메뉴 건너뛰기




Volumn 104, Issue , 2016, Pages 1-7

Micro-RNAs in cognition and cognitive disorders: Potential for novel biomarkers and therapeutics

Author keywords

Alzheimer's disease; Biomarkers; Cognitive dysfunctions; Learning and memory; miRNA

Indexed keywords

ANTAGOMIR; ANTISENSE OLIGONUCLEOTIDE; BIOLOGICAL MARKER; MICRORNA; MICRORNA 125B; MICRORNA 128B; MICRORNA 132; MICRORNA 134; MICRORNA 146; MICRORNA 146A; MICRORNA 155; MICRORNA 182; MICRORNA 34A; MICRORNA 9; MIRAVIRSEN; UNCLASSIFIED DRUG; OLIGONUCLEOTIDE;

EID: 84959243948     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.11.021     Document Type: Review
Times cited : (37)

References (95)
  • 1
    • 84901004299 scopus 로고    scopus 로고
    • The rise of regulatory RNA
    • K.V. Morris, and J.S. Mattick The rise of regulatory RNA Nat. Rev. Genet. 15 2014 423 437 10.1038/nrg3722
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 423-437
    • Morris, K.V.1    Mattick, J.S.2
  • 2
    • 84959254208 scopus 로고    scopus 로고
    • mirBase, miRBase blog
    • mirBase, miRBase blog, http://www.mirbase.org (2015).
    • (2015)
  • 3
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • M.S. Ebert, and P.A. Sharp Roles for microRNAs in conferring robustness to biological processes Cell 149 2012 515 524 10.1016/j.cell.2012.04.005
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 4
    • 84905503012 scopus 로고    scopus 로고
    • Therapeutic targeting of microRNAs: Current status and future challenges
    • Z. Li, and T.M. Rana Therapeutic targeting of microRNAs: current status and future challenges Nat. Rev. Drug Discov. 13 2014 622 638 10.1038/nrd4359
    • (2014) Nat. Rev. Drug Discov. , vol.13 , pp. 622-638
    • Li, Z.1    Rana, T.M.2
  • 5
    • 84876939170 scopus 로고    scopus 로고
    • The long and short of microRNA
    • L.A. Yates, C.J. Norbury, and R.J. Gilbert The long and short of microRNA Cell 153 2013 516 519 10.1016/j.cell.2013.04.003
    • (2013) Cell , vol.153 , pp. 516-519
    • Yates, L.A.1    Norbury, C.J.2    Gilbert, R.J.3
  • 6
    • 84904985459 scopus 로고    scopus 로고
    • Regulation of microRNA biogenesis
    • M. Ha, and V.N. Kim Regulation of microRNA biogenesis Nat. Rev. Mol. Cell Biol. 15 2014 509 524 10.1038/nrm3838
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , pp. 509-524
    • Ha, M.1    Kim, V.N.2
  • 7
    • 84879414849 scopus 로고    scopus 로고
    • Argonaute proteins: Functional insights and emerging roles
    • G. Meister Argonaute proteins: functional insights and emerging roles Nat. Rev. Genet. 14 2013 447 459 10.1038/nrg3462
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 447-459
    • Meister, G.1
  • 8
    • 84861866572 scopus 로고    scopus 로고
    • The mechanics of miRNA-mediated gene silencing: A look under the hood of miRISC
    • M.R. Fabian, and N. Sonenberg The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC Nat. Struct. Mol. Biol. 19 2012 586 593 10.1038/nsmb.2296
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 586-593
    • Fabian, M.R.1    Sonenberg, N.2
  • 9
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • J. Krol, I. Loedige, and W. Filipowicz The widespread regulation of microRNA biogenesis, function and decay Nat. Rev. Genet. 2010 10.1038/nrg2843
    • (2010) Nat. Rev. Genet.
