-
2
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0014887939
-
The concept of immunological surveillance
-
Burnet FM. The concept of immunological surveillance. Prog Exp Tumor Res 1970;13:1-27.
-
(1970)
Prog Exp Tumor Res
, vol.13
, pp. 1-27
-
-
Burnet, F.M.1
-
4
-
-
68849105814
-
Oncogenic stress sensed by the immune system: role of natural killer cell receptors
-
Raulet DH, Guerra N. Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat Rev Immunol 2009;9:568-80.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 568-580
-
-
Raulet, D.H.1
Guerra, N.2
-
5
-
-
0035953308
-
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
Shankaran V, Ikeda H, Bruce AT, et al. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001;410:1107-11.
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
-
6
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
Koebel CM, Vermi W, Swann JB, et al. Adaptive immunity maintains occult cancer in an equilibrium state. Nature 2007;450:903-7.
-
(2007)
Nature
, vol.450
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
-
7
-
-
0029804782
-
Decreased tumor surveillance in perforin-deficient mice
-
van den Broek ME, Kägi D, Ossendorp F, et al. Decreased tumor surveillance in perforin-deficient mice. J Exp Med 1996;184:1781-90.
-
(1996)
J Exp Med
, vol.184
, pp. 1781-1790
-
-
van den Broek, M.E.1
Kägi, D.2
Ossendorp, F.3
-
8
-
-
0035894946
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth
-
Takeda K, Smyth MJ, Cretney E, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth. Cell Immunol 2001;214:194-200.
-
(2001)
Cell Immunol
, vol.214
, pp. 194-200
-
-
Takeda, K.1
Smyth, M.J.2
Cretney, E.3
-
9
-
-
38149139518
-
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis
-
Finnberg N, Klein-Szanto AJ, El-Deiry WS. TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. J Clin Invest 2008;118:111-23.
-
(2008)
J Clin Invest
, vol.118
, pp. 111-123
-
-
Finnberg, N.1
Klein-Szanto, A.J.2
El-Deiry, W.S.3
-
10
-
-
49149108257
-
AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice
-
Nepal RM, Zaheen A, Basit W, et al. AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice. Oncogene 2008;27:4752-6.
-
(2008)
Oncogene
, vol.27
, pp. 4752-4756
-
-
Nepal, R.M.1
Zaheen, A.2
Basit, W.3
-
11
-
-
0035914134
-
Regulation of cutaneous malignancy by gammadelta T cells
-
Girardi M, Oppenheim DE, Steele CR, et al. Regulation of cutaneous malignancy by gammadelta T cells. Science 2001;294:605-9.
-
(2001)
Science
, vol.294
, pp. 605-609
-
-
Girardi, M.1
Oppenheim, D.E.2
Steele, C.R.3
-
12
-
-
41549163195
-
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
-
Guerra N, Tan YX, Joncker NT, et al. NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 2008;28:571-80.
-
(2008)
Immunity
, vol.28
, pp. 571-580
-
-
Guerra, N.1
Tan, Y.X.2
Joncker, N.T.3
-
13
-
-
46949109577
-
Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness
-
Willimsky G, Czéh M, Loddenkemper C, et al. Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness. J Exp Med 2008;205:1687-700.
-
(2008)
J Exp Med
, vol.205
, pp. 1687-1700
-
-
Willimsky, G.1
Czéh, M.2
Loddenkemper, C.3
-
14
-
-
51649121390
-
Tumor escape mechanisms:potential role of soluble HLA antigens and NK cells activating ligands
-
Campoli M, Ferrone S. Tumor escape mechanisms:potential role of soluble HLA antigens and NK cells activating ligands. Tissue Antigens 2008;72:321-34.
-
(2008)
Tissue Antigens
, vol.72
, pp. 321-334
-
-
Campoli, M.1
Ferrone, S.2
-
15
-
-
59649091694
-
Accelerated tumor growth in mice deficient in DNAM-1 receptor
-
Iguchi-Manaka A, Kai H, Yamashita Y, et al. Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med 2008;205:2959-64.
-
(2008)
J Exp Med
, vol.205
, pp. 2959-2964
-
-
Iguchi-Manaka, A.1
Kai, H.2
Yamashita, Y.3
-
16
-
-
0034973005
-
Epidemiology of AIDS-related tumours in developed and developing countries
-
Dal Maso L, Serraino D, Franceschi S. Epidemiology of AIDS-related tumours in developed and developing countries. Eur J Cancer 2001;37:1188-201.
-
(2001)
Eur J Cancer
, vol.37
, pp. 1188-1201
-
-
Dal Maso, L.1
Serraino, D.2
Franceschi, S.3
-
17
-
-
1942476133
-
Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients
-
Ulrich C, Schmook T, Sachse MM, et al. Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients. Dermatol Surg 2004;30:622-7.
-
(2004)
Dermatol Surg
, vol.30
, pp. 622-627
-
-
Ulrich, C.1
Schmook, T.2
Sachse, M.M.3
-
18
-
-
84905639073
-
Cancer stem cell immunology:key to understanding tumorigenesis and tumor immune escape?
-
Bruttel VS, Wischhusen J. Cancer stem cell immunology:key to understanding tumorigenesis and tumor immune escape? Front Immunol 2014;5:360.
