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Volumn 13, Issue 12, 2011, Pages 1167-1175

Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

CHRNA3 PROTEIN; CHRNA5 PROTEIN; CHRNB4 PROTEIN; UNCLASSIFIED DRUG;

EID: 82455172054     PISSN: 14622203     EISSN: 1469994X     Source Type: Journal    
DOI: 10.1093/ntr/ntr118     Document Type: Article
Times cited : (99)

References (58)
  • 1
    • 42649091460 scopus 로고    scopus 로고
    • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
    • doi:10.1038/ng.109
    • Amos, C. I., Wu, X., Broderick, P., Gorlov, I. P., Gu, J., Eisen, T., et al. (2008). Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nature Genetics, 40, 616-622. doi:10.1038/ng.109.
    • (2008) Nature Genetics , vol.40 , pp. 616-622
    • Amos, C.I.1    Wu, X.2    Broderick, P.3    Gorlov, I.P.4    Gu, J.5    Eisen, T.6
  • 2
    • 67650239435 scopus 로고    scopus 로고
    • Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes
    • doi:10.1093/ntr/ntp064
    • Baker, T. B., Weiss, R. B., Bolt, D., von Niederhausern, A., Fiore, M. C., Dunn, D. M., et al. (2009). Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. Nicotine & Tobacco Research, 11, 785-796. doi:10.1093/ntr/ntp064.
    • (2009) Nicotine & Tobacco Research , vol.11 , pp. 785-796
    • Baker, T.B.1    Weiss, R.B.2    Bolt, D.3    von Niederhausern, A.4    Fiore, M.C.5    Dunn, D.M.6
  • 3
    • 40849097777 scopus 로고    scopus 로고
    • Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking
    • doi:10.1038/sj.mp.4002154
    • Berrettini, W., Yuan, X., Tozzi, F., Song, K., Francks, C., Chilcoat, H., et al. (2008). Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Molecular Psychiatry, 13, 368-373. doi:10.1038/sj.mp.4002154.
    • (2008) Molecular Psychiatry , vol.13 , pp. 368-373
    • Berrettini, W.1    Yuan, X.2    Tozzi, F.3    Song, K.4    Francks, C.5    Chilcoat, H.6
  • 4
    • 73049084248 scopus 로고    scopus 로고
    • Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25
    • doi:10.1016/j.tips.2009.10.004
    • Bierut, L. J. (2010). Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. Trends in Pharmacological Sciences, 31, 46-51. doi:10.1016/j.tips.2009.10.004.
    • (2010) Trends in Pharmacological Sciences , vol.31 , pp. 46-51
    • Bierut, L.J.1
  • 5
    • 51349156208 scopus 로고    scopus 로고
    • Variants in nicotinic receptors and risk for nicotine dependence
    • doi:10.1176/appi.ajp.2008.07111711
    • Bierut, L. J., Stitzel, J. A., Wang, J. C., Hinrichs, A. L., Grucza, R. A., Xuei, X., et al. (2008). Variants in nicotinic receptors and risk for nicotine dependence. American Journal of Psychiatry, 165, 1163-1171. doi:10.1176/appi.ajp.2008.07111711.
    • (2008) American Journal of Psychiatry , vol.165 , pp. 1163-1171
    • Bierut, L.J.1    Stitzel, J.A.2    Wang, J.C.3    Hinrichs, A.L.4    Grucza, R.A.5    Xuei, X.6
  • 6
    • 62749189901 scopus 로고    scopus 로고
    • Smoking cessation and variations in nicotinic acetylcholine receptor subunits α-5, α-3, and β-4 genes
    • doi:10.1016/j.biopsych.2008.10.004
    • Breitling, L. P., Dahmen, N., Mittelstraß, K., Illig, T., Rujescu, D., Raum, E., et al. (2009). Smoking cessation and variations in nicotinic acetylcholine receptor subunits α-5, α-3, and β-4 genes. Biological Psychiatry, 65, 691-695. doi:10.1016/j.biopsych.2008.10.004.
