MicroRNA-92 modulates K(+) Cl(-) co-transporter KCC2 expression in cerebellar granule neurons

Journal of Neurochemistry

Volumn 113, Issue 3, 2010, Pages 591-600

  Barbato, Christian ^a,b   Ruberti, Francesca ^b   Pieri, Massimo ^c,d   Vilardo, Elisa ^b   Costanzo, Manuela ^b   Ciotti, Maria Teresa ^b   Zona, Cristina ^c,d   Cogoni, Carlo ^a,e  

^a EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Cerebellar granule neurons; Development; GABA; KCC2; MicroRNA

Indexed keywords

4 AMINOBUTYRIC ACID; CARRIER PROTEIN; CHLORIDE ION; MICRORNA; POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CELL MATURATION; CHLORIDE CURRENT; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GRANULE CELL; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IN VITRO STUDY; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; RAT; UPREGULATION;

3' UNTRANSLATED REGIONS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; CEREBELLUM; CYTOPLASMIC GRANULES; ELECTROPHYSIOLOGY; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC VECTORS; LENTIVIRUS; LUCIFERASES; MICRORNAS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; SYMPORTERS;

RATTUS;

EID: 77950669026     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06560.x     Document Type: Article

References (33)

1. Akaike N. (1996) Gramicidin perforated patch recording and intracellular chloride activity in excitable cells. Prog. Biophys. Mol. Biol. 65, 251 264. (Pubitemid 27164028)
2. Ashraf S. I. Kunes S. (2006) A trace of silence: memory and microRNA at the synapse. Curr. Opin. Neurobiol. 16, 535 539. (Pubitemid 44466395)
3. Barbato C., Giorgi C., Catalanotto C. Cogoni C. (2008) Thinking about RNA? MicroRNAs in the brain. Mamm. Genome 19, 541 551.
4. Bartel D. P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281 297.
5. Bartel D. P. (2009) MicroRNAs: target recognition and regulatory functions. Cell 136, 215 233.
6. Blaesse P., Airaksinen M. S., Rivera C. Kaila K. (2009) Cation-chloride cotransporters and neuronal function. Neuron 61, 820 838.
7. Borodinsky L. N., O'Leary D., Neale J. H., Vicini S., Coso O. A. Fiszman M. L. (2003) GABA-induced neurite outgrowth of cerebellar granule cells is mediated by GABA(A) receptor activation, calcium influx and CaMKII and erk1/2 pathways. J. Neurochem. 84, 1411 1420. (Pubitemid 36343607)
8. Bortone D. Polleux F. (2009) KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner. Neuron. 62, 53 71.
9. Cancedda L., Fiumelli H., Chen K. Poo M. M. (2007) Excitatory GABA action is essential for morphological maturation of cortical neurons in vivo. J. Neurosci. 27, 5224 5235. (Pubitemid 46741781)
10. Dull T., Zufferey R., Kelly M., Mandel R. J., Nguyen M., Trono D. Naldini L. (1998) A third-generation lentivirus vector with a conditional packaging system. J. Virol. 72, 8463 8471. (Pubitemid 28471781)
11. Ebert M. S., Neilson J. R. Sharp P. A. (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods. 4, 721 726. (Pubitemid 47338166)
12. Gentner B., Schira G., Giustacchini A., Amendola M., Brown B. D., Ponzoni M. Naldini L. (2009) Stable knockdown of microRNA in vivo by lentiviral vectors. Nat. Methods. 6, 63 66.
13. Griffiths-Jones S. (2006) miRBase: the microRNA sequence database. Methods Mol. Biol. 342, 129 138.
14. Grimson A., Farh K. K., Johnston W. K., Garrett-Engele P., Lim L. P. Bartel D. P. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 27, 91 105. (Pubitemid 46991392)
15. He L., Thomson J. M., Hemann M. T. et al. (2005) A microRNA polycistron as a potential human oncogene. Nature 435, 828 833. (Pubitemid 40839734)
16. Kissler S., Stern P., Takahashi K., Hunter K., Peterson L. B. Wicker L. S. (2006) In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes. Nat. Genet. 38, 479 483.
17. Kosik K. S. (2006) The neuronal microRNA system. Nat. Rev. Neurosci. 7, 911 920.
18. Krek A., Grün D., Poy M. N. et al. (2005) Combinatorial microRNA target predictions. Nat. Genet. 37, 495 500. (Pubitemid 40617277)
19. Kügler S., Meyn L., Holzmüller H., Gerhardt E., Isenmann S., Schultz J. B. Bähr M. (2001) Neuron-specific expression of therapeutic proteins: evaluation of different cellular promoters in recombinant adenoviral vectors. Mol. Cell. Neurosci. 17, 78 96. (Pubitemid 32113540)
20. Kyrozis A. Reichling D. B. (1995) Perforated-patch recording with gramicidin avoids artifactual changes in intracellular chloride concentration. J. Neurosci. Methods 57, 27 35.
21. Lagos-Quintana M., Rauhut R., Yalcin A., Meyer J., Lendeckel W. Tuschl T. (2002) Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12, 735 739. (Pubitemid 34455427)
22. Lewis B. P., Burge C. B. Bartel D. P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15 20.
23. Lu J., Karadsheh M. Delpire E. (1999) Developmental regulation of the neuronal-specific isoform of K-Cl (-) cotransporter KCC2 in postnatal rat brains. J. Neurobiol. 39, 558 568. (Pubitemid 29260776)
24. Mikawa S., Wang C., Shu F., Wang T., Fukuda A. Sato K. (2002) Developmental changes in KCC1, KCC2 and NKCC1 mRNAs in the rat cerebellum. Brain Res. Dev. Brain Res. 136, 93 100. (Pubitemid 34718115)
25. Nakanishi S. Okazawa M. (2006) Membrane potential-regulated Ca2+ signalling in development and maturation of mammalian cerebellar granule cells. J. Physiol. 575, 389 395. (Pubitemid 44270169)
26. Ruberti F. Dotti C. G. (2000) Involvement of the proximal C terminus of the AMPA receptor subunit GluR1 in dendritic sorting. J. Neurosci. 20, RC78.
27. Schratt G. (2009) Fine-tuning neural gene expression with microRNAs. Curr. Opin. Neurobiol. 19, 213 219.
28. Takayama C. Inoue Y. (2006) Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation. Neuroscience 143, 757 767. (Pubitemid 44751369)
29. Uvarov P., Ludwig A., Markkanen M., Rivera C. Airaksinen M. S. (2006) Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4. J. Neurosci. 26, 13463 13473. (Pubitemid 46026478)
30. Uziel T., Karginov F. V., Xie S. et al. (2009) The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma. Proc. Natl Acad. Sci. USA 106, 2812 2817.
31. Wang X. El Naqa I. M. (2008) Prediction of both conserved and nonconserved microRNA targets in animals. Bioinformatics 24, 325 332. (Pubitemid 351189007)
32. Yekta S., Shih I. H. Bartel D. P. (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science 304, 594 596. (Pubitemid 38541919)
33. Yeo M., Berglund K., Augustine G. Liedtke W. (2009) Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride. J. Neurosci. 29, 14652 14662.