-
(2014)
Front Immunol
, vol.5
, pp. 360
-
-
Bruttel, V.S.1
Wischhusen, J.2
-
19
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K, Lutz C, van Delft FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011;469:356-61.
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
van Delft, F.W.3
-
20
-
-
84857789336
-
Understanding cancer stem cell heterogeneity and plasticity
-
Tang DG. Understanding cancer stem cell heterogeneity and plasticity. Cell Res 2012;22:457-72.
-
(2012)
Cell Res
, vol.22
, pp. 457-472
-
-
Tang, D.G.1
-
22
-
-
79960989834
-
Stem cell quiescence
-
Li L, Bhatia R. Stem cell quiescence. Clin Cancer Res 2011;17:4936-41.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4936-4941
-
-
Li, L.1
Bhatia, R.2
-
23
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao S, Wu Q, Li Z, et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res 2008;68:6043-8.
-
(2008)
Cancer Res
, vol.68
, pp. 6043-6048
-
-
Bao, S.1
Wu, Q.2
Li, Z.3
-
24
-
-
77956217454
-
T cells enhance stem-like properties and conditional malignancy in gliomas
-
Irvin DK, Jouanneau E, Duvall G, et al. T cells enhance stem-like properties and conditional malignancy in gliomas. PLoS One 2010;5:e10974.
-
(2010)
PLoS One
, vol.5
, pp. e10974
-
-
Irvin, D.K.1
Jouanneau, E.2
Duvall, G.3
-
25
-
-
18844392836
-
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
-
Hochedlinger K, Yamada Y, Beard C, et al. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 2005;121:465-77.
-
(2005)
Cell
, vol.121
, pp. 465-477
-
-
Hochedlinger, K.1
Yamada, Y.2
Beard, C.3
-
26
-
-
49249106900
-
Crucial role of interleukin-4 in the survival of colon cancer stem cells
-
Francipane MG, Alea MP, Lombardo Y, et al. Crucial role of interleukin-4 in the survival of colon cancer stem cells. Cancer Res 2008;68:4022-5.
-
(2008)
Cancer Res
, vol.68
, pp. 4022-4025
-
-
Francipane, M.G.1
Alea, M.P.2
Lombardo, Y.3
-
27
-
-
67650999875
-
The basics of epithelialmesenchymal transition
-
Kalluri R, Weinberg RA. The basics of epithelialmesenchymal transition. J Clin Invest 2009;119:1420-8.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
28
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007;1:555-67.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
-
29
-
-
80051761743
-
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
-
Kelly PN, Strasser A. The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ 2011;18:1414-24.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1414-1424
-
-
Kelly, P.N.1
Strasser, A.2
-
30
-
-
84893642085
-
Immunology of cancer stem cells in solid tumours. A review
-
Maccalli C, Volontè A, Cimminiello C, et al. Immunology of cancer stem cells in solid tumours. A review. Eur J Cancer 2014;50:649-55.
-
(2014)
Eur J Cancer
, vol.50
, pp. 649-655
-
-
Maccalli, C.1
Volontè, A.2
Cimminiello, C.3
-
31
-
-
84863035821
-
Cancer stem cells: distinct entities or dynamically regulated phenotypes?
-
Li Y, Laterra J. Cancer stem cells: distinct entities or dynamically regulated phenotypes? Cancer Res 2012;72:576-80.
-
(2012)
Cancer Res
, vol.72
, pp. 576-580
-
-
Li, Y.1
Laterra, J.2
-
32
-
-
83255193921
-
Interconversion between intestinal stem cell populations in distinct niches
-
Takeda N, Jain R, LeBoeuf MR, et al. Interconversion between intestinal stem cell populations in distinct niches. Science 2011;334:1420-4.
-
(2011)
Science
, vol.334
, pp. 1420-1424
-
-
Takeda, N.1
Jain, R.2
LeBoeuf, M.R.3
-
34
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 2007;7:834-46.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
35
-
-
79953151458
-
Cancer immunoediting:integrating immunity's roles in cancer suppression and promotion
-
Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting:integrating immunity's roles in cancer suppression and promotion. Science 2011;331:1565-70.
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
36
-
-
84894245627
-
Identification of preleukaemic haematopoietic stem cells in acute leukaemia
-
Shlush LI, Zandi S, Mitchell A, et al. Identification of preleukaemic haematopoietic stem cells in acute leukaemia. Nature 2014;506:328-33.
-
(2014)
Nature
, vol.506
, pp. 328-333
-
-
Shlush, L.I.1
Zandi, S.2
Mitchell, A.3
-
37
-
-
28644432204
-
VEGFR1- positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1- positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820-7.
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
-
39
-
-
79551600015
-
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
-
Takebe N, Harris PJ, Warren RQ, et al. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 2011;8:97-106.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 97-106
-
-
Takebe, N.1
Harris, P.J.2
Warren, R.Q.3
-
40
-
-
84922571419
-
MHC class I antigen presentation and implications for developing a new generation of therapeutic vaccines
-
Comber JD, Philip R. MHC class I antigen presentation and implications for developing a new generation of therapeutic vaccines. Ther Adv Vaccines 2014;2:77-89.