    • (2009) Biological Psychiatry , vol.65 , pp. 691-695
    • Breitling, L.P.1    Dahmen, N.2    Mittelstraß, K.3    Illig, T.4    Rujescu, D.5    Raum, E.6
  • 7
    • 69249133245 scopus 로고    scopus 로고
    • Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study
    • doi:10.1158/0008-5472.CAN-09-0680
    • Broderick, P., Wang, Y., Vijayakrishnan, J., Matakidou, A., Spitz, M. R., Eisen, T., et al. (2009). Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study. Cancer Research, 69, 6633-6641. doi:10.1158/0008-5472.CAN-09-0680.
    • (2009) Cancer Research , vol.69 , pp. 6633-6641
    • Broderick, P.1    Wang, Y.2    Vijayakrishnan, J.3    Matakidou, A.4    Spitz, M.R.5    Eisen, T.6
  • 8
    • 84864279400 scopus 로고    scopus 로고
    • Genome-wide and candidate gene association study of cigarette smoking behaviors
    • Retrieved from
    • Caporaso, N., Gu, F., Chatterjee, N., Sheng-Chih, J., Yu, K., Yeager, M., et al. (2009). Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One, 4, Retrieved from http://plosone.org/.
    • (2009) PLoS One , pp. 4
    • Caporaso, N.1    Gu, F.2    Chatterjee, N.3    Sheng-Chih, J.4    Yu, K.5    Yeager, M.6
  • 9
    • 69949149819 scopus 로고    scopus 로고
    • Interplay of genetic risk factors and parent monitoring in risk for nicotine dependence
    • doi:10.1111/j.1360-0443.2009.02697.x
    • Chen, L. S., Johnson, E. O., Breslau, N., Hatsukami, D., Saccone, N. L., Grucza, R. A., et al. (2009). Interplay of genetic risk factors and parent monitoring in risk for nicotine dependence. Addiction, 104, 1731-1740. doi:10.1111/j.1360-0443.2009.02697.x.
    • (2009) Addiction , vol.104 , pp. 1731-1740
    • Chen, L.S.1    Johnson, E.O.2    Breslau, N.3    Hatsukami, D.4    Saccone, N.L.5    Grucza, R.A.6
  • 11
    • 50849143769 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor β2 subunit gene implicated in a systems-based candidate gene study of smoking cessation
    • doi:10.1093/hmg/ddn181
    • Conti, D. V., Lee, W., Li, D., Liu, J., Van den Berg, D., Thomas, P. D., et al. (2008). Nicotinic acetylcholine receptor β2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Human Molecular Genetics, 17, 2834-2848. doi:10.1093/hmg/ddn181.
    • (2008) Human Molecular Genetics , vol.17 , pp. 2834-2848
    • Conti, D.V.1    Lee, W.2    Li, D.3    Liu, J.4    Van den Berg, D.5    Thomas, P.D.6
  • 12
    • 0033934949 scopus 로고    scopus 로고
    • Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis
    • doi:10.1111/j.0006-341X.2000.00455.x
    • Duval, S., & Tweedie, R. (2000). Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 56, 455-463. doi:10.1111/j.0006-341X.2000.00455.x.
    • (2000) Biometrics , vol.56 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 13
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Retrieved from
    • Egger, M., Davey Smith, G., Schneider, M., & Minder, C. (1997). Bias in meta-analysis detected by a simple, graphical test. British Medical Journal, 315, 629-634. Retrieved from http://www.bmj.com/.
    • (1997) British Medical Journal , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 14
    • 67349118804 scopus 로고    scopus 로고
    • Association of genes coding for the α-4, α-5, β-2 and β-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence
    • doi:10.1016/j.addbeh.2009.05.010
    • Etter, J. F., Hoda, J. C., Perroud, N., Munafo, M., Buresi, C., Duret, C., et al. (2009). Association of genes coding for the α-4, α-5, β-2 and β-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence. Addictive Behaviors, 34, 772-775. doi:10.1016/j.addbeh.2009.05.010.
