메뉴 건너뛰기




Volumn 94, Issue 12, 2009, Pages 5053-5061

Skeletal muscle lipogenic protein expression is not different between lean and obese individuals: A potential factor in ceramide accumulation

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; CERAMIDE; DIACYLGLYCEROL; DIACYLGLYCEROL ACYLTRANSFERASE 1; FATTY ACID; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN; STEAROYL RETINOL BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 73249127400     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-2565     Document Type: Article
Times cited : (39)

References (44)
  • 2
    • 0032764784 scopus 로고    scopus 로고
    • Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
    • Perseghin G, Scifo P, DeCobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, Luzi L 1999 Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 48:1600-1606
    • (1999) Diabetes , vol.48 , pp. 1600-1606
    • Perseghin, G.1    Scifo, P.2    DeCobelli, F.3    Pagliato, E.4    Battezzati, A.5    Arcelloni, C.6    Vanzulli, A.7    Testolin, G.8    Pozza, G.9    Del Maschio, A.10    Luzi, L.11
  • 3
    • 29944445284 scopus 로고    scopus 로고
    • Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state
    • van Loon LJ, Goodpaster BH 2006 Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state. Pflugers Arch 451:606-616
    • (2006) Pflugers Arch , vol.451 , pp. 606-616
    • van Loon, L.J.1    Goodpaster, B.H.2
  • 4
    • 0038532298 scopus 로고    scopus 로고
    • A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • Chavez JA, Knotts TA, Wang LP, Li G, Dobrowsky RT, Florant GL, Summers SA 2003 A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J Biol Chem 278:10297-10303
    • (2003) J Biol Chem , vol.278 , pp. 10297-10303
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3    Li, G.4    Dobrowsky, R.T.5    Florant, G.L.6    Summers, S.A.7
  • 5
    • 0031964986 scopus 로고    scopus 로고
    • Effects of cell-permeable ceramides and tumor necrosis factor-α on insulin signaling and glucose uptake in 3T3-L1 adipocytes
    • Wang CN, O'Brien L, Brindley DN 1998 Effects of cell-permeable ceramides and tumor necrosis factor-α on insulin signaling and glucose uptake in 3T3-L1 adipocytes. Diabetes 47:24-31
    • (1998) Diabetes , vol.47 , pp. 24-31
    • Wang, C.N.1    O'Brien, L.2    Brindley, D.N.3
  • 6
    • 4344614649 scopus 로고    scopus 로고
    • Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
    • Stratford S, Hoehn KL, Liu F, Summers SA 2004 Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J Biol Chem 279:36608-36615
    • (2004) J Biol Chem , vol.279 , pp. 36608-36615
    • Stratford, S.1    Hoehn, K.L.2    Liu, F.3    Summers, S.A.4
  • 9
    • 34147145049 scopus 로고    scopus 로고
    • Short-term manipulation of plasma free fatty acids does not change skeletal muscle concentrations of ceramide and glucosylceramide in lean and overweight subjects
    • Serlie MJ, Meijer AJ, Groener JE, Duran M, Endert E, Fliers E, Aerts JM, Sauerwein HP 2007 Short-term manipulation of plasma free fatty acids does not change skeletal muscle concentrations of ceramide and glucosylceramide in lean and overweight subjects. J Clin Endocrinol Metab 92:1524-1529
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1524-1529
    • Serlie, M.J.1    Meijer, A.J.2    Groener, J.E.3    Duran, M.4    Endert, E.5    Fliers, E.6    Aerts, J.M.7    Sauerwein, H.P.8
  • 13
    • 4544355465 scopus 로고    scopus 로고
    • Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36
    • Bonen A, Parolin ML, Steinberg GR, Calles-Escandon J, Tandon NN, Glatz JF, Luiken JJ, Heigenhauser GJ, Dyck DJ 2004 Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36. FASEB J 18:1144-1146
    • (2004) FASEB J , vol.18 , pp. 1144-1146
    • Bonen, A.1    Parolin, M.L.2    Steinberg, G.R.3    Calles-Escandon, J.4    Tandon, N.N.5    Glatz, J.F.6    Luiken, J.J.7    Heigenhauser, G.J.8    Dyck, D.J.9
  • 14
    • 0028954296 scopus 로고
    • Triacylglycerol biosynthetic enzymes in lean and obese Zucker rats
    • Jamdar SC, Cao WF 1995 Triacylglycerol biosynthetic enzymes in lean and obese Zucker rats. Biochim Biophys Acta 1255:237-243
    • (1995) Biochim Biophys Acta , vol.1255 , pp. 237-243
    • Jamdar, S.C.1    Cao, W.F.2
  • 15
    • 33947542353 scopus 로고    scopus 로고
    • Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns
    • Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K 2007 Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J Biol Chem 282:3450-3457
    • (2007) J Biol Chem , vol.282 , pp. 3450-3457
    • Donkor, J.1    Sariahmetoglu, M.2    Dewald, J.3    Brindley, D.N.4    Reue, K.5
  • 16
    • 15944375261 scopus 로고    scopus 로고
    • Lipin, a lipodystrophy and obesity gene
    • Phan J, Reue K 2005 Lipin, a lipodystrophy and obesity gene. Cell Metab 1:73-83
    • (2005) Cell Metab , vol.1 , pp. 73-83
    • Phan, J.1    Reue, K.2
  • 17
    • 34249894505 scopus 로고    scopus 로고
    • Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
    • Liu L, Zhang Y, Chen N, Shi X, Tsang B, Yu YH 2007 Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance. J Clin Invest 117:1679-1689
    • (2007) J Clin Invest , vol.117 , pp. 1679-1689
    • Liu, L.1    Zhang, Y.2    Chen, N.3    Shi, X.4    Tsang, B.5    Yu, Y.H.6
  • 18
    • 33750906573 scopus 로고    scopus 로고
    • Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro
    • Pinnamaneni SK, Southgate RJ, Febbraio MA, Watt MJ 2006 Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro. Diabetologia 49:3027-3037
    • (2006) Diabetologia , vol.49 , pp. 3027-3037
    • Pinnamaneni, S.K.1    Southgate, R.J.2    Febbraio, M.A.3    Watt, M.J.4
  • 24
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J, Lees M, Sloane Stanley GH 1957 A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 26
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC 1985 Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 27
    • 34249915334 scopus 로고    scopus 로고
    • Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
    • Schenk S, Horowitz JF 2007 Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. J Clin Invest 117:1690-1698
    • (2007) J Clin Invest , vol.117 , pp. 1690-1698
    • Schenk, S.1    Horowitz, J.F.2
  • 28
    • 3042569137 scopus 로고    scopus 로고
    • Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
    • Lindén D, William-Olsson L, Rhedin M, Asztély AK, Clapham JC, Schreyer S 2004 Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis. J Lipid Res 45:1279-1288
    • (2004) J Lipid Res , vol.45 , pp. 1279-1288
    • Lindén, D.1    William-Olsson, L.2    Rhedin, M.3    Asztély, A.K.4    Clapham, J.C.5    Schreyer, S.6
  • 30
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: Master regulators of lipid homeostasis
    • Eberlé D, Hegarty B, Bossard P, Ferré P, Foufelle F 2004 SREBP transcription factors: master regulators of lipid homeostasis. Biochimie 86:839-848
    • (2004) Biochimie , vol.86 , pp. 839-848
    • Eberlé, D.1    Hegarty, B.2    Bossard, P.3    Ferré, P.4    Foufelle, F.5
  • 32
    • 0035029812 scopus 로고    scopus 로고
    • Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes
    • Ducluzeau PH, Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H 2001 Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes 50:1134-1142
    • (2001) Diabetes , vol.50 , pp. 1134-1142
    • Ducluzeau, P.H.1    Perretti, N.2    Laville, M.3    Andreelli, F.4    Vega, N.5    Riou, J.P.6    Vidal, H.7
  • 33
    • 0036300538 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
    • Itani SI, Ruderman NB, Schmieder F, Boden G 2002 Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α. Diabetes 51:2005-2011
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Schmieder, F.3    Boden, G.4
  • 34
    • 14644435061 scopus 로고    scopus 로고
    • Differential utilization of saturated palmitate and unsaturated oleate: Evidence from cultured myotubes
    • Gaster M, Rustan AC, Beck-Nielsen H 2005 Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes. Diabetes 54:648-656
    • (2005) Diabetes , vol.54 , pp. 648-656
    • Gaster, M.1    Rustan, A.C.2    Beck-Nielsen, H.3
  • 35
    • 0023248851 scopus 로고
    • Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat
    • Leyton J, Drury PJ, Crawford MA 1987 Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. Br J Nutr 57:383-393
    • (1987) Br J Nutr , vol.57 , pp. 383-393
    • Leyton, J.1    Drury, P.J.2    Crawford, M.A.3
  • 36
    • 0037261135 scopus 로고    scopus 로고
    • Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes
    • Mei J, Wang CN, O'Brien L, Brindley DN 2003 Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes. Int J Obes Relat Metab Disord 27:31-39
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 31-39
    • Mei, J.1    Wang, C.N.2    O'Brien, L.3    Brindley, D.N.4
  • 37
    • 34047276087 scopus 로고    scopus 로고
    • Effects of pioglitazone and high-fat diet on ceramide metabolism in rat skeletal muscles
    • Zendzian-Piotrowska M, Baranowski M, Zabielski P, Gorski J 2006 Effects of pioglitazone and high-fat diet on ceramide metabolism in rat skeletal muscles. J Physiol Pharmacol 57(Suppl 10):101-114
    • (2006) J Physiol Pharmacol , vol.57 , Issue.SUPPL. 10 , pp. 101-114
    • Zendzian-Piotrowska, M.1    Baranowski, M.2    Zabielski, P.3    Gorski, J.4
  • 38
    • 0029933665 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
    • Peraldi P, Hotamisligil GS, Buurman WA, White MF, Spiegelman BM 1996 Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem 271:13018-13022
    • (1996) J Biol Chem , vol.271 , pp. 13018-13022
    • Peraldi, P.1    Hotamisligil, G.S.2    Buurman, W.A.3    White, M.F.4    Spiegelman, B.M.5
  • 39
    • 0345118284 scopus 로고    scopus 로고
    • Cycloserine and threo-dihydrosphingosine inhibit TNF-α-induced cytotoxicity: Evidence for the importance of de novo ceramide synthesis in TNF-α signaling
    • Meyer SG, de Groot H 2003 Cycloserine and threo-dihydrosphingosine inhibit TNF-α-induced cytotoxicity: evidence for the importance of de novo ceramide synthesis in TNF-α signaling. Biochim Biophys Acta 1643:1-4
    • (2003) Biochim Biophys Acta , vol.1643 , pp. 1-4
    • Meyer, S.G.1    de Groot, H.2
  • 44
    • 0027395358 scopus 로고
    • The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids
    • Borkman M, Storlien LH, Pan DA, Jenkins AB, Chisholm DJ, Campbell LV 1993 The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N Engl J Med 328:238-244
    • (1993) N Engl J Med , vol.328 , pp. 238-244
    • Borkman, M.1    Storlien, L.H.2    Pan, D.A.3    Jenkins, A.B.4    Chisholm, D.J.5    Campbell, L.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.