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 10
  • 11
    • 84864126183 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
    • I.A. Qureshi, and M.F. Mehler Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease Nat. Rev. Neurosci. 13 2012 528 541 10.1038/nrn3234
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 528-541
    • Qureshi, I.A.1    Mehler, M.F.2
  • 12
    • 84886252113 scopus 로고    scopus 로고
    • RNA in unexpected places: Long non-coding RNA functions in diverse cellular contexts
    • S. Geisler, and J. Coller RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts Nat. Rev. Mol. Cell Biol. 14 2013 699 712 10.1038/nrm3679
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 699-712
    • Geisler, S.1    Coller, J.2
  • 13
    • 33847698971 scopus 로고    scopus 로고
    • The relationship between non-protein-coding DNA and eukaryotic complexity
    • R.J. Taft, M. Pheasant, and J.S. Mattick The relationship between non-protein-coding DNA and eukaryotic complexity BioEssay 29 2007 288 299 10.1002/bies.20544
    • (2007) BioEssay , vol.29 , pp. 288-299
    • Taft, R.J.1    Pheasant, M.2    Mattick, J.S.3
  • 14
    • 78650860741 scopus 로고    scopus 로고
    • Systematic analysis of human microRNA divergence based on evolutionary emergence
    • Q.H. Wang, M. Zhou, J. Sun, S.W. Ning, Y. Li, L. Chen, and et al. Systematic analysis of human microRNA divergence based on evolutionary emergence FEBS Lett. 585 2011 240 248 10.1016/j.febslet.2010.11.053
    • (2011) FEBS Lett. , vol.585 , pp. 240-248
    • Wang, Q.H.1    Zhou, M.2    Sun, J.3    Ning, S.W.4    Li, Y.5    Chen, L.6
  • 15
    • 84855175650 scopus 로고    scopus 로고
    • MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates
    • M. Somel, X. Liu, L. Tang, Z. Yan, H. Hu, S. Guo, and et al. MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates PLoS Biol. 9 2011 e1001214 10.1371/journal.pbio.1001214
    • (2011) PLoS Biol. , vol.9 , pp. e1001214
    • Somel, M.1    Liu, X.2    Tang, L.3    Yan, Z.4    Hu, H.5    Guo, S.6
  • 16
    • 84903593412 scopus 로고    scopus 로고
    • Identification of differentially expressed microRNAs across the developing human brain
    • M.N. Ziats, and O.M. Rennert Identification of differentially expressed microRNAs across the developing human brain Mol. Psychiatry 2013 1 5 10.1038/mp.2013.93
    • (2013) Mol. Psychiatry , pp. 1-5
    • Ziats, M.N.1    Rennert, O.M.2
  • 17
    • 79959463758 scopus 로고    scopus 로고
    • MicroRNA expression profiling reveals miRNA families regulating specific biological pathways in mouse frontal cortex and hippocampus
    • J. Juhila, T. Sipilä, K. Icay, D. Nicorici, P. Ellonen, A. Kallio, and et al. MicroRNA expression profiling reveals miRNA families regulating specific biological pathways in mouse frontal cortex and hippocampus PLoS One 6 2011 e21495 10.1371/journal.pone.0021495
    • (2011) PLoS One , vol.6 , pp. e21495
    • Juhila, J.1    Sipilä, T.2    Icay, K.3    Nicorici, D.4    Ellonen, P.5    Kallio, A.6
  • 18
    • 84877092851 scopus 로고    scopus 로고
    • Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes
    • A. Jovicic, R. Roshan, N. Moisoi, S. Pradervand, R. Moser, B. Pillai, and et al. Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes J. Neurosci. 33 2013 5127 5137 10.1523/JNEUROSCI.0600-12.2013
    • (2013) J. Neurosci. , vol.33 , pp. 5127-5137
    • Jovicic, A.1    Roshan, R.2    Moisoi, N.3    Pradervand, S.4    Moser, R.5    Pillai, B.6
  • 20
    • 84906095861 scopus 로고    scopus 로고
    • The RNA-centred view of the synapse: Non-coding RNAs and synaptic plasticity
    • N.R. Smalheiser The RNA-centred view of the synapse: non-coding RNAs and synaptic plasticity Philos. Trans. R. Soc. Lond. B Biol. Sci. 369 2014 10.1098/rstb.2013.0504
    • (2014) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.369
    • Smalheiser, N.R.1
  • 21
    • 80555125111 scopus 로고    scopus 로고
    • The cell biology of synaptic plasticity
    • V.M. Ho, J.-A. Lee, and K.C. Martin The cell biology of synaptic plasticity Science (New York, N.Y.) 334 2011 623 628 10.1126/science.1209236
    • (2011) Science (New York, N.Y.) , vol.334 , pp. 623-628
    • Ho, V.M.1    Lee, J.-A.2    Martin, K.C.3
  • 23
    • 84904685723 scopus 로고    scopus 로고
    • Translational control in synaptic plasticity and cognitive dysfunction
