메뉴 건너뛰기




Volumn 55, Issue 4, 2011, Pages 866-875

Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling

Author keywords

Angiogenesis; Hepatocellular carcinoma; Molecular targeted therapies; Neuropilin 1; Tumour vascular remodelling; Vascular endothelial growth factor

Indexed keywords

NEUROPILIN 1;

EID: 79957918593     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.01.033     Document Type: Article
Times cited : (82)

References (48)
  • 1
    • 40849124295 scopus 로고    scopus 로고
    • Novel advancements in the management of hepatocellular carcinoma in 2008
    • J.M. Llovet, and J. Bruix Novel advancements in the management of hepatocellular carcinoma in 2008 J Hepatol 48 2008 S20 S37
    • (2008) J Hepatol , vol.48
    • Llovet, J.M.1    Bruix, J.2
  • 3
    • 45849135992 scopus 로고    scopus 로고
    • Vascular changes in hepatocellular carcinoma
    • Z.F. Yang, and R.T. Poon Vascular changes in hepatocellular carcinoma Anat Rec (Hoboken) 291 2008 721 734
    • (2008) Anat Rec (Hoboken) , vol.291 , pp. 721-734
    • Yang, Z.F.1    Poon, R.T.2
  • 4
    • 70350507211 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in the management of hepatocellular carcinoma: A review of literature
    • A.O. Kaseb, A. Hanbali, M. Cotant, M.M. Hassan, I. Wollner, and P.A. Philip Vascular endothelial growth factor in the management of hepatocellular carcinoma: a review of literature Cancer 115 2009 4895 4906
    • (2009) Cancer , vol.115 , pp. 4895-4906
    • Kaseb, A.O.1    Hanbali, A.2    Cotant, M.3    Hassan, M.M.4    Wollner, I.5    Philip, P.A.6
  • 5
    • 58849136702 scopus 로고    scopus 로고
    • Molecular targeted therapy for hepatocellular carcinoma
    • M. Thomas Molecular targeted therapy for hepatocellular carcinoma J Gastroenterol 44 2009 136 141
    • (2009) J Gastroenterol , vol.44 , pp. 136-141
    • Thomas, M.1
  • 8
    • 41049086388 scopus 로고    scopus 로고
    • Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity
    • DOI 10.1182/blood-2007-04-084269
    • E. Sulpice, J. Plouet, M. Berge, D. Allanic, G. Tobelem, and T. Merkulova-Rainon Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity Blood 111 2008 2036 2045 (Pubitemid 351451514)
    • (2008) Blood , vol.111 , Issue.4 , pp. 2036-2045
    • Sulpice, E.1    Plouet, J.2    Berge, M.3    Allanic, D.4    Tobelem, G.5    Merkulova-Rainon, T.6
  • 9
    • 33750457687 scopus 로고    scopus 로고
    • Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1
    • DOI 10.1002/mc.20248
    • S. Banerjee, K. Sengupta, K. Dhar, S. Mehta, P.A. D'Amore, and G. Dhar Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1 Mol Carcinog 45 2006 871 880 (Pubitemid 44646339)
    • (2006) Molecular Carcinogenesis , vol.45 , Issue.11 , pp. 871-880
    • Banerjee, S.1    Sengupta, K.2    Dhar, K.3    Mehta, S.4    D'Amore, P.A.5    Dhar, G.6    Banerjee, S.K.7
  • 10
    • 46949088806 scopus 로고    scopus 로고
    • Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity
    • DOI 10.1189/jlb.0208090
    • Y. Glinka, and G.J. Prud'homme Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity J Leukoc Biol 84 2008 302 310 (Pubitemid 351960305)
    • (2008) Journal of Leukocyte Biology , vol.84 , Issue.1 , pp. 302-310
    • Glinka, Y.1    Prud'homme, G.J.2
  • 11
    • 77957787219 scopus 로고    scopus 로고
    • Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype
    • Y. Cao, A. Szabolcs, S.K. Dutta, U. Yaqoob, K. Jagavelu, and L. Wang Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype J Biol Chem 285 2010 31840 31848
