-
1
-
-
79953059789
-
Natural innate and adaptive immunity to cancer
-
Vesely M. D., Kershaw M. H., Schreiber R. D., Smyth M. J., Natural innate and adaptive immunity to cancer Annual Review of Immunology 2011 29 235 271
-
(2011)
Annual Review of Immunology
, vol.29
, pp. 235-271
-
-
Vesely, M.D.1
Kershaw, M.H.2
Schreiber, R.D.3
Smyth, M.J.4
-
2
-
-
79954533158
-
Shifting the equilibrium in cancer immunoediting: From tumor tolerance to eradication
-
Quezada S. A., Peggs K. S., Simpson T. R., Allison J. P., Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication Immunological Reviews 2011 241 1 104 118
-
(2011)
Immunological Reviews
, vol.241
, Issue.1
, pp. 104-118
-
-
Quezada, S.A.1
Peggs, K.S.2
Simpson, T.R.3
Allison, J.P.4
-
3
-
-
79953151458
-
Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
-
Schreiber R. D., Old L. J., Smyth M. J., Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion Science 2011 331 6024 1565 1570
-
(2011)
Science
, vol.331
, Issue.6024
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
4
-
-
53549087527
-
How tumours escape mass destruction
-
Stewart T. J., Abrams S. I., How tumours escape mass destruction Oncogene 2008 27 45 5894 5903
-
(2008)
Oncogene
, vol.27
, Issue.45
, pp. 5894-5903
-
-
Stewart, T.J.1
Abrams, S.I.2
-
5
-
-
79960899604
-
Camouflage and sabotage: Tumor escape from the immune system
-
Poschke I., Mougiakakos D., Kiessling R., Camouflage and sabotage: tumor escape from the immune system Cancer Immunology, Immunotherapy 2011 60 8 1161 1171
-
(2011)
Cancer Immunology, Immunotherapy
, vol.60
, Issue.8
, pp. 1161-1171
-
-
Poschke, I.1
Mougiakakos, D.2
Kiessling, R.3
-
6
-
-
79955829822
-
The mechanisms of cancer immunoescape and development of overcoming strategies
-
Yaguchi T., Sumimoto H., Kudo-Saito C., Tsukamoto N., Ueda R., Iwata-Kajihara T., Nishio H., Kawamura N., Kawakami Y., The mechanisms of cancer immunoescape and development of overcoming strategies International Journal of Hematology 2011 93 3 294 300
-
(2011)
International Journal of Hematology
, vol.93
, Issue.3
, pp. 294-300
-
-
Yaguchi, T.1
Sumimoto, H.2
Kudo-Saito, C.3
Tsukamoto, N.4
Ueda, R.5
Iwata-Kajihara, T.6
Nishio, H.7
Kawamura, N.8
Kawakami, Y.9
-
8
-
-
0034781113
-
Malignant melanoma
-
Slominski A., Wortsman J., Carlson A. J., Matsuoka L. Y., Balch C. M., Mihm M. C., Malignant melanoma Archives of Pathology and Laboratory Medicine 2001 125 10 1295 1306
-
(2001)
Archives of Pathology and Laboratory Medicine
, vol.125
, Issue.10
, pp. 1295-1306
-
-
Slominski, A.1
Wortsman, J.2
Carlson, A.J.3
Matsuoka, L.Y.4
Balch, C.M.5
Mihm, M.C.6
-
9
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A., Siegel R., Ward E., Murray T., Xu J., Thun M. J., Cancer statistics, 2007 Ca-A Cancer Journal for Clinicians 2007 57 1 43 66 (Pubitemid 46148091)
-
(2007)
Ca-A Cancer Journal for Clinicians
, vol.57
, Issue.1
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
10
-
-
79959570631
-
Melanoma vaccines: Developments over the past 10 years
-
Klein O., Schmidt C., Knights A., Davis I. D., Chen W., Cebon J., Melanoma vaccines: developments over the past 10 years Expert Review of Vaccines 2011 10 6 853 873
-
(2011)
Expert Review of Vaccines
, vol.10
, Issue.6
, pp. 853-873
-
-
Klein, O.1
Schmidt, C.2
Knights, A.3
Davis, I.D.4
Chen, W.5
Cebon, J.6
-
11
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
DOI 10.1038/nrc2355, PII NRC2355
-
Rosenberg S. A., Restifo N. P., Yang J. C., Morgan R. A., Dudley M. E., Adoptive cell transfer: a clinical path to effective cancer immunotherapy Nature Reviews Cancer 2008 8 4 299 308 (Pubitemid 351430867)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.4
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
12
-
-
77952236279
-
B-RAF inhibitors: An evolving role in the therapy of malignant melanoma
-
Shepherd C., Puzanov I., Sosman J. A., B-RAF inhibitors: an evolving role in the therapy of malignant melanoma Current Oncology Reports 2010 12 3 146 152
-
(2010)
Current Oncology Reports
, vol.12
, Issue.3
, pp. 146-152
-
-
Shepherd, C.1
Puzanov, I.2
Sosman, J.A.3
-
13
-
-
78449243489
-
Immune checkpoint proteins: A new therapeutic paradigm for cancerpreclinical background: CTLA-4 and PD-1 blockade
-
Weber J., Immune checkpoint proteins: a new therapeutic paradigm for cancerpreclinical background: CTLA-4 and PD-1 blockade Seminars in Oncology 2010 37 5 430 439
-
(2010)
Seminars in Oncology
, vol.37
, Issue.5
, pp. 430-439
-
-
Weber, J.1
-
14
-
-
76149137243
-
Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy
-
Yuan J., Page D. B., Ku G. Y., Li Y., Mu Z., Ariyan C., Gallardo H. F., Roman R. A., Heine A. I., Terzulli S. L., Gnjatic S., Ritter G., Jungbluth A. A., Allison J. P., Old L. J., Wolchok J. D., Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy Cancer Immunity 2010 10, article 1
-
(2010)
Cancer Immunity
, vol.101
-
-
Yuan, J.1
Page, D.B.2
Ku, G.Y.3
Li, Y.4
Mu, Z.5
Ariyan, C.6
Gallardo, H.F.7
Roman, R.A.8
Heine, A.I.9
Terzulli, S.L.10
Gnjatic, S.11
Ritter, G.12
Jungbluth, A.A.13
Allison, J.P.14
Old, L.J.15
Wolchok, J.D.16
-
15
-
-
27144500671
-
+ T cells in patients with melanoma
-