    • S.A. Buffington, W. Huang, and M. Costa-Mattioli Translational control in synaptic plasticity and cognitive dysfunction Annu. Rev. Neurosci. 37 2014 17 38
    • (2014) Annu. Rev. Neurosci. , vol.37 , pp. 17-38
    • Buffington, S.A.1    Huang, W.2    Costa-Mattioli, M.3
  • 24
    • 48449084118 scopus 로고    scopus 로고
    • Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
    • A. Marson, S.S. Levine, M.F. Cole, G.M. Frampton, T. Brambrink, S. Johnstone, and et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells Cell 134 2008 521 533 10.1016/j.cell.2008.07.020
    • (2008) Cell , vol.134 , pp. 521-533
    • Marson, A.1    Levine, S.S.2    Cole, M.F.3    Frampton, G.M.4    Brambrink, T.5    Johnstone, S.6
  • 25
    • 77950111923 scopus 로고    scopus 로고
    • Neuronal activity rapidly induces transcription of the CREB-regulated microRNA-132, in vivo
    • A.S. Nudelman, D.P. DiRocco, T.J. Lambert, M.G. Garelick, J. Le, N.M. Nathanson, and et al. Neuronal activity rapidly induces transcription of the CREB-regulated microRNA-132, in vivo Hippocampus 20 2010 492 498 10.1002/hipo.20646
    • (2010) Hippocampus , vol.20 , pp. 492-498
    • Nudelman, A.S.1    DiRocco, D.P.2    Lambert, T.J.3    Garelick, M.G.4    Le, J.5    Nathanson, N.M.6
  • 28
    • 28044439909 scopus 로고    scopus 로고
    • A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis
    • N. Vo, M.E. Klein, O. Varlamova, D.M. Keller, T. Yamamoto, R.H. Goodman, and et al. A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis PNAS 102 2005
    • (2005) PNAS , vol.102
    • Vo, N.1    Klein, M.E.2    Varlamova, O.3    Keller, D.M.4    Yamamoto, T.5    Goodman, R.H.6
  • 29
    • 84879504420 scopus 로고    scopus 로고
    • In vivo knockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning
    • R.Y. Wang, R.Z. Phang, P.H. Hsu, W.H. Wang, H.T. Huang, and I.Y. Liu In vivo knockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning Hippocampus 23 2013 625 633 10.1002/hipo.22123
    • (2013) Hippocampus , vol.23 , pp. 625-633
    • Wang, R.Y.1    Phang, R.Z.2    Hsu, P.H.3    Wang, W.H.4    Huang, H.T.5    Liu, I.Y.6
  • 30
    • 84866914733 scopus 로고    scopus 로고
    • MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex
    • H.L. Scott, F. Tamagnini, K.E. Narduzzo, J.L. Howarth, Y.B. Lee, L.F. Wong, and et al. MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex Eur. J. Neurosci. 36 2012 2941 2948 10.1111/j.1460-9568.2012.08220.x
    • (2012) Eur. J. Neurosci. , vol.36 , pp. 2941-2948
    • Scott, H.L.1    Tamagnini, F.2    Narduzzo, K.E.3    Howarth, J.L.4    Lee, Y.B.5    Wong, L.F.6
  • 31
    • 79956070442 scopus 로고    scopus 로고
    • MiR-132 mediates the integration of newborn neurons into the adult dentate gyrus
    • B.W. Luikart, A.L. Bensen, E.K. Washburn, J.V. Perederiy, K.G. Su, Y. Li, and et al. miR-132 mediates the integration of newborn neurons into the adult dentate gyrus PLoS One 6 2011 e19077 10.1371/journal.pone.0019077
    • (2011) PLoS One , vol.6 , pp. e19077
    • Luikart, B.W.1    Bensen, A.L.2    Washburn, E.K.3    Perederiy, J.V.4    Su, K.G.5    Li, Y.6
  • 33
    • 84876851786 scopus 로고    scopus 로고
    • MiR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity
    • J. Remenyi, M.W. van den Bosch, O. Palygin, R.B. Mistry, C. McKenzie, A. Macdonald, and et al. miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity PLoS One 8 2013 e62509 10.1371/journal.pone.0062509
    • (2013) PLoS One , vol.8 , pp. e62509
    • Remenyi, J.1    Van Den Bosch, M.W.2    Palygin, O.3    Mistry, R.B.4    McKenzie, C.5    Macdonald, A.6
  • 34
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specific microRNA regulates dendritic spine development
    • G.M. Schratt, F. Tuebing, E.A. Nigh, C.G. Kane, M.E. Sabatini, M. Kiebler, and et al. A brain-specific microRNA regulates dendritic spine development Nature 439 2006 283 289 10.1038/nature04367
    • (2006) Nature , vol.439 , pp. 283-289
    • Schratt, G.M.1    Tuebing, F.2    Nigh, E.A.3    Kane, C.G.4    Sabatini, M.E.5    Kiebler, M.6
  • 35
    • 77956185062 scopus 로고    scopus 로고
    • A novel pathway regulates memory and plasticity via SIRT1 and miR-134
    • J. Gao, W.-Y. Wang, Y.-W. Mao, J. Gräff, J.-S. Guan, L. Pan, and et al. A novel pathway regulates memory and plasticity via SIRT1 and miR-134 Nature 466 2010 1105 1109 10.1038/nature09271
