-
1
-
-
84906279651
-
Metabolically healthy and unhealthy obese-the 2013 Stock Conference report
-
Samocha-Bonet D, Dixit VD, Kahn CR, et al., Metabolically healthy and unhealthy obese-the 2013 Stock Conference report. Obes Rev 2014; 15: 697-708.
-
(2014)
Obes Rev
, vol.15
, pp. 697-708
-
-
Samocha-Bonet, D.1
Dixit, V.D.2
Kahn, C.R.3
-
2
-
-
84864293537
-
Role of intramyocelluar lipids in human health
-
Coen PM, Goodpaster BH., Role of intramyocelluar lipids in human health. Trends Endocrinol Metab 2012; 23: 391-398.
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 391-398
-
-
Coen, P.M.1
Goodpaster, B.H.2
-
4
-
-
84907984591
-
CerS2 haploinsufficiency inhibits beta-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance
-
Raichur S, Wang ST, Chan PW, et al., CerS2 haploinsufficiency inhibits beta-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell Metab 2014; 20: 687-695.
-
(2014)
Cell Metab
, vol.20
, pp. 687-695
-
-
Raichur, S.1
Wang, S.T.2
Chan, P.W.3
-
5
-
-
84878871217
-
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
-
Turner N, Kowalski GM, Leslie SJ, et al., Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding. Diabetologia 2013; 56: 1638-1648.
-
(2013)
Diabetologia
, vol.56
, pp. 1638-1648
-
-
Turner, N.1
Kowalski, G.M.2
Leslie, S.J.3
-
6
-
-
84907978697
-
Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance
-
Turpin SM, Nicholls HT, Willmes DM, et al., Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metab 2014; 20: 678-686.
-
(2014)
Cell Metab
, vol.20
, pp. 678-686
-
-
Turpin, S.M.1
Nicholls, H.T.2
Willmes, D.M.3
-
7
-
-
84862330756
-
Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans
-
Bergman BC, Hunerdosse DM, Kerege A, et al., Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans. Diabetologia 2012; 55: 1140-1150.
-
(2012)
Diabetologia
, vol.55
, pp. 1140-1150
-
-
Bergman, B.C.1
Hunerdosse, D.M.2
Kerege, A.3
-
8
-
-
77449161528
-
Insulin resistance is associated with higher intramyocellular triglycerides in type i but not type II myocytes concomitant with higher ceramide content
-
Coen PM, Dube JJ, Amati F, et al., Insulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content. Diabetes 2010; 59: 80-88.
-
(2010)
Diabetes
, vol.59
, pp. 80-88
-
-
Coen, P.M.1
Dube, J.J.2
Amati, F.3
-
9
-
-
34147145049
-
Short-term manipulation of plasma free fatty acids does not change skeletal muscle concentrations of ceramide and glucosylceramide in lean and overweight subjects
-
Serlie MJ, Meijer AJ, Groener JE, et al., Short-term manipulation of plasma free fatty acids does not change skeletal muscle concentrations of ceramide and glucosylceramide in lean and overweight subjects. J Clin Endocrinol Metab 2007; 92: 1524-1529.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1524-1529
-
-
Serlie, M.J.1
Meijer, A.J.2
Groener, J.E.3
-
10
-
-
44749085396
-
Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity
-
Skovbro M, Baranowski M, Skov-Jensen C, et al., Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity. Diabetologia 2008; 51: 1253-1260.
-
(2008)
Diabetologia
, vol.51
, pp. 1253-1260
-
-
Skovbro, M.1
Baranowski, M.2
Skov-Jensen, C.3
-
11
-
-
85027940419
-
Lipidomics is providing new insight into the metabolic syndrome and its sequelae
-
Meikle PJ, Christopher MJ., Lipidomics is providing new insight into the metabolic syndrome and its sequelae. Curr Opin Lipidol 2011; 22: 210-215.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 210-215
-
-
Meikle, P.J.1
Christopher, M.J.2
-
12
-
-
84899554139
-
Plasma lipidome is independently associated with variability in metabolic syndrome in Mexican American families
-
Kulkarni H, Meikle PJ, Mamtani M, et al., Plasma lipidome is independently associated with variability in metabolic syndrome in Mexican American families. J Lipid Res 2014; 55: 939-946.
