-
1
-
-
84902810053
-
In pursuit of design principles of regulatory sequences
-
Levo M, Segal E. In pursuit of design principles of regulatory sequences. Nature Rev Gen. 2014; 15(7):453-68.
-
(2014)
Nature Rev Gen
, vol.15
, Issue.7
, pp. 453-468
-
-
Levo, M.1
Segal, E.2
-
2
-
-
84908049845
-
Viewing Protein Fitness Landscapes Through a Next-Gen Lens
-
Boucher JI, Cote P, Flynn J, Jiang L, Laban A, Mishra P, et al. Viewing Protein Fitness Landscapes Through a Next-Gen Lens. Genetics. 2014; 198(2):461-471.
-
(2014)
Genetics
, vol.198
, Issue.2
, pp. 461-471
-
-
Boucher, J.I.1
Cote, P.2
Flynn, J.3
Jiang, L.4
Laban, A.5
Mishra, P.6
-
3
-
-
84902775598
-
Empirical fitness landscapes and the predictability of evolution
-
de Visser JAGM, Krug J. Empirical fitness landscapes and the predictability of evolution. Nature Rev Gen. 2014; 15(7):480-90.
-
(2014)
Nature Rev Gen
, vol.15
, Issue.7
, pp. 480-490
-
-
de Visser, J.A.G.M.1
Krug, J.2
-
4
-
-
77952706498
-
Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence
-
Kinney JB, Murugan A, Callan CG, Cox EC. Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence. Proc Natl Acad Sci USA. 2010; 107(20):9158-63.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.20
, pp. 9158-9163
-
-
Kinney, J.B.1
Murugan, A.2
Callan, C.G.3
Cox, E.C.4
-
5
-
-
84862002321
-
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
-
Sharon E, Kalma Y, Sharp A, Raveh-Sadka T, Levo M, Zeevi D, et al. Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. Nature Biotechnol. 2012; 30(6):521-30.
-
(2012)
Nature Biotechnol
, vol.30
, Issue.6
, pp. 521-530
-
-
Sharon, E.1
Kalma, Y.2
Sharp, A.3
Raveh-Sadka, T.4
Zeevi, D.5
-
6
-
-
84882777421
-
Composability of regulatory sequences controlling transcription and translation in Escherichia coli
-
Kosuri S, Goodman DB, Cambray G, Mutalik VK, Gao Y, Arkin AP, et al. Composability of regulatory sequences controlling transcription and translation in Escherichia coli. Proc Natl Acad Sci USA. 2013; 110(34):14024-9.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.34
, pp. 14024-14029
-
-
Kosuri, S.1
Goodman, D.B.2
Cambray, G.3
Mutalik, V.K.4
Gao, Y.5
Arkin, A.P.6
-
7
-
-
84907338120
-
Quantitative analysis of mammalian translation initiation sites by FACS-seq
-
Noderer WL, Flockhart RJ, Bhaduri A, Diaz de Arce AJ, Zhang J, Khavari PA, et al. Quantitative analysis of mammalian translation initiation sites by FACS-seq. Mol Syst Biol. 2014; 10(8):748.
-
(2014)
Mol Syst Biol
, vol.10
, Issue.8
, pp. 748
-
-
Noderer, W.L.1
Flockhart, R.J.2
Bhaduri, A.3
Diaz de Arce, A.J.4
Zhang, J.5
Khavari, P.A.6
-
8
-
-
84907527856
-
Probing the effect of promoters on noise in gene expression using thousands of designed sequences
-
Sharon E, Dijk Dv, Kalma Y, Keren L, Manor O, Yakhini Z, et al. Probing the effect of promoters on noise in gene expression using thousands of designed sequences. Genome Res. 2014; 24(10):1698-706.
-
(2014)
Genome Res
, vol.24
, Issue.10
, pp. 1698-1706
-
-
Sharon, E.1
Dijk, D.2
Kalma, Y.3
Keren, L.4
Manor, O.5
Yakhini, Z.6
-
9
-
-
84925283037
-
Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity
-
Peterman N, Lavi-Itzkovitz A, Levine E. Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity. Nucleic Acids Res. 2014; 42(19):12177-88.