-
(2014)
Ther Adv Vaccines
, vol.2
, pp. 77-89
-
-
Comber, J.D.1
Philip, R.2
-
41
-
-
76049114698
-
Immunobiological characterization of cancer stem cells isolated from glioblastoma patients
-
Di Tomaso T, Mazzoleni S, Wang E, et al. Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin Cancer Res 2010;16:800-13.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 800-813
-
-
Di Tomaso, T.1
Mazzoleni, S.2
Wang, E.3
-
42
-
-
84940207002
-
Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy
-
Salem ML, El-Badawy AS, Li Z. Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy. Cytotechnology 2015;67:749-59.
-
(2015)
Cytotechnology
, vol.67
, pp. 749-759
-
-
Salem, M.L.1
El-Badawy, A.S.2
Li, Z.3
-
43
-
-
43049165453
-
The epithelialmesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al. The epithelialmesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
44
-
-
84861882582
-
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells
-
Tsuyada A, Chow A, Wu J, et al. CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res 2012;72:2768-79.
-
(2012)
Cancer Res
, vol.72
, pp. 2768-2779
-
-
Tsuyada, A.1
Chow, A.2
Wu, J.3
-
45
-
-
33847419142
-
Molecular definition of breast tumor heterogeneity
-
Shipitsin M, Campbell LL, Argani P, et al. Molecular definition of breast tumor heterogeneity. Cancer Cell 2007;11:259-73.
-
(2007)
Cancer Cell
, vol.11
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
-
46
-
-
34848866647
-
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
-
Todaro M, Alea MP, Di Stefano AB, et al. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. Cell Stem Cell 2007;1:389-402.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 389-402
-
-
Todaro, M.1
Alea, M.P.2
Di Stefano, A.B.3
-
47
-
-
36148958993
-
Co-expression of the toleragenic glycoprotein, CD200, with markers for cancer stem cells
-
Kawasaki BT, Mistree T, Hurt EM, et al. Co-expression of the toleragenic glycoprotein, CD200, with markers for cancer stem cells. Biochem Biophys Res Commun 2007;364:778-82.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 778-782
-
-
Kawasaki, B.T.1
Mistree, T.2
Hurt, E.M.3
-
48
-
-
84877057303
-
Mechanisms of chemoresistance in cancer stem cells
-
Abdullah LN, Chow EK. Mechanisms of chemoresistance in cancer stem cells. Clin Transl Med 2013;2:3.
-
(2013)
Clin Transl Med
, vol.2
, pp. 3
-
-
Abdullah, L.N.1
Chow, E.K.2
-
49
-
-
84903748693
-
Cancer stem cells in prostate cancer chemoresistance
-
Ni J, Cozzi P, Hao J, et al. Cancer stem cells in prostate cancer chemoresistance. Curr Cancer Drug Targets 2014;14:225-40.
-
(2014)
Curr Cancer Drug Targets
, vol.14
, pp. 225-240
-
-
Ni, J.1
Cozzi, P.2
Hao, J.3
-
50
-
-
84886949455
-
The two sides of HER2/neu:immune escape versus surveillance
-
Seliger B, Kiessling R. The two sides of HER2/neu:immune escape versus surveillance. Trends Mol Med 2013;19:677-84.
-
(2013)
Trends Mol Med
, vol.19
, pp. 677-684
-
-
Seliger, B.1
Kiessling, R.2
-
51
-
-
0036721716
-
Shaping gene expression in activated and resting primary macrophages by IL-10
-
Lang R, Patel D, Morris JJ, et al. Shaping gene expression in activated and resting primary macrophages by IL-10. J Immunol 2002;169:2253-63.
-
(2002)
J Immunol
, vol.169
, pp. 2253-2263
-
-
Lang, R.1
Patel, D.2
Morris, J.J.3
-
52
-
-
28644445445
-
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
-
Kortylewski M, Kujawski M, Wang T, et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 2005;11:1314-21.
-
(2005)
Nat Med
, vol.11
, pp. 1314-1321
-
-
Kortylewski, M.1
Kujawski, M.2
Wang, T.3
-
53
-
-
0031573204
-
Induction of tolerance by IL-10-treated dendritic cells
-
Steinbrink K, Wölfl M, Jonuleit H, et al. Induction of tolerance by IL-10-treated dendritic cells. J Immunol 1997;159:4772-80.
-
(1997)
J Immunol
, vol.159
, pp. 4772-4780
-
-
Steinbrink, K.1
Wölfl, M.2
Jonuleit, H.3
-
54
-
-
78049270536
-
Glioma cancer stem cells induce immunosuppressive macrophages/microglia
-
Wu A, Wei J, Kong LY, et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol 2010;12:1113-25.
-
(2010)
Neuro Oncol
, vol.12
, pp. 1113-1125
-
-
Wu, A.1
Wei, J.2
Kong, L.Y.3
-
55
-
-
35348841582
-
Universal and stemness-related tumor antigens: potential use in cancer immunotherapy
-
Parmiani G, Russo V, Marrari A, et al. Universal and stemness-related tumor antigens: potential use in cancer immunotherapy. Clin Cancer Res 2007;13:5675-9.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5675-5679
-
-
Parmiani, G.1
Russo, V.2
Marrari, A.3
-
56
-
-
42049109699
-
MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1
-
Engelmann K, Shen H, Finn OJ. MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1. Cancer Res 2008;68:2419-26.
