메뉴 건너뛰기




Volumn 35, Issue 1, 2016, Pages

Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors

Author keywords

Cellular signaling; Clinicopathology; Gastric cancer; Metastasis; Neuropilin 1; Proliferation

Indexed keywords

BROXURIDINE; CYCLIN DEPENDENT KINASE 2; CYCLIN E; EPIDERMAL GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE 2; MEMBRANE PROTEIN; NEUROPILIN 1; PROTEIN P27; SHORT HAIRPIN RNA; VASCULOTROPIN 165; C REACTIVE PROTEIN; NERVE PROTEIN; NEURONAL PENTRAXIN;

EID: 84959332688     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-016-0291-5     Document Type: Article
Times cited : (70)

References (33)
  • 1
    • 84868616455 scopus 로고    scopus 로고
    • Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity
    • 3660061 22948112
    • Prud'homme GJ, Glinka Y. Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity. Oncotarget. 2012;3:921-39.
    • (2012) Oncotarget , vol.3 , pp. 921-939
    • Prud'homme, G.J.1    Glinka, Y.2
  • 2
    • 79957918593 scopus 로고    scopus 로고
    • Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling
    • 21338642
    • Bergé M, Allanic D, Bonnin P, de Montrion C, Richard J, Suc M, et al. Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling. J Hepatol. 2011;55:866-75.
    • (2011) J Hepatol , vol.55 , pp. 866-875
    • Bergé, M.1    Allanic, D.2    Bonnin, P.3    De Montrion, C.4    Richard, J.5    Suc, M.6
  • 3
    • 84876810591 scopus 로고    scopus 로고
    • Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer
    • 23551578
    • Staton CA, Koay I, Wu JM, Hoh L, Reed MW, Brown NJ. Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer. Histopathology. 2013;62:908-15.
    • (2013) Histopathology , vol.62 , pp. 908-915
    • Staton, C.A.1    Koay, I.2    Wu, J.M.3    Hoh, L.4    Reed, M.W.5    Brown, N.J.6
  • 4
    • 84894301298 scopus 로고    scopus 로고
    • Neuropilin-1 expression in squamous cell carcinoma of the oesophagus
    • 23956271
    • Alattar M, Omo A, Elsharawy M, Li J. Neuropilin-1 expression in squamous cell carcinoma of the oesophagus. Eur J Cardiothorac Surg. 2014;45:514-20.
    • (2014) Eur J Cardiothorac Surg , vol.45 , pp. 514-520
    • Alattar, M.1    Omo, A.2    Elsharawy, M.3    Li, J.4
  • 5
    • 33845991161 scopus 로고    scopus 로고
    • Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
    • 1:CAS:528:DC%2BD2sXhtFClsLk%3D 17222790
    • Pan Q, Chanthery Y, Liang WC, Stawicki S, Mak J, Rathore N, et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell. 2007;11:53-67.
    • (2007) Cancer Cell , vol.11 , pp. 53-67
    • Pan, Q.1    Chanthery, Y.2    Liang, W.C.3    Stawicki, S.4    Mak, J.5    Rathore, N.6
  • 6
    • 76349096681 scopus 로고    scopus 로고
    • Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
    • 2822953 1:CAS:528:DC%2BC3cXhsVSrsrY%3D 20087344
    • Jia H, Cheng L, Tickner M, Bagherzadeh A, Selwood D, Zachary I. Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity. Br J Cancer. 2010;102:541-52.
    • (2010) Br J Cancer , vol.102 , pp. 541-552
    • Jia, H.1    Cheng, L.2    Tickner, M.3    Bagherzadeh, A.4    Selwood, D.5    Zachary, I.6
  • 7
    • 77951622512 scopus 로고    scopus 로고
    • Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo
    • 1:CAS:528:DC%2BC3cXhs1Omtbw%3D 20140015
    • Nasarre C, Roth M, Jacob L, Roth L, Koncina E, Thien A, et al. Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo. Oncogene. 2010;29:2381-92.
    • (2010) Oncogene , vol.29 , pp. 2381-2392
    • Nasarre, C.1    Roth, M.2    Jacob, L.3    Roth, L.4    Koncina, E.5    Thien, A.6
  • 9
    • 84874760414 scopus 로고    scopus 로고
    • Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma
    • 3587980 1:CAS:528:DC%2BC3sXjsFeqsr0%3D 23452854
    • Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, et al. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. 2013;152:1065-76.
    • (2013) Cell , vol.152 , pp. 1065-1076
    • Snuderl, M.1    Batista, A.2    Kirkpatrick, N.D.3    Ruiz De Almodovar, C.4    Riedemann, L.5    Walsh, E.C.6
  • 10
    • 84860356630 scopus 로고    scopus 로고
    • Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