-
(2014)
Nucleic Acids Res
, vol.42
, Issue.19
, pp. 12177-12188
-
-
Peterman, N.1
Lavi-Itzkovitz, A.2
Levine, E.3
-
10
-
-
70349634435
-
Quantitative phenotyping via deep barcode sequencing
-
Smith AM, Heisler LE, Mellor J, Kaper F, Thompson MJ, Chee M, et al. Quantitative phenotyping via deep barcode sequencing. Genome Res. 2009; 19(10):1836-42.
-
(2009)
Genome Res
, vol.19
, Issue.10
, pp. 1836-1842
-
-
Smith, A.M.1
Heisler, L.E.2
Mellor, J.3
Kaper, F.4
Thompson, M.J.5
Chee, M.6
-
11
-
-
79956357160
-
Experimental illumination of a fitness landscape
-
Hietpas RT, Jensen JD, Bolon DNA. Experimental illumination of a fitness landscape. Proc Natl Acad Sci. 2011; 108(19):201016024.
-
(2011)
Proc Natl Acad Sci
, vol.108
, Issue.19
, pp. 201016024
-
-
Hietpas, R.T.1
Jensen, J.D.2
Bolon, D.N.A.3
-
12
-
-
84906217475
-
Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes
-
Melnikov A, Rogov P, Wang L, Gnirke A, Mikkelsen TS. Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes. Nucl Acids Res. 2014; 42(14):e112.
-
(2014)
Nucl Acids Res
, vol.42
, Issue.14
, pp. e112
-
-
Melnikov, A.1
Rogov, P.2
Wang, L.3
Gnirke, A.4
Mikkelsen, T.S.5
-
13
-
-
84922384542
-
A Systematic Survey of an Intragenic Epistatic Landscape
-
Bank C, Hietpas RT, Jensen JD, Bolon DNA. A Systematic Survey of an Intragenic Epistatic Landscape. Mol Biol Evol. 2015; 32(1):229-38.
-
(2015)
Mol Biol Evol
, vol.32
, Issue.1
, pp. 229-238
-
-
Bank, C.1
Hietpas, R.T.2
Jensen, J.D.3
Bolon, D.N.A.4
-
14
-
-
84923321398
-
Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase
-
Stiffler M, Hekstra D, Ranganathan R. Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase. Cell. 2015; 160(5):882-92.
-
(2015)
Cell
, vol.160
, Issue.5
, pp. 882-892
-
-
Stiffler, M.1
Hekstra, D.2
Ranganathan, R.3
-
15
-
-
76049090891
-
Analysis of a complete DNA-protein affinity landscape
-
Rowe W, Platt M, Wedge DC, Day PJ, Kell DB, Knowles J. Analysis of a complete DNA-protein affinity landscape. J Royal Soc Interface/Royal Soc. 2010; 7(44):397-408.
-
(2010)
J Royal Soc Interface/Royal Soc
, vol.7
, Issue.44
, pp. 397-408
-
-
Rowe, W.1
Platt, M.2
Wedge, D.C.3
Day, P.J.4
Kell, D.B.5
Knowles, J.6
-
16
-
-
77956338533
-
High-resolution mapping of protein sequence-function relationships
-
Fowler DM, Araya CL, Fleishman SJ, Kellogg EH, Stephany JJ, Baker D, et al. High-resolution mapping of protein sequence-function relationships. Nature Methods. 2010; 7(9):741-6.
-
(2010)
Nature Methods
, vol.7
, Issue.9
, pp. 741-746
-
-
Fowler, D.M.1
Araya, C.L.2
Fleishman, S.J.3
Kellogg, E.H.4
Stephany, J.J.5
Baker, D.6
-
17
-
-
77957963240
-
Rapid Construction of Empirical RNA Fitness Landscapes
-
Pitt JN, Ferré-D'Amaré AR. Rapid Construction of Empirical RNA Fitness Landscapes. Science. 2010; 330(6002):376-9.
-
(2010)
Science
, vol.330
, Issue.6002
, pp. 376-379
-
-
Pitt, J.N.1
Ferré-D'Amaré, A.R.2
-
18
-
-
84867644046
-
A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function
-
Araya CL, Fowler DM, Chen W, Muniez I, Kelly JW, Fields S. A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function. Proc Natl Acad Sci. 2012; 109(42):16858-63.