    • (2009) Addictive Behaviors , vol.34 , pp. 772-775
    • Etter, J.F.1    Hoda, J.C.2    Perroud, N.3    Munafo, M.4    Buresi, C.5    Duret, C.6
  • 15
    • 33846907760 scopus 로고    scopus 로고
    • Exploring the relationship between genetic and environmental influences on initiation and progression of substance use
    • doi:10.1111/j.1360-0443.2006.01694.x
    • Fowler, T., Lifford, K., Shelton, K., Rice, F., Thapar, A., Neale, M. C., et al. (2007). Exploring the relationship between genetic and environmental influences on initiation and progression of substance use. Addiction, 102, 413-422. doi:10.1111/j.1360-0443.2006.01694.x.
    • (2007) Addiction , vol.102 , pp. 413-422
    • Fowler, T.1    Lifford, K.2    Shelton, K.3    Rice, F.4    Thapar, A.5    Neale, M.C.6
  • 16
    • 67650770278 scopus 로고    scopus 로고
    • A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy
    • doi:10.1093/hmg/ddp216
    • Freathy, R. M., Ring, S. M., Shields, B., Galobardes, B., Knight, B., Weedon, M. N., et al. (2009). A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. Human Molecular Genetics, 18, 2922-2927. doi:10.1093/hmg/ddp216.
    • (2009) Human Molecular Genetics , vol.18 , pp. 2922-2927
    • Freathy, R.M.1    Ring, S.M.2    Shields, B.3    Galobardes, B.4    Knight, B.5    Weedon, M.N.6
  • 17
    • 77951711343 scopus 로고    scopus 로고
    • Genome-wide meta-analyses identify multiple loci associated with smoking behavior
    • doi:10.1038/ng.571
    • Furberg, H., Kim, Y., Dackor, J., Boerwinkle, E., Franceschini, N., Ardissino, D., et al. (2010). Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature Genetics, 42, 441-447. doi:10.1038/ng.571.
    • (2010) Nature Genetics , vol.42 , pp. 441-447
    • Furberg, H.1    Kim, Y.2    Dackor, J.3    Boerwinkle, E.4    Franceschini, N.5    Ardissino, D.6
  • 18
    • 33747422892 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptors: Native subtypes and their relevance
    • doi:10.1016/j.tips.2006.07.004
    • Gotti, C., Zoli, M., & Clementi, F. (2006). Brain nicotinic acetylcholine receptors: Native subtypes and their relevance. Trends in Pharmacological Sciences, 27, 482-491. doi:10.1016/j.tips.2006.07.004.
    • (2006) Trends in Pharmacological Sciences , vol.27 , pp. 482-491
    • Gotti, C.1    Zoli, M.2    Clementi, F.3
  • 19
    • 33644614050 scopus 로고    scopus 로고
    • Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes
    • doi:10.1038/sj.mp.4001774
    • Greenbaum, L., Kanyas, K., Karni, O., Merbl, Y., Olender, T., Horowitz, A., et al. (2006). Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes. Molecular Psychiatry, 11, 312-322. doi:10.1038/sj.mp.4001774.
    • (2006) Molecular Psychiatry , vol.11 , pp. 312-322
    • Greenbaum, L.1    Kanyas, K.2    Karni, O.3    Merbl, Y.4    Olender, T.5    Horowitz, A.6
  • 20
    • 69249129065 scopus 로고    scopus 로고
    • Role of genetic variants in the CHRNA5-CHRNA3-CHRNB4 cluster in nicotine dependence risk: Importance of gene-environment interplay
    • doi:10.1038/mp.2009.25
    • Greenbaum, L., Rigbi, A., Teltsh, O., & Lerer, B. (2009). Role of genetic variants in the CHRNA5-CHRNA3-CHRNB4 cluster in nicotine dependence risk: Importance of gene-environment interplay. Molecular Psychiatry, 14, 828-830. doi:10.1038/mp.2009.25.
    • (2009) Molecular Psychiatry , vol.14 , pp. 828-830
    • Greenbaum, L.1    Rigbi, A.2    Teltsh, O.3    Lerer, B.4
  • 21
    • 55349143211 scopus 로고    scopus 로고
    • A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence
    • doi:10.1016/j.biopsych.2008.04.018
    • Grucza, R. A., Wang, J. C., Stitzel, J. A., Hinrichs, A. L., Saccone, S. F., Saccone, N. L., et al. (2008). A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biological Psychiatry, 64, 922-929. doi:10.1016/j.biopsych.2008.04.018.
