-
1
-
-
84859847698
-
27-Hydroxycholesterol: does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols
-
[1] Fakheri, R.J., Javitt, N.B., 27-Hydroxycholesterol: does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols. Steroids 77:6 (2012), 575–577.
-
(2012)
Steroids
, vol.77
, Issue.6
, pp. 575-577
-
-
Fakheri, R.J.1
Javitt, N.B.2
-
2
-
-
66349136255
-
Are side-chain oxidized oxysterols regulators also in vivo?
-
[2] Bjorkhem, I., Are side-chain oxidized oxysterols regulators also in vivo?. J. Lipid Res. 50:Suppl (2009), S213–S218.
-
(2009)
J. Lipid Res.
, vol.50
, pp. S213-S218
-
-
Bjorkhem, I.1
-
3
-
-
0036096897
-
Oxysterols: friends, foes, or just fellow passengers?
-
[3] Bjorkhem, I., Diczfalusy, U., Oxysterols: friends, foes, or just fellow passengers?. Arteriosclerosis Thrombosis Vasc. Biol. 22:5 (2002), 734–742.
-
(2002)
Arteriosclerosis Thrombosis Vasc. Biol.
, vol.22
, Issue.5
, pp. 734-742
-
-
Bjorkhem, I.1
Diczfalusy, U.2
-
4
-
-
0037072799
-
Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model: evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis
-
[4] Meir, K., et al. Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model: evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis. J. Biol. Chem. 277:37 (2002), 34036–34041.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.37
, pp. 34036-34041
-
-
Meir, K.1
-
5
-
-
80052965098
-
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo
-
[5] Shafaati, M., et al. Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J. Internal Med. 270:4 (2011), 377–387.
-
(2011)
J. Internal Med.
, vol.270
, Issue.4
, pp. 377-387
-
-
Shafaati, M.1
-
6
-
-
0038265008
-
Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover
-
[6] Lund, E.G., et al. Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover. J. Biol. Chem. 278:25 (2003), 22980–22988.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.25
, pp. 22980-22988
-
-
Lund, E.G.1
-
7
-
-
0032511035
-
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene
-
[7] Rosen, H., et al. Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. J. Biol. Chem. 273:24 (1998), 14805–14812.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.24
, pp. 14805-14812
-
-
Rosen, H.1
-
8
-
-
0034595445
-
Disruption of the oxysterol 7alpha-hydroxylase gene in mice
-
[8] Li-Hawkins, J., et al. Disruption of the oxysterol 7alpha-hydroxylase gene in mice. J. Biol. Chem. 275:22 (2000), 16536–16542.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.22
, pp. 16536-16542
-
-
Li-Hawkins, J.1
-
9
-
-
0034671509
-
Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding
-
[9] Repa, J.J., et al. Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding. J. Biol. Chem. 275:50 (2000), 39685–39692.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.50
, pp. 39685-39692
-
-
Repa, J.J.1
-
10
-
-
0033524420
-
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
-
[10] Janowski, B.A., et al. Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. Proc. Nat. Acad. Sci. U. S. A. 96:1 (1999), 266–271.
-
(1999)
Proc. Nat. Acad. Sci. U. S. A.
, vol.96
, Issue.1
, pp. 266-271
-
-
Janowski, B.A.1
-
11
-
-
33845587711
-
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
-
[11] Chen, W., et al. Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab. 5:1 (2007), 73–79.
-
(2007)
Cell Metab.
, vol.5
, Issue.1
, pp. 73-79
-
-
Chen, W.1
-
12
-
-
84910072898
-
27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice
-
[12] Heverin, M., et al. 27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice. Behav. Brain Res. 278 (2015), 356–359.
-
(2015)
Behav. Brain Res.
, vol.278
, pp. 356-359
-
-
Heverin, M.1
-
13
-
-
84875852287
-
On the regulatory role of side-chain hydroxylated oxysterols in the brain: lessons from CYP27A1 transgenic and Cyp27a1(-/-) mice
-
[13] Ali, Z., et al. On the regulatory role of side-chain hydroxylated oxysterols in the brain: lessons from CYP27A1 transgenic and Cyp27a1(-/-) mice. J. Lipid Res. 54:4 (2013), 1033–1043.