-
(2012)
Proc Natl Acad Sci
, vol.109
, Issue.42
, pp. 16858-16863
-
-
Araya, C.L.1
Fowler, D.M.2
Chen, W.3
Muniez, I.4
Kelly, J.W.5
Fields, S.6
-
19
-
-
84901804745
-
Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes
-
Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, et al. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nature Biotechnol. 2014; 32(6):562-8.
-
(2014)
Nature Biotechnol
, vol.32
, Issue.6
, pp. 562-568
-
-
Buenrostro, J.D.1
Araya, C.L.2
Chircus, L.M.3
Layton, C.J.4
Chang, H.Y.5
Snyder, M.P.6
-
20
-
-
84905217368
-
Deep mutational scanning: a new style of protein science
-
Fowler DM, Fields S. Deep mutational scanning: a new style of protein science. Nature Methods. 2014; 11(8):801-7.
-
(2014)
Nature Methods
, vol.11
, Issue.8
, pp. 801-807
-
-
Fowler, D.M.1
Fields, S.2
-
21
-
-
71849118573
-
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
-
Patwardhan RP, Lee C, Litvin O, Young DL, Pe'er D, Shendure J. High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis. 27. 2009; 12:1173-75.
-
(2009)
27
, vol.12
, pp. 1173-1175
-
-
Patwardhan, R.P.1
Lee, C.2
Litvin, O.3
Young, D.L.4
Pe'er, D.5
Shendure, J.6
-
22
-
-
84863230316
-
Massively parallel functional dissection of mammalian enhancers in vivo
-
Patwardhan RP, Hiatt JB, Witten DM, Kim MJ, Smith RP, May D, et al. Massively parallel functional dissection of mammalian enhancers in vivo. Nature Biotechnol. 2012; 30(3):265-70.
-
(2012)
Nature Biotechnol
, vol.30
, Issue.3
, pp. 265-270
-
-
Patwardhan, R.P.1
Hiatt, J.B.2
Witten, D.M.3
Kim, M.J.4
Smith, R.P.5
May, D.6
-
23
-
-
84863229330
-
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay
-
Melnikov A, Murugan A, Zhang X, Tesileanu T, Wang L, Rogov P, et al. Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nature Biotechnol. 2012; 30(3):271-7.
-
(2012)
Nature Biotechnol
, vol.30
, Issue.3
, pp. 271-277
-
-
Melnikov, A.1
Murugan, A.2
Zhang, X.3
Tesileanu, T.4
Wang, L.5
Rogov, P.6
-
24
-
-
84869853147
-
Complex effects of nucleotide variants in a mammalian cis-regulatory element
-
Kwasnieski JC, Mogno I, Myers CA, Corbo JC, Cohen BA. Complex effects of nucleotide variants in a mammalian cis-regulatory element. Proc Natl Acad Sci. 2012; 109(47):19498-503.
-
(2012)
Proc Natl Acad Sci
, vol.109
, Issue.47
, pp. 19498-19503
-
-
Kwasnieski, J.C.1
Mogno, I.2
Myers, C.A.3
Corbo, J.C.4
Cohen, B.A.5
-
25
-
-
84874381107
-
Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq
-
Arnold CD, Gerlach D, Stelzer C, Boryń LM, Rath M, Stark A. Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq. Science. 2013; 339(6123):1074-77.
-
(2013)
Science
, vol.339
, Issue.6123
, pp. 1074-1077
-
-
Arnold, C.D.1
Gerlach, D.2
Stelzer, C.3
Rath, M.4
Stark, A.5
Boryń, LM6
-
26
-
-
84907257107
-
Saturation editing of genomic regions by multiplex homology-directed repair
-
Findlay GM, Boyle EA, Hause RJ, Klein JC, Shendure J. Saturation editing of genomic regions by multiplex homology-directed repair. Nature. 2014; 513(7516):120-3.
-
(2014)
Nature
, vol.513
, Issue.7516
, pp. 120-123
-
-
Findlay, G.M.1
Boyle, E.A.2
Hause, R.J.3
Klein, J.C.4
Shendure, J.5
-
27
-
-
84923119852
-
High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions
-
Krebs AR, Dessus-Babus S, Burger L, Schübeler D. High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions. eLife. 2014; 3:e04094.
