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Volumn 64, Issue 11, 2015, Pages 3737-3750

Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN; DIACYLGLYCEROL; INSULIN; LIPID; SPHINGOLIPID; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL;

EID: 84962056389     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0809     Document Type: Article
Times cited : (130)

References (57)
  • 1
    • 10744222607 scopus 로고    scopus 로고
    • Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus
    • discussion 484-485
    • Schauer PR, Burguera B, Ikramuddin S, et al. Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg 2003;238:467-484; discussion 484-485
    • (2003) Ann Surg , vol.238 , pp. 467-484
    • Schauer, P.R.1    Burguera, B.2    Ikramuddin, S.3
  • 2
    • 84866004714 scopus 로고    scopus 로고
    • Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass
    • Dirksen C, Jørgensen NB, Bojsen-Møller KN, et al. Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass. Diabetologia 2012;55:1890-1901
    • (2012) Diabetologia , vol.55 , pp. 1890-1901
    • Dirksen, C.1    Jørgensen, N.B.2    Bojsen-Møller, K.N.3
  • 3
    • 79960913296 scopus 로고    scopus 로고
    • Early and longer term effects of gastric bypass surgery on tissue-specific insulin sensitivity and beta cell function in morbidly obese patients with and without type 2 diabetes
    • Camastra S, Gastaldelli A, Mari A, et al. Early and longer term effects of gastric bypass surgery on tissue-specific insulin sensitivity and beta cell function in morbidly obese patients with and without type 2 diabetes. Diabetologia 2011;54:2093-2102
    • (2011) Diabetologia , vol.54 , pp. 2093-2102
    • Camastra, S.1    Gastaldelli, A.2    Mari, A.3
  • 4
    • 84920430312 scopus 로고    scopus 로고
    • Clinical trial demonstrates exercise following bariatric surgery improves insulin sensitivity
    • Coen PM, Tanner CJ, Helbling NL, et al. Clinical trial demonstrates exercise following bariatric surgery improves insulin sensitivity. J Clin Invest 2015;125:248-257
    • (2015) J Clin Invest , vol.125 , pp. 248-257
    • Coen, P.M.1    Tanner, C.J.2    Helbling, N.L.3
  • 5
    • 84875412120 scopus 로고    scopus 로고
    • Mitochondrial deficiency is associated with insulin resistance
    • Goodpaster BH. Mitochondrial deficiency is associated with insulin resistance. Diabetes 2013;62:1032-1035
    • (2013) Diabetes , vol.62 , pp. 1032-1035
    • Goodpaster, B.H.1
  • 6
    • 37449020075 scopus 로고    scopus 로고
    • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
    • Koves TR, Ussher JR, Noland RC, et al. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 2008;7:45-56
    • (2008) Cell Metab , vol.7 , pp. 45-56
    • Koves, T.R.1    Ussher, J.R.2    Noland, R.C.3
  • 7
    • 84864293537 scopus 로고    scopus 로고
    • Role of intramyocelluar lipids in human health
    • Coen PM, Goodpaster BH. Role of intramyocelluar lipids in human health. Trends Endocrinol Metab 2012;23:391-398
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 391-398
    • Coen, P.M.1    Goodpaster, B.H.2
  • 8
    • 84860482342 scopus 로고    scopus 로고
    • A ceramide-centric view of insulin resistance
    • Chavez JA, Summers SA. A ceramide-centric view of insulin resistance. Cell Metab 2012;15:585-594
    • (2012) Cell Metab , vol.15 , pp. 585-594
    • Chavez, J.A.1    Summers, S.A.2
  • 9
    • 0346729968 scopus 로고    scopus 로고
    • Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
    • Adams JM 2nd, Pratipanawatr T, Berria R, et al. Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 2004;53:25-31
    • (2004) Diabetes , vol.53 , pp. 25-31
    • Adams, J.M.1    Pratipanawatr, T.2    Berria, R.3
  • 10
    • 84887165238 scopus 로고    scopus 로고
    • Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity
    • Coen PM, Hames KC, Leachman EM, et al. Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity. Obesity (Silver Spring) 2013;21:2362-2371
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 2362-2371
    • Coen, P.M.1    Hames, K.C.2    Leachman, E.M.3
  • 11
    • 44749085396 scopus 로고    scopus 로고
    • Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity
    • Skovbro M, Baranowski M, Skov-Jensen C, et al. Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity. Diabetologia 2008;51:1253-1260
    • (2008) Diabetologia , vol.51 , pp. 1253-1260
    • Skovbro, M.1    Baranowski, M.2    Skov-Jensen, C.3
  • 12
    • 0036300538 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
    • Itani SI, Ruderman NB, Schmieder F, Boden G. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 2002;51:2005-2011
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Schmieder, F.3    Boden, G.4
  • 13
    • 77449161528 scopus 로고    scopus 로고
    • Insulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content
    • Coen PM, Dubé JJ, Amati F, et al. Insulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content. Diabetes 2010;59:80-88
    • (2010) Diabetes , vol.59 , pp. 80-88
    • Coen, P.M.1    Dubé, J.J.2    Amati, F.3
  • 14
    • 80053403320 scopus 로고    scopus 로고
    • Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: Another paradox in endurancetrained athletes?
