NLRP3 inflammasome activation mediates estrogen deficiency-induced depression- and anxiety-like behavior and hippocampal inflammation in mice

Brain, Behavior, and Immunity

Volumn 56, Issue , 2016, Pages 175-186

  Xu, Yongjun ^a   Sheng, Hui ^a   Bao, Qingyue ^a   Wang, Yujun ^b   Lu, Jianqiang ^b   Ni, Xin ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF SPORT   (China)

Author keywords

Anxiety; Depression; Estrogen; Hippocampus; Inflammation; NLRP3 inflammasome

Indexed keywords

BELNACASAN; CRYOPYRIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PURINERGIC P2X7 RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; ESTROGEN; NLRP3 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; DISEASE COURSE; ENCEPHALITIS; ESTROGEN ACTIVITY; ESTROGEN DEFICIENCY; FEMALE; HIPPOCAMPUS; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OVARIECTOMY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; ANIMAL BEHAVIOR; ANXIETY; C57BL MOUSE; DEFICIENCY; IMMUNOLOGY; INFLAMMATION; METABOLISM; PHYSIOLOGY;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; DEPRESSION; ESTROGENS; FEMALE; HIPPOCAMPUS; INFLAMMASOMES; INFLAMMATION; MICE; MICE, INBRED C57BL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OVARIECTOMY;

EID: 84959441405     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2016.02.022     Document Type: Article

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