-
1
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
20935630, ..;:–.
-
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature Genetics. 2010;42:937–948. doi: 10.1038/ng.68620935630
-
(2010)
Nature Genetics
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
Jackson, A.U.6
-
2
-
-
77951711343
-
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
-
20418890, .;:–.
-
Tobacco-and-Genetics-ConsortiumGenome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature Genetics. 2010;42:441–447. doi: 10.1038/ng.57120418890
-
(2010)
Nature Genetics
, vol.42
, pp. 441-447
-
-
-
3
-
-
84931411520
-
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
-
26039521, ..;:–.
-
Cannon CP, Blazing MA, Giugliano RP, McCagg A, White JA, Theroux P, et al. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. New England Journal of Medicine. 2015;372:2387–2397. doi: 10.1056/NEJMoa141048926039521
-
(2015)
New England Journal of Medicine
, vol.372
, pp. 2387-2397
-
-
Cannon, C.P.1
Blazing, M.A.2
Giugliano, R.P.3
McCagg, A.4
White, J.A.5
Theroux, P.6
-
4
-
-
84928026823
-
Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 x 2 factorial mendelian randomization study
-
25770315, .;:–.
-
Ference BA, Majeed F, Penumetcha R, Flack JM, Brook RD, Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 x 2 factorial mendelian randomization study. Journal of the American College of Cardiology. 2015;65:1552–1561. doi: 10.1016/j.jacc.2015.02.02025770315
-
(2015)
Journal of the American College of Cardiology
, vol.65
, pp. 1552-1561
-
-
Ference, B.A.1
Majeed, F.2
Penumetcha, R.3
Flack, J.M.4
Brook, R.D.5
-
5
-
-
84931375227
-
Proof That Lower Is Better—LDL Cholesterol and IMPROVE-IT
-
26039520, .;:–.
-
Jarcho JA, Keaney JF, JrProof That Lower Is Better—LDL Cholesterol and IMPROVE-IT. New England Journal of Medicine. 2015;372:2448–2450. doi: 10.1056/NEJMe150704126039520
-
(2015)
New England Journal of Medicine
, vol.372
, pp. 2448-2450
-
-
Jarcho, J.A.1
Keaney, J.F.2
-
6
-
-
0037322022
-
'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?
-
12689998, .;:–.
-
Davey Smith G, Ebrahim S, 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?International Journal of Epidemiology. 2003;32:1–22. 12689998
-
(2003)
International Journal of Epidemiology
, vol.32
, pp. 1-22
-
-
Davey Smith, G.1
Ebrahim, S.2
-
7
-
-
18444405551
-
What can Mendelian randomisation tell us about modifiable behavioural and environmental exposures?
-
15879400, .;:–.
-
Davey Smith G, Ebrahim S, What can Mendelian randomisation tell us about modifiable behavioural and environmental exposures?BMJ. 2005;330:1076–1079. 15879400
-
(2005)
BMJ
, vol.330
, pp. 1076-1079
-
-
Davey Smith, G.1
Ebrahim, S.2
-
8
-
-
38049023073
-
Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology
-
18076282, .;:.
-
Davey Smith G, Lawlor DA, Harbord R, Timpson N, Day I, Ebrahim S, Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PloS Med. 2007;4:e352. 18076282
-
(2007)
PloS Med
, vol.4
, pp. e352
-
-
Davey Smith, G.1
Lawlor, D.A.2
Harbord, R.3
Timpson, N.4
Day, I.5
Ebrahim, S.6
-
9
-
-
79952624880
-
Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health
-
21437028, .;:–.
-
Davey Smith G, Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health. Genes and Nutrition. 2011;6:27–43. doi: 10.1007/s12263-010-0181-y21437028
-
(2011)
Genes and Nutrition
, vol.6
, pp. 27-43
-
-
Davey Smith, G.1
-
10
-
-
77952717253
-
Illustrating bias due to conditioning on a collider
-
19926667, ..;:–.
-
Cole SR, Platt RW, Schisterman EF, Chu H, Westreich D, Richardson D, et al. Illustrating bias due to conditioning on a collider. International Journal of Epidemiology. 2010;39:417–420. doi: 10.1093/ije/dyp33419926667
-
(2010)
International Journal of Epidemiology
, vol.39
, pp. 417-420
-
-
Cole, S.R.1
Platt, R.W.2
Schisterman, E.F.3
Chu, H.4
Westreich, D.5
Richardson, D.6
-
11
-
-
41649103052
-
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
-
18385739, ..;:–.