    • (2008) Biological Psychiatry , vol.64 , pp. 922-929
    • Grucza, R.A.1    Wang, J.C.2    Stitzel, J.A.3    Hinrichs, A.L.4    Saccone, S.F.5    Saccone, N.L.6
  • 22
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • doi:10.1038/nature06885
    • Hung, R. J., McKay, J. D., Gaborieau, V., Boffetta, P., Hashibe, M., Zaridze, D., et al. (2008). A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature, 452, 633-637. doi:10.1038/nature06885.
    • (2008) Nature , vol.452 , pp. 633-637
    • Hung, R.J.1    McKay, J.D.2    Gaborieau, V.3    Boffetta, P.4    Hashibe, M.5    Zaridze, D.6
  • 23
    • 0032990447 scopus 로고    scopus 로고
    • A population-based twin study in women of smoking initiation and nicotine dependence
    • doi:10.1017/S0033291798008022
    • Kendler, K. S., Neale, M. C., Sullivan, P., Corey, L. A., Gardner, C. O., & Prescott, C. A. (1999). A population-based twin study in women of smoking initiation and nicotine dependence. Psychological Medicine, 29, 299-308. doi:10.1017/S0033291798008022.
    • (1999) Psychological Medicine , vol.29 , pp. 299-308
    • Kendler, K.S.1    Neale, M.C.2    Sullivan, P.3    Corey, L.A.4    Gardner, C.O.5    Prescott, C.A.6
  • 24
    • 70349573295 scopus 로고    scopus 로고
    • Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15
    • doi:10.1093/hmg/ddp322
    • Keskitalo, K., Broms, U., Heliövaara, M., Ripatti, S., Surakka, I., Perola, M., et al. (2009). Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. Human Molecular Genetics, 18, 4007-4012. doi:10.1093/hmg/ddp322.
    • (2009) Human Molecular Genetics , vol.18 , pp. 4007-4012
    • Keskitalo, K.1    Broms, U.2    Heliövaara, M.3    Ripatti, S.4    Surakka, I.5    Perola, M.6
  • 25
    • 77649087948 scopus 로고    scopus 로고
    • The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema
    • doi:10.1164/rccm.200909-1364OC
    • Lambrechts, D., Buysschaert, I., Zanen, P., Coolen, J., Lays, N., Cuppens, H., et al. (2010). The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema. American Journal of Respiratory and Critical Care Medicine, 181, 486-493. doi:10.1164/rccm.200909-1364OC.
    • (2010) American Journal of Respiratory and Critical Care Medicine , vol.181 , pp. 486-493
    • Lambrechts, D.1    Buysschaert, I.2    Zanen, P.3    Coolen, J.4    Lays, N.5    Cuppens, H.6
  • 26
    • 72149129508 scopus 로고    scopus 로고
    • A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
    • doi:10.1016/j.ajhg.2009.09.012
    • Landi, M. T., Chatterjee, N., Yu, K., Goldin, L. R., Goldstein, A. M., Rotunno, M., et al. (2009). A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. American Journal of Human Genetics, 85, 679-691. doi:10.1016/j.ajhg.2009.09.012.
    • (2009) American Journal of Human Genetics , vol.85 , pp. 679-691
    • Landi, M.T.1    Chatterjee, N.2    Yu, K.3    Goldin, L.R.4    Goldstein, A.M.5    Rotunno, M.6
  • 27
    • 56449101208 scopus 로고    scopus 로고
    • Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine
    • doi:10.1158/0008-5472.CAN-08-2271
    • Le Marchand, L., Derby, K. S., Murphy, S. E., Hecht, S. S., Hatsukami, D., Carmella, S. G., et al. (2008). Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine. Cancer Research, 68, 9137-9140. doi:10.1158/0008-5472.CAN-08-2271.