    • Amati F, Dubé JJ, Alvarez-Carnero E, et al. Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: another paradox in endurancetrained athletes? Diabetes 2011;60:2588-2597
    • (2011) Diabetes , vol.60 , pp. 2588-2597
    • Amati, F.1    Dubé, J.J.2    Alvarez-Carnero, E.3
  • 15
    • 84884530503 scopus 로고    scopus 로고
    • The role of weight loss and exercise in correcting skeletal muscle mitochondrial abnormalities in obesity, diabetes and aging
    • Toledo FG, Goodpaster BH. The role of weight loss and exercise in correcting skeletal muscle mitochondrial abnormalities in obesity, diabetes and aging. Mol Cell Endocrinol 2013;379:30-34
    • (2013) Mol Cell Endocrinol , vol.379 , pp. 30-34
    • Toledo, F.G.1    Goodpaster, B.H.2
  • 16
    • 33947710793 scopus 로고    scopus 로고
    • Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
    • Civitarese AE, Carling S, Heilbronn LK, et al.; CALERIE Pennington Team. Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Med 2007;4:e76
    • (2007) PLoS Med , vol.4 , pp. e76
    • Civitarese, A.E.1    Carling, S.2    Heilbronn, L.K.3
  • 17
    • 67651123214 scopus 로고    scopus 로고
    • Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
    • Rabøl R, Svendsen PF, Skovbro M, et al. Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss. Metabolism 2009;58:1145-1152
    • (2009) Metabolism , vol.58 , pp. 1145-1152
    • Rabøl, R.1    Svendsen, P.F.2    Skovbro, M.3
  • 18
    • 42449094965 scopus 로고    scopus 로고
    • Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
    • Toledo FG, Menshikova EV, Azuma K, et al. Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 2008;57:987-994
    • (2008) Diabetes , vol.57 , pp. 987-994
    • Toledo, F.G.1    Menshikova, E.V.2    Azuma, K.3
  • 19
  • 20
    • 84890125598 scopus 로고    scopus 로고
    • Bariatric surgery rapidly improves mitochondrial respiration in morbidly obese patients
    • Nijhawan S, Richards W, O'Hea MF, Audia JP, Alvarez DF. Bariatric surgery rapidly improves mitochondrial respiration in morbidly obese patients. Surg Endosc 2013;27:4569-4573
    • (2013) Surg Endosc , vol.27 , pp. 4569-4573
    • Nijhawan, S.1    Richards, W.2    O'Hea, M.F.3    Audia, J.P.4    Alvarez, D.F.5
  • 23
    • 0042266366 scopus 로고    scopus 로고
    • Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity
    • Short KR, Vittone JL, Bigelow ML, et al. Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 2003;52:1888-1896
    • (2003) Diabetes , vol.52 , pp. 1888-1896
    • Short, K.R.1    Vittone, J.L.2    Bigelow, M.L.3
  • 24
  • 25
    • 33746271951 scopus 로고    scopus 로고
    • Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatographytandem mass spectrometry
    • Bielawski J, Szulc ZM, Hannun YA, Bielawska A. Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatographytandem mass spectrometry. Methods 2006;39:82-91
    • (2006) Methods , vol.39 , pp. 82-91
    • Bielawski, J.1    Szulc, Z.M.2    Hannun, Y.A.3    Bielawska, A.4
  • 27
    • 84876979205 scopus 로고    scopus 로고
    • Weight loss after gastric bypass surgery in human obesity remodels promoter methylation
    • Barres R, Kirchner H, Rasmussen M, et al. Weight loss after gastric bypass surgery in human obesity remodels promoter methylation. Cell Reports 2013;3:1020-1027
    • (2013) Cell Reports , vol.3 , pp. 1020-1027