-
Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, Magnusson KP, et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature. 2008;452:638–642. doi: 10.1038/nature0684618385739
-
(2008)
Nature
, vol.452
, pp. 638-642
-
-
Thorgeirsson, T.E.1
Geller, F.2
Sulem, P.3
Rafnar, T.4
Wiste, A.5
Magnusson, K.P.6
-
12
-
-
82455172054
-
Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis
-
.;:–.
-
Ware JJ, van den Bree MB, Munafo MR, Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis. Nicotine & Tobacco Research. 2011;13:1167–1175.
-
(2011)
Nicotine & Tobacco Research
, vol.13
, pp. 1167-1175
-
-
Ware, J.J.1
van den Bree, M.B.2
Munafo, M.R.3
-
13
-
-
84861325364
-
Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure
-
22534784, ..;:–.
-
Munafo MR, Timofeeva MN, Morris RW, Prieto-Merino D, Sattar N, Brennan P, et al. Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. Journal of the National Cancer Institute. 2012;104:740–748. doi: 10.1093/jnci/djs19122534784
-
(2012)
Journal of the National Cancer Institute
, vol.104
, pp. 740-748
-
-
Munafo, M.R.1
Timofeeva, M.N.2
Morris, R.W.3
Prieto-Merino, D.4
Sattar, N.5
Brennan, P.6
-
14
-
-
42649091460
-
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
-
18385676, ..;:–.
-
Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nature Genetics. 2008;40:616–622. doi: 10.1038/ng.10918385676
-
(2008)
Nature Genetics
, vol.40
, pp. 616-622
-
-
Amos, C.I.1
Wu, X.2
Broderick, P.3
Gorlov, I.P.4
Gu, J.5
Eisen, T.6
-
15
-
-
63449101907
-
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci
-
19300482, ..;:.
-
Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, et al. A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet. 2009;5:e1000421. doi: 10.1371/journal.pgen.100042119300482
-
(2009)
PLoS Genet
, vol.5
, pp. e1000421
-
-
Pillai, S.G.1
Ge, D.2
Zhu, G.3
Kong, X.4
Shianna, K.V.5
Need, A.C.6
-
16
-
-
79955725571
-
Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk
-
21559498, .;:.
-
Wang Y, Broderick P, Matakidou A, Eisen T, Houlston RS, Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk. PLoS ONE. 2011;6:e19085. doi: 10.1371/journal.pone.001908521559498
-
(2011)
PLoS ONE
, vol.6
, pp. e19085
-
-
Wang, Y.1
Broderick, P.2
Matakidou, A.3
Eisen, T.4
Houlston, R.S.5
-
17
-
-
84868156549
-
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls
-
22899653, ..;:–.
-
Timofeeva MN, Hung RJ, Rafnar T, Christiani DC, Field JK, Bickeboller H, et al. Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Human Molecular Genetics. 2012;21:4980–4395. doi: 10.1093/hmg/dds33422899653
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 4395-4980
-
-
Timofeeva, M.N.1
Hung, R.J.2
Rafnar, T.3
Christiani, D.C.4
Field, J.K.5
Bickeboller, H.6
-
18
-
-
84885935952
-
Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway
-
23443019, .;:–.
-
Gabrielsen ME, Romundstad P, Langhammer A, Krokan HE, Skorpen F, Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway. European Journal of Human Genetics. 2013;21:1293–1299. doi: 10.1038/ejhg.2013.2623443019
-
(2013)
European Journal of Human Genetics
, vol.21
, pp. 1293-1299
-
-
Gabrielsen, M.E.1
Romundstad, P.2
Langhammer, A.3
Krokan, H.E.4
Skorpen, F.5
-
19
-
-
33747041432
-
Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians
-
16822169, .;:–.
-
Luczak SE, Glatt SJ, Wall TL, Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians. Psychological Bulletin. 2006;132:607–621. 16822169
-
(2006)
Psychological Bulletin
, vol.132
, pp. 607-621
-
-
Luczak, S.E.1
Glatt, S.J.2
Wall, T.L.3
-
20
-
-
80053907554
-
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
-
21909115, ..;:–.
-
International Consortium for Blood Pressure Genome-Wide AssociationS Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478:103–109. doi: 10.1038/nature1040521909115
-
(2011)
Nature
, vol.478
, pp. 103-109
-
-
S1
Ehret, G.B.2
Munroe, P.B.3
Rice, K.M.4
Bochud, M.5
Johnson, A.D.6
-
21
-
-
79957585975
-
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
-
21572416, ..;:–.