-
(2014)
J Lipid Res
, vol.55
, pp. 939-946
-
-
Kulkarni, H.1
Meikle, P.J.2
Mamtani, M.3
-
13
-
-
84884678009
-
Plasma lipid profiling shows similar associations with prediabetes and type 2 diabetes
-
Meikle PJ, Wong G, Barlow CK, et al., Plasma lipid profiling shows similar associations with prediabetes and type 2 diabetes. PLoS One 2013; 8: e74341
-
(2013)
PLoS One
, vol.8
, pp. e74341
-
-
Meikle, P.J.1
Wong, G.2
Barlow, C.K.3
-
14
-
-
84876471343
-
Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects
-
Tonks KT, Ng Y, Miller S, et al., Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects. Diabetologia 2013; 56: 875-885.
-
(2013)
Diabetologia
, vol.56
, pp. 875-885
-
-
Tonks, K.T.1
Ng, Y.2
Miller, S.3
-
15
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry RA, Hobbs B, Collin F, et al., Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4: 249-264.
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
-
16
-
-
84862250978
-
Using control genes to correct for unwanted variation in microarray data
-
Gagnon-Bartsch JA, Speed TP., Using control genes to correct for unwanted variation in microarray data. Biostatistics (Oxford, England) 2012; 13: 539-552.
-
(2012)
Biostatistics (Oxford, England)
, vol.13
, pp. 539-552
-
-
Gagnon-Bartsch, J.A.1
Speed, T.P.2
-
17
-
-
84891760956
-
Data, information, knowledge and principle: Back to metabolism in KEGG
-
Kanehisa M, Goto S, Sato Y, et al., Data, information, knowledge and principle: back to metabolism in KEGG. Nucleic Acids Res 2014; 42: D199-D205.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D199-D205
-
-
Kanehisa, M.1
Goto, S.2
Sato, Y.3
-
18
-
-
0038692119
-
Human housekeeping genes are compact
-
Eisenberg E, Levanon EY., Human housekeeping genes are compact. Trends Genet 2003; 19: 362-365.
-
(2003)
Trends Genet
, vol.19
, pp. 362-365
-
-
Eisenberg, E.1
Levanon, E.Y.2
-
19
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth GK., Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004; 3: Article3
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
, pp. Article3
-
-
Smyth, G.K.1
-
20
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, et al., PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003; 34: 267-273.
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
-
21
-
-
84889690537
-
The effect of short-term overfeeding on serum lipids in healthy humans
-
Heilbronn LK, Coster AC, Campbell LV, et al., The effect of short-term overfeeding on serum lipids in healthy humans. Obesity 2013; 21: E649-E659.
-
(2013)
Obesity
, vol.21
, pp. E649-E659
-
-
Heilbronn, L.K.1
Coster, A.C.2
Campbell, L.V.3
-
22
-
-
41949140023
-
Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
-
Laviad EL, Albee L, Pankova-Kholmyansky I, et al., Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 2008; 283: 5677-5684.
-
(2008)
J Biol Chem
, vol.283
, pp. 5677-5684
-
-
Laviad, E.L.1
Albee, L.2
Pankova-Kholmyansky, I.3
-
23
-
-
73249127400
-
Skeletal muscle lipogenic protein expression is not different between lean and obese individuals: A potential factor in ceramide accumulation
-
Thrush AB, Brindley DN, Chabowski A, et al., Skeletal muscle lipogenic protein expression is not different between lean and obese individuals: a potential factor in ceramide accumulation. J Clin Endocrinol Metab 2009; 94: 5053-5061.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 5053-5061
-
-
Thrush, A.B.1
Brindley, D.N.2
Chabowski, A.3
-
24
-
-
80053403320
-
Skeletal-muscle triglycerides, diacylglycerols, and ceramides in insulin resistance
-
Amati F, Dubé JJ, Carnero EA, et al., Skeletal-muscle triglycerides, diacylglycerols, and ceramides in insulin resistance. Diabetes 2011; 60: 2588-2597.
-
(2011)
Diabetes
, vol.60
, pp. 2588-2597
-
-
Amati, F.1
Dubé, J.J.2
Carnero, E.A.3
-
25
-
-
0346729968
-
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
-
Adams JM, 2nd, Pratipanawatr T, Berria R, et al., Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 2004; 53: 25-31.
-
(2004)
Diabetes
, vol.53
, pp. 25-31
-
-
Adams, J.M.1
Pratipanawatr, T.2
Berria, R.3
-
26
-
-
79954632229
-
Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide
-
Dube JJ, Amati F, Toledo FG, et al., Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide. Diabetologia 2011; 54: 1147-1156.
-
(2011)
Diabetologia
, vol.54
, pp. 1147-1156
-
-
Dube, J.J.1
Amati, F.2
Toledo, F.G.3
-
27
-
-
84962056389
-
Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning and Insulin Sensitivity Following Gastric Bypass Surgery
-
Coen PM, Menshikova EV, Distefano G, Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning and Insulin Sensitivity Following Gastric Bypass Surgery. Diabetes 2015; 64: 3737-3750.