-
(2014)
eLife
, vol.3
, pp. e04094
-
-
Krebs, A.R.1
Dessus-Babus, S.2
Burger, L.3
Schübeler, D.4
-
28
-
-
84897481674
-
Comparison of the theoretical and real-world evolutionary potential of a genetic circuit
-
Razo-Mejia M, Boedicker JQ, Jones D, DeLuna A, Kinney JB, Phillips R. Comparison of the theoretical and real-world evolutionary potential of a genetic circuit. Physical biol. 2014; 11(2):026005.
-
(2014)
Physical biol
, vol.11
, Issue.2
, pp. 026005
-
-
Razo-Mejia, M.1
Boedicker, J.Q.2
Jones, D.3
DeLuna, A.4
Kinney, J.B.5
Phillips, R.6
-
29
-
-
84899692444
-
Function-based identification of mammalian enhancers using site-specific integration
-
Dickel DE, Zhu Y, Nord AS, Wylie JN, Akiyama JA, Afzal V, et al. Function-based identification of mammalian enhancers using site-specific integration. Nature Methods. 2014; 11(5):566-71.
-
(2014)
Nature Methods
, vol.11
, Issue.5
, pp. 566-571
-
-
Dickel, D.E.1
Zhu, Y.2
Nord, A.S.3
Wylie, J.N.4
Akiyama, J.A.5
Afzal, V.6
-
30
-
-
84899670369
-
FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells
-
Murtha M, Tokcaer-Keskin Z, Tang Z, Strino F, Chen X, Wang Y, et al. FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells. Nature Methods. 2014; 11(5):559-65.
-
(2014)
Nature Methods
, vol.11
, Issue.5
, pp. 559-565
-
-
Murtha, M.1
Tokcaer-Keskin, Z.2
Tang, Z.3
Strino, F.4
Chen, X.5
Wang, Y.6
-
31
-
-
84880652281
-
Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast
-
Dvir S, Velten L, Sharon E, Zeevi D, Carey LB, Weinberger A, et al. Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast. Proc Natl Acad Sci USA. 2013; 110(30):E2792-2801.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.30
, pp. E2792-2801
-
-
Dvir, S.1
Velten, L.2
Sharon, E.3
Zeevi, D.4
Carey, L.B.5
Weinberger, A.6
-
32
-
-
84898048208
-
Systematic identification of regulatory elements in conserved 3' UTRs of human transcripts
-
Oikonomou P, Goodarzi H, Tavazoie S. Systematic identification of regulatory elements in conserved 3' UTRs of human transcripts. Cell Reports. 2014; 7(1):281-92.
-
(2014)
Cell Reports
, vol.7
, Issue.1
, pp. 281-292
-
-
Oikonomou, P.1
Goodarzi, H.2
Tavazoie, S.3
-
33
-
-
84930350341
-
Systematic Dissection of the Sequence Determinants of Gene 3' End Mediated Expression Control
-
Shalem O, Sharon E, Lubliner S, Regev I, Lotan-Pompan M, Yakhini Z, et al. Systematic Dissection of the Sequence Determinants of Gene 3' End Mediated Expression Control. PLoS Genet. 2015; 11(4):e1005147.
-
(2015)
PLoS Genet
, vol.11
, Issue.4
, pp. e1005147
-
-
Shalem, O.1
Sharon, E.2
Lubliner, S.3
Regev, I.4
Lotan-Pompan, M.5
Yakhini, Z.6
-
35
-
-
84877983042
-
Massive functional mapping of a 5'UTR by saturation mutagenesis, phenotypic sorting and deep sequencing
-
Holmqvist E, Reimegård J, Wagner EGH. Massive functional mapping of a 5'UTR by saturation mutagenesis, phenotypic sorting and deep sequencing. Nucleic Acids Res. 2013; 41(12):e122.
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.12
, pp. e122
-
-
Holmqvist, E.1
Reimegård, J.2
Wagner, E.G.H.3
-
36
-
-
84868365613
-
The spatial architecture of protein function and adaptation
-
McLaughlin RN, Poelwijk FJ, Raman A, Gosal WS, Ranganathan R. The spatial architecture of protein function and adaptation. Nature. 2012; 491(7422):138-42.
-
(2012)
Nature
, vol.491
, Issue.7422
, pp. 138-142
-
-
McLaughlin, R.N.1
Poelwijk, F.J.2
Raman, A.3
Gosal, W.S.4
Ranganathan, R.5
-
37
-
-
84862025262
-
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
-
Whitehead TA, Chevalier A, Song Y, Dreyfus C, Fleishman SJ, De Mattos C, et al. Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nature Biotechnol. 2012; 30(6):543-8.