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1    Wang, W.-Y.2    Mao, Y.-W.3    Gräff, J.4    Guan, J.-S.5    Pan, L.6
  • 37
    • 84907597799 scopus 로고    scopus 로고
    • Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling
    • B.G. Dias, J.V. Goodman, R. Ahluwalia, A.E. Easton, R. Andero, and K.J. Ressler Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling Neuron 83 2014 906 918 10.1016/j.neuron.2014.07.019
    • (2014) Neuron , vol.83 , pp. 906-918
    • Dias, B.G.1    Goodman, J.V.2    Ahluwalia, R.3    Easton, A.E.4    Andero, R.5    Ressler, K.J.6
  • 38
    • 80052265830 scopus 로고    scopus 로고
    • The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory
    • Q. Lin, W. Wei, C.M. Coelho, X. Li, D. Baker-Andresen, K. Dudley, and et al. The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory Nat. Neurosci. 14 2011 1115 1117 10.1038/nn.2891
    • (2011) Nat. Neurosci. , vol.14 , pp. 1115-1117
    • Lin, Q.1    Wei, W.2    Coelho, C.M.3    Li, X.4    Baker-Andresen, D.5    Dudley, K.6
  • 39
    • 80053938493 scopus 로고    scopus 로고
    • Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology
    • G. Lippi, J.R. Steinert, E.L. Marczylo, S. D'Oro, R. Fiore, I.D. Forsythe, and et al. Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology J. Cell Biol. 194 2011 889 904 10.1083/jcb.201103006
    • (2011) J. Cell Biol. , vol.194 , pp. 889-904
    • Lippi, G.1    Steinert, J.R.2    Marczylo, E.L.3    D'Oro, S.4    Fiore, R.5    Forsythe, I.D.6
  • 40
    • 84872716399 scopus 로고    scopus 로고
    • MicroRNA-182 regulates amygdala-dependent memory formation
    • E.M. Griggs, E.J. Young, G. Rumbaugh, and C.A. Miller MicroRNA-182 regulates amygdala-dependent memory formation J. Neurosci. 33 2013 1734 1740 10.1523/JNEUROSCI.2873-12.2013
    • (2013) J. Neurosci. , vol.33 , pp. 1734-1740
    • Griggs, E.M.1    Young, E.J.2    Rumbaugh, G.3    Miller, C.A.4
  • 41
  • 42
    • 43949124669 scopus 로고    scopus 로고
    • Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
    • K.L. Stark, B. Xu, A. Bagchi, W.S. Lai, H. Liu, R. Hsu, and et al. Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model Nat. Genet. 40 2008 751 760 10.1038/ng.138
    • (2008) Nat. Genet. , vol.40 , pp. 751-760
    • Stark, K.L.1    Xu, B.2    Bagchi, A.3    Lai, W.S.4    Liu, H.5    Hsu, R.6
  • 43
    • 84894182409 scopus 로고    scopus 로고
    • Association of impulsivity and polymorphic microRNA-641 target sites in the SNAP-25 gene
    • N. Nemeth, R. Kovacs-Nagy, A. Szekely, M. Sasvari-Szekely, and Z. Ronai Association of impulsivity and polymorphic microRNA-641 target sites in the SNAP-25 gene PLoS One 8 2013 e84207 10.1371/journal.pone.0084207
    • (2013) PLoS One , vol.8 , pp. e84207
    • Nemeth, N.1    Kovacs-Nagy, R.2    Szekely, A.3    Sasvari-Szekely, M.4    Ronai, Z.5
  • 44
    • 80053447556 scopus 로고    scopus 로고
    • Neuronal activity regulates hippocampal miRNA expression
    • S.M. Eacker, M.J. Keuss, E. Berezikov, V.L. Dawson, and T.M. Dawson Neuronal activity regulates hippocampal miRNA expression PLoS One 6 2011 e25068 10.1371/journal.pone.0025068
    • (2011) PLoS One , vol.6 , pp. e25068
    • Eacker, S.M.1    Keuss, M.J.2    Berezikov, E.3    Dawson, V.L.4    Dawson, T.M.5
  • 45
    • 77952479722 scopus 로고    scopus 로고
    • Characterizing light-regulated retinal micrornas reveals rapid turnover as a common property of neuronal microRNAs
    • J. Krol, V. Busskamp, I. Markiewicz, M.B. Stadler, S. Ribi, J. Richter, and et al. Characterizing light-regulated retinal micrornas reveals rapid turnover as a common property of neuronal microRNAs Cell 2010 618 631 10.1016/j.cell.2010.03.039
    • (2010) Cell , pp. 618-631
    • Krol, J.1    Busskamp, V.2    Markiewicz, I.3    Stadler, M.B.4    Ribi, S.5    Richter, J.6
  • 46
    • 76949084430 scopus 로고    scopus 로고
    • Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo
    • K. Wibrand, D. Panja, A. Tiron, M.L. Ofte, K.-O. Skaftnesmo, C.S. Lee, and et al. Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo Eur. J. Neurosci. 31 2010 636 645 10.1111/j.1460-9568.2010.07112.x
    • (2010) Eur. J. Neurosci. , vol.31 , pp. 636-645
    • Wibrand, K.1    Panja, D.2    Tiron, A.3    Ofte, M.L.4    Skaftnesmo, K.-O.5    Lee, C.S.6
  • 47
    • 84927646759 scopus 로고    scopus 로고
    • MiR-26a and miR-384-5p are required for LTP maintenance and spine enlargement