    • Barres, R.1    Kirchner, H.2    Rasmussen, M.3
  • 28
    • 34848869740 scopus 로고    scopus 로고
    • Upregulation of peroxisome proliferatoractivated receptor gamma coactivator gene (PGC1A) during weight loss is related to insulin sensitivity but not to energy expenditure
    • Gastaldi G, Russell A, Golay A, et al. Upregulation of peroxisome proliferatoractivated receptor gamma coactivator gene (PGC1A) during weight loss is related to insulin sensitivity but not to energy expenditure. Diabetologia 2007;50:2348-2355
    • (2007) Diabetologia , vol.50 , pp. 2348-2355
    • Gastaldi, G.1    Russell, A.2    Golay, A.3
  • 29
    • 77955508579 scopus 로고    scopus 로고
    • Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals
    • Phielix E, Meex R, Moonen-Kornips E, Hesselink MK, Schrauwen P. Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals. Diabetologia 2010;53:1714-1721
    • (2010) Diabetologia , vol.53 , pp. 1714-1721
    • Phielix, E.1    Meex, R.2    Moonen-Kornips, E.3    Hesselink, M.K.4    Schrauwen, P.5
  • 30
    • 33747702159 scopus 로고    scopus 로고
    • Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women
    • Toledo FG, Watkins S, Kelley DE. Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women. J Clin Endocrinol Metab 2006;91:3224-3227
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3224-3227
    • Toledo, F.G.1    Watkins, S.2    Kelley, D.E.3
  • 32
    • 84863960346 scopus 로고    scopus 로고
    • Free radical oxidation of cardiolipin: Chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases
    • Yin H, Zhu M. Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases. Free Radic Res 2012;46:959-974
    • (2012) Free Radic Res , vol.46 , pp. 959-974
    • Yin, H.1    Zhu, M.2
  • 33
    • 84942262554 scopus 로고    scopus 로고
    • Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training
    • Konopka AR, Asante A, Lanza IR, et al. Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 2015;64:2104-2115
    • (2015) Diabetes , vol.64 , pp. 2104-2115
    • Konopka, A.R.1    Asante, A.2    Lanza, I.R.3
  • 35
    • 84864098060 scopus 로고    scopus 로고
    • Myocardial regulation of lipidomic flux by cardiolipin synthase: Setting the beat for bioenergetic efficiency
    • Kiebish MA, Yang K, Sims HF, et al. Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency. J Biol Chem 2012;287:25086-25097
    • (2012) J Biol Chem , vol.287 , pp. 25086-25097
    • Kiebish, M.A.1    Yang, K.2    Sims, H.F.3
  • 36
    • 34447635483 scopus 로고
    • Do the mitochondria of obese individuals respond to exercise training?
    • Houmard JA. Do the mitochondria of obese individuals respond to exercise training? J Appl Physiol (1985) 2007;103:6-7
    • (1985) J Appl Physiol , vol.103 , pp. 6-7
    • Houmard, J.A.1
  • 37
    • 84920614732 scopus 로고    scopus 로고
    • Resistance to the beneficial effects of exercise in type 2 diabetes: Are some individuals programmed to fail?
    • Stephens NA, Sparks LM. Resistance to the beneficial effects of exercise in type 2 diabetes: are some individuals programmed to fail? J Clin Endocrinol Metab 2015;100:43-52
    • (2015) J Clin Endocrinol Metab , vol.100 , pp. 43-52
    • Stephens, N.A.1    Sparks, L.M.2
  • 38
    • 84895509212 scopus 로고    scopus 로고
    • Can we optimise the exercise training prescription to maximise improvements in mitochondria function and content?
