-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: Therapeutic implications. N Engl J Med. 1971;285:1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
78649932949
-
Biology of anti-angiogenic therapy-induced thrombotic microangiopathy
-
Eremina V, Quaggin SE. Biology of anti-angiogenic therapy-induced thrombotic microangiopathy. Semin Nephrol. 2010;30:582-90.
-
(2010)
Semin Nephrol
, vol.30
, pp. 582-590
-
-
Eremina, V.1
Quaggin, S.E.2
-
3
-
-
33845313345
-
The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; A review
-
DOI 10.1016/j.ejca.2006.09.015, PII S0959804906008483
-
Eskens FA, Verweij J. The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review. Eur J Cancer. 2006;42:3127-39. (Pubitemid 44869016)
-
(2006)
European Journal of Cancer
, vol.42
, Issue.18
, pp. 3127-3139
-
-
Eskens, F.A.L.M.1
Verweij, J.2
-
4
-
-
0037699954
-
The biology of VEGF and its receptors
-
DOI 10.1038/nm0603-669
-
Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med. 2003;9:669-76. (Pubitemid 36749215)
-
(2003)
Nature Medicine
, vol.9
, Issue.6
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.-P.2
LeCouter, J.3
-
5
-
-
73649105168
-
Cardiovascular and renal toxicity during angiogenesis inhibition: Clinical and mechanistic aspects
-
Excellent overview of the vascular effects and toxicities of anti-VEGF agents
-
• Kappers MH, van Esch JH, Sleijfer S, Danser AH, van den Meiracker AH. Cardiovascular and renal toxicity during angiogenesis inhibition: Clinical and mechanistic aspects. J Hypertens. 2009;27:2297-309. Excellent overview of the vascular effects and toxicities of anti-VEGF agents.
-
(2009)
J Hypertens.
, vol.27
, pp. 2297-2309
-
-
Kappers, M.H.1
Van Esch, J.H.2
Sleijfer, S.3
Danser, A.H.4
Van Den Meiracker, A.H.5
-
6
-
-
3543131382
-
A naturally occurring soluble form of vascular endothelial growth factor receptor 2 detected in mouse and human plasma
-
Ebos JM, Bocci G, Man S, et al. A naturally occurring soluble form of vascular endothelial growth factor receptor 2 detected in mouse and human plasma. Mol Cancer Res. 2004;2:315-26. (Pubitemid 39025294)
-
(2004)
Molecular Cancer Research
, vol.2
, Issue.6
, pp. 315-326
-
-
Ebos, J.M.L.1
Bocci, G.2
Man, S.3
Thorpe, P.E.4
Hicklin, D.J.5
Zhou, D.6
Jia, X.7
Kerbel, R.S.8
-
7
-
-
0036381363
-
VEGF is an essential molecule for glomerular structuring
-
Kitamoto Y, Tokunaga H, Miyamoto K, Tomita K. VEGF is an essential molecule for glomerular structuring. Nephrol Dial Transplant. 2002;17 Suppl 9:25-7.
-
(2002)
Nephrol Dial Transplant.
, vol.17
, Issue.SUPPL. 9
, pp. 25-27
-
-
Kitamoto, Y.1
Tokunaga, H.2
Miyamoto, K.3
Tomita, K.4
-
8
-
-
33846638744
-
Risks of Proteinuria and Hypertension With Bevacizumab, an Antibody Against Vascular Endothelial Growth Factor: Systematic Review and Meta-Analysis
-
DOI 10.1053/j.ajkd.2006.11.039, PII S0272638606018336
-
Zhu X, Wu S, Dahut WL, Parikh CR. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis. Am J Kidney Dis. 2007;49:186-93. (Pubitemid 46178407)
-
(2007)
American Journal of Kidney Diseases
, vol.49
, Issue.2
, pp. 186-193
-
-
Zhu, X.1
Wu, S.2
Dahut, W.L.3
Parikh, C.R.4
-
10
-
-
34249294557
-
Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition
-
DOI 10.1038/nrc2152, PII NRC2152
-
Verheul HM, Pinedo HM. Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Nat Rev Cancer. 2007;7:475-85. (Pubitemid 46809172)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.6
, pp. 475-485
-
-
Verheul, H.M.W.1
Pinedo, H.M.2
-
11
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
DOI 10.1056/NEJMoa032691
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-42. (Pubitemid 38702844)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
12
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
DOI 10.1200/JCO.2005.05.098
-
Miller KD, Chap LI, Holmes FA, et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol. 2005;23:792-9. (Pubitemid 46224178)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
Cobleigh, M.A.4
Marcom, P.K.5
Fehrenbacher, L.6
Dickler, M.7
Overmoyer, B.A.8
Reimann, J.D.9
Sing, A.P.10
Langmuir, V.11
Rugo, H.S.12
-
13
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
DOI 10.1056/NEJMoa021491
-
Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med. 2003;349:427-34. (Pubitemid 36910021)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
14
-
-
80052597321
-
Mechanisms of antiangiogenic-induced arterial hypertension
-
Mourad JJ, Levy BI. Mechanisms of antiangiogenic-induced arterial hypertension. Curr Hypertens Rep. 2011;13:289-93.