    • (2010) J Biol Chem , vol.285 , pp. 31840-31848
    • Cao, Y.1    Szabolcs, A.2    Dutta, S.K.3    Yaqoob, U.4    Jagavelu, K.5    Wang, L.6
  • 12
    • 77954976056 scopus 로고    scopus 로고
    • Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells
    • S. Cao, U. Yaqoob, A. Das, U. Shergill, K. Jagavelu, and R.C. Huebert Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells J Clin Invest 120 2010 2379 2394
    • (2010) J Clin Invest , vol.120 , pp. 2379-2394
    • Cao, S.1    Yaqoob, U.2    Das, A.3    Shergill, U.4    Jagavelu, K.5    Huebert, R.C.6
  • 13
    • 77955225060 scopus 로고    scopus 로고
    • Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1
    • K. Dhar, G. Dhar, M. Majumder, I. Haque, S. Mehta, and P.J. Van Veldhuizen Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1 Mol Cancer 9 2010 209
    • (2010) Mol Cancer , vol.9 , pp. 209
    • Dhar, K.1    Dhar, G.2    Majumder, M.3    Haque, I.4    Mehta, S.5    Van Veldhuizen, P.J.6
  • 14
    • 33344474679 scopus 로고    scopus 로고
    • Neuropilins in neoplasms: Expression, regulation, and function
    • DOI 10.1016/j.yexcr.2005.11.024, PII S0014482705005550
    • D.R. Bielenberg, C.A. Pettaway, S. Takashima, and M. Klagsbrun Neuropilins in neoplasms: expression, regulation, and function Exp Cell Res 312 2006 584 593 (Pubitemid 43290335)
    • (2006) Experimental Cell Research , vol.312 , Issue.5 , pp. 584-593
    • Bielenberg, D.R.1    Pettaway, C.A.2    Takashima, S.3    Klagsbrun, M.4
  • 16
    • 0033766256 scopus 로고    scopus 로고
    • Expression and regulation of neuropilin-1 in human astrocytomas
    • H. Ding, X. Wu, L. Roncari, N. Lau, P. Shannon, and A. Nagy Expression and regulation of neuropilin-1 in human astrocytomas Int J Cancer 88 2000 584 592
    • (2000) Int J Cancer , vol.88 , pp. 584-592
    • Ding, H.1    Wu, X.2    Roncari, L.3    Lau, N.4    Shannon, P.5    Nagy, A.6
  • 18
    • 1442329388 scopus 로고    scopus 로고
    • Expression of Neuropilin-1 in High-grade Dysplasia, Invasive Cancer, and Metastases of the Human Gastrointestinal Tract
    • DOI 10.1097/00000478-200403000-00007
    • D.E. Hansel, R.E. Wilentz, C.J. Yeo, R.D. Schulick, E. Montgomery, and A. Maitra Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract Am J Surg Pathol 28 2004 347 356 (Pubitemid 38269568)
    • (2004) American Journal of Surgical Pathology , vol.28 , Issue.3 , pp. 347-356
    • Hansel, D.E.1    Wilentz, R.E.2    Yeo, C.J.3    Schulick, R.D.4    Montgomery, E.5    Maitra, A.6
  • 19
    • 0037110615 scopus 로고    scopus 로고
    • Neuropilin 1 and neuropilin 2 co-expression is significantly correlated with increased vascularity and poor prognosis in nonsmall cell lung carcinoma
    • DOI 10.1002/cncr.10936
    • T. Kawakami, T. Tokunaga, H. Hatanaka, H. Kijima, H. Yamazaki, and Y. Abe Neuropilin 1 and neuropilin 2 co-expression is significantly correlated with increased vascularity and poor prognosis in nonsmall cell lung carcinoma Cancer 95 2002 2196 2201 (Pubitemid 35253382)
    • (2002) Cancer , vol.95 , Issue.10 , pp. 2196-2201
    • Kawakami, T.1    Tokunaga, T.2    Hatanaka, H.3    Kijima, H.4    Yamazaki, H.5    Abe, Y.6    Osamura, Y.7    Inoue, H.8    Ueyama, Y.9    Nakamura, M.10
  • 23
    • 0037114642 scopus 로고    scopus 로고
    • In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo
    • DOI 10.1182/blood.V100.13.4622
    • G. Schuch, M. Machluf, G. Bartsch Jr., M. Nomi, H. Richard, and A. Atala In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo Blood 100 2002 4622 4628 (Pubitemid 35429707)
