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Volumn 281, Issue 1, 2014, Pages 115-128

Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer

Author keywords

AKT; cisplatin; gastric cancer; hypoxia inducible factor 1 ; survivin

Indexed keywords

CISPLATIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN KINASE B; SEPANTRONIUM BROMIDE; SHORT HAIRPIN RNA; SURVIVIN;

EID: 84891831293     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12577     Document Type: Article
Times cited : (79)

References (45)
  • 2
    • 82155164396 scopus 로고    scopus 로고
    • Treatment strategies in gastric cancer
    • Meyer HJ, &, Wike H, (2011) Treatment strategies in gastric cancer. Dtsch Arztebl Int 108, 698-706.
    • (2011) Dtsch Arztebl Int , vol.108 , pp. 698-706
    • Meyer, H.J.1    Wike, H.2
  • 3
    • 80054717683 scopus 로고    scopus 로고
    • The role of chemotherapy in metastatic gastric cancer
    • Pasini F, Fraccon AP, &, De Manzoni G, (2011) The role of chemotherapy in metastatic gastric cancer. Anticancer Res 31, 3543-3554.
    • (2011) Anticancer Res , vol.31 , pp. 3543-3554
    • Pasini, F.1    Fraccon, A.P.2    De Manzoni, G.3
  • 5
    • 0035400270 scopus 로고    scopus 로고
    • Mechanisms of resistance to cisplatin
    • Kartalou M, &, Essigmann JM, (2001) Mechanisms of resistance to cisplatin. Mutat Res 478, 23-43.
    • (2001) Mutat Res , vol.478 , pp. 23-43
    • Kartalou, M.1    Essigmann, J.M.2
  • 6
    • 35348827736 scopus 로고    scopus 로고
    • The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy
    • Hall MD, Okabe M, Shen DW, Liang XJ, &, Gottesman MM, (2008) The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy. Annu Rev Pharmacol Toxicol 48, 495-535.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 495-535
    • Hall, M.D.1    Okabe, M.2    Shen, D.W.3    Liang, X.J.4    Gottesman, M.M.5
  • 7
    • 84876096250 scopus 로고    scopus 로고
    • Targeting survivin in cancer
    • Altieri DC, (2013) Targeting survivin in cancer. Cancer Lett 332, 225-228.
    • (2013) Cancer Lett , vol.332 , pp. 225-228
    • Altieri, D.C.1
  • 8
    • 84888315981 scopus 로고    scopus 로고
    • TFF3 and survivin expressions associate with a lower survival rate in gastric cancer
    • in press. doi: 10.1007/s10238-012-0210-9.
    • Meng JR, Tang HZ, Zhou KZ, Shen WH, &, Guo HY, (2012) TFF3 and survivin expressions associate with a lower survival rate in gastric cancer. Clin Exp Med in press. doi: 10.1007/s10238-012-0210-9.
    • (2012) Clin Exp Med
    • Meng, J.R.1    Tang, H.Z.2    Zhou, K.Z.3    Shen, W.H.4    Guo, H.Y.5
  • 9
    • 0037267333 scopus 로고    scopus 로고
    • Validating survivin as a cancer therapeutic target
    • Altieri DC, (2003) Validating survivin as a cancer therapeutic target. Nat Rev Cancer 3, 46-54.
    • (2003) Nat Rev Cancer , vol.3 , pp. 46-54
    • Altieri, D.C.1
  • 10
    • 84880510067 scopus 로고    scopus 로고
    • Angiopoietin2 enhances doxorubin resistance in HepG2 cells by upregulating survivin and Ref-1 via MSK1 activation
    • Li T, Liu Z, Jiang K, &, Ruan Q, (2013) Angiopoietin2 enhances doxorubin resistance in HepG2 cells by upregulating survivin and Ref-1 via MSK1 activation. Cancer Lett 337, 276-284.
    • (2013) Cancer Lett , vol.337 , pp. 276-284
    • Li, T.1    Liu, Z.2    Jiang, K.3    Ruan, Q.4
  • 11
    • 84879289773 scopus 로고    scopus 로고
    • Suppression of survivin induced by BCR-ABL/JAK2/STAT3 pathway sensitizes Imatinib-resistant CML cells to different cytotoxic drugs
    • Stella S, Tirrò E, Conte E, Stagno F, Di Raimondo F, Manzella L, &, Vigneri P, (2013) Suppression of survivin induced by BCR-ABL/JAK2/STAT3 pathway sensitizes Imatinib-resistant CML cells to different cytotoxic drugs. Mol Cancer Ther 12, 1085-1098.