    • 3302235 1:CAS:528:DC%2BC38XktFOnsLs%3D 22393126
    • Hamerlik P, Lathia JD, Rasmussen R, Wu Q, Bartkova J, Lee M, et al. Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J Exp Med. 2012;209:507-20.
    • (2012) J Exp Med , vol.209 , pp. 507-520
    • Hamerlik, P.1    Lathia, J.D.2    Rasmussen, R.3    Wu, Q.4    Bartkova, J.5    Lee, M.6
  • 11
    • 79961042374 scopus 로고    scopus 로고
    • VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation
    • 3145551 1:CAS:528:DC%2BC3MXhtValur%2FO 21653826
    • Herzog B, Pellet-Many C, Britton G, Hartzoulakis B, Zachary IC. VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation. Mol Biol Cell. 2011;22:2766-76.
    • (2011) Mol Biol Cell , vol.22 , pp. 2766-2776
    • Herzog, B.1    Pellet-Many, C.2    Britton, G.3    Hartzoulakis, B.4    Zachary, I.C.5
  • 12
    • 84926641854 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer
    • 4392793 25889301
    • Barr MP, Gray SG, Gately K, Hams E, Fallon PG, Davies AM, et al. Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer. Mol Cancer. 2015;14:45.
    • (2015) Mol Cancer , vol.14 , pp. 45
    • Barr, M.P.1    Gray, S.G.2    Gately, K.3    Hams, E.4    Fallon, P.G.5    Davies, A.M.6
  • 13
  • 14
    • 35948964766 scopus 로고    scopus 로고
    • Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1
    • 1:CAS:528:DC%2BD2sXht1erurzI 17974973
    • Matsushita A, Götze T, Korc M. Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1. Cancer Res. 2007;67:10309-16.
    • (2007) Cancer Res , vol.67 , pp. 10309-10316
    • Matsushita, A.1    Götze, T.2    Korc, M.3
  • 15
    • 0037429570 scopus 로고    scopus 로고
    • Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells
    • 2376351 1:CAS:528:DC%2BD3sXhs1CrsLs%3D 12618892
    • Akagi M, Kawaguchi M, Liu W, McCarty MF, Takeda A, Fan F, et al. Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells. Br J Cancer. 2003;88:796-802.
    • (2003) Br J Cancer , vol.88 , pp. 796-802
    • Akagi, M.1    Kawaguchi, M.2    Liu, W.3    McCarty, M.F.4    Takeda, A.5    Fan, F.6
  • 16
    • 84892713518 scopus 로고    scopus 로고
    • Angiogenesis in gastric cancer: Hitting the target?
    • 24094766
    • Ilson DH. Angiogenesis in gastric cancer: Hitting the target? Lancet. 2014;383:4-6.
    • (2014) Lancet , vol.383 , pp. 4-6
    • Ilson, D.H.1
  • 17
    • 84895855915 scopus 로고    scopus 로고
    • Expression profiles of HER2, EGFR, MET and FGFR2 in a large cohort of patients with gastric adenocarcinoma
    • 1:CAS:528:DC%2BC2MXls1Wrt7Y%3D 24626858
    • Nagatsuma AK, Aizawa M, Kuwata T, Doi T, Ohtsu A, Fujii H, et al. Expression profiles of HER2, EGFR, MET and FGFR2 in a large cohort of patients with gastric adenocarcinoma. Gastric Cancer. 2015;18:227-38.
    • (2015) Gastric Cancer , vol.18 , pp. 227-238
    • Nagatsuma, A.K.1    Aizawa, M.2    Kuwata, T.3    Doi, T.4    Ohtsu, A.5    Fujii, H.6
  • 18
    • 84925270011 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-κB signaling pathway for gastric cancer metastasis
    • 1:CAS:528:DC%2BC2MXktFehur0%3D 25727320
    • Hao NB, Tang B, Wang GZ, Xie R, Hu CJ, Wang SM, et al. Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-κB signaling pathway for gastric cancer metastasis. Cancer Lett. 2015;361:57-66.
    • (2015) Cancer Lett , vol.361 , pp. 57-66
    • Hao, N.B.1    Tang, B.2    Wang, G.Z.3    Xie, R.4    Hu, C.J.5    Wang, S.M.6
  • 20
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): A phase 3, open-label, randomized controlled trial
    • 1:CAS:528:DC%2BC3cXhtVymt7zO 20728210
    • Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): A phase 3, open-label, randomized controlled trial. Lancet. 2010;376:687-97.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6
  • 22
    • 84891831293 scopus 로고    scopus 로고
    • Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer
    • 1:CAS:528:DC%2BC2cXosV2l 24165223
    • Sun XP, Dong X, Lin L, Jiang X, Wei Z, Zhai B, et al. Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer. FEBS J. 2014;281:115-28.
    • (2014) FEBS J , vol.281 , pp. 115-128