-
(2008)
Cancer Res
, vol.68
, pp. 2419-2426
-
-
Engelmann, K.1
Shen, H.2
Finn, O.J.3
-
57
-
-
84857645984
-
Cytotoxic T lymphocytes: Sniping cancer stem cells
-
Hirohashi Y, Torigoe T, Inoda S, et al. Cytotoxic T lymphocytes: Sniping cancer stem cells. Oncoimmunology 2012;1:123-125.
-
(2012)
Oncoimmunology
, vol.1
, pp. 123-125
-
-
Hirohashi, Y.1
Torigoe, T.2
Inoda, S.3
-
58
-
-
38849151665
-
Epitope landscape in breast and colorectal cancer
-
Segal NH, Parsons DW, Peggs KS, et al. Epitope landscape in breast and colorectal cancer. Cancer Res 2008;68:889-92.
-
(2008)
Cancer Res
, vol.68
, pp. 889-892
-
-
Segal, N.H.1
Parsons, D.W.2
Peggs, K.S.3
-
59
-
-
76549126237
-
Modulation of T-cell activation by malignant melanoma initiating cells
-
Schatton T, Schütte U, Frank NY, et al. Modulation of T-cell activation by malignant melanoma initiating cells. Cancer Res 2010;70:697-708.
-
(2010)
Cancer Res
, vol.70
, pp. 697-708
-
-
Schatton, T.1
Schütte, U.2
Frank, N.Y.3
-
60
-
-
68549107867
-
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells
-
Gedye C, Quirk J, Browning J, et al. Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells. Cancer Immunol Immunother 2009;58:1635-46.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1635-1646
-
-
Gedye, C.1
Quirk, J.2
Browning, J.3
-
61
-
-
84885867020
-
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells
-
Koshio J, Kagamu H, Nozaki K, et al. DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells. Cancer Immunol Immunother 2013;62:1619-28.
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 1619-1628
-
-
Koshio, J.1
Kagamu, H.2
Nozaki, K.3
-
62
-
-
77954238710
-
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
-
Boiko AD, Razorenova OV, van de Rijn M, et al. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 2010;466:133-7.
-
(2010)
Nature
, vol.466
, pp. 133-137
-
-
Boiko, A.D.1
Razorenova, O.V.2
van de Rijn, M.3
-
63
-
-
84859820456
-
Stem-like tumorinitiating cells isolated from IL13Rα2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T Cells
-
Brown CE, Starr R, Aguilar B, et al. Stem-like tumorinitiating cells isolated from IL13Rα2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T Cells. Clin Cancer Res 2012;18:2199-209.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2199-2209
-
-
Brown, C.E.1
Starr, R.2
Aguilar, B.3
-
64
-
-
79953668877
-
Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells
-
Inoda S, Hirohashi Y, Torigoe T, et al. Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells. Am J Pathol 2011;178:1805-13.
-
(2011)
Am J Pathol
, vol.178
, pp. 1805-1813
-
-
Inoda, S.1
Hirohashi, Y.2
Torigoe, T.3
-
65
-
-
84856804158
-
EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell-mediated immunotherapy
-
Mitra M, Kandalam M, Harilal A, et al. EpCAM is a putative stem marker in retinoblastoma and an effective target for T-cell-mediated immunotherapy. Mol Vis 2012;18:290-308.
-
(2012)
Mol Vis
, vol.18
, pp. 290-308
-
-
Mitra, M.1
Kandalam, M.2
Harilal, A.3
-
66
-
-
84861746437
-
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA
-
136ra68
-
Forshew T, Murtaza M, Parkinson C, et al. Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Sci Transl Med 2012;4:136ra68.
-
(2012)
Sci Transl Med
, vol.4
-
-
Forshew, T.1
Murtaza, M.2
Parkinson, C.3
-
67
-
-
79952993517
-
Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development
-
Moitra K, Lou H, Dean M. Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development. Clin Pharmacol Ther 2011;89:491-502.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 491-502
-
-
Moitra, K.1
Lou, H.2
Dean, M.3
-
68
-
-
84908376404
-
Immunotherapy for non-small cell lung cancer
-
Yoon SH. Immunotherapy for non-small cell lung cancer. Tuberc Respir Dis (Seoul) 2014;77:111-5.
-
(2014)
Tuberc Respir Dis (Seoul)
, vol.77
, pp. 111-115
-
-
Yoon, S.H.1
-
69
-
-
52649163840
-
Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer
-
Al-Shibli KI, Donnem T, Al-Saad S, et al. Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer. Clin Cancer Res 2008;14:5220-7.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5220-5227
-
-
Al-Shibli, K.I.1
Donnem, T.2
Al-Saad, S.3
-
70
-
-
58149234402
-
Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage
-
Koyama K, Kagamu H, Miura S, et al. Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage. Clin Cancer Res 2008;14:6770-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6770-6779
-
-
Koyama, K.1
Kagamu, H.2
Miura, S.3
-
71
-
-
51349090152
-
Alteration of the immunological synapse in lung cancer: a microenvironmental approach
-
Derniame S, Vignaud JM, Faure GC, et al. Alteration of the immunological synapse in lung cancer: a microenvironmental approach. Clin Exp Immunol 2008;154:48-55.