-
(2015)
Diabetes
, vol.64
, pp. 3737-3750
-
-
Coen, P.M.1
Menshikova, E.V.2
Distefano, G.3
-
28
-
-
79955487247
-
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
-
Holland WL, Bikman BT, Wang L-P, et al., Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest 2011; 121: 1858-1870.
-
(2011)
J Clin Invest
, vol.121
, pp. 1858-1870
-
-
Holland, W.L.1
Bikman, B.T.2
Wang, L.-P.3
-
29
-
-
78651260799
-
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
-
Holland WL, Miller RA, Wang ZV, et al., Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nat Med 2011; 17: 55-63.
-
(2011)
Nat Med
, vol.17
, pp. 55-63
-
-
Holland, W.L.1
Miller, R.A.2
Wang, Z.V.3
-
30
-
-
84877272187
-
An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice
-
Holland WL, Adams AC, Brozinick JT, et al., An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice. Cell Metab 2013; 17: 790-797.
-
(2013)
Cell Metab
, vol.17
, pp. 790-797
-
-
Holland, W.L.1
Adams, A.C.2
Brozinick, J.T.3
-
31
-
-
84873029099
-
Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance
-
Boon J, Hoy AJ, Stark R, et al., Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance. Diabetes 2012; 62: 401-410.
-
(2012)
Diabetes
, vol.62
, pp. 401-410
-
-
Boon, J.1
Hoy, A.J.2
Stark, R.3
-
32
-
-
84939430145
-
Serum sphingolipids: Relationships to insulin sensitivity and changes with exercise in humans
-
Bergman BC, Brozinick JT, Strauss A, et al., Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans. Am J Physiol Endocrinol Metab 2015; 309: E398-E408.
-
(2015)
Am J Physiol Endocrinol Metab
, vol.309
, pp. E398-E408
-
-
Bergman, B.C.1
Brozinick, J.T.2
Strauss, A.3
-
33
-
-
64349124701
-
Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry
-
Wiesner P, Leidl K, Boettcher A, Schmitz G, et al., Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry. J Lipid Res 2009; 50: 574-585.
-
(2009)
J Lipid Res
, vol.50
, pp. 574-585
-
-
Wiesner, P.1
Leidl, K.2
Boettcher, A.3
Schmitz, G.4
-
34
-
-
84873042769
-
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach
-
Floegel A, Stefan N, Yu Z, et al., Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach. Diabetes 2013; 62: 639-648.
-
(2013)
Diabetes
, vol.62
, pp. 639-648
-
-
Floegel, A.1
Stefan, N.2
Yu, Z.3
-
35
-
-
84882959698
-
Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver
-
Lehmann R, Franken H, Dammeier S, et al., Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver. Diabetes Care 2013; 36: 2331-2338.
-
(2013)
Diabetes Care
, vol.36
, pp. 2331-2338
-
-
Lehmann, R.1
Franken, H.2
Dammeier, S.3
-
36
-
-
84890116926
-
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids
-
Oresic M, Hyotylainen T, Kotronen A, et al., Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids. Diabetologia 2013; 56: 2266-2274.
-
(2013)
Diabetologia
, vol.56
, pp. 2266-2274
-
-
Oresic, M.1
Hyotylainen, T.2
Kotronen, A.3
-
37
-
-
36349024819
-
A lipidomic analysis of nonalcoholic fatty liver disease
-
Puri P, Baillie RA, Wiest MM, et al., A lipidomic analysis of nonalcoholic fatty liver disease. Hepatology 2007; 46: 1081-1090.
-
(2007)
Hepatology
, vol.46
, pp. 1081-1090
-
-
Puri, P.1
Baillie, R.A.2
Wiest, M.M.3
-
38
-
-
70449715632
-
Diabetes mellitus is associated with increased intramyocellular triglyceride, but not diglyceride, content in obese humans
-
Anastasiou CA, Kavouras SA, Lentzas Y, et al., Diabetes mellitus is associated with increased intramyocellular triglyceride, but not diglyceride, content in obese humans. Metabolism 2009; 58: 1636-1642.
-
(2009)
Metabolism
, vol.58
, pp. 1636-1642
-
-
Anastasiou, C.A.1
Kavouras, S.A.2
Lentzas, Y.3
-
39
-
-
79953329970
-
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans
-
Rhee EP, Cheng S, Larson MG, et al., Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans. J Clin Invest 2011; 121: 1402-1411.
-
(2011)
J Clin Invest
, vol.121
, pp. 1402-1411
-
-
Rhee, E.P.1
Cheng, S.2
Larson, M.G.3
|