    • (2002) Blood , vol.100 , Issue.13 , pp. 4622-4628
    • Schuch, G.1    Machluf, M.2    Bartsch Jr., G.3    Nomi, M.4    Richard, H.5    Atala, A.6    Soker, S.7
  • 24
    • 36749058532 scopus 로고    scopus 로고
    • Combined Antiangiogenic Therapy is Superior to Single Inhibitors in a Model of Renal Cell Carcinoma
    • DOI 10.1016/j.juro.2007.08.086, PII S0022534707022781
    • G. Bartsch Jr., K. Eggert, S. Soker, C. Bokemeyer, R. Hautmann, and G. Schuch Combined antiangiogenic therapy is superior to single inhibitors in a model of renal cell carcinoma J Urol 179 2008 326 332 (Pubitemid 350216716)
    • (2008) Journal of Urology , vol.179 , Issue.1 , pp. 326-332
    • Bartsch Jr., G.1    Eggert, K.2    Soker, S.3    Bokemeyer, C.4    Hautmann, R.5    Schuch, G.6
  • 25
    • 33751091501 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1
    • DOI 10.1016/j.lfs.2006.08.005, PII S0024320506006084
    • A. Starzec, R. Vassy, A. Martin, M. Lecouvey, B.M. Di, and M. Crepin Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1 Life Sci 79 2006 2370 2381 (Pubitemid 44772930)
    • (2006) Life Sciences , vol.79 , Issue.25 , pp. 2370-2381
    • Starzec, A.1    Vassy, R.2    Martin, A.3    Lecouvey, M.4    Di Benedetto, M.5    Crepin, M.6    Perret, G.Y.7
  • 26
    • 76349096681 scopus 로고    scopus 로고
    • Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
    • H. Jia, L. Cheng, M. Tickner, A. Bagherzadeh, D. Selwood, and I. Zachary Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity Br J Cancer 102 2010 541 552
    • (2010) Br J Cancer , vol.102 , pp. 541-552
    • Jia, H.1    Cheng, L.2    Tickner, M.3    Bagherzadeh, A.4    Selwood, D.5    Zachary, I.6
  • 27
    • 77951622512 scopus 로고    scopus 로고
    • Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo
    • C. Nasarre, M. Roth, L. Jacob, L. Roth, E. Koncina, and A. Thien Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo Oncogene 29 2010 2381 2392
    • (2010) Oncogene , vol.29 , pp. 2381-2392
    • Nasarre, C.1    Roth, M.2    Jacob, L.3    Roth, L.4    Koncina, E.5    Thien, A.6
  • 29
    • 77949342169 scopus 로고    scopus 로고
    • Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction
    • A. Jarvis, C.K. Allerston, H. Jia, B. Herzog, A. Garza-Garcia, and N. Winfield Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction J Med Chem 53 2010 2215 2226
    • (2010) J Med Chem , vol.53 , pp. 2215-2226
    • Jarvis, A.1    Allerston, C.K.2    Jia, H.3    Herzog, B.4    Garza-Garcia, A.5    Winfield, N.6
  • 30
    • 13644267292 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cell modulation upon resection and shear stress in vitro
    • F. Braet, M. Shleper, M. Paizi, S. Brodsky, N. Kopeiko, and N. Resnick Liver sinusoidal endothelial cell modulation upon resection and shear stress in vitro Comp Hepatol 3 2004 7
    • (2004) Comp Hepatol , vol.3 , pp. 7
    • Braet, F.1    Shleper, M.2    Paizi, M.3    Brodsky, S.4    Kopeiko, N.5    Resnick, N.6
  • 31
    • 76549103146 scopus 로고    scopus 로고
    • Inhibition of neuropilin-1 by RNA-interference and its angiostatic potential in the treatment of hepatocellular carcinoma
    • E. Raskopf, A. Vogt, J. Standop, T. Sauerbruch, and V. Schmitz Inhibition of neuropilin-1 by RNA-interference and its angiostatic potential in the treatment of hepatocellular carcinoma Z Gastroenterol 48 2010 21 27
    • (2010) Z Gastroenterol , vol.48 , pp. 21-27
    • Raskopf, E.1    Vogt, A.2    Standop, J.3    Sauerbruch, T.4    Schmitz, V.5
  • 32
    • 0025826837 scopus 로고