-
(2011)
Curr Hypertens Rep
, vol.13
, pp. 289-293
-
-
Mourad, J.J.1
Levy, B.I.2
-
15
-
-
70350002279
-
Adverse effects of anticancer agents that target the VEGF pathway
-
Chen HX, Cleck JN. Adverse effects of anticancer agents that target the VEGF pathway. Nat Rev Clin Oncol. 2009;6:465-77.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 465-477
-
-
Chen, H.X.1
Cleck, J.N.2
-
16
-
-
34547681379
-
Phase I clinical study of AZD2171, an oral vascular endothelial growth factor signaling inhibitor, in patients with advanced solid tumors
-
DOI 10.1200/JCO.2006.07.2066
-
Drevs J, Siegert P, Medinger M, et al. Phase I clinical study of AZD2171, an oral vascular endothelial growth factor signaling inhibitor, in patients with advanced solid tumors. J Clin Oncol. 2007;25:3045-54. (Pubitemid 47218051)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.21
, pp. 3045-3054
-
-
Drevs, J.1
Siegert, P.2
Medinger, M.3
Mross, K.4
Strecker, R.5
Zirrgiebel, U.6
Harder, J.7
Blum, H.8
Robertson, J.9
Jurgensmeier, J.M.10
Puchalski, T.A.11
Young, H.12
Saunders, O.13
Unger, C.14
-
17
-
-
67650337802
-
Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043
-
Sleijfer S, Ray-Coquard I, Papai Z, et al. Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). J Clin Oncol. 2009;27:3126-32.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 3126-3132
-
-
Sleijfer, S.1
Ray-Coquard, I.2
Papai, Z.3
-
18
-
-
0034176245
-
Common toxicity criteria: Version 2.0. An improved reference for grading the acute effects of cancer treatment: Impact on radiotherapy
-
DOI 10.1016/S0360-3016(99)00559-3, PII S0360301699005593
-
Trotti A, Byhardt R, Stetz JA, et al. Common toxicity criteria: Version 2.0. An improved reference for grading the acute effects of cancer treatment: Impact on radiotherapy. Int J Radiat Oncol Biol Phys. 2000;47:13-47. (Pubitemid 30179675)
-
(2000)
International Journal of Radiation Oncology Biology Physics
, vol.47
, Issue.1
, pp. 13-47
-
-
Trotti, A.1
Byhardt, R.2
Stetz, J.3
Gwede, C.4
Corn, B.5
Fu, K.6
Gunderson, L.7
McCormick, B.8
Morris, M.9
Rich, T.10
Shipley, W.11
Curran, W.12
-
19
-
-
0037242152
-
Modifications structurelles et fonctionnelles de la microcirculation dans l'hypertension: Influence du traitement pharmacologique
-
DOI 10.2165/00003495-200363991-00003
-
Agabiti-Rosei E. Structural and functional changes of the microcirculation in hypertension: Influence of pharmacological therapy. Drugs. 2003;63(Spec No 1):19-29. (Pubitemid 36384615)
-
(2003)
Drugs
, vol.63
, Issue.SPEC. ISS. 1
, pp. 19-29
-
-
Agabiti-Rosei, E.1
-
20
-
-
10744228140
-
CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment
-
DOI 10.1016/S1053-4296(03)00031-6
-
Trotti A, Colevas AD, Setser A, et al. CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol. 2003;13:176-81. (Pubitemid 36962641)
-
(2003)
Seminars in Radiation Oncology
, vol.13
, Issue.3
, pp. 176-181
-
-
Trotti, A.1
Colevas, A.D.2
Setser, A.3
Rusch, V.4
Jaques, D.5
Budach, V.6
Langer, C.7
Murphy, B.8
Cumberlin, R.9
Coleman, C.N.10
Rubin, P.11
-
21
-
-
0347423198
-
Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
-
DOI 10.1161/01.HYP.0000107251.49515.c2
-
Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension. 2003;42:1206-52. (Pubitemid 37553153)
-
(2003)
Hypertension
, vol.42
, Issue.6
, pp. 1206-1252
-
-
Chobanian, A.V.1
Bakris, G.L.2
Black, H.R.3
Cushman, W.C.4
Green, L.A.5
Izzo Jr., J.L.6
Jones, D.W.7
Materson, B.J.8
Oparil, S.9
Wright Jr., J.T.10
Roccella, E.J.11
-
22
-
-
38549085315
-
Incidence and risk of hypertension with sorafenib in patients with cancer: A systematic review and meta-analysis
-
Wu S, Chen JJ, Kudelka A, Lu J, Zhu X. Incidence and risk of hypertension with sorafenib in patients with cancer: A systematic review and meta-analysis. Lancet Oncol. 2008;9:117-23.
-
(2008)
Lancet Oncol.