    • (2008) Cancer Research , vol.68 , pp. 9137-9140
    • Le Marchand, L.1    Derby, K.S.2    Murphy, S.E.3    Hecht, S.S.4    Hatsukami, D.5    Carmella, S.G.6
  • 28
    • 4143061370 scopus 로고    scopus 로고
    • Defining nicotine dependence for genetic research: Evidence from Australian twins
    • doi:10.1017/S0033291703001582
    • Lessov, C. N., Martin, N. G., Statham, D. J., Todorov, A. A., Slutske, W. S., Bucholz, K. K., et al. (2004). Defining nicotine dependence for genetic research: Evidence from Australian twins. Psychological Medicine, 34, 865-879. doi:10.1017/S0033291703001582.
    • (2004) Psychological Medicine , vol.34 , pp. 865-879
    • Lessov, C.N.1    Martin, N.G.2    Statham, D.J.3    Todorov, A.A.4    Slutske, W.S.5    Bucholz, K.K.6
  • 29
    • 0037221274 scopus 로고    scopus 로고
    • A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins
    • doi:10.1046/j.1360-0443.2003.00295.x
    • Li, M. D., Cheng, R., Ma, J. Z., & Swan, G. E. (2003). A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction, 98, 23-31. doi:10.1046/j.1360-0443.2003.00295.x.
    • (2003) Addiction , vol.98 , pp. 23-31
    • Li, M.D.1    Cheng, R.2    Ma, J.Z.3    Swan, G.E.4
  • 30
    • 77951766653 scopus 로고    scopus 로고
    • Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals
    • doi:10.1093/ije/dyp288
    • Lips, E. H., Gaborieau, V., McKay, J. D., Chabrier, A., Hung, R. J., Boffetta, P., et al. (2009). Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. International Journal of Epidemiology, 39, 563-577. doi:10.1093/ije/dyp288.
    • (2009) International Journal of Epidemiology , vol.39 , pp. 563-577
    • Lips, E.H.1    Gaborieau, V.2    McKay, J.D.3    Chabrier, A.4    Hung, R.J.5    Boffetta, P.6
  • 31
    • 77951751034 scopus 로고    scopus 로고
    • Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    • doi:10.1038/ng.572
    • Liu, J. Z., Tozzi, F., Waterworth, D. M., Pillai, S. G., Muglia, P., Middleton, L., et al. (2010). Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nature Genetics, 42, 436-440. doi:10.1038/ng.572.
    • (2010) Nature Genetics , vol.42 , pp. 436-440
    • Liu, J.Z.1    Tozzi, F.2    Waterworth, D.M.3    Pillai, S.G.4    Muglia, P.5    Middleton, L.6
  • 32
    • 52449127998 scopus 로고    scopus 로고
    • Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer
    • doi:10.1093/jnci/djn268
    • Liu, P., Vikis, H. G., Wang, D., Lu, Y., Wang, Y., Schwartz, A. G., et al. (2008). Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. Journal of the National Cancer Institute, 100, 1326-1330. doi:10.1093/jnci/djn268.
    • (2008) Journal of the National Cancer Institute , vol.100 , pp. 1326-1330
    • Liu, P.1    Vikis, H.G.2    Wang, D.3    Lu, Y.4    Wang, Y.5    Schwartz, A.G.6
  • 33
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • doi:10.1371/journal.pmed.0030442
    • Mathers, C. D., & Loncar, D. (2006). Projections of global mortality and burden of disease from 2002 to 2030. PLoS Medicine, 3, 2011-2030. doi:10.1371/journal.pmed.0030442.
    • (2006) PLoS Medicine , vol.3 , pp. 2011-2030
    • Mathers, C.D.1    Loncar, D.2
  • 35
    • 9644288107 scopus 로고    scopus 로고
    • Assessing publication bias in genetic association studies: Evidence from a recent meta-analysis
    • doi:10.1016/j.psychres.2004.06.011
    • Munafo, M. R., Clark, T. G., & Flint, J. (2004). Assessing publication bias in genetic association studies: Evidence from a recent meta-analysis. Psychiatry Research, 129, 39-44. doi:10.1016/j.psychres.2004.06.011.
    • (2004) Psychiatry Research , vol.129 , pp. 39-44
    • Munafo, M.R.1    Clark, T.G.2    Flint, J.3
  • 36
    • 44149120764 scopus 로고    scopus 로고
    • Genes and cigarette smoking
    • doi:10.1111/j.1360-0443.2007.02071.x
    • Munafo, M. R., & Johnstone, E. C. (2008). Genes and cigarette smoking. Addiction, 103, 893-904. doi:10.1111/j.1360-0443.2007.02071.x.