-
(2013)
J. Lipid Res.
, vol.54
, Issue.4
, pp. 1033-1043
-
-
Ali, Z.1
-
14
-
-
0001021338
-
Lipoprotein Analysis: a Practical Approach
-
C.A. Converse E. Roy Skinner Oxford University Press New York
-
[14] Bengtsson-Olivecrona, G., Olivecrona, T., Lipoprotein Analysis: a Practical Approach. Converse, C.A., Roy Skinner, E., (eds.), 1992, Oxford University Press, New York.
-
(1992)
-
-
Bengtsson-Olivecrona, G.1
Olivecrona, T.2
-
15
-
-
67649197416
-
Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells
-
[15] Acimovic, J., et al. Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells. J. Chromatogr. B 877:22 (2009), 2081–2086.
-
(2009)
J. Chromatogr. B
, vol.877
, Issue.22
, pp. 2081-2086
-
-
Acimovic, J.1
-
16
-
-
0028816863
-
Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry
-
[16] Dzeletovic, S., et al. Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry. Anal. Biochem. 225:1 (1995), 73–80.
-
(1995)
Anal. Biochem.
, vol.225
, Issue.1
, pp. 73-80
-
-
Dzeletovic, S.1
-
17
-
-
0033779953
-
24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A)
-
[17] Norlin, M., et al. 24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A). J. Lipid Res. 41:10 (2000), 1629–1639.
-
(2000)
J. Lipid Res.
, vol.41
, Issue.10
, pp. 1629-1639
-
-
Norlin, M.1
-
18
-
-
0034595650
-
Expression cloning of an oxysterol 7 alpha-hydroxylase selective for 24-hydroxycholesterol
-
[18] Li-Hawkins, J., et al. Expression cloning of an oxysterol 7 alpha-hydroxylase selective for 24-hydroxycholesterol. J. Biol. Chem. 275:22 (2000), 16543–16549.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.22
, pp. 16543-16549
-
-
Li-Hawkins, J.1
-
19
-
-
0029055367
-
Low density lipoprotein (LDL) cholesterol is converted to 27-hydroxycholesterol in human fibroblasts. Evidence that 27-hydroxycholesterol can be an important intracellular mediator between LDL and the suppression of cholesterol production
-
[19] Axelson, M., Larsson, O., Low density lipoprotein (LDL) cholesterol is converted to 27-hydroxycholesterol in human fibroblasts. Evidence that 27-hydroxycholesterol can be an important intracellular mediator between LDL and the suppression of cholesterol production. J. Biol. Chem. 270:25 (1995), 15102–15110.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.25
, pp. 15102-15110
-
-
Axelson, M.1
Larsson, O.2
-
20
-
-
0342316532
-
Oxysterols: modulators of cholesterol metabolism and other processes
-
[20] Schroepfer, G.J. Jr., Oxysterols: modulators of cholesterol metabolism and other processes. Physiol. Rev. 80:1 (2000), 361–554.
-
(2000)
Physiol. Rev.
, vol.80
, Issue.1
, pp. 361-554
-
-
Schroepfer, G.J.1
-
21
-
-
0018079091
-
Biological activity of some oxygenated sterols
-
[21] Kandutsch, A.A., Chen, H.W., Heiniger, H.J., Biological activity of some oxygenated sterols. Science 201:4355 (1978), 498–501.
-
(1978)
Science
, vol.201
, Issue.4355
, pp. 498-501
-
-
Kandutsch, A.A.1
Chen, H.W.2
Heiniger, H.J.3
-
22
-
-
0026439428
-
Evidence that 24- and 27-hydroxylation are not involved in the cholesterol-induced down-regulation of hydroxymethylglutaryl-CoA reductase in mouse liver
-
[22] Lund, E., Breuer, O., Bjorkhem, I., Evidence that 24- and 27-hydroxylation are not involved in the cholesterol-induced down-regulation of hydroxymethylglutaryl-CoA reductase in mouse liver. J. Biol. Chem. 267:35 (1992), 25092–25097.