, vol.9
, pp. 117-123
-
-
Wu, S.1
Chen, J.J.2
Kudelka, A.3
Lu, J.4
Zhu, X.5
-
23
-
-
63049093371
-
Phase I trial of bevacizumab plus escalated doses of sunitinib in patients with metastatic renal cell carcinoma
-
Feldman DR, Baum MS, Ginsberg MS, et al. Phase I trial of bevacizumab plus escalated doses of sunitinib in patients with metastatic renal cell carcinoma. J Clin Oncol. 2009;27:1432-9.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 1432-1439
-
-
Feldman, D.R.1
Baum, M.S.2
Ginsberg, M.S.3
-
24
-
-
49249113484
-
Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity
-
Azad NS, Posadas EM, Kwitkowski VE, et al. Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncol. 2008;26:3709-14.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3709-3714
-
-
Azad, N.S.1
Posadas, E.M.2
Kwitkowski, V.E.3
-
25
-
-
77952038495
-
Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors
-
Maitland ML, Bakris GL, Black HR, et al. Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors. J Natl Cancer Inst. 2010;102:596-604.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 596-604
-
-
Maitland, M.L.1
Bakris, G.L.2
Black, H.R.3
-
26
-
-
0031943236
-
VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells
-
Hood JD, Meininger CJ, Ziche M, Granger HJ. VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am J Physiol. 1998;274:H1054-8.
-
(1998)
Am J Physiol.
, vol.274
-
-
Hood, J.D.1
Meininger, C.J.2
Ziche, M.3
Granger, H.J.4
-
27
-
-
0031471950
-
Vascular endothelial growth factor/vascular permeability factor produces nitric oxide-dependent hypotension: Evidence for a maintenance role in quiescent adult endothelium
-
Horowitz JR, Rivard A, van der Zee R, et al. Vascular endothelial growth factor/vascular permeability factor produces nitric oxidedependent hypotension. Evidence for a maintenance role in quiescent adult endothelium. Arterioscler Thromb Vasc Biol. 1997;17:2793-800. (Pubitemid 28016023)
-
(1997)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.17
, Issue.11
, pp. 2793-2800
-
-
Horowitz, J.R.1
Rivard, A.2
Van Der Zee, R.3
Hariawala, M.4
Sheriff, D.D.5
Esakof, D.D.6
Muqtada Chaudhry, G.7
Symes, J.F.8
Isner, J.M.9
-
28
-
-
0348049834
-
VEGF signalling: Integration and multi-tasking in endothelial cell biology
-
Zachary I. VEGF signalling: Integration and multi-tasking in endothelial cell biology. Biochem Soc Trans. 2003;31:1171-7. (Pubitemid 38030933)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.6
, pp. 1171-1177
-
-
Zachary, I.1
-
29
-
-
0036899189
-
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: Role of PI3K, PKC and PLC pathways
-
DOI 10.1038/sj.bjp.0704956
-
Gelinas DS, Bernatchez PN, Rollin S, Bazan NG, Sirois MG. Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: Role of PI3K, PKC and PLC pathways. Br J Pharmacol. 2002;137:1021-30 (Pubitemid 35440742)
-
(2002)
British Journal of Pharmacology
, vol.137
, Issue.7
, pp. 1021-1030
-
-
Gelinas, D.S.1
Bernatchez, P.N.2
Rollin, S.3
Bazan, N.G.4
Sirois, M.G.5
-
30
-
-
0036281152
-
KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF
-
DOI 10.1161/01.HYP.0000018588.56950.7A
-
Li B, Ogasawara AK, Yang R, et al. KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF. Hypertension. 2002;39:1095-100. (Pubitemid 34620130)
-
(2002)
Hypertension
, vol.39
, Issue.6
, pp. 1095-1100
-
-
Li, B.1
Ogasawara, A.K.2
Yang, R.3
Wei, W.4
He, G.-W.5
Zioncheck, T.F.6
Bunting, S.7
De Vos, A.M.8
Jin, H.9
-
31
-
-
0037453099
-
The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis
-
DOI 10.1161/01.CIR.0000061911.47710.8A
-
Henry TD, Annex BH, McKendall GR, et al. The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation. 2003;107:1359-65. (Pubitemid 36350732)
-
(2003)
Circulation
, vol.107
, Issue.10
, pp. 1359-1365
-
-
Henry, T.D.1
Annex, B.H.2
McKendall, G.R.3
Azrin, M.A.4
Lopez, J.J.5
Giordano, F.J.6
Shah, P.K.7
Willerson, J.T.8
Benza, R.L.9
Berman, D.S.10
Gibson, C.M.11
Bajamonde, A.12
Rundle, A.C.13
Fine, J.14
McCluskey, E.R.15
-
32
-
-
0033108016
-
Role of nitric oxide in the control of renal function and salt sensitivity
-
Zou AP, Cowley Jr AW. Role of nitric oxide in the control of renal function and salt sensitivity. Curr Hypertens Rep. 1999;1:178-86.
-
(1999)
Curr Hypertens Rep
, vol.1
, pp. 178-186
-
-
Zou, A.P.1
Cowley Jr., A.W.2
-
33
-
-
43049085201
-
Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation
-
DOI 10.1093/annonc/mdm550
-
Mourad JJ, des Guetz G, Debbabi H, Levy BI. Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol. 2008;19:927-34. (Pubitemid 351627309)
-
(2008)
Annals of Oncology
, vol.19
, Issue.5
, pp. 927-934
-
-
Mourad, J.-J.1
Des Guetz, G.2
Debbabi, H.3
Levy, B.I.4
-
34
-
-
33751076238
-
Hypertension: A disease of the microcirculation?