    • (2008) Addiction , vol.103 , pp. 893-904
    • Munafo, M.R.1    Johnstone, E.C.2
  • 37
    • 63449101907 scopus 로고    scopus 로고
    • A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci
    • doi:10.1371/journal.pgen.1000421
    • Pillai, S. G., Ge, D., Zhu, G., Kong, X., Shianna, K. V., Need, A. C., et al. (2009). A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci. PLoS Genetics, 5, e1000421. doi:10.1371/journal.pgen.1000421.
    • (2009) PLoS Genetics , vol.5
    • Pillai, S.G.1    Ge, D.2    Zhu, G.3    Kong, X.4    Shianna, K.V.5    Need, A.C.6
  • 38
    • 77951110826 scopus 로고    scopus 로고
    • Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence
    • doi:10.1038/npp.2010.7
    • Ray, R., Mitra, N., Baldwin, D., Guo, M., Patterson, F., Heitjan, D. F., et al. (2010). Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence. Neuropsychopharmacology, 35, 1374-1382. doi:10.1038/npp.2010.7.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1374-1382
    • Ray, R.1    Mitra, N.2    Baldwin, D.3    Guo, M.4    Patterson, F.5    Heitjan, D.F.6
  • 39
    • 40349116471 scopus 로고    scopus 로고
    • Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function
    • doi:10.1111/j.1601-183X.2007.00329.x
    • Rigbi, A., Kanyas, K., Yakir, A., Greenbaum, L., Pollak, Y., Ben-Asher, E., et al. (2008). Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function. Genes, Brain and Behavior, 7, 164-172. doi:10.1111/j.1601-183X.2007.00329.x.
    • (2008) Genes, Brain and Behavior , vol.7 , pp. 164-172
    • Rigbi, A.1    Kanyas, K.2    Yakir, A.3    Greenbaum, L.4    Pollak, Y.5    Ben-Asher, E.6
  • 40
    • 77957366301 scopus 로고    scopus 로고
    • Multiple independent loci at chromosome 15q25.1 affect smoking quantity: A meta-analysis and comparison with lung cancer and COPD
    • doi:10.1371/journal.pgen.1001053
    • Saccone, N. L., Culverhouse, R. C., Schwantes-An, T. H., Cannon, D. S., Chen, X., Cichon, S., et al. (2010). Multiple independent loci at chromosome 15q25.1 affect smoking quantity: A meta-analysis and comparison with lung cancer and COPD. PLoS Genetics, 6, e1001053. doi:10.1371/journal.pgen.1001053.
    • (2010) PLoS Genetics , vol.6
    • Saccone, N.L.1    Culverhouse, R.C.2    Schwantes-An, T.H.3    Cannon, D.S.4    Chen, X.5    Cichon, S.6
  • 41
    • 70149090145 scopus 로고    scopus 로고
    • The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans
    • doi:10.1158/0008-5472.CAN-09-0786
    • Saccone, N. L., Wang, J. C., Breslau, N., Johnson, E. O., Hatsukami, D., Saccone, S. F., et al. (2009). The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. Cancer Research, 69, 6848-6856. doi:10.1158/0008-5472.CAN-09-0786.
    • (2009) Cancer Research , vol.69 , pp. 6848-6856
    • Saccone, N.L.1    Wang, J.C.2    Breslau, N.3    Johnson, E.O.4    Hatsukami, D.5    Saccone, S.F.6
  • 42
    • 33846510020 scopus 로고    scopus 로고
    • Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
    • doi:10.1093/hmg/ddl438
    • Saccone, S. F., Hinrichs, A. L., Saccone, N. L., Chase, G. A., Konvicka, K., Madden, P. A. F., et al. (2007). Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Human Molecular Genetics, 16, 36-49. doi:10.1093/hmg/ddl438.