-
(2012)
Nature Biotechnol
, vol.30
, Issue.6
, pp. 543-548
-
-
Whitehead, T.A.1
Chevalier, A.2
Song, Y.3
Dreyfus, C.4
Fleishman, S.J.5
De Mattos, C.6
-
38
-
-
84886302057
-
Causes and effects of N-terminal codon bias in bacterial genes
-
Goodman DB, Church GM, Kosuri S. Causes and effects of N-terminal codon bias in bacterial genes. Science New York, NY. 2013; 342(6157):475-9.
-
(2013)
Science New York, NY
, vol.342
, Issue.6157
, pp. 475-479
-
-
Goodman, D.B.1
Church, G.M.2
Kosuri, S.3
-
39
-
-
84922439802
-
Pervasive degeneracy and epistasis in a protein-protein interface
-
Podgornaia AI, Laub MT. Pervasive degeneracy and epistasis in a protein-protein interface. Science. 2015; 347(6222):673-7.
-
(2015)
Science
, vol.347
, Issue.6222
, pp. 673-677
-
-
Podgornaia, A.I.1
Laub, M.T.2
-
40
-
-
84900841403
-
Massively parallel functional annotation of 3' untranslated regions
-
Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. Massively parallel functional annotation of 3' untranslated regions. Nature Biotechnol. 2014; 32(4):387-91.
-
(2014)
Nature Biotechnol
, vol.32
, Issue.4
, pp. 387-391
-
-
Zhao, W.1
Pollack, J.L.2
Blagev, D.P.3
Zaitlen, N.4
McManus, M.T.5
Erle, D.J.6
-
41
-
-
84881442078
-
Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos
-
Gisselbrecht SS, Barrera LA, Porsch M, Aboukhalil A, Estep Iii PW, Vedenko A, et al. Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos. Nature Methods. 2013; 10(8):774-80.
-
(2013)
Nature Methods
, vol.10
, Issue.8
, pp. 774-780
-
-
Gisselbrecht, S.S.1
Barrera, L.A.2
Porsch, M.3
Aboukhalil, A.4
Estep Iii, P.W.5
Vedenko, A.6
-
42
-
-
84860595791
-
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture
-
Rohland N, Reich D. Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture. Genome Res. 2012; 22(5):939-46.
-
(2012)
Genome Res
, vol.22
, Issue.5
, pp. 939-946
-
-
Rohland, N.1
Reich, D.2
-
43
-
-
84899696363
-
Large-scale de novo DNA synthesis: technologies and applications
-
Kosuri S, Church GM. Large-scale de novo DNA synthesis: technologies and applications. Nature Methods. 2014; 11(5):499-507.
-
(2014)
Nature Methods
, vol.11
, Issue.5
, pp. 499-507
-
-
Kosuri, S.1
Church, G.M.2
-
44
-
-
84923848137
-
Massively parallel single-amino-acid mutagenesis
-
Kitzman JO, Starita LM, Lo RS, Fields S, Shendure J. Massively parallel single-amino-acid mutagenesis. Nature Methods. 2015; 12(3):203-6.
-
(2015)
Nature Methods
, vol.12
, Issue.3
, pp. 203-206
-
-
Kitzman, J.O.1
Starita, L.M.2
Lo, R.S.3
Fields, S.4
Shendure, J.5
-
46
-
-
84861899273
-
Universal Protein Fluctuations in Populations of Microorganisms
-
Salman H, Brenner N, Tung Ck, Elyahu N, Stolovicki E, Moore L, et al. Universal Protein Fluctuations in Populations of Microorganisms. Physical Review Lett. 2012; 108(23):238105.
-
(2012)
Physical Review Lett
, vol.108
, Issue.23
, pp. 238105
-
-
Salman, H.1
Brenner, N.2
Tung, C.3
Elyahu, N.4
Stolovicki, E.5
Moore, L.6
-
47
-
-
0037119587
-
Stochastic Gene Expression in a Single Cell
-
Elowitz MB, Levine AJ, Siggia ED, Swain PS. Stochastic Gene Expression in a Single Cell. Science. 2002; 297(5584):1183-86.