-
(2008)
Clin Exp Immunol
, vol.154
, pp. 48-55
-
-
Derniame, S.1
Vignaud, J.M.2
Faure, G.C.3
-
72
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
73
-
-
77951255645
-
Immunity to stemness genes in human cancer
-
Dhodapkar MV. Immunity to stemness genes in human cancer. Curr Opin Immunol 2010;22:245-50.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 245-250
-
-
Dhodapkar, M.V.1
-
74
-
-
33847052535
-
Mechanisms of malignant glioma immune resistance and sources of immunosuppression
-
Gomez GG, Kruse CA. Mechanisms of malignant glioma immune resistance and sources of immunosuppression. Gene Ther Mol Biol 2006;10:133-46.
-
(2006)
Gene Ther Mol Biol
, vol.10
, pp. 133-146
-
-
Gomez, G.G.1
Kruse, C.A.2
-
75
-
-
84904112296
-
Immunotherapy in the treatment of non-small cell lung cancer
-
Sundar R, Soong R, Cho BC, et al. Immunotherapy in the treatment of non-small cell lung cancer. Lung Cancer 2014;85:101-9.
-
(2014)
Lung Cancer
, vol.85
, pp. 101-109
-
-
Sundar, R.1
Soong, R.2
Cho, B.C.3
-
77
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12:252-64.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
78
-
-
84874830056
-
Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types
-
Ascierto PA, Kalos M, Schaer DA, et al. Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types. Clin Cancer Res 2013;19:1009-20.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1009-1020
-
-
Ascierto, P.A.1
Kalos, M.2
Schaer, D.A.3
-
79
-
-
84937545889
-
Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints
-
Karachaliou N, Cao MG, Teixidó C, et al. Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints. Cancer Biol Med 2015;12:79-86.
-
(2015)
Cancer Biol Med
, vol.12
, pp. 79-86
-
-
Karachaliou, N.1
Cao, M.G.2
Teixidó, C.3
-
80
-
-
77952144984
-
Adecatumumab: an anti-EpCAM monoclonal antibody, from the bench to the bedside
-
Kurtz JE, Dufour P. Adecatumumab: an anti-EpCAM monoclonal antibody, from the bench to the bedside. Expert Opin Biol Ther 2010;10:951-8.
-
(2010)
Expert Opin Biol Ther
, vol.10
, pp. 951-958
-
-
Kurtz, J.E.1
Dufour, P.2
-
81
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996;271:1734-6.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
82
-
-
84863689866
-
Novel antimelanoma immunotherapies: disarming tumor escape mechanisms
-
Sapoznik S, Hammer O, Ortenberg R, et al. Novel antimelanoma immunotherapies: disarming tumor escape mechanisms. Clin Dev Immunol 2012;2012:818214.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 818214
-
-
Sapoznik, S.1
Hammer, O.2
Ortenberg, R.3
-
83
-
-
84892485531
-
Immune checkpoint inhibitors:making immunotherapy a reality for the treatment of lung cancer
-
Brahmer JR, Pardoll DM. Immune checkpoint inhibitors:making immunotherapy a reality for the treatment of lung cancer. Cancer Immunol Res 2013;1:85-91.
-
(2013)
Cancer Immunol Res
, vol.1
, pp. 85-91
-
-
Brahmer, J.R.1
Pardoll, D.M.2
-
84
-
-
84863911486
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer:results from a randomized, double-blind, multicenter phase II study
-
Lynch TJ, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer:results from a randomized, double-blind, multicenter phase II study. J Clin Oncol 2012;30:2046-54.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2046-2054
-
-
Lynch, T.J.1
Bondarenko, I.2
Luft, A.3
-
85
-
-
84904252059
-
Molecular pathways and therapeutic targets in lung cancer
-
Shtivelman E, Hensing T, Simon GR, et al. Molecular pathways and therapeutic targets in lung cancer. Oncotarget 2014;5:1392-433.
-
(2014)
Oncotarget
, vol.5
, pp. 1392-1433
-
-
Shtivelman, E.1
Hensing, T.2
Simon, G.R.3
-
86
-
-
84890933630
-
Update on immune checkpoint inhibitors in lung cancer
-
Creelan BC. Update on immune checkpoint inhibitors in lung cancer. Cancer Control 2014;21:80-9.
-
(2014)
Cancer Control
, vol.21
, pp. 80-89
-
-
Creelan, B.C.1
-
87
-
-
76749084659
-
Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinumbased therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC)
-
Zatloukal P, Heo DS, Park K, et al. Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinumbased therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC). J Clin Oncol 2009;27:15s.
-
(2009)
J Clin Oncol
, vol.27
, pp. 15s
-
-
Zatloukal, P.1
Heo, D.S.2
Park, K.3
-
88
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Agata Y, Kawasaki A, Nishimura H, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 1996;8:765-72.
