Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis

Journal of Biological Chemistry

Volumn 277, Issue 37, 2002, Pages 34036-34041

  Meir, Karen ^a,b,c,d   Kitsberg, Daniel ^a,b,c,d   Alkalay, Irit ^a,b,c,d   Szafer, Fanny ^a,b,c,d   Rosen, Haim ^a,b,c,d   Shpitzen, Shoshanna ^a,b,c,d   Avi, Liat Ben ^a,b,c,d   Staels, Bart ^a,b,c,d   Fievet, Catherine ^a,b,c,d   Meiner, Vardiella ^a,b,c,d   Björkhem, Ingemar ^a,b,c,d   Leitersdorf, Eran ^a,b,c,d  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c INSTITUT PASTEUR DE LILLE   (France)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CHOLESTEROL; CLONING; DNA; MORPHOLOGY;

HOMEOSTASIS;

BIOCHEMISTRY;

BILE ACID; CHOLESTEROL; COMPLEMENTARY DNA; DNA; STEROID; STEROL 27 HYDROXYLASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CHOLESTEROL METABOLISM; CONTROLLED STUDY; GENE OVEREXPRESSION; GENOTYPE; IMMUNOBLOTTING; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BILE; BILE ACIDS AND SALTS; CHOLESTEROL; CYTOCHROME P-450 CYP27A1; DIETARY FATS; FECES; FEMALE; HOMEOSTASIS; HUMANS; LIPIDS; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; STEROID HYDROXYLASES;

ANIMALIA; MUS MUSCULUS; VECTORS;

EID: 0037072799     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M201122200     Document Type: Article

References (32)