Rosenberg S. A., Sherry R. M., Morton K. E., Scharfman W. J., Yang J. C., Topalian S. L., Royal R. E., Kammula U., Restifo N. P., Hughes M. S., Schwartzentruber D., Berman D. M., Schwarz S. L., Ngo L. T., Mavroukakis S. A., White D. E., Steinberg S. M., Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8 + T cells in patients with melanoma Journal of Immunology 2005 175 9 6169 6176 (Pubitemid 41508105)
-
(2005)
Journal of Immunology
, vol.175
, Issue.9
, pp. 6169-6176
-
-
Rosenberg, S.A.1
Sherry, R.M.2
Morton, K.E.3
Scharfman, W.J.4
Yang, J.C.5
Topalian, S.L.6
Royal, R.E.7
Kammula, U.8
Restifo, N.P.9
Hughes, M.S.10
Schwartzentruber, D.11
Berman, D.M.12
Schwarz, S.L.13
Ngo, L.T.14
Mavroukakis, S.A.15
White, D.E.16
Steinberg, S.M.17
-
16
-
-
4043079706
-
The paradox of T cell-mediated antitumor immunity in spite of poor clinical outcome in human melanoma
-
DOI 10.1007/s00262-004-0526-8
-
Anichini A., Vegetti C., Mortarini R., The paradox of T cell-mediated antitumor immunity in spite of poor clinical outcome in human melanoma Cancer Immunology, Immunotherapy 2004 53 10 855 864 (Pubitemid 39312653)
-
(2004)
Cancer Immunology, Immunotherapy
, vol.53
, Issue.10
, pp. 855-864
-
-
Anichini, A.1
Vegetti, C.2
Mortarini, R.3
-
17
-
-
33745632047
-
+ T cells in a patient with malignant melanoma ascites
-
DOI 10.1007/s00262-005-0118-2
-
Harlin H., Kuna T. V., Peterson A. C., Meng Y., Gajewski T. F., Tumor progression despite massive influx of activated CD8 + T cells in a patient with malignant melanoma ascites Cancer Immunology, Immunotherapy 2006 55 10 1185 1197 (Pubitemid 43992045)
-
(2006)
Cancer Immunology, Immunotherapy
, vol.55
, Issue.10
, pp. 1185-1197
-
-
Harlin, H.1
Kuna, T.V.2
Peterson, A.C.3
Meng, Y.4
Gajewski, T.F.5
-
18
-
-
0032193228
-
Expression and function of CTLA-4 in Th1 and Th2 cells
-
Alegre M. L., Shiels H., Thompson C. B., Gajewski T. F., Expression and function of CTLA-4 in Th1 and Th2 cells Journal of Immunology 1998 161 7 3347 3356
-
(1998)
Journal of Immunology
, vol.161
, Issue.7
, pp. 3347-3356
-
-
Alegre, M.L.1
Shiels, H.2
Thompson, C.B.3
Gajewski, T.F.4
-
19
-
-
1642396607
-
+ T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells
-
Munn D. H., Sharma M. D., Mellor A. L., Ligation of B7-1/B7-2 by human CD4 + T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells Journal of Immunology 2004 172 7 4100 4110 (Pubitemid 38375222)
-
(2004)
Journal of Immunology
, vol.172
, Issue.7
, pp. 4100-4110
-
-
Munn, D.H.1
Sharma, M.D.2
Mellor, A.L.3
-
20
-
-
27144458821
-
CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction
-
DOI 10.1002/ijc.21155
-
Contardi E., Palmisano G. L., Tazzari P. L., Martelli A. M., Fal F., Fabbi M., Kato T., Lucarelli E., Donati D., Polito L., Bolognesi A., Ricci F., Salvi S., Gargaglione V., Mantero S., Alberghini M., Ferrara G. B., Pistillo M. P., CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction International Journal of Cancer 2005 117 4 538 550 (Pubitemid 41504541)
-
(2005)
International Journal of Cancer
, vol.117
, Issue.4
, pp. 538-550
-
-
Contardi, E.1
Palmisano, G.L.2
Tazzari, P.L.3
Martelli, A.M.4
Fala, F.5
Fabbi, M.6
Kato, T.7
Lucarelli, E.8
Donati, D.9
Polito, L.10
Bolognesi, A.11
Ricci, F.12
Salvi, S.13
Gargaglione, V.14
Mantero, S.15
Alberghini, M.16
Ferrara, G.B.17
Pistillo, M.P.18
-
21
-
-
57349099365
-
CTLA-4 is a direct target of Wnt/ -catenin signaling and is expressed in human melanoma tumors
-
Shah K. V., Chien A. J., Yee C., Moon R. T., CTLA-4 is a direct target of Wnt/ -catenin signaling and is expressed in human melanoma tumors Journal of Investigative Dermatology 2008 128 12 2870 2879
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.12
, pp. 2870-2879
-
-
Shah, K.V.1
Chien, A.J.2
Yee, C.3
Moon, R.T.4
-
22
-
-
84863640874
-
Targeting CTLA-4 directly on melanoma cells: A possible novel perspective in the immunotherapy of cutaneous melanoma
-
supplement, abstract e22138
-
Queirolo P., Boitano M., Carrega P., Targeting CTLA-4 directly on melanoma cells: a possible novel perspective in the immunotherapy of cutaneous melanoma Journal of Clinical Oncology 2009 27 supplement, abstract e22138
-
(2009)
Journal of Clinical Oncology
, vol.27
-
-
Queirolo, P.1
Boitano, M.2
Carrega, P.3
-
23
-
-
57349156952
-
Tumor evasion may occur via expression of regulatory molecules: A case for CTLA-4 in melanoma
-
Weber J. S., Tumor evasion may occur via expression of regulatory molecules: a case for CTLA-4 in melanoma Journal of Investigative Dermatology 2008 128 12 2750 2752
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.12
, pp. 2750-2752
-
-
Weber, J.S.1
-
24
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol E. A., Borriello F., Schweitzer A. N., Lynch W. P., Bluestone J. A., Sharpe A. H., Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 Immunity 1995 3 5 541 547
-
(1995)
Immunity
, vol.3
, Issue.5
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
25
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P., Penninger J. M., Timms E., Wakeham A., Shahinian A., Lee K. P., Thompson C. B., Griesser H., Mak T. W., Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 Science 1995 270 5238 985 988
-
(1995)
Science
, vol.270
, Issue.5238
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
26
-
-
0033870234
-
B7-1, IFNγ and anti-CTLA-4 co-operate to prevent T-cell tolerization during immunotherapy against a murine T-lymphoma