    • Time-course development of differentiated hepatocarcinoma and lung metastasis in transgenic mice
    • N. Dubois, M. Bennoun, I. Allemand, T. Molina, G. Grimber, and M. Daudet-Monsac Time-course development of differentiated hepatocarcinoma and lung metastasis in transgenic mice J Hepatol 13 1991 227 239
    • (1991) J Hepatol , vol.13 , pp. 227-239
    • Dubois, N.1    Bennoun, M.2    Allemand, I.3    Molina, T.4    Grimber, G.5    Daudet-Monsac, M.6
  • 33
    • 0037902227 scopus 로고    scopus 로고
    • Tumoral angiogenesis and tissue factor expression during hepatocellular carcinoma progression in a transgenic mouse model
    • DOI 10.1016/S0168-8278(03)00086-2
    • E. Dupuy, P. Hainaud, A. Villemain, E. Bodevin-Phedre, J.P. Brouland, and P. Briand Tumoral angiogenesis and tissue factor expression during hepatocellular carcinoma progression in a transgenic mouse model J Hepatol 38 2003 793 802 (Pubitemid 36613346)
    • (2003) Journal of Hepatology , vol.38 , Issue.6 , pp. 793-802
    • Dupuy, E.1    Hainaud, P.2    Villemain, A.3    Bodevin-Phedre, E.4    Brouland, J.P.5    Briand, P.6    Tobelem, G.7
  • 34
    • 77950960449 scopus 로고    scopus 로고
    • Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease
    • S. Van de Veire, I. Stalmans, F. Heindryckx, H. Oura, A. Tijeras-Raballand, and T. Schmidt Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease Cell 141 2010 178 190
    • (2010) Cell , vol.141 , pp. 178-190
    • Van De Veire, S.1    Stalmans, I.2    Heindryckx, F.3    Oura, H.4    Tijeras-Raballand, A.5    Schmidt, T.6
  • 35
    • 0141844583 scopus 로고    scopus 로고
    • The N-terminal domain of hepatocyte growth factor inhibits the angiogenic behavior of endothelial cells independently from binding to the c-met receptor
    • DOI 10.1074/jbc.M212768200
    • T. Merkulova-Rainon, P. England, S. Ding, C. Demerens, and G. Tobelem The N-terminal domain of hepatocyte growth factor inhibits the angiogenic behavior of endothelial cells independently from binding to the c-met receptor J Biol Chem 278 2003 37400 37408 (Pubitemid 37175259)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.39 , pp. 37400-37408
    • Merkulova-Rainon, T.1    England, P.2    Ding, S.3    Demerens, C.4    Tobelem, G.5
  • 36
    • 0038115223 scopus 로고    scopus 로고
    • HGF receptor up-regulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro
    • S. Ding, T. Merkulova-Rainon, Z.C. Han, and G. Tobelem HGF receptor up-regulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro Blood 101 2003 4816 4822 (Pubitemid 36857740)
    • (2003) Blood , vol.101 , Issue.12 , pp. 4816-4822
    • Ding, S.1    Merkulova-Rainon, T.2    Han, Z.C.3    Tobelem, G.4
  • 37
    • 0037057522 scopus 로고    scopus 로고
    • Neuropilin-1 is differentially expressed in myoepithelial cells and vascular smooth muscle cells in preneoplastic and neoplastic human breast: A possible marker for the progression of breast cancer
    • J.M. Stephenson, S. Banerjee, N.K. Saxena, R. Cherian, and S.K. Banerjee Neuropilin-1 is differentially expressed in myoepithelial cells and vascular smooth muscle cells in preneoplastic and neoplastic human breast: a possible marker for the progression of breast cancer Int J Cancer 101 2002 409 414
    • (2002) Int J Cancer , vol.101 , pp. 409-414
    • Stephenson, J.M.1    Banerjee, S.2    Saxena, N.K.3    Cherian, R.4    Banerjee, S.K.5
  • 40
    • 74549124210 scopus 로고    scopus 로고
    • Development of molecularly targeted therapies in hepatocellular carcinoma: Where do we go now?