    • Bishop DJ, Granata C, Eynon N. Can we optimise the exercise training prescription to maximise improvements in mitochondria function and content? Biochim Biophys Acta 2014;1840:1266-1275
    • (2014) Biochim Biophys Acta , vol.1840 , pp. 1266-1275
    • Bishop, D.J.1    Granata, C.2    Eynon, N.3
  • 39
    • 34447621360 scopus 로고
    • Characteristics of skeletal muscle mitochondrial biogenesis induced by moderateintensity exercise and weight loss in obesity
    • Menshikova EV, Ritov VB, Ferrell RE, Azuma K, Goodpaster BH, Kelley DE. Characteristics of skeletal muscle mitochondrial biogenesis induced by moderateintensity exercise and weight loss in obesity. J Appl Physiol (1985) 2007;103:21-27
    • (1985) J Appl Physiol , vol.103 , pp. 21-27
    • Menshikova, E.V.1    Ritov, V.B.2    Ferrell, R.E.3    Azuma, K.4    Goodpaster, B.H.5    Kelley, D.E.6
  • 40
    • 0034112806 scopus 로고    scopus 로고
    • Intramuscular lipid content is increased in obesity and decreased by weight loss
    • Goodpaster BH, Theriault R, Watkins SC, Kelley DE. Intramuscular lipid content is increased in obesity and decreased by weight loss. Metabolism 2000;49:467-472
    • (2000) Metabolism , vol.49 , pp. 467-472
    • Goodpaster, B.H.1    Theriault, R.2    Watkins, S.C.3    Kelley, D.E.4
  • 41
    • 34848921862 scopus 로고    scopus 로고
    • Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes
    • Straczkowski M, Kowalska I, Baranowski M, et al. Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes. Diabetologia 2007;50:2366-2373
    • (2007) Diabetologia , vol.50 , pp. 2366-2373
    • Straczkowski, M.1    Kowalska, I.2    Baranowski, M.3
  • 42
    • 0034612304 scopus 로고    scopus 로고
    • Ceramide interaction with the respiratory chain of heart mitochondria
    • Di Paola M, Cocco T, Lorusso M. Ceramide interaction with the respiratory chain of heart mitochondria. Biochemistry 2000;39:6660-6668
    • (2000) Biochemistry , vol.39 , pp. 6660-6668
    • Di Paola, M.1    Cocco, T.2    Lorusso, M.3
  • 43
    • 1842330849 scopus 로고    scopus 로고
    • Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
    • García-Ruiz C, Colell A, Marí M, Morales A, Fernández-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J Biol Chem 1997;272:11369-11377
    • (1997) J Biol Chem , vol.272 , pp. 11369-11377
    • García-Ruiz, C.1    Colell, A.2    Marí, M.3    Morales, A.4    Fernández-Checa, J.C.5
  • 44
    • 59649092928 scopus 로고    scopus 로고
    • Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death
    • Roy SS, Madesh M, Davies E, Antonsson B, Danial N, Hajnóczky G. Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death. Mol Cell 2009;33:377-388
    • (2009) Mol Cell , vol.33 , pp. 377-388
    • Roy, S.S.1    Madesh, M.2    Davies, E.3    Antonsson, B.4    Danial, N.5    Hajnóczky, G.6
  • 45
    • 79954632229 scopus 로고    scopus 로고
    • Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide
    • Dubé JJ, Amati F, Toledo FG, et al. Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide. Diabetologia 2011;54:1147-1156
    • (2011) Diabetologia , vol.54 , pp. 1147-1156
    • Dubé, J.J.1    Amati, F.2    Toledo, F.G.3
  • 46
    • 84870542506 scopus 로고    scopus 로고
    • Gastric bypass and banding equally improve insulin sensitivity and β cell function
    • Bradley D, Conte C, Mittendorfer B, et al. Gastric bypass and banding equally improve insulin sensitivity and β cell function. J Clin Invest 2012;122:4667-4674
    • (2012) J Clin Invest , vol.122 , pp. 4667-4674
    • Bradley, D.1    Conte, C.2    Mittendorfer, B.3
  • 47
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
    • Goodpaster BH, He J, Watkins S, Kelley DE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab 2001;86:5755-5761
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5755-5761
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3    Kelley, D.E.4
  • 48
    • 77950543816 scopus 로고    scopus 로고