-
DOI 10.1161/01.HYP.0000249510.20326.72, PII 0000426820061200000003
-
Feihl F, Liaudet L, Waeber B, Levy BI. Hypertension: A disease of the microcirculation? Hypertension. 2006;48:1012-7. (Pubitemid 44772698)
-
(2006)
Hypertension
, vol.48
, Issue.6
, pp. 1012-1017
-
-
Feihl, F.1
Liaudet, L.2
Waeber, B.3
Levy, B.I.4
-
35
-
-
0035988521
-
Inhibition of NO biosynthesis, but not elevated blood pressure, reduces angiogenesis in rat models of secondary hypertension
-
DOI 10.1080/08037050211256
-
Kiefer FN, Misteli H, Kalak N, et al. Inhibition of NO biosynthesis, but not elevated blood pressure, reduces angiogenesis in rat models of secondary hypertension. Blood Press. 2002;11:116-24. (Pubitemid 34537522)
-
(2002)
Blood Pressure
, vol.11
, Issue.2
, pp. 116-124
-
-
Kiefer, F.N.1
Misteli, H.2
Kalak, N.3
Tschudin, K.4
Fingerle, J.5
Van Der Kooij, M.6
Stumm, M.7
Sumanovski, L.T.8
Sieber, C.C.9
Battegay, E.J.10
-
36
-
-
50349101200
-
Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor
-
Steeghs N, Gelderblom H, Roodt JO, et al. Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor. Clin Cancer Res. 2008;14:3470-6.
-
(2008)
Clin Cancer Res.
, vol.14
, pp. 3470-3476
-
-
Steeghs, N.1
Gelderblom, H.2
Roodt, J.O.3
-
37
-
-
33645449812
-
Mechanisms of hypertension associated with BAY 43-9006
-
DOI 10.1200/JCO.2005.02.0503
-
Veronese ML, Mosenkis A, Flaherty KT, et al. Mechanisms of hypertension associated with BAY 43-9006. J Clin Oncol. 2006;24:1363-9. (Pubitemid 46621999)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.9
, pp. 1363-1369
-
-
Veronese, M.L.1
Mosenkis, A.2
Flaherty, K.T.3
Gallagher, M.4
Stevenson, J.P.5
Townsend, R.R.6
O'Dwyer, P.J.7
-
39
-
-
0027245639
-
Loss of mitotic activity and the expression of vimentin in glomerular epithelial cells of developing human kidneys
-
Nagata M, Yamaguchi Y, Ito K. Loss of mitotic activity and the expression of vimentin in glomerular epithelial cells of developing human kidneys. Anat Embryol (Berl). 1993;187:275-9. (Pubitemid 23128035)
-
(1993)
Anatomy and Embryology
, vol.187
, Issue.3
, pp. 275-279
-
-
Nagata, M.1
Yamaguchi, Y.2
Ito, K.3
-
40
-
-
0033958396
-
The glomerular slit diaphragm is a modified adherens junction
-
Reiser J, Kriz W, Kretzler M, Mundel P. The glomerular slit diaphragm is a modified adherens junction. J Am Soc Nephrol. 2000;11:1-8. (Pubitemid 30020420)
-
(2000)
Journal of the American Society of Nephrology
, vol.11
, Issue.1
, pp. 1-8
-
-
Reiser, J.1
Kriz, W.2
Kretzler, M.3
Mundel, P.4
-
41
-
-
0032015551
-
Positionally cloned gene for a novel glomerular protein - Nephrin - Is mutated in congenital nephrotic syndrome
-
Kestila M, Lenkkeri U, Mannikko M, et al. Positionally cloned gene for a novel glomerular protein -nephrin -is mutated in congenital nephrotic syndrome. Mol Cell. 1998;1:575-82. (Pubitemid 128374693)
-
(1998)
Molecular Cell
, vol.1
, Issue.4
, pp. 575-582
-
-
Kestila, M.1
Lenkkeri, U.2
Mannikko, M.3
Lamerdin, J.4
McCready, P.5
Putaala, H.6
Ruotsalainen, V.7
Morita, T.8
Nissinen, M.9
Herva, R.10
Kashtan, C.E.11
Peltonen, L.12
Holmberg, C.13
Olsen, A.14
Tryggvason, K.15
-
42
-
-
0034948819
-
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
-
DOI 10.1128/MCB.21.14.4829-4836.2001
-
Donoviel DB, Freed DD, Vogel H, et al. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol. 2001;21:4829-36. (Pubitemid 32588261)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.14
, pp. 4829-4836
-
-
Donoviel, D.B.1
Freed, D.D.2
Vogel, H.3
Potter, D.G.4
Hawkins, E.5
Barrish, J.P.6
Mathur, B.N.7
Turner, C.A.8
Geske, R.9
Montgomery, C.A.10
Starbuck, M.11
Brandt, M.12
Gupta, A.13
Ramirez-Solis, R.14
Zambrowicz, B.P.15
Powell, D.R.16
-
43
-
-
0035210324
-
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
-
DOI 10.1172/JCI200112849
-
Schwarz K, Simons M, Reiser J, et al. Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J Clin Invest. 2001;108:1621-9. (Pubitemid 33144872)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.11
, pp. 1621-1629