-
DOI 10.1002/1097-0215 (20000815) 87:4<539:: AID-IJC13>3.0.CO;2-E
-
van Ginderachter J. A., Liu Y., Geldhof A. B., Brijs L., Thielemans K., B7-1, IFN gamma and anti-CTLA-4 co-operate to prevent T-cell tolerization during immunotherapy against a murine T-lymphoma International Journal of Cancer 2000 87 539 547 (Pubitemid 30639814)
-
(2000)
International Journal of Cancer
, vol.87
, Issue.4
, pp. 539-547
-
-
Van Ginderachter, J.A.1
Liu, Y.2
Geldhof, A.B.3
Brijs, L.4
Thielemans, K.5
De Baetselier, P.6
Raes, G.7
-
27
-
-
0034194329
-
Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade
-
Hurwitz A. A., Foster B. A., Kwon E. D., Truong T., Choi E. M., Greenberg N. M., Burg M. B., Allison J. P., Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade Cancer Research 2000 60 9 2444 2448 (Pubitemid 30262435)
-
(2000)
Cancer Research
, vol.60
, Issue.9
, pp. 2444-2448
-
-
Hurwitz, A.A.1
Foster, B.A.2
Kwon, E.D.3
Truong, T.4
Choi, E.M.5
Greenberg, N.M.6
Burg, M.B.7
Allison, J.P.8
-
28
-
-
0030743846
-
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
-
DOI 10.1073/pnas.94.15.8099
-
Kwon E. D., Hurwitz A. A., Foster B. A., Madias C., Feldhaus A. L., Greenberg N. M., Burg M. B., Allison J. P., Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer Proceedings of the National Academy of Sciences of the United States of America 1997 94 15 8099 8103 (Pubitemid 27343783)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.15
, pp. 8099-8103
-
-
Kwon, E.D.1
Hurwitz, A.A.2
Foster, B.A.3
Madias, C.4
Feldhaus, A.L.5
Greenberg, N.M.6
Burg, M.B.7
Allison, J.P.8
-
29
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach D. R., Krummel M. F., Allison J. P., Enhancement of antitumor immunity by CTLA-4 blockade Science 1996 271 5256 1734 1736 (Pubitemid 26102823)
-
(1996)
Science
, vol.271
, Issue.5256
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
30
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi F. S., O'Day S. J., McDermott D. F., Weber R. W., Sosman J. A., Haanen J. B., Gonzalez R., Robert C., Schadendorf D., Hassel J. C., Akerley W., Van Den Eertwegh A. J. M., Lutzky J., Lorigan P., Vaubel J. M., Linette G. P., Hogg D., Ottensmeier C. H., Lebbé C., Peschel C., Quirt I., Clark J. I., Wolchok J. D., Weber J. S., Tian J., Yellin M. J., Nichol G. M., Hoos A., Urba W. J., Improved survival with ipilimumab in patients with metastatic melanoma The New England Journal of Medicine 2010 363 8 711 723
-
(2010)
The New England Journal of Medicine
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
Van Den Eertwegh, A.J.M.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbé, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
31
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C., Thomas L., Bondarenko I., O'Day S., Weber J., Garbe C., Lebbe C., Baurain J. F., Testori A., Grob J. J., Davidson N., Richards J., Maio M., Hauschild A., Miller W. H., Gascon P., Lotem M., Harmankaya K., Ibrahim R., Francis S., Chen T. T., Humphrey R., Hoos A., Wolchok J. D., Ipilimumab plus dacarbazine for previously untreated metastatic melanoma The New England Journal of Medicine 2011 364 26 2517 2526
-
(2011)
The New England Journal of Medicine
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
Lebbe, C.7
Baurain, J.F.8
Testori, A.9
Grob, J.J.10
Davidson, N.11
Richards, J.12
Maio, M.13
Hauschild, A.14
Miller, W.H.15
Gascon, P.16
Lotem, M.17
Harmankaya, K.18
Ibrahim, R.19
Francis, S.20
Chen, T.T.21
Humphrey, R.22
Hoos, A.23
Wolchok, J.D.24
more..
-
32
-
-
84863640877
-
-
Ipilimumab Drugs in R D 2010 10 2 97 110
-
(2010)
Ipilimumab Drugs in R D
, vol.10
, Issue.2
, pp. 97-110
-
-
-
33
-
-
79251571760
-
The role of the PD-1 pathway in autoimmunity and peripheral tolerance
-
Fife B. T., Pauken K. E., The role of the PD-1 pathway in autoimmunity and peripheral tolerance Annals of the New York Academy of Sciences 2011 1217 1 45 59
-
(2011)
Annals of the New York Academy of Sciences
, vol.1217
, Issue.1
, pp. 45-59
-
-
Fife, B.T.1
Pauken, K.E.2
-
34
-
-
0037152153
-
Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues
-
DOI 10.1016/S0165-2478(02)00142-6, PII S0165247802001426
-
Ishida M., Iwai Y., Tanaka Y., Okazaki T., Freeman G. J., Minato N., Honjo T., Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues Immunology Letters 2002 84 1 57 62 (Pubitemid 34879920)
-
(2002)
Immunology Letters
, vol.84
, Issue.1
, pp. 57-62
-
-
Ishida, M.1
Iwai, Y.2
Tanaka, Y.3
Okazaki, T.4
Freeman, G.J.5
Minato, N.6
Honjo, T.7
-
36
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
DOI 10.1038/85330
-
Latchman Y., Wood C. R., Chernova T., Chaudhary D., Borde M., Chernova I., Iwai Y., Long A. J., Brown J. A., Nunes R., Greenfield E. A., Bourque K., Boussiotis V. A., Carter L. L., Carreno B. M., Malenkovich N., Nishimura H., Okazaki T., Honjo T., Sharpe A. H., Freeman G. J., PD-L2 is a second ligand for PD-1 and inhibits T cell activation Nature Immunology 2001 2 3 261 268 (Pubitemid 33706004)
-
(2001)
Nature Immunology
, vol.2
, Issue.3
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
Greenfield, E.A.11
Bourque, K.12
Boussiotis, V.A.13
Carter, L.L.14
Carreno, B.M.15
Malenkovich, N.16
Nishimura, H.17
Okazaki, T.18
Honjo, T.19
Sharpe, A.H.20
Freeman, G.J.21
more..