-
(1996)
Int Immunol
, vol.8
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
-
89
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1027-34.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
-
90
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002;8:793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
-
91
-
-
84888340426
-
A phase I dose-escalation and cohort expansion study of lirilumab (anti-KIR; BMS-986015) administered in combination with nivolumab (anti-PD-1; BMS-936558; ONO-4538) in patients (Pts) with advanced refractory solid tumors
-
Sanborn RE, Sharfman WH, Segal NH, et al. A phase I dose-escalation and cohort expansion study of lirilumab (anti-KIR; BMS-986015) administered in combination with nivolumab (anti-PD-1; BMS-936558; ONO-4538) in patients (Pts) with advanced refractory solid tumors. J Clin Oncol 2013;31:abstr TPS3110.
-
(2013)
J Clin Oncol
, vol.31
-
-
Sanborn, R.E.1
Sharfman, W.H.2
Segal, N.H.3
-
92
-
-
84929456860
-
Cancer immunotherapy: a future paradigm shift in the treatment of non-small cell lung cancer
-
Anagnostou VK, Brahmer JR. Cancer immunotherapy: a future paradigm shift in the treatment of non-small cell lung cancer. Clin Cancer Res 2015;21:976-84.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 976-984
-
-
Anagnostou, V.K.1
Brahmer, J.R.2
-
93
-
-
84908269560
-
Nivolumab (anti-PD-1; BMS-936558, ONO-4538) and ipilimumab in first-line NSCLC: Interim phase I results
-
Antonia SJ, Gettinger SN, Chow LQ, et al. Nivolumab (anti-PD-1; BMS-936558, ONO-4538) and ipilimumab in first-line NSCLC: Interim phase I results. J Clin Oncol 2014;32:5s.
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Antonia, S.J.1
Gettinger, S.N.2
Chow, L.Q.3
-
94
-
-
0037438490
-
Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation:attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses
-
Bennett F, Luxenberg D, Ling V, et al. Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation:attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. J Immunol 2003;170:711-8.
-
(2003)
J Immunol
, vol.170
, pp. 711-718
-
-
Bennett, F.1
Luxenberg, D.2
Ling, V.3
-
95
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012;366:2455-65.
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
96
-
-
84887262315
-
A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors
-
abstr
-
Herbst RS, Gordon MS, Fine GD, et al. A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors. J Clin Oncol 2013;31:abstr 3000.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3000
-
-
Herbst, R.S.1
Gordon, M.S.2
Fine, G.D.3
-
97
-
-
84960191619
-
-
PD-L1 expression and prior treatment history in patients with non-small cell lung cancer (NSCLC) following PD-L1 blockade with MPDL3280A (anti-PDL1). Available online
-
Gordon MS. MO18.01 - An analysis of the relationship of clinical activity to baseline EGFR status, PD-L1 expression and prior treatment history in patients with non-small cell lung cancer (NSCLC) following PD-L1 blockade with MPDL3280A (anti-PDL1). Available online: http://library. iaslc.org/search-speaker?search_speaker=22102
-
MO18.01 - An analysis of the relationship of clinical activity to baseline EGFR status
-
-
Gordon, M.S.1
-
98
-
-
33748098860
-
PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis
-
Mühlbauer M, Fleck M, Schütz C, et al. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis. J Hepatol 2006;45:520-8.
-
(2006)
J Hepatol
, vol.45
, pp. 520-528
-
-
Mühlbauer, M.1
Fleck, M.2
Schütz, C.3
-
99
-
-
0032979212
-
Long survival of patients with small cell lung cancer after adjuvant treatment with the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guérin
-
Grant SC, Kris MG, Houghton AN, et al. Long survival of patients with small cell lung cancer after adjuvant treatment with the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guérin. Clin Cancer Res 1999;5:1319-23.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1319-1323
-
-
Grant, S.C.1
Kris, M.G.2
Houghton, A.N.3
-
100
-
-
27244446896
-
Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease smallcell lung cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study)
-
Giaccone G, Debruyne C, Felip E, et al. Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease smallcell lung cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study). J Clin Oncol 2005;23:6854-64.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6854-6864
-
-
Giaccone, G.1
Debruyne, C.2
Felip, E.3
-
101
-
-
58149456558
-
Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody
-
Hernández AM, Toledo D, Martínez D, et al. Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody. J Immunol 2008;181:6625-34.
-
(2008)
J Immunol
, vol.181
, pp. 6625-6634
-
-
Hernández, A.M.1
Toledo, D.2
Martínez, D.3
-
102
-
-
30944446883
-
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
-
Jain RK, Duda DG, Clark JW, et al. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006;3:24-40.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 24-40
-
-
Jain, R.K.1
Duda, D.G.2
Clark, J.W.3
-
103
-
-
0036660176
-
Role of GITR in activation response of T lymphocytes
-
Ronchetti S, Nocentini G, Riccardi C, et al. Role of GITR in activation response of T lymphocytes. Blood 2002;100:350-2.
-
(2002)
Blood
, vol.100
, pp. 350-352
-
-
Ronchetti, S.1
Nocentini, G.2
Riccardi, C.3
-
104
-
-
0032534582
-
Ox-40 ligand:a potent costimulatory molecule for sustaining primary CD4 T cell responses
-
Gramaglia I, Weinberg AD, Lemon M, et al. Ox-40 ligand:a potent costimulatory molecule for sustaining primary CD4 T cell responses. J Immunol 1998;161:6510-7.