-
-
Schwarz, K.1
Simons, M.2
Reiser, J.3
Saleem, M.A.4
Faul, C.5
Kriz, W.6
Shaw, A.S.7
Holzman, L.B.8
Mundel, P.9
-
44
-
-
0033536599
-
Congenital nephrotic syndrome in mice lacking CD2-associated protein
-
DOI 10.1126/science.286.5438.312
-
Shih NY, Li J, Karpitskii V, et al. Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science. 1999;286:312-5. (Pubitemid 29484698)
-
(1999)
Science
, vol.286
, Issue.5438
, pp. 312-315
-
-
Shih, N.-Y.1
Li, J.2
Karpitskii, V.3
Nguyen, A.4
Dustin, M.L.5
Kanagawa, O.6
Miner, J.H.7
Shaw, A.S.8
-
45
-
-
0032929050
-
The dysregulated podocyte phenotype: A novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV- associated nephropathy
-
Barisoni L, Kriz W, Mundel P, D'Agati V. The dysregulated podocyte phenotype: A novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIVassociated nephropathy. J Am Soc Nephrol. 1999;10:51-61. (Pubitemid 29034942)
-
(1999)
Journal of the American Society of Nephrology
, vol.10
, Issue.1
, pp. 51-61
-
-
Barisoni, L.1
Kriz, W.2
Mundel, P.3
D'Agati, V.4
-
46
-
-
34047126908
-
Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia
-
DOI 10.1093/ndt/gfl711
-
Garovic VD, Wagner SJ, Petrovic LM, et al. Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. Nephrol Dial Transplant. 2007;22:1136-43. (Pubitemid 46523429)
-
(2007)
Nephrology Dialysis Transplantation
, vol.22
, Issue.4
, pp. 1136-1143
-
-
Garovic, V.D.1
Wagner, S.J.2
Petrovic, L.M.3
Gray, C.E.4
Hall, P.5
Sugimoto, H.6
Kalluri, R.7
Grande, J.P.8
-
47
-
-
40849130173
-
VEGF inhibition and renal thrombotic microangiopathy
-
DOI 10.1056/NEJMoa0707330
-
Eremina V, Jefferson JA, Kowalewska J, et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med. 2008;358:1129-36. (Pubitemid 351398487)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.11
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
Hochster, H.4
Haas, M.5
Weisstuch, J.6
Richardson, C.7
Kopp, J.B.8
Kabir, M.G.9
Backx, P.H.10
Gerber, H.-P.11
Ferrara, N.12
Barisoni, L.13
Alpers, C.E.14
Quaggin, S.E.15
-
48
-
-
39649122843
-
A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib
-
DOI 10.1093/jnci/djm311
-
Patel TV, Morgan JA, Demetri GD, et al. A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib. J Natl Cancer Inst. 2008;100:282-4. (Pubitemid 351480534)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.4
, pp. 282-284
-
-
Patel, T.V.1
Morgan, J.A.2
Demetri, G.D.3
George, S.4
Maki, R.G.5
Quigley, M.6
Humphreys, B.D.7
-
49
-
-
33846365410
-
An open label phase I dose escalation study of KRN951, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 1 in a 4 week on, 2 week off schedule in patients with advanced solid tumors (Abstract
-
Eskens FAP, van Doorn A. An open label phase I dose escalation study of KRN951, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 1 in a 4 week on, 2 week off schedule in patients with advanced solid tumors (Abstract). J Clin Oncol. 2006;24:2034.
-
(2006)
J Clin Oncol.
, vol.24
, pp. 2034
-
-
Eskens, F.A.P.1
Van Doorn, A.2
-
50
-
-
72449132908
-
VEGF signalling inhibition-induced proteinuria: Mechanisms, significance and management
-
Izzedine H, Massard C, Spano JP, et al. VEGF signalling inhibition-induced proteinuria: Mechanisms, significance and management. Eur J Cancer. 2010;46:439-48.
-
(2010)
Eur J Cancer
, vol.46
, pp. 439-448
-
-
Izzedine, H.1
Massard, C.2
Spano, J.P.3
-
51
-
-
33846263493
-
Chronic lymphocytic leukemia and cryoglobulinemic glomerulonephritis
-
DOI 10.1038/sj.ki.5001891, PII 5001891
-
Nasr SH, Snyder RW, Bhagat G, Markowitz GS. Chronic lymphocytic leukemia and cryoglobulinemic glomerulonephritis. Kidney Int. 2007;71:93. (Pubitemid 46094679)
-
(2007)
Kidney International
, vol.71
, Issue.2
, pp. 93
-
-
Nasr, S.H.1
Snyder, R.W.2
Bhagat, G.3
Markowitz, G.S.4
-
52
-
-
37549036619
-
Allergic interstitial nephritis possibly related to sunitinib use
-
Khurana A. Allergic interstitial nephritis possibly related to sunitinib use. Am J Geriatr Pharmacother. 2007;5:341-4.