-
37
-
-
33746854425
-
Regulation of T cell activation and tolerance by PDL2
-
DOI 10.1073/pnas.0601347103
-
Zhang Y., Chung Y., Bishop C., Daugherty B., Chute H., Holst P., Kurahara C., Lott F., Sun N., Welcher A. A., Dong C., Regulation of T cell activation and tolerance by PDL2 Proceedings of the National Academy of Sciences of the United States of America 2006 103 31 11695 11700 (Pubitemid 44182513)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.31
, pp. 11695-11700
-
-
Zhang, Y.1
Chung, Y.2
Bishop, C.3
Daugherty, B.4
Chute, H.5
Holst, P.6
Kurahara, C.7
Lott, F.8
Sun, N.9
Welcher, A.A.10
Dong, C.11
-
38
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H., Strome S. E., Salomao D. R., Tamura H., Hirano F., Flies D. B., Roche P. C., Lu J., Zhu G., Tamada K., Lennon V. A., Cells E., Chen L., Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion Nature Medicine 2002 8 8 793 800
-
(2002)
Nature Medicine
, vol.8
, Issue.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
Roche, P.C.7
Lu, J.8
Zhu, G.9
Tamada, K.10
Lennon, V.A.11
Cells, E.12
Chen, L.13
-
39
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y., Ishida M., Tanaka Y., Okazaki T., Honjo T., Minato N., Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade Proceedings of the National Academy of Sciences of the United States of America 2002 99 19 12293 12297
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.19
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
40
-
-
65349118810
-
PD-1 signaling in primary T cells
-
Riley J. L., PD-1 signaling in primary T cells Immunological Reviews 2009 229 1 114 125
-
(2009)
Immunological Reviews
, vol.229
, Issue.1
, pp. 114-125
-
-
Riley, J.L.1
-
41
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
DOI 10.1016/S1074-7613(00)80089-8
-
Nishimura H., Nose M., Hiai H., Minato N., Honjo T., Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor Immunity 1999 11 2 141 151 (Pubitemid 29428807)
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
42
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
DOI 10.1126/science.291.5502.319
-
Nishimura H., Okazaki T., Tanaka Y., Nakatani K., Hara M., Matsumori A., Sasayama S., Mizoguchi A., Hiai H., Minato N., Honjo T., Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice Science 2001 291 5502 319 322 (Pubitemid 32096320)
-
(2001)
Science
, vol.291
, Issue.5502
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
Nakatani, K.4
Hara, M.5
Matsumori, A.6
Sasayama, S.7
Mizoguchi, A.8
Hiai, H.9
Minato, N.10
Honjo, T.11
-
43
-
-
0842325739
-
+ T Cells
-
DOI 10.1158/0008-5472.CAN-03-3259
-
Blank C., Brown I., Peterson A. C., Spiotto M., Iwai Y., Honjo T., Gajewski T. F., PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T Cell receptor (TCR) transgenic CD8 + T cells Cancer Research 2004 64 3 1140 1145 (Pubitemid 38176921)
-
(2004)
Cancer Research
, vol.64
, Issue.3
, pp. 1140-1145
-
-
Blank, C.1
Brown, I.2
Peterson, A.C.3
Spiotto, M.4
Iwai, Y.5
Honjo, T.6
Gajewski, T.F.7
-
44
-
-
70349561448
-
PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
-
Zhang L., Gajewski T. F., Kline J., PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model Blood 2009 114 8 1545 1552
-
(2009)
Blood
, vol.114
, Issue.8
, pp. 1545-1552
-
-
Zhang, L.1
Gajewski, T.F.2
Kline, J.3
-
45
-
-
13844294372
-
PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells
-
DOI 10.1093/intimm/dxh194
-
Iwai Y., Terawaki S., Honjo T., PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells International Immunology 2005 17 2 133 144 (Pubitemid 40246578)
-
(2005)
International Immunology
, vol.17
, Issue.2
, pp. 133-144
-
-
Iwai, Y.1
Terawaki, S.2
Honjo, T.3
-
46
-
-
0037815272
-
PD-1 inhibits antiviral immunity at the effector phase in the liver
-
DOI 10.1084/jem.20022235
-
Iwai Y., Terawaki S., Ikegawa M., Okazaki T., Honjo T., PD-1 inhibits antiviral immunity at the effector phase in the liver Journal of Experimental Medicine 2003 198 1 39 50 (Pubitemid 36870184)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.1
, pp. 39-50
-
-
Iwai, Y.1
Terawaki, S.2
Ikegawa, M.3
Okazaki, T.4
Honjo, T.5
-
47
-
-
13444270323
-
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
-
Hirano F., Kaneko K., Tamura H., Dong H., Wang S., Ichikawa M., Rietz C., Flies D. B., Lau J. S., Zhu G., Tamada K., Chen L., Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity Cancer Research 2005 65 3 1089 1096 (Pubitemid 40216472)
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 1089-1096
-
-
Hirano, F.1
Kaneko, K.2
Tamura, H.3
Dong, H.4
Wang, S.5
Ichikawa, M.6
Rietz, C.7
Flies, D.B.8
Lau, J.S.9
Zhu, G.10
Tamada, K.11
Chen, L.12
-
48
-
-
0141953992
-
B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
-
Strome S. E., Dong H., Tamura H., Voss S. G., Flies D. B., Tamada K., Salomao D., Cheville J., Hirano F., Lin W., Kasperbauer J. L., Ballman K. V., Chen L., B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma Cancer Research 2003 63 19 6501 6505 (Pubitemid 37255203)
-
(2003)
Cancer Research
, vol.63
, Issue.19
, pp. 6501-6505
-
-
Strome, S.E.1
Dong, H.2
Tamura, H.3
Voss, S.G.4
Flies, D.B.5
Tamada, K.6
Salomao, D.7
Cheville, J.8
Hirano, F.9
Lin, W.10
Kasperbauer, J.L.11
Ballman, K.V.12
Chen, L.13
-
49
-
-
79953789685
-
Targeting NKT cells and PD-L1 pathway results in augmented anti-tumor responses in a melanoma model
-
Durgan K., Ali M., Warner P., Latchman Y. E., Targeting NKT cells and PD-L1 pathway results in augmented anti-tumor responses in a melanoma model Cancer Immunology, Immunotherapy 2011 60 4 547 558
-
(2011)
Cancer Immunology, Immunotherapy
, vol.60
, Issue.4
, pp. 547-558
-
-
Durgan, K.1
Ali, M.2
Warner, P.3
Latchman, Y.E.4
-
50
-
-
84859104688
-
PD-1 expression on melanA-reactive T-cells increases during progression to metastatic disease
-
Kronig H., Falchner K. J., Odendahl M., Brackertz B., Conrad H., PD-1 expression on melanA-reactive T-cells increases during progression to metastatic disease International Journal of Cancer 2011 130 10 2327 2336
-
(2011)
International Journal of Cancer
, vol.130
, Issue.10
, pp. 2327-2336
-
-
Kronig, H.1
Falchner, K.J.2
Odendahl, M.3
Brackertz, B.4
Conrad, H.5
-
51
-
-
77957723967
-
Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8 + T cell dysfunction in melanoma patients
-
Fourcade J., Sun Z., Benallaoua M., Guillaume P., Luescher I. F., Sander C., Kirkwood J. M., Kuchroo V., Zarour H. M., Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8 + T cell dysfunction in melanoma patients Journal of Experimental Medicine 2010 207 10 2175 2186
-
(2010)
Journal of Experimental Medicine
, vol.207
, Issue.10
, pp. 2175-2186
-
-
Fourcade, J.1
Sun, Z.2
Benallaoua, M.3
Guillaume, P.4
Luescher, I.F.5
Sander, C.6
Kirkwood, J.M.7
Kuchroo, V.8
Zarour, H.M.9
-
52
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer J. R., Drake C. G., Wollner I., Powderly J. D., Picus J., Sharfman W. H., Stankevich E., Pons A., Salay T. M., McMiller T. L., Gilson M. M., Wang C., Selby M., Taube J. M., Anders R., Chen L., Korman A. J., Pardoll D. M., Lowy I., Topalian S. L., Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates Journal of Clinical Oncology 2010 28 19 3167 3175
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.19
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
Stankevich, E.7
Pons, A.8
Salay, T.M.9
McMiller, T.L.10
Gilson, M.M.11
Wang, C.12
Selby, M.13
Taube, J.M.14
Anders, R.15
Chen, L.16
Korman, A.J.17
Pardoll, D.M.18
Lowy, I.19
Topalian, S.L.20
more..