    • (2007) Human Molecular Genetics , vol.16 , pp. 36-49
    • Saccone, S.F.1    Hinrichs, A.L.2    Saccone, N.L.3    Chase, G.A.4    Konvicka, K.5    Madden, P.A.F.6
  • 43
    • 70349673850 scopus 로고    scopus 로고
    • Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer
    • doi:10.1097/JTO.0b013e3181b244ef
    • Schwartz, A. G., Cote, M. L., Wenzlaff, A. S., Land, S., & Amos, C. I. (2009). Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer. Journal of Thoracic Oncology, 4, 1195-1201. doi:10.1097/JTO.0b013e3181b244ef.
    • (2009) Journal of Thoracic Oncology , vol.4 , pp. 1195-1201
    • Schwartz, A.G.1    Cote, M.L.2    Wenzlaff, A.S.3    Land, S.4    Amos, C.I.5
  • 44
    • 49249131512 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking
    • doi:10.1111/j.1360-0443.2008.02279.x
    • Sherva, R., Wilhelmsen, K., Pomerleau, C. S., Chasse, S. A., Rice, J. P., Snedecor, S. M., et al. (2008). Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. Addiction, 103, 1544-1552. doi:10.1111/j.1360-0443.2008.02279.x.
    • (2008) Addiction , vol.103 , pp. 1544-1552
    • Sherva, R.1    Wilhelmsen, K.2    Pomerleau, C.S.3    Chasse, S.A.4    Rice, J.P.5    Snedecor, S.M.6
  • 45
    • 58949096687 scopus 로고    scopus 로고
    • Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese
    • doi:10.1093/carcin/bgn257
    • Shiraishi, K., Kohno, T., Kunitoh, H., Watanabe, S. I., Goto, K., Nishiwaki, Y., et al. (2009). Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese. Carcinogenesis, 30, 65-70. doi:10.1093/carcin/bgn257.
    • (2009) Carcinogenesis , vol.30 , pp. 65-70
    • Shiraishi, K.1    Kohno, T.2    Kunitoh, H.3    Watanabe, S.I.4    Goto, K.5    Nishiwaki, Y.6
  • 46
    • 55749093830 scopus 로고    scopus 로고
    • The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer
    • doi:10.1093/jnci/djn363
    • Spitz, M. R., Amos, C. I., Dong, Q., Lin, J., & Wu, X. (2008). The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. Journal of the National Cancer Institute, 100, 1552-1556. doi:10.1093/jnci/djn363.
    • (2008) Journal of the National Cancer Institute , vol.100 , pp. 1552-1556
    • Spitz, M.R.1    Amos, C.I.2    Dong, Q.3    Lin, J.4    Wu, X.5
  • 48
    • 0033301678 scopus 로고    scopus 로고
    • The genetic epidemiology of smoking
    • doi:10.1080/14622299050011811
    • Sullivan, P. F., & Kendler, K. S. (1999). The genetic epidemiology of smoking. Nicotine & Tobacco Research, 1(Suppl. 2), S51-S57. doi:10.1080/14622299050011811.
    • (1999) Nicotine & Tobacco Research , vol.1 , Issue.SUPPL. 2
    • Sullivan, P.F.1    Kendler, K.S.2
  • 49
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • doi:10.1038/nature06846
    • Thorgeirsson, T. E., Geller, F., Sulem, P., Rafnar, T., Wiste, A., Magnusson, K. P., et al. (2008). A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature, 452, 638-642. doi:10.1038/nature06846.
    • (2008) Nature , vol.452 , pp. 638-642
    • Thorgeirsson, T.E.1    Geller, F.2    Sulem, P.3    Rafnar, T.4    Wiste, A.5    Magnusson, K.P.6
  • 50
    • 77951748276 scopus 로고    scopus 로고
    • Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
    • doi:10.1038/ng.573
    • Thorgeirsson, T. E., Gudbjartsson, D. F., Surakka, I., Vink, J. M., Amin, N., Geller, F., et al. (2010). Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nature Genetics, 42, 448-453. doi:10.1038/ng.573.