-
(2007)
Am J Geriatr Pharmacother
, vol.5
, pp. 341-344
-
-
Khurana, A.1
-
53
-
-
34547830298
-
Interstitial nephritis in a patient taking sorafenib [8]
-
DOI 10.1093/ndt/gfm199
-
Izzedine H, Brocheriou I, Rixe O, Deray G. Interstitial nephritis in a patient taking sorafenib. Nephrol Dial Transplant. 2007;22:2411. (Pubitemid 47244737)
-
(2007)
Nephrology Dialysis Transplantation
, vol.22
, Issue.8
, pp. 2411
-
-
Izzedine, H.1
Brocheriou, I.2
Rixe, O.3
Deray, G.4
-
54
-
-
56549115248
-
Glomerular disease related to anti-VEGF therapy
-
Stokes MB, Erazo MC, D'Agati VD. Glomerular disease related to anti-VEGF therapy. Kidney Int. 2008;74:1487-91.
-
(2008)
Kidney Int
, vol.74
, pp. 1487-1491
-
-
Stokes, M.B.1
Erazo, M.C.2
D'Agati, V.D.3
-
55
-
-
79955624389
-
Crescentic glomerulonephritis associated with vascular endothelial growth factor (VEGF) inhibitor and bisphosphonate administration
-
Stylianou K, Lioudaki E, Papadimitraki E, et al. Crescentic glomerulonephritis associated with vascular endothelial growth factor (VEGF) inhibitor and bisphosphonate administration. Nephrol Dial Transplant. 2011;26:1742-5.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 1742-1745
-
-
Stylianou, K.1
Lioudaki, E.2
Papadimitraki, E.3
-
56
-
-
77649222696
-
Inhibition of tyrosine kinases by sunitinib associated with focal segmental glomerulosclerosis lesion in addition to thrombotic microangiopathy
-
Costero O, Picazo ML, Zamora P, et al. Inhibition of tyrosine kinases by sunitinib associated with focal segmental glomerulosclerosis lesion in addition to thrombotic microangiopathy. Nephrol Dial Transplant. 2010;25:1001-3.
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 1001-1003
-
-
Costero, O.1
Picazo, M.L.2
Zamora, P.3
-
57
-
-
58449096748
-
Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib
-
Bollee G, Patey N, Cazajous G, et al. Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib. Nephrol Dial Transplant. 2009;24:682-5.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 682-685
-
-
Bollee, G.1
Patey, N.2
Cazajous, G.3
-
59
-
-
79954598744
-
Systemic and kidney toxicity of intraocular administration of vascular endothelial growth factor inhibitors
-
Pelle G, Shweke N, Duong Van Huyen JP, et al. Systemic and kidney toxicity of intraocular administration of vascular endothelial growth factor inhibitors. Am J Kidney Dis. 2011;57:756-9.
-
(2011)
Am J Kidney Dis.
, vol.57
, pp. 756-759
-
-
Pelle, G.1
Shweke, N.2
Duong Van Huyen, J.P.3
-
60
-
-
21344446946
-
Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria
-
DOI 10.1681/ASN.2005020159
-
Yu D, Petermann A, Kunter U, et al. Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria. J Am Soc Nephrol. 2005;16:1733-41. (Pubitemid 41716479)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.6
, pp. 1733-1741
-
-
Yu, D.1
Petermann, A.2
Kunter, U.3
Rong, S.4
Shankland, S.J.5
Floege, J.6
-
61
-
-
77955964458
-
Renal side effects of VEGF-blocking therapy
-
First article reporting the presence of podocyturia in patients with proteinuria treated with anti-VEGF therapy
-
•• Müller-Deile J, Bröcker V, Grünwald V, et al. Renal side effects of VEGF-blocking therapy. NDT Plus. 2010;3:172-5. First article reporting the presence of podocyturia in patients with proteinuria treated with anti-VEGF therapy.
-
(2010)
NDT Plus.
, vol.3
, pp. 172-175
-
-
Müller-Deile, J.1
Bröcker, V.2
Grünwald, V.3
-
63
-
-
77953354537
-
Reversibility of capillary density after discontinuation of bevacizumab treatment
-
First study showing that decreased capillary density as a result of bevacizumab is reversible and that capillary density may represent a marker of treatment efficacy
-
•• Steeghs N, Rabelink TJ, op 't Roodt J, et al. Reversibility of capillary density after discontinuation of bevacizumab treatment. Ann Oncol. 2010;21:1100-5. First study showing that decreased capillary density as a result of bevacizumab is reversible and that capillary density may represent a marker of treatment efficacy.
-
(2010)
Ann Oncol.