-
53
-
-
49649114804
-
Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R., Rotem-Yehudar R., Slama G., Landes S., Kneller A., Leiba M., Koren-Michowitz M., Shimoni A., Nagler A., Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies Clinical Cancer Research 2008 14 10 3044 3051
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
Landes, S.4
Kneller, A.5
Leiba, M.6
Koren-Michowitz, M.7
Shimoni, A.8
Nagler, A.9
-
54
-
-
77955917121
-
Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies
-
supplement 15s, abstract 2506
-
Sznol M., Powderly J., Smith D., Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies Journal of Clinical Oncology 2010 28 supplement 15s, abstract 2506
-
(2010)
Journal of Clinical Oncology
, vol.28
-
-
Sznol, M.1
Powderly, J.2
Smith, D.3
-
55
-
-
77749279776
-
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
-
Curran M. A., Montalvo W., Yagita H., Allison J. P., PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors Proceedings of the National Academy of Sciences of the United States of America 2010 107 9 4275 4280
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.9
, pp. 4275-4280
-
-
Curran, M.A.1
Montalvo, W.2
Yagita, H.3
Allison, J.P.4
-
57
-
-
33748310638
-
CEACAMs: Their role in physiology and pathophysiology
-
DOI 10.1016/j.ceb.2006.08.008, PII S0955067406001189
-
Kuespert K., Pils S., Hauck C. R., CEACAMs: their role in physiology and pathophysiology Current Opinion in Cell Biology 2006 18 5 565 571 (Pubitemid 44332912)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.5
, pp. 565-571
-
-
Kuespert, K.1
Pils, S.2
Hauck, C.R.3
-
58
-
-
7244254254
-
CEACAM1 enhances invasion and migration of melanocytic and melanoma cells
-
Ebrahimnejad A., Streichert T., Nollau P., Horst A. K., Wagener C., Bamberger A. M., Brmmer J., CEACAM1 enhances invasion and migration of melanocytic and melanoma cells American Journal of Pathology 2004 165 5 1781 1787 (Pubitemid 39435175)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.5
, pp. 1781-1787
-
-
Ebrahimnejad, A.1
Streichert, T.2
Nollau, P.3
Horst, A.K.4
Wagener, C.5
Bamberger, A.-M.6
Brummer, J.7
-
59
-
-
67149131793
-
Protein expression of carcinoembryonic antigen cell adhesion molecules in benign and malignant melanocytic skin lesions
-
Gambichler T., Grothe S., Rotterdam S., Altmeyer P., Kreuter A., Protein expression of carcinoembryonic antigen cell adhesion molecules in benign and malignant melanocytic skin lesions American Journal of Clinical Pathology 2009 131 6 782 787
-
(2009)
American Journal of Clinical Pathology
, vol.131
, Issue.6
, pp. 782-787
-
-
Gambichler, T.1
Grothe, S.2
Rotterdam, S.3
Altmeyer, P.4
Kreuter, A.5
-
60
-
-
0037093211
-
CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease
-
DOI 10.1200/JCO.2002.05.033
-
Thies A., Moll I., Berger J., Wagener C., Brmmer J., Schulze H. J., Brunner G., Schumacher U., CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease Journal of Clinical Oncology 2002 20 10 2530 2536 (Pubitemid 34525740)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.10
, pp. 2530-2536
-
-
Thies, A.1
Moll, I.2
Berger, J.3
Wagener, C.4
Brummer, J.5
Schulze, H.-J.6
Brunner, G.7
Schumacher, U.8
-
61
-
-
0034889826
-
3
-
Brmmer J., Ebrahimnejad A., Flayeh R., Schumacher U., Lning T., Bamberger A. M., Wagener C., cis interaction of the cell adhesion molecule CEACAM1 with itegrin 3 American Journal of Pathology 2001 159 2 537 546 (Pubitemid 32751084)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.2
, pp. 537-546
-
-
Brummer, J.1
Ebrahimnejad, A.2
Flayeh, R.3
Schumacher, U.4
Loning, T.5
Bamberger, A.-M.6
Wagener, C.7
-
62
-
-
0036792506
-
Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions
-
Markel G., Wolf D., Hanna J., Gazit R., Goldman-Wohl D., Lavy Y., Yagel S., Mandelboim O., Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions Journal of Clinical Investigation 2002 110 7 943 953
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.7
, pp. 943-953
-
-
Markel, G.1
Wolf, D.2
Hanna, J.3
Gazit, R.4
Goldman-Wohl, D.5
Lavy, Y.6
Yagel, S.7
Mandelboim, O.8
-
63
-
-
58149302763
-
Dynamic expression of protective CEACAM1 on melanoma cells during specific immune attack
-
Markel G., Seidman R., Cohen Y., Besser M. J., Sinai T. C., Treves A. J., Orenstein A., Berger R., Schachter J., Dynamic expression of protective CEACAM1 on melanoma cells during specific immune attack Immunology 2009 126 2 186 200
-
(2009)
Immunology
, vol.126
, Issue.2
, pp. 186-200
-
-
Markel, G.1
Seidman, R.2
Cohen, Y.3
Besser, M.J.4
Sinai, T.C.5
Treves, A.J.6
Orenstein, A.7
Berger, R.8
Schachter, J.9
-
64
-
-
33750355389
-
Inhibition of human tumor-infiltrating lymphocyte effector functions by the homophilic carcinoembryonic cell adhesion molecule 1 interactions