    • Diacylglycerol-mediated insulin resistance
    • Erion DM, Shulman GI. Diacylglycerol-mediated insulin resistance. Nat Med 2010;16:400-402
    • (2010) Nat Med , vol.16 , pp. 400-402
    • Erion, D.M.1    Shulman, G.I.2
  • 49
    • 78650069737 scopus 로고    scopus 로고
    • Skeletal muscle lipase content and activity in obesity and type 2 diabetes
    • Jocken JW, Moro C, Goossens GH, et al. Skeletal muscle lipase content and activity in obesity and type 2 diabetes. J Clin Endocrinol Metab 2010;95:5449-5453
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 5449-5453
    • Jocken, J.W.1    Moro, C.2    Goossens, G.H.3
  • 50
    • 84862330756 scopus 로고    scopus 로고
    • Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans
    • Bergman BC, Hunerdosse DM, Kerege A, Playdon MC, Perreault L. Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans. Diabetologia 2012;55:1140-1150
    • (2012) Diabetologia , vol.55 , pp. 1140-1150
    • Bergman, B.C.1    Hunerdosse, D.M.2    Kerege, A.3    Playdon, M.C.4    Perreault, L.5
  • 51
    • 1842419225 scopus 로고
    • A glucose transport protein expressed predominately in insulin-responsive tissues
    • Charron MJ, Brosius FC 3rd, Alper SL, Lodish HF. A glucose transport protein expressed predominately in insulin-responsive tissues. Proc Natl Acad Sci U S A 1989;86:2535-2539
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2535-2539
    • Charron, M.J.1    Brosius, F.C.2    Alper, S.L.3    Lodish, H.F.4
  • 52
    • 0025302915 scopus 로고
    • Evidence against altered expression of GLUT1 or GLUT4 in skeletal muscle of patients with obesity or NIDDM
    • Pedersen O, Bak JF, Andersen PH, et al. Evidence against altered expression of GLUT1 or GLUT4 in skeletal muscle of patients with obesity or NIDDM. Diabetes 1990;39:865-870
    • (1990) Diabetes , vol.39 , pp. 865-870
    • Pedersen, O.1    Bak, J.F.2    Andersen, P.H.3
  • 53
    • 79957639938 scopus 로고    scopus 로고
    • Mechanisms for increased insulinstimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats
    • Sharma N, Arias EB, Bhat AD, et al. Mechanisms for increased insulinstimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats. Am J Physiol Endocrinol Metab 2011;300:E966-E978
    • (2011) Am J Physiol Endocrinol Metab , vol.300 , pp. E966-E978
    • Sharma, N.1    Arias, E.B.2    Bhat, A.D.3
  • 54
    • 0027328741 scopus 로고
    • GLUT 4 and insulin receptor binding and kinase activity in trained human muscle
    • Dela F, Handberg A, Mikines KJ, Vinten J, Galbo H. GLUT 4 and insulin receptor binding and kinase activity in trained human muscle. J Physiol 1993;469:615-624
    • (1993) J Physiol , vol.469 , pp. 615-624
    • Dela, F.1    Handberg, A.2    Mikines, K.J.3    Vinten, J.4    Galbo, H.5
  • 55
    • 0027175751 scopus 로고
    • Exercise training increases GLUT-4 protein concentration in previously sedentary middle-aged men
    • Houmard JA, Shinebarger MH, Dolan PL, et al. Exercise training increases GLUT-4 protein concentration in previously sedentary middle-aged men. Am J Physiol 1993;264:E896-E901
    • (1993) Am J Physiol , vol.264 , pp. E896-E901
    • Houmard, J.A.1    Shinebarger, M.H.2    Dolan, P.L.3
  • 56
    • 33750918305 scopus 로고    scopus 로고
    • Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes
    • O'Gorman DJ, Karlsson HK, McQuaid S, et al. Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes. Diabetologia 2006;49:2983-2992
    • (2006) Diabetologia , vol.49 , pp. 2983-2992
    • O'Gorman, D.J.1    Karlsson, H.K.2    McQuaid, S.3
  • 57
    • 80054956371 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis and GLUT4 expression by exercise
    • Holloszy JO. Regulation of mitochondrial biogenesis and GLUT4 expression by exercise. Compr Physiol 2011;1:921-940
    • (2011) Compr Physiol , vol.1 , pp. 921-940
    • Holloszy, J.O.1


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