    • R.S. Finn Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now? Clin Cancer Res 16 2010 390 397
    • (2010) Clin Cancer Res , vol.16 , pp. 390-397
    • Finn, R.S.1
  • 41
    • 46449091500 scopus 로고    scopus 로고
    • Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma
    • A.B. Siegel, E.I. Cohen, A. Ocean, D. Lehrer, A. Goldenberg, and J.J. Knox Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma J Clin Oncol 26 2008 2992 2998
    • (2008) J Clin Oncol , vol.26 , pp. 2992-2998
    • Siegel, A.B.1    Cohen, E.I.2    Ocean, A.3    Lehrer, D.4    Goldenberg, A.5    Knox, J.J.6
  • 43
    • 70350225520 scopus 로고    scopus 로고
    • Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer
    • L. Xu, D.G. Duda, T.E. di, M. Ancukiewicz, D.C. Chung, and G.Y. Lauwers Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer Cancer Res 69 2009 7905 7910
    • (2009) Cancer Res , vol.69 , pp. 7905-7910
    • Xu, L.1    Duda, D.G.2    Di, T.E.3    Ancukiewicz, M.4    Chung, D.C.5    Lauwers, G.Y.6
  • 45
    • 35948964766 scopus 로고    scopus 로고
    • Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1
    • DOI 10.1158/0008-5472.CAN-07-3256
    • A. Matsushita, T. Gotze, and M. Korc Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1 Cancer Res 67 2007 10309 10316 (Pubitemid 350070805)
    • (2007) Cancer Research , vol.67 , Issue.21 , pp. 10309-10316
    • Matsushita, A.1    Gotze, T.2    Korc, M.3
  • 46
    • 76749152925 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells
    • S. Zhang, H.E. Zhau, A.O. Osunkoya, S. Iqbal, X. Yang, and S. Fan Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells Mol Cancer 9 2010 9
    • (2010) Mol Cancer , vol.9 , pp. 9
    • Zhang, S.1    Zhau, H.E.2    Osunkoya, A.O.3    Iqbal, S.4    Yang, X.5    Fan, S.6
  • 47
    • 42449148407 scopus 로고    scopus 로고
    • Neuropilins: Structure, function and role in disease
    • DOI 10.1042/BJ20071639
    • C. Pellet-Many, P. Frankel, H. Jia, and I. Zachary Neuropilins: structure, function and role in disease Biochem J 411 2008 211 226 (Pubitemid 351580173)
    • (2008) Biochemical Journal , vol.411 , Issue.2 , pp. 211-226
    • Pellet-Many, C.1    Frankel, P.2    Jia, H.3    Zachary, I.4
  • 48
    • 0034756449 scopus 로고    scopus 로고
    • Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins
    • DOI 10.1016/S0925-4773(01)00518-4, PII S0925477301005184
    • Y. Herzog, C. Kalcheim, N. Kahane, R. Reshef, and G. Neufeld Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins Mech Dev 109 2001 115 119 (Pubitemid 33035924)
    • (2001) Mechanisms of Development , vol.109 , Issue.1 , pp. 115-119
    • Herzog, Y.1    Kalcheim, C.2    Kahane, N.3    Reshef, R.4    Neufeld, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.