    • (2013) Mol Cancer Ther , vol.12 , pp. 1085-1098
    • Stella, S.1    Tirrò, E.2    Conte, E.3    Stagno, F.4    Di Raimondo, F.5    Manzella, L.6    Vigneri, P.7
  • 12
    • 77957194642 scopus 로고    scopus 로고
    • A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy
    • Cheung CH, Sun X, Kanwar JR, Bai JZ, Cheng L, &, Krissansen GW, (2010) A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy. Cancer Cell Int 10, 36.
    • (2010) Cancer Cell Int , vol.10 , pp. 36
    • Cheung, C.H.1    Sun, X.2    Kanwar, J.R.3    Bai, J.Z.4    Cheng, L.5    Krissansen, G.W.6
  • 13
    • 40949142209 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factors in tumorigenesis
    • Rankin EB, &, Giaccia AJ, (2008) The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 15, 678-685.
    • (2008) Cell Death Differ , vol.15 , pp. 678-685
    • Rankin, E.B.1    Giaccia, A.J.2
  • 14
    • 49649115935 scopus 로고    scopus 로고
    • Hypoxia-inducible transcription factor-2α in endothelial cells regulates tumor neovascrularization through activation of ephrin A1
    • Yamashita T, Ohneda K, Nagano M, Miyoshi C, Kaneko N, Miwa Y, Yamamoto M, Ohneda O, &, Fujii-Kuriyama Y, (2008) Hypoxia-inducible transcription factor-2α in endothelial cells regulates tumor neovascrularization through activation of ephrin A1. J Biol Chem 283, 18926-18936.
    • (2008) J Biol Chem , vol.283 , pp. 18926-18936
    • Yamashita, T.1    Ohneda, K.2    Nagano, M.3    Miyoshi, C.4    Kaneko, N.5    Miwa, Y.6    Yamamoto, M.7    Ohneda, O.8    Fujii-Kuriyama, Y.9
  • 15
    • 78349272461 scopus 로고    scopus 로고
    • HIF-1 and HIF-2 transcription factors - Similar but not identical
    • Loboda A, Jozkowicz A, &, Dulak J, (2010) HIF-1 and HIF-2 transcription factors-similar but not identical. Mol Cells 29, 435-442.
    • (2010) Mol Cells , vol.29 , pp. 435-442
    • Loboda, A.1    Jozkowicz, A.2    Dulak, J.3
  • 16
    • 77957786826 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB
    • Rohwer N, Dame C, Haugstetter A, Wiedenmann B, Detjen K, Schmitt CA, &, Cramer T, (2010) Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB. PLoS ONE 5, e12038.
    • (2010) PLoS ONE , vol.5
    • Rohwer, N.1    Dame, C.2    Haugstetter, A.3    Wiedenmann, B.4    Detjen, K.5    Schmitt, C.A.6    Cramer, T.7
  • 17
    • 36949000697 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1α contributes to hypoxia-induced chemoresistance in gastric cancer
    • Liu L, Ning X, Sun L, Zhang H, Shi Y, Guo C, Han S, Liu J, Sun S, Han Z, et al,. (2008) Hypoxia-inducible factor-1α contributes to hypoxia-induced chemoresistance in gastric cancer. Cancer Sci 99, 121-128.
    • (2008) Cancer Sci , vol.99 , pp. 121-128
    • Liu, L.1    Ning, X.2    Sun, L.3    Zhang, H.4    Shi, Y.5    Guo, C.6    Han, S.7    Liu, J.8    Sun, S.9    Han, Z.10
  • 18
    • 54949123005 scopus 로고    scopus 로고
    • Antisense hypoxia-inducible factor 1α gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma
    • Liu F, Wang P, Jiang X, Tan G, Qiao H, Jiang H, Krissansen GW, &, Sun X, (2008) Antisense hypoxia-inducible factor 1α gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma. Cancer Sci 99, 2055-2061.