    • Q.H. Gu, D. Yu, Z. Hu, X. Liu, Y. Yang, Y. Luo, and et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement Nat. Commun. 6 2015 6789 10.1038/ncomms7789
    • (2015) Nat. Commun. , vol.6 , pp. 6789
    • Gu, Q.H.1    Yu, D.2    Hu, Z.3    Liu, X.4    Yang, Y.5    Luo, Y.6
  • 48
    • 84859748623 scopus 로고    scopus 로고
    • An activity-regulated microRNA, miR-188, controls dendritic plasticity and synaptic transmission by downregulating neuropilin-2
    • K. Lee, J.-H. Kim, O.-B. Kwon, K. An, J. Ryu, K. Cho, and et al. An activity-regulated microRNA, miR-188, controls dendritic plasticity and synaptic transmission by downregulating neuropilin-2 J. Neurosci. 32 2012 5678 5687 10.1523/JNEUROSCI.6471-11.2012
    • (2012) J. Neurosci. , vol.32 , pp. 5678-5687
    • Lee, K.1    Kim, J.-H.2    Kwon, O.-B.3    An, K.4    Ryu, J.5    Cho, K.6
  • 49
    • 84894378475 scopus 로고    scopus 로고
    • MiR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression
    • Z. Hu, D. Yu, Q.-h. Gu, Y. Yang, K. Tu, J. Zhu, and et al. miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression Nat. Commun. 5 2014 3263 10.1038/ncomms4263
    • (2014) Nat. Commun. , vol.5 , pp. 3263
    • Hu, Z.1    Yu, D.2    Gu, Q.-H.3    Yang, Y.4    Tu, K.5    Zhu, J.6
  • 50
    • 80052625713 scopus 로고    scopus 로고
    • NMDA mediated contextual conditioning changes miRNA expression
    • M.J. Kye, P. Neveu, Y.-S. Lee, M. Zhou, J.A. Steen, M. Sahin, and et al. NMDA mediated contextual conditioning changes miRNA expression PLoS One 6 2011 e24682 10.1371/journal.pone.0024682
    • (2011) PLoS One , vol.6 , pp. e24682
    • Kye, M.J.1    Neveu, P.2    Lee, Y.-S.3    Zhou, M.4    Steen, J.A.5    Sahin, M.6
  • 52
    • 84877992935 scopus 로고    scopus 로고
    • Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p
    • Y.-L. Chen, and C.-K.J. Shen Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p J. Neurosci. 33 2013 9013 9020 10.1523/JNEUROSCI.5210-12.2013
    • (2013) J. Neurosci. , vol.33 , pp. 9013-9020
    • Chen, Y.-L.1    Shen, C.-K.J.2
  • 53
    • 77950669026 scopus 로고    scopus 로고
    • MicroRNA-92 modulates K(+) Cl(-) co-transporter KCC2 expression in cerebellar granule neurons
    • C. Barbato, F. Ruberti, M. Pieri, E. Vilardo, M. Costanzo, M.T. Ciotti, and et al. MicroRNA-92 modulates K(+) Cl(-) co-transporter KCC2 expression in cerebellar granule neurons J. Neurochem. 113 2010 591 600 10.1111/j.1471-4159.2009.06560.x
    • (2010) J. Neurochem. , vol.113 , pp. 591-600
    • Barbato, C.1    Ruberti, F.2    Pieri, M.3    Vilardo, E.4    Costanzo, M.5    Ciotti, M.T.6
  • 54
    • 61849157257 scopus 로고    scopus 로고
    • Alzheimer's disease
    • A. Burns, and S. Iliffe Alzheimer's disease BMJ 338 2009 b158
    • (2009) BMJ , vol.338 , pp. b158
    • Burns, A.1    Iliffe, S.2
  • 55
    • 58849143335 scopus 로고    scopus 로고
    • Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: Relationship and links in Alzheimer's disease
    • 8486T72647013647 [pii]
    • H.C. Huang, and Z.F. Jiang Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease J. Alzheimer's Dis. 16 2009 15 27 10.3233/JAD-2009-0960 8486T72647013647 [pii]
    • (2009) J. Alzheimer's Dis. , vol.16 , pp. 15-27
    • Huang, H.C.1    Jiang, Z.F.2
  • 56
    • 84905406846 scopus 로고    scopus 로고
    • MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease
    • J. Banzhaf-Strathmann, E. Benito, S. May, T. Arzberger, S. Tahirovic, H. Kretzschmar, and et al. MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease EMBO J. 33 2014 1667 1680 10.15252/embj.201387576
    • (2014) EMBO J. , vol.33 , pp. 1667-1680
    • Banzhaf-Strathmann, J.1    Benito, E.2    May, S.3    Arzberger, T.4    Tahirovic, S.5    Kretzschmar, H.6
  • 57
    • 84884959481 scopus 로고    scopus 로고
    • Alteration of the microRNA network during the progression of Alzheimer's disease
    • P. Lau, K. Bossers, R. Janky, E. Salta, C.S. Frigerio, S. Barbash, and et al. Alteration of the microRNA network during the progression of Alzheimer's disease EMBO Mol. Med. 5 2013 1613 1634 10.1002/emmm.201201974
    • (2013) EMBO Mol. Med. , vol.5 , pp. 1613-1634
    • Lau, P.1    Bossers, K.2    Janky, R.3    Salta, E.4    Frigerio, C.S.5    Barbash, S.6
  • 58
    • 84860369464 scopus 로고    scopus 로고
    • Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease
    • H. Geekiyanage, G.A. Jicha, P.T. Nelson, and C. Chan Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease Exp. Neurol. 235 2012 491 496 10.1016/j.expneurol.2011.11.026
    • (2012) Exp. Neurol. , vol.235 , pp. 491-496
    • Geekiyanage, H.1    Jicha, G.A.2    Nelson, P.T.3    Chan, C.4
  • 59
    • 84877117884 scopus 로고    scopus 로고
    • A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls
    • S.S. Hebert, W.X. Wang, Q. Zhu, and P.T. Nelson A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls J. Alzheimer's Dis. 35 2013 335 348 10.3233/JAD-122350
    • (2013) J. Alzheimer's Dis. , vol.35 , pp. 335-348
    • Hebert, S.S.1    Wang, W.X.2    Zhu, Q.3    Nelson, P.T.4
  • 61
    • 84961288011 scopus 로고    scopus 로고
    • Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia
    • E. Gascon, K. Lynch, H. Ruan, S. Almeida, J.M. Verheyden, W.W. Seeley, and et al. Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia Nat. Med. 20 2014 1444 1451 10.1038/nm.3717
    • (2014) Nat. Med. , vol.20 , pp. 1444-1451
    • Gascon, E.1    Lynch, K.2    Ruan, H.3    Almeida, S.4    Verheyden, J.M.5    Seeley, W.W.6
  • 62
    • 84874330748 scopus 로고    scopus 로고
    • A way forward for research on biomarkers for psychiatric disorders
    • P. Boksa A way forward for research on biomarkers for psychiatric disorders J. Psychiatry Neurosci. 38 2013 55 75 10.1503/jpn.130018
    • (2013) J. Psychiatry Neurosci. , vol.38 , pp. 55-75
    • Boksa, P.1
  • 63
    • 84888320145 scopus 로고    scopus 로고
    • Circulating microRNAs in Alzheimer's disease: The search for novel biomarkers
    • V. Dorval, P.T. Nelson, and S.S. Hebert Circulating microRNAs in Alzheimer's disease: the search for novel biomarkers Front. Mol. Neurosci. 6 2013 24 10.3389/fnmol.2013.00024
    • (2013) Front. Mol. Neurosci. , vol.6 , pp. 24
    • Dorval, V.1    Nelson, P.T.2    Hebert, S.S.3
  • 64
    • 84867334962 scopus 로고    scopus 로고
    • Cell-to-cell miRNA transfer: From body homeostasis to therapy
    • R.S. Redis, S. Calin, Y. Yang, M.J. You, and G.A. Calin Cell-to-cell miRNA transfer: from body homeostasis to therapy Pharmacol. Ther. 136 2012 169 174 10.1016/j.pharmthera.2012.08.003
    • (2012) Pharmacol. Ther. , vol.136 , pp. 169-174
    • Redis, R.S.1    Calin, S.2    Yang, Y.3    You, M.J.4    Calin, G.A.5
  • 65
    • 79953301730 scopus 로고    scopus 로고
    • MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
    • K.C. Vickers, B.T. Palmisano, B.M. Shoucri, R.D. Shamburek, and A.T. Remaley MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins Nat. Cell Biol. 13 2011 423 433 10.1038/ncb2210
    • (2011) Nat. Cell Biol. , vol.13 , pp. 423-433
    • Vickers, K.C.1    Palmisano, B.T.2    Shoucri, B.M.3    Shamburek, R.D.4    Remaley, A.T.5
  • 66
    • 77952920881 scopus 로고    scopus 로고
    • Secretory mechanisms and intercellular transfer of microRNAs in living cells
    • N. Kosaka, H. Iguchi, Y. Yoshioka, F. Takeshita, Y. Matsuki, and T. Ochiya Secretory mechanisms and intercellular transfer of microRNAs in living cells J. Biol. Chem. 285 2010 17442 17452 10.1074/jbc.m110.107821
    • (2010) J. Biol. Chem. , vol.285 , pp. 17442-17452
    • Kosaka, N.1    Iguchi, H.2    Yoshioka, Y.3    Takeshita, F.4    Matsuki, Y.5    Ochiya, T.6
  • 67
    • 84940730294 scopus 로고    scopus 로고
    • A differentially expressed set of micrornas in cerebro-spinal fluid (CSF) can diagnose CNS malignancies
    • A. Drusco, A. Bottoni, A. Lagana, M. Acunzo, M. Fassan, L. Cascione, and et al. A differentially expressed set of micrornas in cerebro-spinal fluid (CSF) can diagnose CNS malignancies Oncotarget 6 25 2015 20829 20839
    • (2015) Oncotarget , vol.6 , Issue.25 , pp. 20829-20839
    • Drusco, A.1    Bottoni, A.2    Lagana, A.3    Acunzo, M.4    Fassan, M.5    Cascione, L.6
  • 68
    • 73949091031 scopus 로고    scopus 로고
    • Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures
    • D.Z. Liu, Y. Tian, B.P. Ander, H. Xu, B.S. Stamova, X. Zhan, and et al. Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures J. Cereb. Blood Flow Metab. 30 2010 92 101 10.1038/jcbfm.2009.186
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 92-101
    • Liu, D.Z.1    Tian, Y.2    Ander, B.P.3    Xu, H.4    Stamova, B.S.5    Zhan, X.6
  • 69
    • 84885040378 scopus 로고    scopus 로고
    • Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies
    • K.S. Sheinerman, and S.R. Umansky Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies Front. Cell. Neurosci. 7 2013 150 10.3389/fncel.2013.00150
    • (2013) Front. Cell. Neurosci. , vol.7 , pp. 150
    • Sheinerman, K.S.1    Umansky, S.R.2
  • 70
    • 84896970969 scopus 로고    scopus 로고
    • Micro spies from the brain to the periphery: New clues from studies on microRNAs in neuropsychiatric disorders
    • E. Maffioletti, D. Tardito, M. Gennarelli, and L. Bocchio-Chiavetto Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders Front. Cell. Neurosci. 8 2014 75 10.3389/fncel.2014.00075
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 75
    • Maffioletti, E.1    Tardito, D.2    Gennarelli, M.3    Bocchio-Chiavetto, L.4
  • 71
    • 84864352823 scopus 로고    scopus 로고
    • Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells
    • E. Gardiner, N.J. Beveridge, J.Q. Wu, V. Carr, R.J. Scott, P.A. Tooney, and et al. Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells Mol. Psychiatry 17 2012 827 840 10.1038/mp.2011.78
    • (2012) Mol. Psychiatry , vol.17 , pp. 827-840
    • Gardiner, E.1    Beveridge, N.J.2    Wu, J.Q.3    Carr, V.4    Scott, R.J.5    Tooney, P.A.6
  • 72
    • 84901326342 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly
    • B. Arosio, C. D'Addario, C. Gussago, M. Casati, E. Tedone, E. Ferri, and et al. Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly BioMed Res. Int. 2014 2014 169203 10.1155/2014/169203
    • (2014) BioMed Res. Int. , vol.2014 , pp. 169203
    • Arosio, B.1    D'Addario, C.2    Gussago, C.3    Casati, M.4    Tedone, E.5    Ferri, E.6
  • 73
    • 84871695724 scopus 로고    scopus 로고
    • MicroRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF)
    • P.N. Alexandrov, P. Dua, J.M. Hill, S. Bhattacharjee, Y. Zhao, and W.J. Lukiw MicroRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF) Int. J. Biochem. Mol. Biol. 3 2012 365 373
    • (2012) Int. J. Biochem. Mol. Biol. , vol.3 , pp. 365-373
    • Alexandrov, P.N.1    Dua, P.2    Hill, J.M.3    Bhattacharjee, S.4    Zhao, Y.5    Lukiw, W.J.6
  • 74
    • 84930677807 scopus 로고    scopus 로고
    • MicroRNA profiling of CSF reveals potential biomarkers to detect Alzheimer's disease
    • J. Denk, K. Boelmans, C. Siegismund, D. Lassner, S. Arlt, and H. Jahn MicroRNA profiling of CSF reveals potential biomarkers to detect Alzheimer's disease PLoS One 10 2015 e0126423 10.1371/journal.pone.0126423
    • (2015) PLoS One , vol.10 , pp. e0126423
    • Denk, J.1    Boelmans, K.2    Siegismund, C.3    Lassner, D.4    Arlt, S.5    Jahn, H.6
  • 77
    • 84891525727 scopus 로고    scopus 로고
    • Plasma microRNA biomarkers for detection of mild cognitive impairment: Biomarker validation study
    • K.S. Sheinerman, V.G. Tsivinsky, L. Abdullah, F. Crawford, and S.R. Umansky Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study Aging (Albany, NY) 5 2013 925 938
    • (2013) Aging (Albany, NY) , vol.5 , pp. 925-938
    • Sheinerman, K.S.1    Tsivinsky, V.G.2    Abdullah, L.3    Crawford, F.4    Umansky, S.R.5
  • 78
    • 84942549950 scopus 로고    scopus 로고
    • Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment
    • L. Cheng, J.D. Doecke, R.A. Sharples, V.L. Villemagne, C.J. Fowler, A. Rembach, and et al. Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment Mol. Psychiatry 2014 10.1038/mp.2014.127
    • (2014) Mol. Psychiatry
    • Cheng, L.1    Doecke, J.D.2    Sharples, R.A.3    Villemagne, V.L.4    Fowler, C.J.5    Rembach, A.6
  • 79
    • 84885178226 scopus 로고    scopus 로고
    • MicroRNAs in Alzheimer's disease: Differential expression in hippocampus and cell-free cerebrospinal fluid
    • M. Muller, H.B. Kuiperij, J.A. Claassen, B. Kusters, and M.M. Verbeek MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid Neurobiol. Aging 35 2014 152 158 10.1016/j.neurobiolaging.2013.07.005
    • (2014) Neurobiol. Aging , vol.35 , pp. 152-158
    • Muller, M.1    Kuiperij, H.B.2    Claassen, J.A.3    Kusters, B.4    Verbeek, M.M.5
  • 80
    • 84893946623 scopus 로고    scopus 로고
    • MicroRNAs in plasma and cerebrospinal fluid as potential markers for Alzheimer's disease
    • T. Kiko, K. Nakagawa, T. Tsuduki, K. Furukawa, H. Arai, and T. Miyazawa MicroRNAs in plasma and cerebrospinal fluid as potential markers for Alzheimer's disease J. Alzheimer's Dis. 39 2014 253 259 10.3233/jad-130932