-
(2002)
Science
, vol.297
, Issue.5584
, pp. 1183-1186
-
-
Elowitz, M.B.1
Levine, A.J.2
Siggia, E.D.3
Swain, P.S.4
-
48
-
-
25444489027
-
Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments
-
Kussell E, Leibler S. Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments. Science. 2005; 309(5743):2075-2078.
-
(2005)
Science
, vol.309
, Issue.5743
, pp. 2075-2078
-
-
Kussell, E.1
Leibler, S.2
-
49
-
-
4644343922
-
Bacterial Persistence as a Phenotypic Switch
-
Balaban NQ, Merrin J, Chait R, Kowalik L, Leibler S. Bacterial Persistence as a Phenotypic Switch. Science. 2004; 305(5690):1622-5.
-
(2004)
Science
, vol.305
, Issue.5690
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
50
-
-
33645293152
-
An excitable gene regulatory circuit induces transient cellular differentiation
-
Süel GM, Garcia-Ojalvo J, Liberman LM, Elowitz MB. An excitable gene regulatory circuit induces transient cellular differentiation. Nature. 2006; 440(7083):545-50.
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 545-550
-
-
Süel, G.M.1
Garcia-Ojalvo, J.2
Liberman, L.M.3
Elowitz, M.B.4
-
51
-
-
78649838304
-
Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene
-
Zong C, So Lh, Sepulveda LA, Skinner SO, Golding I. Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene. Mol Syst Biol. 2010; 6:440.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 440
-
-
Zong, C.1
So, L.2
Sepulveda, L.A.3
Skinner, S.O.4
Golding, I.5
-
52
-
-
84928754032
-
MicroRNA control of protein expression noise
-
Schmiedel JM, Klemm SL, Zheng Y, Sahay A, Blüthgen N, Marks DS, et al. MicroRNA control of protein expression noise. Science. 2015; 348(6230):128-132.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 128-132
-
-
Schmiedel, J.M.1
Klemm, S.L.2
Zheng, Y.3
Sahay, A.4
Blüthgen, N.5
Marks, D.S.6
-
53
-
-
84877080561
-
Genotype to Phenotype Mapping and the Fitness Landscape of the E. coli lac Promoter
-
Otwinowski J, Nemenman I. Genotype to Phenotype Mapping and the Fitness Landscape of the E. coli lac Promoter. PLoS ONE. 2013; 8(5):e61570.
-
(2013)
PLoS ONE
, vol.8
, Issue.5
, pp. e61570
-
-
Otwinowski, J.1
Nemenman, I.2
-
54
-
-
85026972246
-
Learning Quantitative Sequence-Function Relationships from Massively Parallel Experiments.
-
Atwal GS, Kinney JB. Learning Quantitative Sequence-Function Relationships from Massively Parallel Experiments. J Stat Phys. 2015:1-41.
-
(2015)
J Stat Phys.
, pp. 1-41
-
-
Atwal, G.S.1
Kinney, J.B.2
-
55
-
-
33846351302
-
Precise physical models of protein-DNA interaction from high-throughput data
-
Kinney JB, Tkačik G, Callan CG. Precise physical models of protein-DNA interaction from high-throughput data. Proc Natl Acad Sci. 2007; 104(2):501-6.
-
(2007)
Proc Natl Acad Sci
, vol.104
, Issue.2
, pp. 501-506
-
-
Kinney, J.B.1
Tkačik, G.2
Callan, C.G.3
-
57
-
-
84896855185
-
Parametric Inference in the Large Data Limit Using Maximally Informative Models
-
Kinney JB, Atwal GS. Parametric Inference in the Large Data Limit Using Maximally Informative Models. Neural Comput. 2014; 26(4):637-53.
-
(2014)
Neural Comput
, vol.26
, Issue.4
, pp. 637-653
-
-
Kinney, J.B.1
Atwal, G.S.2
-
58
-
-
84901847160
-
Inferring fitness landscapes by regression produces biased estimates of epistasis
-
Otwinowski J, Plotkin JB. Inferring fitness landscapes by regression produces biased estimates of epistasis. Proc Natl Acad Sci. 2014; 111(22):E2301-E2309.
-
(2014)
Proc Natl Acad Sci
, vol.111
, Issue.22
, pp. E2301-E2309
-
-
Otwinowski, J.1
Plotkin, J.B.2
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