-
Markel G., Seidman R., Stern N., Cohen-Sinai T., Izhaki O., Katz G., Besser M., Treves A. J., Blumberg R. S., Loewenthal R., Mandelboim O., Orenstein A., Schachter J., Inhibition of human tumor-infiltrating lymphocyte effector functions by the homophilic carcinoembryonic cell adhesion molecule 1 interactions Journal of Immunology 2006 177 9 6062 6071 (Pubitemid 44628821)
-
(2006)
Journal of Immunology
, vol.177
, Issue.9
, pp. 6062-6071
-
-
Markel, G.1
Seidman, R.2
Stern, N.3
Cohen-Sinai, T.4
Izhaki, O.5
Katz, G.6
Besser, M.7
Treves, A.J.8
Blumberg, R.S.9
Loewenthal, R.10
Mandelboim, O.11
Orenstein, A.12
Schachter, J.13
-
65
-
-
10744232230
-
The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients
-
DOI 10.1182/blood-2003-06-2114
-
Markel G., Mussaffi H., Ling K. L., Salio M., Gadola S., Steuer G., Blau H., Achdout H., De Miguel M., Gonen-Gross T., Hanna J., Arnon T. I., Qimron U., Volovitz I., Eisenbach L., Blumberg R. S., Porgador A., Cerundolo V., Mandelboim O., The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients Blood 2004 103 5 1770 1778 (Pubitemid 38268971)
-
(2004)
Blood
, vol.103
, Issue.5
, pp. 1770-1778
-
-
Markel, G.1
Mussaffi, H.2
Ling, K.-L.3
Salio, M.4
Gadola, S.5
Steuer, G.6
Blau, H.7
Achdout, H.8
De Miguel, M.9
Gonen-Gross, T.10
Hanna, J.11
Arnon, T.I.12
Qimron, U.13
Volovitz, I.14
Eisenbach, L.15
Blumberg, R.S.16
Porgador, A.17
Cerundolo, V.18
Mandelboim, O.19
-
66
-
-
4644249118
-
44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells
-
Markel G., Gruda R., Achdout H., Katz G., Nechama M., Blumberg R. S., Kammerer R., Zimmermann W., Mandelboim O., The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells Journal of Immunology 2004 173 6 3732 3739 (Pubitemid 39280734)
-
(2004)
Journal of Immunology
, vol.173
, Issue.6
, pp. 3732-3739
-
-
Markel, G.1
Gruda, R.2
Achdout, H.3
Katz, G.4
Nechama, M.5
Blumberg, R.S.6
Kammerer, R.7
Zimmermann, W.8
Mandelboim, O.9
-
67
-
-
26444529548
-
The involvement of NK cells in ankylosing spondylitis
-
DOI 10.1093/intimm/dxh270
-
Azuz-Lieberman N., Markel G., Mizrahi S., Gazit R., Hanna J., Achdout H., Gruda R., Katz G., Arnon T. I., Battat S., Zamir E., Adawi M., Mader R., Mandelboim O., The involvement of NK cells in ankylosing spondylitis International Immunology 2005 17 7 837 845 (Pubitemid 41417951)
-
(2005)
International Immunology
, vol.17
, Issue.7
, pp. 837-845
-
-
Azuz-Lieberman, N.1
Markel, G.2
Mizrahi, S.3
Gazit, R.4
Hanna, J.5
Achdout, H.6
Gruda, R.7
Katz, G.8
Arnon, T.I.9
Battat, S.10
Zamir, E.11
Adawi, M.12
Mader, R.13
Mandelboim, O.14
-
68
-
-
71849114335
-
Systemic dysregulation of CEACAM1 in melanoma patients
-
Markel G., Ortenberg R., Seidman R., Sapoznik S., Koren-Morag N., Besser M. J., Bar J., Shapira R., Kubi A., Nardini G., Tessone A., Treves A. J., Winkler E., Orenstein A., Schachter J., Systemic dysregulation of CEACAM1 in melanoma patients Cancer Immunology, Immunotherapy 2010 59 2 215 230
-
(2010)
Cancer Immunology, Immunotherapy
, vol.59
, Issue.2
, pp. 215-230
-
-
Markel, G.1
Ortenberg, R.2
Seidman, R.3
Sapoznik, S.4
Koren-Morag, N.5
Besser, M.J.6
Bar, J.7
Shapira, R.8
Kubi, A.9
Nardini, G.10
Tessone, A.11
Treves, A.J.12
Winkler, E.13
Orenstein, A.14
Schachter, J.15
-
69
-
-
0037087297
-
CD66a interactions between human melanoma and NK cells: A novel class I MHC-independent inhibitory mechanism of cytotoxicity
-
Markel G., Lieberman N., Katz G., Arnon T. I., Lotem M., Drize O., Blumberg R. S., Bar-Haim E., Mader R., Eisenbach L., Mandelboim O., CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity Journal of Immunology 2002 168 6 2803 2810 (Pubitemid 34211659)
-
(2002)
Journal of Immunology
, vol.168
, Issue.6
, pp. 2803-2810
-
-
Markel, G.1
Lieberman, N.2
Katz, G.3
Arnon, T.I.4
Lotem, M.5
Drize, O.6
Blumberg, R.S.7
Bar-Haim, E.8
Mader, R.9
Eisenbach, L.10
Mandelboim, O.11
-
70
-
-
4444252225
-
Biological function of the soluble CEACAM1 protein and implications in TAP2-deficient patients
-
DOI 10.1002/eji.200425021
-
Markel G., Achdout H., Katz G., Ling K. L., Salio M., Gruda R., Gazit R., Mizrahi S., Hanna J., Gonen-Gross T., Arnon T. I., Lieberman N., Stren N., Nachmias B., Blumberg R. S., Steuer G., Blau H., Cerundolo V., Mussaffi H., Mandelboim O., Biological function of the soluble CEACAM1 protein and implications in TAP2-deficient patients European Journal of Immunology 2004 34 8 2138 2148 (Pubitemid 39256095)
-
(2004)
European Journal of Immunology
, vol.34
, Issue.8
, pp. 2138-2148
-
-
Markel, G.1
Achdout, H.2
Katz, G.3
Ling, K.-L.4
Salio, M.5
Gruda, R.6
Gazit, R.7
Mizrahi, S.8
Hanna, J.9
Gonen-Gross, T.10
Arnon, T.I.11
Lieberman, N.12
Stren, N.13
Nachmias, B.14
Blumberg, R.S.15
Steuer, G.16
Blau, H.17
Cerundolo, V.18
Mussaffi, H.19
Mandelboim, O.20
more..
