) Aust Paediatr J , vol.15 , pp. 96-97
    • Harrison, K.L.1
  • 63
    • 0036371914 scopus 로고    scopus 로고
    • Side-effects of a systemic injection of linear polyethylenimine-DNA complexes
    • Chollet P., Favrot M.C., Hurbin A., Coll J.L. Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. JGene Med 2002, 4:84-91.
    • (2002) JGene Med , vol.4 , pp. 84-91
    • Chollet, P.1    Favrot, M.C.2    Hurbin, A.3    Coll, J.L.4
  • 64
    • 34250770499 scopus 로고    scopus 로고
    • Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation
    • Akagi D., Oba M., Koyama H., Nishiyama N., Fukushima S., Miyata T., et al. Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation. Gene Ther 2007, 14:1029-1038.
    • (2007) Gene Ther , vol.14 , pp. 1029-1038
    • Akagi, D.1    Oba, M.2    Koyama, H.3    Nishiyama, N.4    Fukushima, S.5    Miyata, T.6
  • 65
    • 77953809654 scopus 로고    scopus 로고
    • Cationic carriers of genetic material and cell death: a mitochondrial tale
    • Hunter A.C., Moghimi S.M. Cationic carriers of genetic material and cell death: a mitochondrial tale. Biochim Biophys Acta 2010, 1797:1203-1209.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 1203-1209
    • Hunter, A.C.1    Moghimi, S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.