-
(1998)
J Immunol
, vol.161
, pp. 6510-6517
-
-
Gramaglia, I.1
Weinberg, A.D.2
Lemon, M.3
-
105
-
-
84891275907
-
OX40 is a potent immune-stimulating target in late-stage cancer patients
-
Curti BD, Kovacsovics-Bankowski M, Morris N, et al. OX40 is a potent immune-stimulating target in late-stage cancer patients. Cancer Res 2013;73:7189-98.
-
(2013)
Cancer Res
, vol.73
, pp. 7189-7198
-
-
Curti, B.D.1
Kovacsovics-Bankowski, M.2
Morris, N.3
-
106
-
-
84900034656
-
Combined anti-CD40 and anti-IL-23 monoclonal antibody therapy effectively suppresses tumor growth and metastases
-
von Scheidt B, Leung PS, Yong MC, et al. Combined anti-CD40 and anti-IL-23 monoclonal antibody therapy effectively suppresses tumor growth and metastases. Cancer Res 2014;74:2412-21.
-
(2014)
Cancer Res
, vol.74
, pp. 2412-2421
-
-
von Scheidt, B.1
Leung, P.S.2
Yong, M.C.3
-
107
-
-
78149235833
-
EpCAM in carcinogenesis: the good, the bad or the ugly
-
van der Gun BT, Melchers LJ, Ruiters MH, et al. EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis 2010;31:1913-21.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1913-1921
-
-
van der Gun, B.T.1
Melchers, L.J.2
Ruiters, M.H.3
-
108
-
-
28744445538
-
MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors
-
Brischwein K, Schlereth B, Guller B, et al. MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. Mol Immunol 2006;43:1129-43.
-
(2006)
Mol Immunol
, vol.43
, pp. 1129-1143
-
-
Brischwein, K.1
Schlereth, B.2
Guller, B.3
-
109
-
-
84867733430
-
A phase I study of EpCAM/CD3-bispecific antibody (MT110) in patients with advanced solid tumors
-
abstr
-
Fiedler WM, Wolf M, Kebenko M, et al. A phase I study of EpCAM/CD3-bispecific antibody (MT110) in patients with advanced solid tumors. J Clin Oncol 2012;30:abstr 2504.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2504
-
-
Fiedler, W.M.1
Wolf, M.2
Kebenko, M.3
-
110
-
-
84872902302
-
CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges
-
Grosse-Gehling P, Fargeas CA, Dittfeld C, et al. CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges. J Pathol 2013;229:355-78.
-
(2013)
J Pathol
, vol.229
, pp. 355-378
-
-
Grosse-Gehling, P.1
Fargeas, C.A.2
Dittfeld, C.3
-
111
-
-
84883244302
-
Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo
-
Huang J, Li C, Wang Y, et al. Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo. Clin Immunol 2013;149:156-68.
-
(2013)
Clin Immunol
, vol.149
, pp. 156-168
-
-
Huang, J.1
Li, C.2
Wang, Y.3
-
112
-
-
77952343328
-
Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
-
Matsuzaki J, Gnjatic S, Mhawech-Fauceglia P, et al. Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. Proc Natl Acad Sci U S A 2010;107:7875-80.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7875-7880
-
-
Matsuzaki, J.1
Gnjatic, S.2
Mhawech-Fauceglia, P.3
-
114
-
-
0027464958
-
Heterogeneity of mucin gene expression in normal and neoplastic tissues
-
Ho SB, Niehans GA, Lyftogt C, et al. Heterogeneity of mucin gene expression in normal and neoplastic tissues. Cancer Res 1993;53:641-51.
-
(1993)
Cancer Res
, vol.53
, pp. 641-651
-
-
Ho, S.B.1
Niehans, G.A.2
Lyftogt, C.3
-
115
-
-
0031914321
-
Cancerassociated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2
-
Agrawal B, Krantz MJ, Reddish MA, et al. Cancerassociated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2. Nat Med 1998;4:43-9.
-
(1998)
Nat Med
, vol.4
, pp. 43-49
-
-
Agrawal, B.1
Krantz, M.J.2
Reddish, M.A.3
-
116
-
-
0032545730
-
Immunogenicity and antitumor activity of a liposomal MUC1 peptide-based vaccine
-
Samuel J, Budzynski WA, Reddish MA, et al. Immunogenicity and antitumor activity of a liposomal MUC1 peptide-based vaccine. Int J Cancer 1998;75:295-302.
-
(1998)
Int J Cancer
, vol.75
, pp. 295-302
-
-
Samuel, J.1
Budzynski, W.A.2
Reddish, M.A.3
-
117
-
-
27244449289
-
Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
-
Butts C, Murray N, Maksymiuk A, et al. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol 2005;23:6674-81.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6674-6681
-
-
Butts, C.1
Murray, N.2
Maksymiuk, A.3
-
118
-
-
80054742888
-
Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25):phase IIB randomized, multicenter, open-label trial
-
Butts C, Maksymiuk A, Goss G, et al. Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25):phase IIB randomized, multicenter, open-label trial. J Cancer Res Clin Oncol 2011;137:1337-42.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 1337-1342
-
-
Butts, C.1
Maksymiuk, A.2
Goss, G.3
-
119
-
-
0034789572
-
Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer
-
Palmer M, Parker J, Modi S, et al. Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer. Clin Lung Cancer 2001;3:49-57; discussion 58.