-
Kato N, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, et al. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nature Genetics. 2011;43:531–538. doi: 10.1038/ng.83421572416
-
(2011)
Nature Genetics
, vol.43
, pp. 531-538
-
-
Kato, N.1
Takeuchi, F.2
Tabara, Y.3
Kelly, T.N.4
Go, M.J.5
Sim, X.6
-
22
-
-
84922421928
-
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
-
25249183, ..;:–.
-
Lu X, Wang L, Lin X, Huang J, Charles Gu C, He M, et al. Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. Human Molecular Genetics. 2015;24:865–874. doi: 10.1093/hmg/ddu47825249183
-
(2015)
Human Molecular Genetics
, vol.24
, pp. 865-874
-
-
Lu, X.1
Wang, L.2
Lin, X.3
Huang, J.4
Charles Gu, C.5
He, M.6
-
23
-
-
41549104622
-
Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach
-
18318597, .;:.
-
Chen L, Davey Smith G, Harbord RM, Lewis SJ, Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med. 2008;5:e52. doi: 10.1371/journal.pmed.005005218318597
-
(2008)
PLoS Med
, vol.5
, pp. e52
-
-
Chen, L.1
Davey Smith, G.2
Harbord, R.M.3
Lewis, S.J.4
-
24
-
-
84866919001
-
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
-
22960999, ..;:–.
-
Wu C, Kraft P, Zhai K, Chang J, Wang Z, Li Y, et al. Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nature Genetics. 2012;44:1090–1097. doi: 10.1038/ng.241122960999
-
(2012)
Nature Genetics
, vol.44
, pp. 1090-1097
-
-
Wu, C.1
Kraft, P.2
Zhai, K.3
Chang, J.4
Wang, Z.5
Li, Y.6
-
25
-
-
23844550544
-
Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach
-
.;:–.
-
Lewis SJ, Davey Smith G, Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach. Cancer Epidemiology, Biomarkers & Prevention. 2005;14:1967–1971.
-
(2005)
Cancer Epidemiology, Biomarkers & Prevention
, vol.14
, pp. 1967-1971
-
-
Lewis, S.J.1
Davey Smith, G.2
-
26
-
-
79955579254
-
Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption
-
21490707, ..;:.
-
Cornelis MC, Monda KL, Yu K, Paynter N, Azzato EM, Bennett SN, et al. Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. PLoS Genetics. 2011;7:e1002033. doi: 10.1371/journal.pgen.100203321490707
-
(2011)
PLoS Genetics
, vol.7
, pp. e1002033
-
-
Cornelis, M.C.1
Monda, K.L.2
Yu, K.3
Paynter, N.4
Azzato, E.M.5
Bennett, S.N.6
-
27
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
25056061, .;:–.
-
Schizophrenia-Working-Group-of-the-Psychiatric-Genomics-ConsortiumBiological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511:421–427. doi: 10.1038/nature1359525056061
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
-
28
-
-
84938292772
-
Does tobacco use cause psychosis? Systematic review and meta-analysis
-
26249303, .;:–.
-
Gurillo P, Jauhar S, Murray R, MacCabe JH, Does tobacco use cause psychosis? Systematic review and meta-analysis. Lancet Psychiatry. 2015;2:718–725. doi: 10.1016/S2215-0366(15)00152-226249303
-
(2015)
Lancet Psychiatry
, vol.2
, pp. 718-725
-
-
Gurillo, P.1
Jauhar, S.2
Murray, R.3
MacCabe, J.H.4
-
29
-
-
84938294188
-
Smoking and schizophrenia in population cohorts of Swedish women and men: A prospective co-relative control study
-
.;():–.
-
Kendler KS, Lonn SL, Sundquist J, Sundquist K, Smoking and schizophrenia in population cohorts of Swedish women and men: A prospective co-relative control study. American Journal of Psychiatry. 2015; 117(11):1092–1100.
-
(2015)
American Journal of Psychiatry
, vol.117
, Issue.11
, pp. 1092-1100
-
-
Kendler, K.S.1
Lonn, S.L.2
Sundquist, J.3
Sundquist, K.4
-
30
-
-
84970967357
-
Age at first tobacco use and risk of subsequent psychosis-related outcomes: A birth cohort study
-
.. E-pub ahead of print.