-
71
-
-
44449083973
-
Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70
-
Chen Z., Chen L., Qiao S. W., Nagaishi T., Blumberg R. S., Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70 Journal of Immunology 2008 180 9 6085 6093
-
(2008)
Journal of Immunology
, vol.180
, Issue.9
, pp. 6085-6093
-
-
Chen, Z.1
Chen, L.2
Qiao, S.W.3
Nagaishi, T.4
Blumberg, R.S.5
-
72
-
-
33846249299
-
SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms
-
DOI 10.1016/j.immuni.2006.08.026, PII S1074761306004705
-
Nagaishi T., Pao L., Lin S. H., Iijima H., Kaser A., Qiao S. W., Chen Z., Glickman J., Najjar S. M., Nakajima A., Neel B. G., Blumberg R. S., SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms Immunity 2006 25 5 769 781 (Pubitemid 46107284)
-
(2006)
Immunity
, vol.25
, Issue.5
, pp. 769-781
-
-
Nagaishi, T.1
Pao, L.2
Lin, S.-H.3
Iijima, H.4
Kaser, A.5
Qiao, S.-W.6
Chen, Z.7
Glickman, J.8
Najjar, S.M.9
Nakajima, A.10
Neel, B.G.11
Blumberg, R.S.12
-
73
-
-
18944379881
-
Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1
-
Stern N., Markel G., Arnon T. I., Gruda R., Wong H., Gray-Owen S. D., Mandelboim O., Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1 Journal of Immunology 2005 174 11 6692 6701 (Pubitemid 40705631)
-
(2005)
Journal of Immunology
, vol.174
, Issue.11
, pp. 6692-6701
-
-
Stern, N.1
Markel, G.2
Arnon, T.I.3
Gruda, R.4
Wong, H.5
Gray-Owen, S.D.6
Mandelboim, O.7
-
74
-
-
0029887620
-
Biliary glycoprotein (BGP) expression on T cells and on a natural-killer-cell sub-population
-
DOI 10.1002/(SICI)1097-0215 (19960315) 65:6<740:: AID-IJC5>3.0. CO;2-Z
-
Moller M. J., Kammerer R., Grunert F., von Kleist S., Biliary glycoprotein (BGP) expression on T-cells and on a natural-killer-cell sub-population International Journal of Cancer 1996 65 6 740 745 (Pubitemid 26127751)
-
(1996)
International Journal of Cancer
, vol.65
, Issue.6
, pp. 740-745
-
-
Moller, M.J.1
Kammerer, R.2
Grunert, F.3
Von Kleist, S.4
-
75
-
-
84862564583
-
Novel immunutherapy for malignant melanoma with a monoclonal antibody that blocks CEACAM1 homophilic interactions
-
In press
-
Ortenberg R., Sapir Y., Raz L., Hershkovitz L., Arav A. B., Novel immunutherapy for malignant melanoma with a monoclonal antibody that blocks CEACAM1 homophilic interactions. Molecular Cancer Therapeutics. In press
-
Molecular Cancer Therapeutics
-
-
Ortenberg, R.1
Sapir, Y.2
Raz, L.3
Hershkovitz, L.4
Arav, A.B.5
-
76
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
DOI 10.1200/JCO.2005.00.240
-
Dudley M. E., Wunderlich J. R., Yang J. C., Sherry R. M., Topalian S. L., Restifo N. P., Royal R. E., Kammula U., White D. E., Mavroukakis S. A., Rogers L. J., Gracia G. J., Jones S. A., Mangiameli D. P., Pelletier M. M., Gea-Banacloche J., Robinson M. R., Berman D. M., Filie A. C., Abati A., Rosenberg S. A., Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma Journal of Clinical Oncology 2005 23 10 2346 2357 (Pubitemid 46218728)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.10
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
Sherry, R.M.4
Topalian, S.L.5
Restifo, N.P.6
Royal, R.E.7
Kammula, U.8
White, D.E.9
Mavroukakis, S.A.10
Rogers, L.J.11
Gracia, G.J.12
Jones, S.A.13
Mangiameli, D.P.14
Pelletier, M.M.15
Gea-Banacloche, J.16
Robinson, M.R.17
Berman, D.M.18
Filie, A.C.19
Abati, A.20
Rosenberg, S.A.21
more..
-
77
-
-
55949125601
-
Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
-
Dudley M. E., Yang J. C., Sherry R., Hughes M. S., Royal R., Kammula U., Robbins P. F., Huang J., Citrin D. E., Leitman S. F., Wunderlich J., Restifo N. P., Thomasian A., Downey S. G., Smith F. O., Klapper J., Morton K., Laurencot C., White D. E., Rosenberg S. A., Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens Journal of Clinical Oncology 2008 26 32 5233 5239
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.32
, pp. 5233-5239
-
-
Dudley, M.E.1
Yang, J.C.2
Sherry, R.3
Hughes, M.S.4
Royal, R.5
Kammula, U.6
Robbins, P.F.7
Huang, J.8
Citrin, D.E.9
Leitman, S.F.10
Wunderlich, J.11
Restifo, N.P.12
Thomasian, A.13
Downey, S.G.14
Smith, F.O.15
Klapper, J.16
Morton, K.17
Laurencot, C.18
White, D.E.19
Rosenberg, S.A.20
more..
-
78
-
-
77951714425
-
Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients
-
Besser M. J., Shapira-Frommer R., Treves A. J., Zippel D., Itzhaki O., Hershkovitz L., Levy D., Kubi A., Hovav E., Chermoshniuk N., Shalmon B., Hardan I., Catane R., Markel G., Apter S., Ben-Nun A., Kuchuk I., Shimoni A., Nagler A., Schachter J., Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients Clinical Cancer Research 2010 16 9 2646 2655
-
(2010)
Clinical Cancer Research
, vol.16
, Issue.9
, pp. 2646-2655
-
-
Besser, M.J.1
Shapira-Frommer, R.2
Treves, A.J.3
Zippel, D.4
Itzhaki, O.5
Hershkovitz, L.6
Levy, D.7
Kubi, A.8
Hovav, E.9
Chermoshniuk, N.10
Shalmon, B.11
Hardan, I.12
Catane, R.13
Markel, G.14
Apter, S.15
Ben-Nun, A.16
Kuchuk, I.17
Shimoni, A.18
Nagler, A.19
Schachter, J.20
more..