-
(2001)
Clin Lung Cancer
, vol.3
-
-
Palmer, M.1
Parker, J.2
Modi, S.3
-
120
-
-
79952304769
-
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
-
Robbins PF, Morgan RA, Feldman SA, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol 2011;29:917-24.
-
(2011)
J Clin Oncol
, vol.29
, pp. 917-924
-
-
Robbins, P.F.1
Morgan, R.A.2
Feldman, S.A.3
-
121
-
-
84880720167
-
Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy
-
Ulloa-Montoya F, Louahed J, Dizier B, et al. Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy. J Clin Oncol 2013;31:2388-95.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2388-2395
-
-
Ulloa-Montoya, F.1
Louahed, J.2
Dizier, B.3
-
122
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
Sharma SV, Bell DW, Settleman J, et al. Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 2007;7:169-81.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 169-181
-
-
Sharma, S.V.1
Bell, D.W.2
Settleman, J.3
-
123
-
-
0032928459
-
Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer. Lung Cancer Study Group
-
Reissmann PT, Koga H, Figlin RA, et al. Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer. Lung Cancer Study Group. J Cancer Res Clin Oncol 1999;125:61-70.
-
(1999)
J Cancer Res Clin Oncol
, vol.125
, pp. 61-70
-
-
Reissmann, P.T.1
Koga, H.2
Figlin, R.A.3
-
124
-
-
84892157282
-
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase
-
Iversen TZ, Engell-Noerregaard L, Ellebaek E, et al. Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clin Cancer Res 2014;20:221-32.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 221-232
-
-
Iversen, T.Z.1
Engell-Noerregaard, L.2
Ellebaek, E.3
-
125
-
-
80455140226
-
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
-
Brunsvig PF, Kyte JA, Kersten C, et al. Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial. Clin Cancer Res 2011;17:6847-57.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6847-6857
-
-
Brunsvig, P.F.1
Kyte, J.A.2
Kersten, C.3
-
126
-
-
0037143087
-
Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers
-
Oji Y, Miyoshi S, Maeda H, et al. Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers. Int J Cancer 2002;100:297-303.
-
(2002)
Int J Cancer
, vol.100
, pp. 297-303
-
-
Oji, Y.1
Miyoshi, S.2
Maeda, H.3
-
127
-
-
4644289323
-
Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression
-
Oka Y, Tsuboi A, Taguchi T, et al. Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression. Proc Natl Acad Sci U S A 2004;101:13885-90.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13885-13890
-
-
Oka, Y.1
Tsuboi, A.2
Taguchi, T.3
-
128
-
-
0032751204
-
A cyclophilin B gene encodes antigenic epitopes recognized by HLAA24- restricted and tumor-specific CTLs
-
Gomi S, Nakao M, Niiya F, et al. A cyclophilin B gene encodes antigenic epitopes recognized by HLAA24- restricted and tumor-specific CTLs. J Immunol 1999;163:4994-5004.
-
(1999)
J Immunol
, vol.163
, pp. 4994-5004
-
-
Gomi, S.1
Nakao, M.2
Niiya, F.3
-
129
-
-
33750586798
-
Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer
-
Nemunaitis J, Dillman RO, Schwarzenberger PO, et al. Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer. J Clin Oncol 2006;24:4721-30.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4721-4730
-
-
Nemunaitis, J.1
Dillman, R.O.2
Schwarzenberger, P.O.3
-
130
-
-
52449108084
-
Induction of immune responses and clinical efficacy in a phase II trial of IDM-2101, a 10-epitope cytotoxic T-lymphocyte vaccine, in metastatic non-small-cell lung cancer
-
Barve M, Bender J, Senzer N, et al. Induction of immune responses and clinical efficacy in a phase II trial of IDM-2101, a 10-epitope cytotoxic T-lymphocyte vaccine, in metastatic non-small-cell lung cancer. J Clin Oncol 2008;26:4418-25.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4418-4425
-
-
Barve, M.1
Bender, J.2
Senzer, N.3
-
131
-
-
32944468708
-
Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer
-
Antonia SJ, Mirza N, Fricke I, et al. Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer. Clin Cancer Res 2006;12:878-87.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 878-887
-
-
Antonia, S.J.1
Mirza, N.2
Fricke, I.3
-
132
-
-
0030000287
-
Human lung cancer cells endogenously expressing mutant p53 process and present the mutant epitope and are lysed by mutantspecific cytotoxic T lymphocytes
-
Ciernik IF, Berzofsky JA, Carbone DP. Human lung cancer cells endogenously expressing mutant p53 process and present the mutant epitope and are lysed by mutantspecific cytotoxic T lymphocytes. Clin Cancer Res 1996;2:877-82.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 877-882
-
-
Ciernik, I.F.1
Berzofsky, J.A.2
Carbone, D.P.3
-
133
-
-
77952135152
-
INGN-225:a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect
-
Chiappori AA, Soliman H, Janssen WE, et al. INGN-225:a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect. Expert Opin Biol Ther 2010;10:983-91.
-
(2010)
Expert Opin Biol Ther
, vol.10
, pp. 983-991
-
-
Chiappori, A.A.1
Soliman, H.2
Janssen, W.E.3
|