, vol.21
, pp. 1100-1105
-
-
Steeghs, N.1
Rabelink, T.J.2
Op't Roodt, J.3
-
64
-
-
65549119311
-
Arterial hypertension and clinical benefit of sunitinib, sorafenib and bevacizumab in first and second-line treatment of metastatic renal cell cancer
-
author reply 7
-
Ravaud A, Sire M. Arterial hypertension and clinical benefit of sunitinib, sorafenib and bevacizumab in first and second-line treatment of metastatic renal cell cancer. Ann Oncol. 2009;20:966-7. author reply 7.
-
(2009)
Ann Oncol.
, vol.20
, pp. 966-967
-
-
Ravaud, A.1
Sire, M.2
-
65
-
-
34447343347
-
Hypertension as a predictive factor of Sunitinib activity [1]
-
DOI 10.1093/annonc/mdm184
-
Rixe O, Billemont B, Izzedine H. Hypertension as a predictive factor of Sunitinib activity. Ann Oncol. 2007;18:1117. (Pubitemid 47050505)
-
(2007)
Annals of Oncology
, vol.18
, Issue.6
, pp. 1117
-
-
Rixe, O.1
Billemont, B.2
Izzedine, H.3
-
66
-
-
60549113344
-
Blood pressure as a potential biomarker of the efficacy angiogenesis inhibitor
-
Levy BI. Blood pressure as a potential biomarker of the efficacy angiogenesis inhibitor. Ann Oncol. 2009;20:200-3.
-
(2009)
Ann Oncol
, vol.20
, pp. 200-203
-
-
Levy, B.I.1
-
67
-
-
60549095633
-
Hypertension and clinical benefit of bevacizumab in the treatment of advanced renal cell carcinoma
-
Bono P, Elfving H, Utriainen T, et al. Hypertension and clinical benefit of bevacizumab in the treatment of advanced renal cell carcinoma. Ann Oncol. 2009;20:393-4.
-
(2009)
Ann Oncol.
, vol.20
, pp. 393-394
-
-
Bono, P.1
Elfving, H.2
Utriainen, T.3
-
68
-
-
65549149179
-
Hypertension as a surrogate marker for the activity of anti-VEGF agents
-
Mir O, Ropert S, Alexandre J, Goldwasser F. Hypertension as a surrogate marker for the activity of anti-VEGF agents. Ann Oncol. 2009;20:967-70.
-
(2009)
Ann Oncol
, vol.20
, pp. 967-970
-
-
Mir, O.1
Ropert, S.2
Alexandre, J.3
Goldwasser, F.4
-
69
-
-
79951673901
-
Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy
-
Study that most clearly demonstrates an association between hypertension and overall survival in patients treated with bevacizumab
-
• Osterlund P, Soveri LM, Isoniemi H, et al. Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy. Br J Cancer. 2011;104:599-604. Study that most clearly demonstrates an association between hypertension and overall survival in patients treated with bevacizumab.
-
(2011)
Br J Cancer.
, vol.104
, pp. 599-604
-
-
Osterlund, P.1
Soveri, L.M.2
Isoniemi, H.3
-
70
-
-
84863338437
-
Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib
-
Kim JJ, Vaziri SAJ, Rini BI, et al. Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib. Cancer. 2012:118(7):1946-54.
-
(2012)
Cancer.
, vol.118
, Issue.7
, pp. 1946-1954
-
-
Kim, J.J.1
Vaziri, S.A.J.2
Rini, B.I.3
-
71
-
-
81255160848
-
Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: A multicentre, observational, prospective study
-
Garcia-Donas J, Esteban E, Leandro-Garcia LJ, et al. Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: A multicentre, observational, prospective study. Lancet Oncol. 2011;12:1143-50.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1143-1150
-
-
Garcia-Donas, J.1
Esteban, E.2
Leandro-Garcia, L.J.3
-
72
-
-
74949128620
-
Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: Results from a phase II randomized, factorial, double-blind study of Cediranib in patients with advanced solid tumors
-
Langenberg MH, van Herpen CM, De Bono J, et al. Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: Results from a phase II randomized, factorial, double-blind study of Cediranib in patients with advanced solid tumors. J Clin Oncol. 2009;27:6152-9.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6152-6159
-
-
Langenberg, M.H.1
Van Herpen, C.M.2
De Bono, J.3
-
73
-
-
23244467359
-
Nifedipine-induces vascular endothelial growth factor secretion from coronary smooth muscle cells promotes endothelial-containing receptor/fetal liver kinase-1/NO pathway
-
DOI 10.1291/hypres.28.147
-
Miura S, Fujino M, Matsuo Y, Tanigawa H, Saku K. Nifedipineinduced vascular endothelial growth factor secretion from coronary smooth muscle cells promotes endothelial tube formation via the kinase insert domain-containing receptor/fetal liver kinase-1/ NO pathway. Hypertens Res. 2005;28:147-53. (Pubitemid 40663066)
-
(2005)
Hypertension Research
, vol.28
, Issue.2
, pp. 147-153
-
-
Miura, S.-I.1
Fujino, M.2
Matsuo, Y.3
Tanigawa, H.4
Saku, K.5
-
74
-
-
33748630761
-
Potential deployment of angiotensin I converting enzyme inhibitors and of angiotensin II type 1 and type 2 receptor blockers in cancer chemotherapy
-
Molteni A, Heffelfinger S, Moulder JE, Uhal B, Castellani WJ. Potential deployment of angiotensin I converting enzyme inhibitors and of angiotensin II type 1 and type 2 receptor blockers in cancer chemotherapy. Anticancer Agents Med Chem. 2006;6:451-60. (Pubitemid 44377779)
-
(2006)
Anti-Cancer Agents in Medicinal Chemistry
, vol.6
, Issue.5
, pp. 451-460
-
-
Molteni, A.1
Heffelfinger, S.2
Moulder, J.E.3
Uhal, B.4
Castellani, W.J.5
-
75
-
-
65549122619
-
Management of hypertension in angiogenesis inhibitor-treated patients
-
Izzedine H, Ederhy S, Goldwasser F, et al. Management of hypertension in angiogenesis inhibitor-treated patients. Ann Oncol. 2009;20:807-15.