-
79
-
-
0028304484
-
In vitro predictors of therapeutic response in melanoma patients receiving tumor-infiltrating lymphocytes and interleukin-2
-
Schwartzentruber D. J., Hom S. S., Dadmarz R., White D. E., Yannelli J. R., Steinberg S. M., Rosenberg S. A., Topalian S. L., In vitro predictors of therapeutic response in melanoma patients receiving tumor-infiltrating lymphocytes and interleukin-2 Journal of Clinical Oncology 1994 12 7 1475 1483 (Pubitemid 24206248)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.7
, pp. 1475-1483
-
-
Schwartzentruber, D.J.1
Hom, S.S.2
Dadmarz, R.3
White, D.E.4
Yannelli, J.R.5
Steinberg, S.M.6
Rosenberg, S.A.7
Topalian, S.L.8
-
80
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
DOI 10.1126/science.1129003
-
Morgan R. A., Dudley M. E., Wunderlich J. R., Hughes M. S., Yang J. C., Sherry R. M., Royal R. E., Topalan S. L., Kammula U. S., Restifo N. P., Zheng Z., Nahvi A., De Vries C. R., Rogers-Freezer L. J., Mavroukakis S. A., Rosenberg S. A., Cancer regression in patients after transfer of genetically engineered lymphocytes Science 2006 314 5796 126 129 (Pubitemid 44547756)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
Topalian, S.L.8
Kammula, U.S.9
Restifo, N.P.10
Zheng, Z.11
Nahvi, A.12
De Vries, C.R.13
Rogers-Freezer, L.J.14
Mavroukakis, S.A.15
Rosenberg, S.A.16
-
81
-
-
70149114880
-
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
-
Johnson L. A., Morgan R. A., Dudley M. E., Cassard L., Yang J. C., Hughes M. S., Kammula U. S., Royal R. E., Sherry R. M., Wunderlich J. R., Lee C. C. R., Restifo N. P., Schwarz S. L., Cogdill A. P., Bishop R. J., Kim H., Brewer C. C., Rudy S. F., VanWaes C., Davis J. L., Mathur A., Ripley R. T., Nathan D. A., Laurencot C. M., Rosenberg S. A., Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen Blood 2009 114 3 535 546
-
(2009)
Blood
, vol.114
, Issue.3
, pp. 535-546
-
-
Johnson, L.A.1
Morgan, R.A.2
Dudley, M.E.3
Cassard, L.4
Yang, J.C.5
Hughes, M.S.6
Kammula, U.S.7
Royal, R.E.8
Sherry, R.M.9
Wunderlich, J.R.10
Lee, C.C.R.11
Restifo, N.P.12
Schwarz, S.L.13
Cogdill, A.P.14
Bishop, R.J.15
Kim, H.16
Brewer, C.C.17
Rudy, S.F.18
Vanwaes, C.19
Davis, J.L.20
Mathur, A.21
Ripley, R.T.22
Nathan, D.A.23
Laurencot, C.M.24
Rosenberg, S.A.25
more..
-
82
-
-
79958023047
-
Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy
-
Ramos C. A., Dotti G., Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy Expert Opinion on Biological Therapy 2011 11 7 855 873
-
(2011)
Expert Opinion on Biological Therapy
, vol.11
, Issue.7
, pp. 855-873
-
-
Ramos, C.A.1
Dotti, G.2
-
83
-
-
70349439277
-
Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells
-
Yvon E., del Vecchio M., Savoldo B., Hoyos V., Dutour A., Anichini A., Dotti G., Brenner M. K., Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells Clinical Cancer Research 2009 15 18 5852 5860
-
(2009)
Clinical Cancer Research
, vol.15
, Issue.18
, pp. 5852-5860
-
-
Yvon, E.1
Del Vecchio, M.2
Savoldo, B.3
Hoyos, V.4
Dutour, A.5
Anichini, A.6
Dotti, G.7
Brenner, M.K.8
-
84
-
-
78349255049
-
Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses
-
Peng W., Ye Y., Rabinovich B. A., Liu C., Lou Y., Zhang M., Whittington M., Yang Y., Overwijk W. W., Lizée G., Hwu P., Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses Clinical Cancer Research 2010 16 22 5458 5468
-
(2010)
Clinical Cancer Research
, vol.16
, Issue.22
, pp. 5458-5468
-
-
Peng, W.1
Ye, Y.2
Rabinovich, B.A.3
Liu, C.4
Lou, Y.5
Zhang, M.6
Whittington, M.7
Yang, Y.8
Overwijk, W.W.9
Lizée, G.10
Hwu, P.11
-
86
-
-
77957273591
-
Improved endpoints for cancer immunotherapy trials
-
Hoos A., Eggermont A. M., Janetzki S., Hodi F., Ibrahim R., Anderson A., Humphrey R., Blumenstein B., Old L., Wolchok J., Improved endpoints for cancer immunotherapy trials Journal of the National Cancer Institute 2010 102 18 1388 1397
-
(2010)
Journal of the National Cancer Institute
, vol.102
, Issue.18
, pp. 1388-1397
-
-
Hoos, A.1
Eggermont, A.M.2
Janetzki, S.3
Hodi, F.4
Ibrahim, R.5
Anderson, A.6
Humphrey, R.7
Blumenstein, B.8
Old, L.9
Wolchok, J.10
-
87
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff P., Higano C., Shore N., Berger E. R., Small E. J., Penson D. F., Redfern C. H., Ferrari A. C., Dreicer R., Sims R. B., Xu Y., Frohlich M. W., Schellhammer P. F., Sipuleucel-T immunotherapy for castration-resistant prostate cancer The New England Journal of Medicine 2010 363 5 411 422
-
(2010)
The New England Journal of Medicine
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.1
Higano, C.2
Shore, N.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
Redfern, C.H.7
Ferrari, A.C.8
Dreicer, R.9
Sims, R.B.10
Xu, Y.11
Frohlich, M.W.12
Schellhammer, P.F.13
-
88
-
-
84859158384
-
Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
-
Topalian S. L., Drake C. G., Pardoll D. M., Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity Current Opinion in Immunology 2012 24 2 207 212
-
(2012)
Current Opinion in Immunology
, vol.24
, Issue.2
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
|