    • (2008) Cancer Sci , vol.99 , pp. 2055-2061
    • Liu, F.1    Wang, P.2    Jiang, X.3    Tan, G.4    Qiao, H.5    Jiang, H.6    Krissansen, G.W.7    Sun, X.8
  • 19
    • 77954815583 scopus 로고    scopus 로고
    • Antisense HIF-1 prevents acquired tumour resistance to the anti-angiogenic drug angiostatin
    • Sun X, Vale M, Jiang X, Gupta R, &, Krissansen GW, (2010) Antisense HIF-1 prevents acquired tumour resistance to the anti-angiogenic drug angiostatin. Cancer Gene Ther 17, 532-540.
    • (2010) Cancer Gene Ther , vol.17 , pp. 532-540
    • Sun, X.1    Vale, M.2    Jiang, X.3    Gupta, R.4    Krissansen, G.W.5
  • 20
    • 79959550744 scopus 로고    scopus 로고
    • Hypoxia-induced cisplatin resistance is reversible and growth rate independent in lung cancer cells
    • Wohlkoenig C, Leithner K, Deutsch A, Hrzenjak A, Olschewski A, &, Olschewski H, (2011) Hypoxia-induced cisplatin resistance is reversible and growth rate independent in lung cancer cells. Cancer Lett 308, 134-143.
    • (2011) Cancer Lett , vol.308 , pp. 134-143
    • Wohlkoenig, C.1    Leithner, K.2    Deutsch, A.3    Hrzenjak, A.4    Olschewski, A.5    Olschewski, H.6
  • 21
    • 84864294365 scopus 로고    scopus 로고
    • HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer
    • Liu Y, Bernauer AM, Yingling CM, &, Belinsky SA, (2012) HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer. Carcinogenesis 33, 1187-1192.
    • (2012) Carcinogenesis , vol.33 , pp. 1187-1192
    • Liu, Y.1    Bernauer, A.M.2    Yingling, C.M.3    Belinsky, S.A.4
  • 22
    • 84875256838 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1α-mediated activation of survivin in cervical cancer cells
    • Bai H, Ge S, Lu J, Qian G, &, Xu R, (2013) Hypoxia inducible factor-1α-mediated activation of survivin in cervical cancer cells. J Obstet Gynaecol Res 39, 555-563.
    • (2013) J Obstet Gynaecol Res , vol.39 , pp. 555-563
    • Bai, H.1    Ge, S.2    Lu, J.3    Qian, G.4    Xu, R.5
  • 23
    • 84879370462 scopus 로고    scopus 로고
    • HIF-1α knockdown by miRNA decreases survivin expression and inhibits A549 cell growth in vitro and in vivo
    • Li W, Chen YQ, Shen YB, Shu HM, Wang XJ, Zhao CL, &, Chen CJ, (2013) HIF-1α knockdown by miRNA decreases survivin expression and inhibits A549 cell growth in vitro and in vivo. Int J Mol Med 32, 271-280.
    • (2013) Int J Mol Med , vol.32 , pp. 271-280
    • Li, W.1    Chen, Y.Q.2    Shen, Y.B.3    Shu, H.M.4    Wang, X.J.5    Zhao, C.L.6    Chen, C.J.7
  • 24
    • 84878831559 scopus 로고    scopus 로고
    • Overcoming acquired resistance to anticancer therapy: Focus on the PI3K/AKT/mTOR pathway
    • Burris HA III, (2013) Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway. Cancer Chemother Pharmacol 71, 829-842.
    • (2013) Cancer Chemother Pharmacol , vol.71 , pp. 829-842
    • Burris III, H.A.1
  • 25
    • 84871675092 scopus 로고    scopus 로고
    • AKT as locus of cancer multidrug resistance and fragility
    • Radisavljevic Z, (2013) AKT as locus of cancer multidrug resistance and fragility. J Cell Physiol 228, 671-674.
    • (2013) J Cell Physiol , vol.228 , pp. 671-674
    • Radisavljevic, Z.1
  • 27
    • 84855661853 scopus 로고    scopus 로고
    • Activation of PI3 kinase/Akt/HIF-1α pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma
    • Jiao M, &, Nan KJ, (2012) Activation of PI3 kinase/Akt/HIF-1α pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma. Int J Oncol 40, 461-468.