-
(2009)
Ann Oncol
, vol.20
, pp. 807-815
-
-
Izzedine, H.1
Ederhy, S.2
Goldwasser, F.3
-
76
-
-
0036020933
-
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: Differing effects of anti-proteinuric therapies
-
Kelly DJ, Aaltonen P, Cox AJ, et al. Expression of the slitdiaphragm protein, nephrin, in experimental diabetic nephropathy: Differing effects of anti-proteinuric therapies. Nephrol Dial Transplant. 2002;17:1327-32. (Pubitemid 34812081)
-
(2002)
Nephrology Dialysis Transplantation
, vol.17
, Issue.7
, pp. 1327-1332
-
-
Kelly, D.J.1
Aaltonen, P.2
Cox, A.J.3
Rumble, J.R.4
Langham, R.5
Panagiotopoulos, S.6
Jerums, G.7
Holthofer, H.8
Gilbert, R.E.9
-
77
-
-
34447345394
-
Treatment of arterial hypertension (AHT) associated with angiogenesis inhibitors [5]
-
DOI 10.1093/annonc/mdm205
-
Dirix LY, Maes H, Sweldens C. Treatment of arterial hypertension (AHT) associated with angiogenesis inhibitors. Ann Oncol. 2007;18:1121-2. (Pubitemid 47050509)
-
(2007)
Annals of Oncology
, vol.18
, Issue.6
, pp. 1121-1122
-
-
Dirix, K.Y.1
Maes, H.2
Sweldens, C.3
-
78
-
-
33750579081
-
Effect of regular phosphodiesterase type 5 inhibition in hypertension
-
DOI 10.1161/01.HYP.0000239816.13007.c9, PII 0000426820061000000021
-
Oliver JJ, Melville VP, Webb DJ. Effect of regular phosphodiesterase type 5 inhibition in hypertension. Hypertension. 2006;48:622-7. (Pubitemid 44843865)
-
(2006)
Hypertension
, vol.48
, Issue.4
, pp. 622-627
-
-
Oliver, J.J.1
Melville, V.P.2
Webb, D.J.3
-
79
-
-
38349030422
-
Uncovering Pandora's vase: The growing problem of new toxicities from novel anticancer agents. The case of sorafenib and sunitinib
-
Porta C, Paglino C, Imarisio I, Bonomi L. Uncovering Pandora's vase: The growing problem of new toxicities from novel anticancer agents. The case of sorafenib and sunitinib. Clin Exp Med. 2007;7:127-34.
-
(2007)
Clin Exp Med
, vol.7
, pp. 127-134
-
-
Porta, C.1
Paglino, C.2
Imarisio, I.3
Bonomi, L.4
-
80
-
-
80052917736
-
Evolution of renal function in patients treated with antiangiogenics after nephrectomy for renal cell carcinoma
-
Launay-Vacher V, Ayllon J, Janus N, et al. Evolution of renal function in patients treated with antiangiogenics after nephrectomy for renal cell carcinoma. Urol Oncol. 2011;29:492-4.
-
(2011)
Urol Oncol
, vol.29
, pp. 492-494
-
-
Launay-Vacher, V.1
Ayllon, J.2
Janus, N.3
-
81
-
-
80051537982
-
Safety and efficacy of molecularly targeted agents in patients with metastatic kidney cancer with renal dysfunction
-
Gupta S, Parsa V, Heilbrun LK, et al. Safety and efficacy of molecularly targeted agents in patients with metastatic kidney cancer with renal dysfunction. Anticancer Drugs. 2011;22:794-800.
-
(2011)
Anticancer Drugs.
, vol.22
, pp. 794-800
-
-
Gupta, S.1
Parsa, V.2
Heilbrun, L.K.3
-
82
-
-
80053350426
-
Anti-VEGF antibody treatment accelerates polycystic kidney disease
-
Raina S, Honer M, Kramer SD, et al. Anti-VEGF antibody treatment accelerates polycystic kidney disease. Am J Physiol Renal Physiol. 2011;301:F773-83.
-
(2011)
Am J Physiol Renal Physiol.
, vol.301
-
-
Raina, S.1
Honer, M.2
Kramer, S.D.3
|