AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

Nature Communications

Volumn 7, Issue , 2016, Pages

  Johanns, M ^a   Lai, Y C ^a,f   Hsu, M F ^a,g   Jacobs, R ^a   Vertommen, D ^a   Van Sande, J ^b   Dumont, J E ^b   Woods, A ^c   Carling, D ^c   Hue, L ^a   Viollet, B ^d,e   Foretz, M ^d,e   Rider, M H ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d INSTITUT COCHIN   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f UNIVERSITY OF DUNDEE   (United Kingdom)

^g UNIVERSITY OF TAIPEI   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; CYCLIC AMP; GLUCAGON; ENZYME ACTIVATOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PDE4B PROTEIN, MOUSE; PHOSPHODIESTERASE IV;

CATALYSIS; CELLS AND CELL COMPONENTS; CONCENTRATION (COMPOSITION); ENZYME ACTIVITY; HORMONE; ORGANIC COMPOUND; PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; LIVER CELL; MOUSE; NONHUMAN; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; PROTEIN MOTIF;

AMINO ACID MOTIFS; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; ENZYME ACTIVATION; ENZYME ACTIVATORS; GLUCAGON; HEPATOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 84960427343     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10856     Document Type: Article

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