    • (2012) Int J Oncol , vol.40 , pp. 461-468
    • Jiao, M.1    Nan, K.J.2
  • 29
    • 84868691831 scopus 로고    scopus 로고
    • Thimerosal-induced apoptosis in mouse C2C12 myoblast cells occurs through suppression of the PI3K/Akt/survivin pathway
    • Li WX, Chen SF, Chen LP, Yang GY, Li JT, Liu HZ, &, Zhu W, (2012) Thimerosal-induced apoptosis in mouse C2C12 myoblast cells occurs through suppression of the PI3K/Akt/survivin pathway. PLoS ONE 7, e49064.
    • (2012) PLoS ONE , vol.7
    • Li, W.X.1    Chen, S.F.2    Chen, L.P.3    Yang, G.Y.4    Li, J.T.5    Liu, H.Z.6    Zhu, W.7
  • 30
    • 53549127988 scopus 로고    scopus 로고
    • CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation
    • Roca H, Varsos Z, &, Pienta KJ, (2008) CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. J Biol Chem 283, 25057-25073.
    • (2008) J Biol Chem , vol.283 , pp. 25057-25073
    • Roca, H.1    Varsos, Z.2    Pienta, K.J.3
  • 31
    • 84874463929 scopus 로고    scopus 로고
    • Secretory clusterin contributes to oxaliplatin resistance by activating Akt pathway in hepatocellular carcinoma
    • Xiu P, Dong X, Dong X, Xu Z, Zhu H, Liu F, Wei Z, Zhai B, Kanwar JR, Jiang H, et al,. (2013) Secretory clusterin contributes to oxaliplatin resistance by activating Akt pathway in hepatocellular carcinoma. Cancer Sci 104, 375-382.
    • (2013) Cancer Sci , vol.104 , pp. 375-382
    • Xiu, P.1    Dong, X.2    Dong, X.3    Xu, Z.4    Zhu, H.5    Liu, F.6    Wei, Z.7    Zhai, B.8    Kanwar, J.R.9    Jiang, H.10
  • 33
    • 79957534572 scopus 로고    scopus 로고
    • Targeting hypoxia in cancer therapy
    • Wilson WR, &, Hay MP, (2011) Targeting hypoxia in cancer therapy. Nat Rev Cancer 11, 393-410.
    • (2011) Nat Rev Cancer , vol.11 , pp. 393-410
    • Wilson, W.R.1    Hay, M.P.2
  • 35
    • 77953158079 scopus 로고    scopus 로고
    • Distinct biological roles for the Akt family in mammary tumor progression
    • Dillon RL, &, Muller WJ, (2010) Distinct biological roles for the Akt family in mammary tumor progression. Cancer Res 70, 4260-4264.
    • (2010) Cancer Res , vol.70 , pp. 4260-4264
    • Dillon, R.L.1    Muller, W.J.2
  • 37
    • 3042743988 scopus 로고    scopus 로고
    • Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
    • Yang L, Dan HC, Sun M, Liu Q, Sun XM, Feldman RI, Hamilton AD, Polokoff M, Nicosia SV, Herlyn M, et al,. (2004) Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 64, 4394-4399.
    • (2004) Cancer Res , vol.64 , pp. 4394-4399
    • Yang, L.1    Dan, H.C.2    Sun, M.3    Liu, Q.4    Sun, X.M.5    Feldman, R.I.6    Hamilton, A.D.7    Polokoff, M.8    Nicosia, S.V.9    Herlyn, M.10
  • 38
    • 79955504184 scopus 로고    scopus 로고
    • Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes significant breast tumor regression in ErbB2 transgenic mice
    • Balasis ME, Forinash KD, Chen YA, Fulp WJ, Coppola D, Hamilton AD, Cheng JQ, &, Sebti SM, (2011) Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes significant breast tumor regression in ErbB2 transgenic mice. Clin Cancer Res 17, 2852-2862.
    • (2011) Clin Cancer Res , vol.17 , pp. 2852-2862
    • Balasis, M.E.1    Forinash, K.D.2    Chen, Y.A.3    Fulp, W.J.4    Coppola, D.5    Hamilton, A.D.6    Cheng, J.Q.7    Sebti, S.M.8
  • 39
    • 84872803114 scopus 로고    scopus 로고
    • Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo
    • Wei Z, Jiang X, Liu F, Qiao H, Zhou B, Zhai B, Zhang L, Zhang X, Han L, Jiang H, et al,. (2013) Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo. Tumor Biol 34, 181-192.