-
McGrath J, Alati R, Clavarino A, Williams G, Bor W, Najman J, et al. Age at first tobacco use and risk of subsequent psychosis-related outcomes: A birth cohort study. Australian and New Zealand Journal of Psychiatry. 2015. E-pub ahead of print. doi: 10.1177/0004867415587341
-
(2015)
Australian and New Zealand Journal of Psychiatry
-
-
McGrath, J.1
Alati, R.2
Clavarino, A.3
Williams, G.4
Bor, W.5
Najman, J.6
-
31
-
-
84936755192
-
Tobacco smoking is causally associated with antipsychotic medication use and schizophrenia, but not with antidepressant medication use or depression
-
26054357, .;():–.
-
Wium-Andersen MK, Orsted DD, Nordestgaard BG, Tobacco smoking is causally associated with antipsychotic medication use and schizophrenia, but not with antidepressant medication use or depression. International journal of Epidemiology. 2015; 44(2):566–577. doi: 10.1093/ije/dyv09026054357
-
(2015)
International journal of Epidemiology
, vol.44
, Issue.2
, pp. 566-577
-
-
Wium-Andersen, M.K.1
Orsted, D.D.2
Nordestgaard, B.G.3
-
32
-
-
84908504595
-
Genetic predisposition to schizophrenia associated with increased use of cannabis
-
24957864, ..;:–.
-
Power RA, Verweij KJ, Zuhair M, Montgomery GW, Henders AK, Heath AC, et al. Genetic predisposition to schizophrenia associated with increased use of cannabis. Molecular Psychiatry. 2014;19:1201–1204. doi: 10.1038/mp.2014.5124957864
-
(2014)
Molecular Psychiatry
, vol.19
, pp. 1201-1204
-
-
Power, R.A.1
Verweij, K.J.2
Zuhair, M.3
Montgomery, G.W.4
Henders, A.K.5
Heath, A.C.6
-
33
-
-
84906838227
-
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
-
25064373, .;:–.
-
Davey Smith G, Hemani G, Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Human Molecular Genetics. 2014;23:R89–98. doi: 10.1093/hmg/ddu32825064373
-
(2014)
Human Molecular Genetics
, vol.23
, pp. R89-98
-
-
Davey Smith, G.1
Hemani, G.2
-
34
-
-
84953791273
-
Causal inference in Developmental Origins of Health and Disease (DOHaD) research
-
26442667, .;:–.
-
Gage SH, Munafo MR, Davey Smith G, Causal inference in Developmental Origins of Health and Disease (DOHaD) research. Annual Review of Psychology. 2015;67:567–85. doi: 10.1146/annurev-psych-122414-03335226442667
-
(2015)
Annual Review of Psychology
, vol.67
, pp. 567-585
-
-
Gage, S.H.1
Munafo, M.R.2
Davey Smith, G.3
-
35
-
-
85000692305
-
An atlas of genetic correlations across human diseases and traits
-
..:();–.
-
Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Consortium R, et al. An atlas of genetic correlations across human diseases and traits. bioRxiv. 2015:47(11);1236–41.
-
(2015)
bioRxiv
, vol.47
, Issue.11
, pp. 1236-1241
-
-
Bulik-Sullivan, B.1
Finucane, H.K.2
Anttila, V.3
Gusev, A.4
Day, F.R.5
Consortium, R.6
-
36
-
-
84963649396
-
Detection and interpretation of shared genetic influences on 40 human traits
-
Pickrell J, Berisa T, Segurel L, Tung JY, Hinds D, Detection and interpretation of shared genetic influences on 40 human traits. bioRxiv. 2015. doi: 10.1101/019885http://biorxiv.org/content/early/2015/05/27/019885
-
(2015)
bioRxiv
-
-
Pickrell, J.1
Berisa, T.2
Segurel, L.3
Tung, J.Y.4
Hinds, D.5
-
37
-
-
84936755918
-
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
-
26050253, .;:–.
-
Bowden J, Davey Smith G, Burgess S, Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. International journal of epidemiology. 2015;44:512–525. doi: 10.1093/ije/dyv08026050253
-
(2015)
International journal of epidemiology
, vol.44
, pp. 512-525
-
-
Bowden, J.1
Davey Smith, G.2
Burgess, S.3
-
38
-
-
84946954072
-
Instrumental variables estimation with some invalid instruments and its application to Mendelian randomization
-
.. E-pub ahead of print.