    • (2014) J. Alzheimer's Dis. , vol.39 , pp. 253-259
    • Kiko, T.1    Nakagawa, K.2    Tsuduki, T.3    Furukawa, K.4    Arai, H.5    Miyazawa, T.6
  • 82
    • 84928891380 scopus 로고    scopus 로고
    • Identification of differential microRNAs in cerebrospinal fluid and serum of patients with major depressive disorder
    • Y. Wan, Y. Liu, X. Wang, J. Wu, K. Liu, J. Zhou, and et al. Identification of differential microRNAs in cerebrospinal fluid and serum of patients with major depressive disorder PLoS One 10 2015 e0121975 10.1371/journal.pone.0121975
    • (2015) PLoS One , vol.10 , pp. e0121975
    • Wan, Y.1    Liu, Y.2    Wang, X.3    Wu, J.4    Liu, K.5    Zhou, J.6
  • 83
    • 84922973531 scopus 로고    scopus 로고
    • Aberrant microRNA expression in peripheral plasma and mononuclear cells as specific blood-based biomarkers in schizophrenia patients
    • X.Y. Sun, J. Lu, L. Zhang, H.T. Song, L. Zhao, H.M. Fan, and et al. Aberrant microRNA expression in peripheral plasma and mononuclear cells as specific blood-based biomarkers in schizophrenia patients J. Clin. Neurosci. 22 2015 570 574 10.1016/j.jocn.2014.08.018
    • (2015) J. Clin. Neurosci. , vol.22 , pp. 570-574
    • Sun, X.Y.1    Lu, J.2    Zhang, L.3    Song, H.T.4    Zhao, L.5    Fan, H.M.6
  • 84
    • 79959663462 scopus 로고    scopus 로고
    • MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia
    • C.Y. Lai, S.L. Yu, M.H. Hsieh, C.H. Chen, H.Y. Chen, C.C. Wen, and et al. MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia PLoS One 6 2011 e21635 10.1371/journal.pone.0021635
    • (2011) PLoS One , vol.6 , pp. e21635
    • Lai, C.Y.1    Yu, S.L.2    Hsieh, M.H.3    Chen, C.H.4    Chen, H.Y.5    Wen, C.C.6
  • 86
    • 84906514233 scopus 로고    scopus 로고
    • Evaluation of several micro RNA (miRNA) levels in children and adolescents with attention deficit hyperactivity disorder
    • H. Kandemir, M.E. Erdal, S. Selek, O.I. Ay, I.F. Karababa, S.B. Kandemir, and et al. Evaluation of several micro RNA (miRNA) levels in children and adolescents with attention deficit hyperactivity disorder Neurosci. Lett. 580 2014 158 162 10.1016/j.neulet.2014.07.060
    • (2014) Neurosci. Lett. , vol.580 , pp. 158-162
    • Kandemir, H.1    Erdal, M.E.2    Selek, S.3    Ay, O.I.4    Karababa, I.F.5    Kandemir, S.B.6
  • 88
    • 84908221196 scopus 로고    scopus 로고
    • Drug target miRNAs: Chances and challenges
    • M.F. Schmidt Drug target miRNAs: chances and challenges Trends Biotechnol. 32 2014 578 585 10.1016/j.tibtech.2014.09.002
    • (2014) Trends Biotechnol. , vol.32 , pp. 578-585
    • Schmidt, M.F.1
  • 89
    • 84959180993 scopus 로고    scopus 로고
    • miRNA-Therapeutics, miRNA Therapeutics
    • miRNA-Therapeutics, miRNA Therapeutics, http://www.mirnatherapeutics.com/pipeline/mirna-MRX34 (2015).
    • (2015)
  • 90
    • 84869219338 scopus 로고    scopus 로고
    • MiR-34 - A microRNA replacement therapy is headed to the clinic
    • A.G. Bader miR-34 - a microRNA replacement therapy is headed to the clinic Front. Genet. 3 2012 120 10.3389/fgene.2012.00120
    • (2012) Front. Genet. , vol.3 , pp. 120
    • Bader, A.G.1
  • 91
    • 84887143967 scopus 로고    scopus 로고
    • Nanoparticles as drug delivery systems in cancer medicine: Emphasis on RNAi-containing nanoliposomes
    • M.R. Diaz, and P.E. Vivas-Mejia Nanoparticles as drug delivery systems in cancer medicine: emphasis on RNAi-containing nanoliposomes Pharmaceuticals (Basel, Switzerland) 6 2013 1361 1380 10.3390/ph6111361
    • (2013) Pharmaceuticals (Basel, Switzerland) , vol.6 , pp. 1361-1380
    • Diaz, M.R.1    Vivas-Mejia, P.E.2
  • 92
    • 84938496867 scopus 로고    scopus 로고
    • A significant metabolic and radiological response after a novel targeted microRNA-based treatment approach in malignant pleural mesothelioma
    • S.C. Kao, M. Fulham, K. Wong, W. Cooper, H. Brahmbhatt, J. MacDiarmid, and et al. A significant metabolic and radiological response after a novel targeted microRNA-based treatment approach in malignant pleural mesothelioma Am. J. Respir. Crit. Care Med. 191 2015 1467 1469 10.1164/rccm.201503-0461le
    • (2015) Am. J. Respir. Crit. Care Med. , vol.191 , pp. 1467-1469
    • Kao, S.C.1    Fulham, M.2    Wong, K.3    Cooper, W.4    Brahmbhatt, H.5    MacDiarmid, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.