    • (2013) Tumor Biol , vol.34 , pp. 181-192
    • Wei, Z.1    Jiang, X.2    Liu, F.3    Qiao, H.4    Zhou, B.5    Zhai, B.6    Zhang, L.7    Zhang, X.8    Han, L.9    Jiang, H.10
  • 40
    • 84877607377 scopus 로고    scopus 로고
    • Anti-cancer effects of newly developed chemotherapeutic agent, glycoconjugated palladium (II) complex, against cisplatin-resistant gastric cancer cells
    • Tanaka M, Kataoka H, Yano S, Ohi H, Kawamoto K, Shibahara T, Mizoshita T, Mori Y, Tanida S, Kamiya T, et al,. (2013) Anti-cancer effects of newly developed chemotherapeutic agent, glycoconjugated palladium (II) complex, against cisplatin-resistant gastric cancer cells. BMC Cancer 13, 237.
    • (2013) BMC Cancer , vol.13 , pp. 237
    • Tanaka, M.1    Kataoka, H.2    Yano, S.3    Ohi, H.4    Kawamoto, K.5    Shibahara, T.6    Mizoshita, T.7    Mori, Y.8    Tanida, S.9    Kamiya, T.10
  • 41
    • 84873307557 scopus 로고    scopus 로고
    • STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells
    • Wei Z, Jiang X, Qiao H, Zhai B, Zhang L, Zhang Q, Wu Y, Jiang H, &, Sun X, (2013) STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells. Cell Signal 25, 931-938.
    • (2013) Cell Signal , vol.25 , pp. 931-938
    • Wei, Z.1    Jiang, X.2    Qiao, H.3    Zhai, B.4    Zhang, L.5    Zhang, Q.6    Wu, Y.7    Jiang, H.8    Sun, X.9
  • 42
    • 84859712679 scopus 로고    scopus 로고
    • Downregulating hypoxia-inducible factor-2α improves the efficacy of doxorubicin to treat hepatocellular carcinoma
    • He C, Sun XP, Qiao H, Jiang X, Wang D, Jin X, Dong X, Wang J, Jiang H, &, Sun X, (2012) Downregulating hypoxia-inducible factor-2α improves the efficacy of doxorubicin to treat hepatocellular carcinoma. Cancer Sci 103, 528-534.
    • (2012) Cancer Sci , vol.103 , pp. 528-534
    • He, C.1    Sun, X.P.2    Qiao, H.3    Jiang, X.4    Wang, D.5    Jin, X.6    Dong, X.7    Wang, J.8    Jiang, H.9    Sun, X.10
  • 43
    • 84867504415 scopus 로고    scopus 로고
    • Synergistic effects of ABT-737 and arsenic trioxide in inducing apoptosis of gastric cancer cells
    • Sun X-P, He C, Qiao H, Jiang X, Jiang H, &, Sun X, (2012) Synergistic effects of ABT-737 and arsenic trioxide in inducing apoptosis of gastric cancer cells. J Int Med Res 40, 1251-1264.
    • (2012) J Int Med Res , vol.40 , pp. 1251-1264
    • Sun, X.-P.1    He, C.2    Qiao, H.3    Jiang, X.4    Jiang, H.5    Sun, X.6
  • 44
    • 84874053045 scopus 로고    scopus 로고
    • Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice
    • Ehteda A, Galettis P, Pillai K, &, Morris DL, (2013) Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice. BMC Cancer 13, 86.
    • (2013) BMC Cancer , vol.13 , pp. 86
    • Ehteda, A.1    Galettis, P.2    Pillai, K.3    Morris, D.L.4
  • 45
    • 84865793850 scopus 로고    scopus 로고
    • Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer
    • Wang Q, Li SH, Wang H, Xiao Y, Sahin O, Brady SW, Li P, Ge H, Jaffee EM, Muller WJ, et al,. (2012) Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res 72, 4417-4428.
    • (2012) Cancer Res , vol.72 , pp. 4417-4428
    • Wang, Q.1    Li, S.H.2    Wang, H.3    Xiao, Y.4    Sahin, O.5    Brady, S.W.6    Li, P.7    Ge, H.8    Jaffee, E.M.9    Muller, W.J.10


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