-
Kang H, Zhang A, Cai TT, Small DS, Instrumental variables estimation with some invalid instruments and its application to Mendelian randomization. Journal of the American Statistical Association. 2015. E-pub ahead of print. http://arxiv.org/abs/1401.5755
-
(2015)
Journal of the American Statistical Association
-
-
Kang, H.1
Zhang, A.2
Cai, T.T.3
Small, D.S.4
-
39
-
-
33846510020
-
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
-
17135278, ..;:–.
-
Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA, et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Human Molecular Genetics. 2007;16:36–49. 17135278
-
(2007)
Human Molecular Genetics
, vol.16
, pp. 36-49
-
-
Saccone, S.F.1
Hinrichs, A.L.2
Saccone, N.L.3
Chase, G.A.4
Konvicka, K.5
Madden, P.A.6
-
40
-
-
51349156208
-
Variants in nicotinic receptors and risk for nicotine dependence
-
18519524, ..;:–.
-
Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X, et al. Variants in nicotinic receptors and risk for nicotine dependence. American Journal of Psychiatry. 2008;165:1163–1171. doi: 10.1176/appi.ajp.2008.0711171118519524
-
(2008)
American Journal of Psychiatry
, vol.165
, pp. 1163-1171
-
-
Bierut, L.J.1
Stitzel, J.A.2
Wang, J.C.3
Hinrichs, A.L.4
Grucza, R.A.5
Xuei, X.6
-
41
-
-
79953246461
-
Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake
-
21278726, .;:–.
-
Fowler CD, Lu Q, Johnson PM, Marks MJ, Kenny PJ, Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake. Nature. 2011;471:597–601. doi: 10.1038/nature0979721278726
-
(2011)
Nature
, vol.471
, pp. 597-601
-
-
Fowler, C.D.1
Lu, Q.2
Johnson, P.M.3
Marks, M.J.4
Kenny, P.J.5
-
42
-
-
77951748276
-
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
-
20418888, ..;:–.
-
Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nature Genetics. 2010;42:448–453. doi: 10.1038/ng.57320418888
-
(2010)
Nature Genetics
, vol.42
, pp. 448-453
-
-
Thorgeirsson, T.E.1
Gudbjartsson, D.F.2
Surakka, I.3
Vink, J.M.4
Amin, N.5
Geller, F.6
-
43
-
-
84861308971
-
Genome-wide meta-analyses of smoking behaviors in African Americans
-
..;:.
-
David SP, Hamidovic A, Chen GK, Bergen AW, Wessel J, Kasberger JL, et al. Genome-wide meta-analyses of smoking behaviors in African Americans. Translational Psychiatry. 2012;2:e119.
-
(2012)
Translational Psychiatry
, vol.2
, pp. e119
-
-
David, S.P.1
Hamidovic, A.2
Chen, G.K.3
Bergen, A.W.4
Wessel, J.5
Kasberger, J.L.6
-
44
-
-
77951751034
-
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
-
20418889, ..;:–.
-
Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature Genetics. 2010;42:436–440. doi: 10.1038/ng.57220418889
-
(2010)
Nature Genetics
, vol.42
, pp. 436-440
-
-
Liu, J.Z.1
Tozzi, F.2
Waterworth, D.M.3
Pillai, S.G.4
Muglia, P.5
Middleton, L.6
-
45
-
-
79960703027
-
Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study
-
21646606, .;:–.
-
Kaur-Knudsen D, Bojesen SE, Tybjaerg-Hansen A, Nordestgaard BG, Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study. Journal of Clinical Oncology. 2011;29:2875–2882. doi: 10.1200/JCO.2010.32.987021646606
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 2875-2882
-
-
Kaur-Knudsen, D.1
Bojesen, S.E.2
Tybjaerg-Hansen, A.3
Nordestgaard, B.G.4
-
46
-
-
77649087948
-
The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema
-
20007924, ..;:–.
-
Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, Cuppens H, et al. The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema. American Journal of Respiratory and Critical Care Medicine. 2010;181:486–493. doi: 10.1164/rccm.200909-1364OC20007924
-
(2010)
American Journal of Respiratory and Critical Care Medicine
, vol.181
, pp. 486-493
-
-
Lambrechts, D.1
Buysschaert, I.2
Zanen, P.3
Coolen, J.4
Lays, N.5
Cuppens, H.6
-
47
-
-
77951766653
-
Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals
-
19776245, ..;:–.