    • Sun, X.P.1    Dong, X.2    Lin, L.3    Jiang, X.4    Wei, Z.5    Zhai, B.6
  • 23
    • 84873307557 scopus 로고    scopus 로고
    • STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells
    • 1:CAS:528:DC%2BC3sXksVyqu7s%3D 23333463
    • Wei Z, Jiang X, Qiao H, Zhai B, Zhang L, Zhang Q, et al. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells. Cell Signal. 2013;25:931-8.
    • (2013) Cell Signal , vol.25 , pp. 931-938
    • Wei, Z.1    Jiang, X.2    Qiao, H.3    Zhai, B.4    Zhang, L.5    Zhang, Q.6
  • 24
    • 78751505998 scopus 로고    scopus 로고
    • P27: A barometer of signaling deregulation and potential predictor of response to targeted therapies
    • 3017239 1:CAS:528:DC%2BC3MXhtVensA%3D%3D 20966355
    • Wander SA, Zhao D, Slingerland JM. P27: A barometer of signaling deregulation and potential predictor of response to targeted therapies. Clin Cancer Res. 2011;17:12-8.
    • (2011) Clin Cancer Res , vol.17 , pp. 12-18
    • Wander, S.A.1    Zhao, D.2    Slingerland, J.M.3
  • 26
    • 84865658329 scopus 로고    scopus 로고
    • VEGF inhibition, hypertension, and renal toxicity
    • 3746763 1:CAS:528:DC%2BC38XpvVyku7g%3D 22544560
    • Hayman SR, Leung N, Grande JP, Garovic VD. VEGF inhibition, hypertension, and renal toxicity. Curr Oncol Rep. 2012;14:285-94.
    • (2012) Curr Oncol Rep , vol.14 , pp. 285-294
    • Hayman, S.R.1    Leung, N.2    Grande, J.P.3    Garovic, V.D.4
  • 27
    • 84876908762 scopus 로고    scopus 로고
    • Targeting VEGF signalling via the neuropilin co-receptor
    • 1:CAS:528:DC%2BC38XhvFWhsb7P 23228652
    • Djordjevic S, Driscoll PC. Targeting VEGF signalling via the neuropilin co-receptor. Drug Discov Today. 2013;18:447-55.
    • (2013) Drug Discov Today , vol.18 , pp. 447-455
    • Djordjevic, S.1    Driscoll, P.C.2
  • 28
    • 84892894930 scopus 로고    scopus 로고
    • Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function
    • 3897185 1:CAS:528:DC%2BC2cXht12ms7c%3D 24446483
    • Jean C, Chen XL, Nam JO, Tancioni I, Uryu S, Lawson C, et al. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. J Cell Biol. 2014;204:247-63.
    • (2014) J Cell Biol , vol.204 , pp. 247-263
    • Jean, C.1    Chen, X.L.2    Nam, J.O.3    Tancioni, I.4    Uryu, S.5    Lawson, C.6
  • 29
    • 84945933984 scopus 로고    scopus 로고
    • Integrin endosomal signalling suppresses anoikis
    • 10.1038/ncb3250 1:CAS:528:DC%2BC2MXhsFKqu7vJ 26436690
    • Alanko J, Mai A, Jacquemet G, Schauer K, Kaukonen R, Saari M, et al. Integrin endosomal signalling suppresses anoikis. Nat Cell Biol. 2015;17(11):1412-21. Doi: 10.1038/ncb3250.
    • (2015) Nat Cell Biol , vol.17 , Issue.11 , pp. 1412-1421
    • Alanko, J.1    Mai, A.2    Jacquemet, G.3    Schauer, K.4    Kaukonen, R.5    Saari, M.6
  • 30
    • 84982075664 scopus 로고    scopus 로고
    • VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells
    • 4582117 26209534
    • Yoshida A, Shimizu A, Asano H, Kadonosono T, Kondoh SK, Geretti E, et al. VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells. Biol Open. 2015;4:1063-76.
    • (2015) Biol Open , vol.4 , pp. 1063-1076
    • Yoshida, A.1    Shimizu, A.2    Asano, H.3    Kadonosono, T.4    Kondoh, S.K.5    Geretti, E.6
  • 31
    • 84923344806 scopus 로고    scopus 로고
    • Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks
    • 4268886 1:CAS:528:DC%2BC2MXksVeltbc%3D 25503978
    • Chakraborty S, Li L, Puliyappadamba VT, Guo G, Hatanpaa KJ, Mickey B, et al. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nat Commun. 2014;5:5811.
    • (2014) Nat Commun , vol.5 , pp. 5811
    • Chakraborty, S.1    Li, L.2    Puliyappadamba, V.T.3    Guo, G.4    Hatanpaa, K.J.5    Mickey, B.6
  • 33
    • 0036799377 scopus 로고    scopus 로고
    • PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
    • 1:CAS:528:DC%2BD38XnsVGrt70%3D 12244301
    • Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, et al. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med. 2002;8:1145-52.
    • (2002) Nat Med , vol.8 , pp. 1145-1152
    • Shin, I.1    Yakes, F.M.2    Rojo, F.3    Shin, N.Y.4    Bakin, A.V.5    Baselga, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.