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.35
, pp. 25092-25097
-
-
Lund, E.1
Breuer, O.2
Bjorkhem, I.3
-
23
-
-
84891380201
-
Characterization of cholesterol homeostasis in telomerase-immortalized tangier disease fibroblasts reveals marked phenotype variability
-
[23] Kannenberg, F.et al., Characterization of cholesterol homeostasis in telomerase-immortalized tangier disease fibroblasts reveals marked phenotype variability. J. Biol. Chem., 2013.
-
(2013)
J. Biol. Chem.
-
-
Kannenberg, F.E.A.1
-
24
-
-
33847699765
-
Activation of LXRs prevents bile acid toxicity and cholestasis in female mice
-
[24] Uppal, H., et al. Activation of LXRs prevents bile acid toxicity and cholestasis in female mice. Hepatology 45:2 (2007), 422–432.
-
(2007)
Hepatology
, vol.45
, Issue.2
, pp. 422-432
-
-
Uppal, H.1
-
25
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors: LXRalpha and LXRbeta
-
[25] Repa, J.J., et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors: LXRalpha and LXRbeta. Genes Dev. 14:22 (2000), 2819–2830.
-
(2000)
Genes Dev.
, vol.14
, Issue.22
, pp. 2819-2830
-
-
Repa, J.J.1
-
26
-
-
0036795623
-
Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism
-
[26] Kim, H.J., Miyazaki, M., Ntambi, J.M., Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism. J. Lipid Res. 43:10 (2002), 1750–1757.
-
(2002)
J. Lipid Res.
, vol.43
, Issue.10
, pp. 1750-1757
-
-
Kim, H.J.1
Miyazaki, M.2
Ntambi, J.M.3
-
27
-
-
34548017357
-
Effect of an enriched cholesterol diet during gestation on fatty acid synthase: HMG-CoA reductase and SREBP-1/2 expressions in rabbits
-
[27] Marseille-Tremblay, C., et al. Effect of an enriched cholesterol diet during gestation on fatty acid synthase: HMG-CoA reductase and SREBP-1/2 expressions in rabbits. Life Sci. 81:9 (2007), 772–778.
-
(2007)
Life Sci.
, vol.81
, Issue.9
, pp. 772-778
-
-
Marseille-Tremblay, C.1
-
28
-
-
77149145830
-
The mechanism of dietary cholesterol effects on lipids metabolism in rats
-
[28] Wang, Y.M., et al. The mechanism of dietary cholesterol effects on lipids metabolism in rats. Lipids Health Dis., 9, 2010, p4.
-
(2010)
Lipids Health Dis.
, vol.9
, pp. p4
-
-
Wang, Y.M.1
-
29
-
-
35148813852
-
Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol
-
[29] Heverin, M., et al. Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol. Arteriosclerosis Thrombosis Vasc. Biol. 27:10 (2007), 2191–2197.
-
(2007)
Arteriosclerosis Thrombosis Vasc. Biol.
, vol.27
, Issue.10
, pp. 2191-2197
-
-
Heverin, M.1
-
30
-
-
33846208252
-
The nuclear receptor LXR is a glucose sensor
-
[30] Mitro, N., et al. The nuclear receptor LXR is a glucose sensor. Nature 445:7124 (2007), 219–223.
-
(2007)
Nature
, vol.445
, Issue.7124
, pp. 219-223
-
-
Mitro, N.1
-
31
-
-
84867031028
-
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses
-
[31] Spann, N.J., et al. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell 151:1 (2012), 138–152.
-
(2012)
Cell
, vol.151
, Issue.1
, pp. 138-152
-
-
Spann, N.J.1
-
32
-
-
33748792007
-
Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands
-
[32] Yang, C., et al. Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. J. Biol. Chem. 281:38 (2006), 27816–27826.
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.38
, pp. 27816-27826
-
-
Yang, C.1
|