-
Lips EH, Gaborieau V, McKay JD, Chabrier A, Hung RJ, Boffetta P, et al. Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. International Journal of Epidemiology. 2010;39:563–577. doi: 10.1093/ije/dyp28819776245
-
(2010)
International Journal of Epidemiology
, vol.39
, pp. 563-577
-
-
Lips, E.H.1
Gaborieau, V.2
McKay, J.D.3
Chabrier, A.4
Hung, R.J.5
Boffetta, P.6
-
49
-
-
56449101208
-
Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine
-
19010884, ..;:–.
-
Le Marchand L, Derby KS, Murphy SE, Hecht SS, Hatsukami D, Carmella SG, et al. Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine. Cancer Research. 2008;68:9137–9140. doi: 10.1158/0008-5472.CAN-08-227119010884
-
(2008)
Cancer Research
, vol.68
, pp. 9137-9140
-
-
Le Marchand, L.1
Derby, K.S.2
Murphy, S.E.3
Hecht, S.S.4
Hatsukami, D.5
Carmella, S.G.6
-
50
-
-
70349573295
-
Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15
-
19628476, ..;:–.
-
Keskitalo K, Broms U, Heliovaara M, Ripatti S, Surakka I, Perola M, et al. Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. Human Molecular Genetics. 2009;18:4007–4012. doi: 10.1093/hmg/ddp32219628476
-
(2009)
Human Molecular Genetics
, vol.18
, pp. 4007-4012
-
-
Keskitalo, K.1
Broms, U.2
Heliovaara, M.3
Ripatti, S.4
Surakka, I.5
Perola, M.6
-
52
-
-
2342647955
-
The relation of adaptability to adaptation
-
.;:–.
-
Gause GF, The relation of adaptability to adaptation. Quarterly Review of Biology. 1942;17:99–114.
-
(1942)
Quarterly Review of Biology
, vol.17
, pp. 99-114
-
-
Gause, G.F.1
-
53
-
-
0023767429
-
Concentration-affinity equivalence in gene regulation: convergence of genetic and environmental effects
-
.;:–.
-
Zuckerkandl E, Villet R, Concentration-affinity equivalence in gene regulation: convergence of genetic and environmental effects. Proceedings of the National Academy of Sciences USA. 1988;85:4784–4788.
-
(1988)
Proceedings of the National Academy of Sciences USA
, vol.85
, pp. 4784-4788
-
-
Zuckerkandl, E.1
Villet, R.2
-
54
-
-
84856718639
-
Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions
-
22247045, .;:–.
-
Glymour MM, Tchetgen Tchetgen EJ, Robins JM, Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions. American Journal of Epidemiology. 2012;175:332–339. doi: 10.1093/aje/kwr32322247045
-
(2012)
American Journal of Epidemiology
, vol.175
, pp. 332-339
-
-
Glymour, M.M.1
Tchetgen Tchetgen, E.J.2
Robins, J.M.3
-
55
-
-
84913588391
-
Commentary: Does mortality from smoking have implications for future Mendelian randomization studies?
-
25125581, .;:–.
-
Taylor AE, Munafo MR, CARTA ConsortiumCommentary: Does mortality from smoking have implications for future Mendelian randomization studies?International Journal of Epidemiology. 2014;43:1483–1486. doi: 10.1093/ije/dyu15125125581
-
(2014)
International Journal of Epidemiology
, vol.43
, pp. 1483-1486
-
-
Taylor, A.E.1
Munafo, M.R.2
-
56
-
-
84889584152
-
Gene x environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution
-
24135711, .;:–.
-
Keller MC, Gene x environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution. Biological Psychiatry. 2014;75:18–24. doi: 10.1016/j.biopsych.2013.09.00624135711
-
(2014)
Biological Psychiatry
, vol.75
, pp. 18-24
-
-
Keller, M.C.1
-
57
-
-
44349179705
-
Multiple ADH genes are associated with upper aerodigestive cancers
-
18500343, ..;:–.
-
Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, et al. Multiple ADH genes are associated with upper aerodigestive cancers. Nature Genetics. 2008;40:707–709. doi: 10.1038/ng.15118500343
-
(2008)
Nature Genetics
, vol.40
, pp. 707-709
-
-
Hashibe, M.1
McKay, J.D.2
Curado, M.P.3
Oliveira, J.C.4
Koifman, S.5
Koifman, R.6
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