Role of structural dynamics at the receptor G protein interface for signal transduction

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Rose, Alexander S ^a   Zachariae, Ulrich ^c,d   Grubmãller, Helmut ^c   Hofmann, Klaus Peter ^a,b   Scheerer, Patrick ^a   Hildebrand, Peter W ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; WATER; BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANOSINE DIPHOSPHATE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN BINDING;

ALPHA HELIX; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION;

GUANOSINE DIPHOSPHATE; HETEROTRIMERIC GTP-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84960077614     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0143399     Document Type: Article

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