Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic

Cancer Immunology, Immunotherapy

Volumn 65, Issue 3, 2016, Pages 247-259

  Majchrzak, Kinga ^a,b   Nelson, Michelle H ^a   Bailey, Stefanie R ^a   Bowers, Jacob S ^a   Yu, Xue Zhong ^a   Rubinstein, Mark P ^a   Himes, Richard A ^c   Paulos, Chrystal M ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^c School of Business and Economics   (United States)

Author keywords

ACT; Cancer; Immunotherapy; Tc17; Th17

Indexed keywords

CD137 LIGAND; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; PROTEIN KINASE B INHIBITOR; ICOS PROTEIN, HUMAN; IL17A PROTEIN, HUMAN;

ANTIGEN PRESENTING CELL; CANCER IMMUNOTHERAPY; CANCER PATIENT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; HUMAN; IL 17 PRODUCING CD8 CYTOTOXIC T CELL; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOSTIMULATION; MEMORY T LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TUMOR IMMUNITY; BIOSYNTHESIS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOTHERAPY; NEOPLASMS; PHYSIOLOGY;

CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; INTERLEUKIN-12; INTERLEUKIN-17; NEOPLASMS; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84959481142     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-016-1797-6     Document Type: Review

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