    • (2010) Nature Genetics , vol.42 , pp. 448-453
    • Thorgeirsson, T.E.1    Gudbjartsson, D.F.2    Surakka, I.3    Vink, J.M.4    Amin, N.5    Geller, F.6
  • 51
    • 77951765427 scopus 로고    scopus 로고
    • Commentary: Gene-environment interactions and smoking-related cancers
    • doi:10.1093/ije/dyp385
    • Thorgeirsson, T. E., & Stefansson, K. (2010). Commentary: Gene-environment interactions and smoking-related cancers. International Journal of Epidemiology, 39, 577-579. doi:10.1093/ije/dyp385.
    • (2010) International Journal of Epidemiology , vol.39 , pp. 577-579
    • Thorgeirsson, T.E.1    Stefansson, K.2
  • 52
    • 48249105897 scopus 로고    scopus 로고
    • A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction
    • doi:10.1371/journal.pgen.1000125
    • Weiss, R. B., Baker, T. B., Cannon, D. S., Von Niederhausern, A., Dunn, D. M., Matsunami, N., et al. (2008). A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS Genetics, 4, e1000125. doi:10.1371/journal.pgen.1000125.
    • (2008) PLoS Genetics , vol.4
    • Weiss, R.B.1    Baker, T.B.2    Cannon, D.S.3    Von Niederhausern, A.4    Dunn, D.M.5    Matsunami, N.6
  • 53
    • 44949092499 scopus 로고    scopus 로고
    • World Health Organization. Geneva, Switzerland: Author. Retrieved from
    • World Health Organization. (2008). WHO Report on the Global Tobacco Epidemic, 2008: The MPOWER package. Geneva, Switzerland: Author. Retrieved from http://www.who.int/en/.
    • (2008) WHO Report on the Global Tobacco Epidemic
  • 54
    • 67449119418 scopus 로고    scopus 로고
    • Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations
    • doi:10.1158/0008-5472.CAN-09-0081
    • Wu, C., Hu, Z., Yu, D., Huang, L., Jin, G., Liang, J., et al. (2009). Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Research, 69, 5065-5072. doi:10.1158/0008-5472.CAN-09-0081.
    • (2009) Cancer Research , vol.69 , pp. 5065-5072
    • Wu, C.1    Hu, Z.2    Yu, D.3    Huang, L.4    Jin, G.5    Liang, J.6
  • 55
  • 56
    • 58849140039 scopus 로고    scopus 로고
    • Lung cancer gene associated with COPD: Triple whammy or possible confounding effect?
    • doi:10.1183/09031936.00093908
    • Young, R. P., Hopkins, R. J., Hay, B. A., Epton, M. J., Black, P. N., & Gamble, G. D. (2008). Lung cancer gene associated with COPD: Triple whammy or possible confounding effect? European Respiratory Journal, 32, 1158-1164. doi:10.1183/09031936.00093908.
    • (2008) European Respiratory Journal , vol.32 , pp. 1158-1164
    • Young, R.P.1    Hopkins, R.J.2    Hay, B.A.3    Epton, M.J.4    Black, P.N.5    Gamble, G.D.6
  • 57
    • 70349682910 scopus 로고    scopus 로고
    • A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers
    • doi:10.1136/pgmj.2008.077107
    • Young, R. P., Hopkins, R. J., Hay, B. A., Epton, M. J., Mills, G. D., Black, P. N., et al. (2009). A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers. Postgraduate Medical Journal, 85, 515-524. doi:10.1136/pgmj.2008.077107.
    • (2009) Postgraduate Medical Journal , vol.85 , pp. 515-524
    • Young, R.P.1    Hopkins, R.J.2    Hay, B.A.3    Epton, M.J.4    Mills, G.D.5    Black, P.N.6
  • 58
    • 69449090136 scopus 로고    scopus 로고
    • The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung
    • doi:10.1093/carcin/bgp131
    • Zienolddiny, S., Skaug, V., Landvik, N. E., Ryberg, D., Phillips, D. H., Houlston, R., et al. (2009). The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung. Carcinogenesis, 30, 1368-1371. doi:10.1093/carcin/bgp131
    • (2009) Carcinogenesis , vol.30 , pp. 1368-1371
    • Zienolddiny, S.1    Skaug, V.2    Landvik, N.E.3    Ryberg, D.4    Phillips, D.H.5    Houlston, R.6


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