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Volumn 20, Issue 12, 2014, Pages 1444-1451

Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia

(15)  Gascon, Eduardo a   Lynch, Kelleen a   Ruan, Hongyu b   Almeida, Sandra a,i   Verheyden, Jamie M c,f   Seeley, William W d   Dickson, Dennis W e   Petrucelli, Leonard e   Sun, Danqiong c,g   Jiao, Jian c,h   Zhou, Hongru a   Jakovcevski, Mira a   Akbarian, Schahram a,f   Yao, Wei Dong b,f,j   Gao, Fen Biao a  


Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; CALCIUM; CHMP2B PROTEIN, MOUSE; ESCRT PROTEIN; MICRORNA; MIRN124 MICRORNA, MOUSE; NERVE PROTEIN;

EID: 84961288011     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3717     Document Type: Article
Times cited : (161)

References (62)
  • 1
    • 84872729641 scopus 로고    scopus 로고
    • Parkinson's disease and parkinsonism: Neuropathology
    • Dickson, D. W. Parkinson's disease and parkinsonism: neuropathology. Cold Spring Harb. Perspect. Med. 2, a009258 (2012).
    • (2012) Cold Spring Harb. Perspect. Med. , vol.2 , pp. a009258
    • Dickson, D.W.1
  • 2
    • 84875245319 scopus 로고    scopus 로고
    • Changes in cognition and behaviour in amyotrophic lateral sclerosis: Nature of impairment and implications for assessment
    • Goldstein, L. H., Abrahams, S. Changes in cognition and behaviour in amyotrophic lateral sclerosis: nature of impairment and implications for assessment. Lancet Neurol. 12, 368-380 (2013).
    • (2013) Lancet Neurol. , vol.12 , pp. 368-380
    • Goldstein, L.H.1    Abrahams, S.2
  • 7
    • 84881490873 scopus 로고    scopus 로고
    • Converging mechanisms in ALS and FTD: Disrupted RNA and protein homeostasis
    • Ling, S. C., Polymenidou, M., Cleveland, D. W. Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron 79, 416-438 (2013).
    • (2013) Neuron , vol.79 , pp. 416-438
    • Ling, S.C.1    Polymenidou, M.2    Cleveland, D.W.3
  • 8
    • 77956392186 scopus 로고    scopus 로고
    • Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)
    • Cox, L. E. et al. Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS). PLoS ONE 5, e9872 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e9872
    • Cox, L.E.1
  • 9
    • 23044471011 scopus 로고    scopus 로고
    • Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
    • Skibinski, G. et al. Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nat. Genet. 37, 806-808 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 806-808
    • Skibinski, G.1
  • 10
    • 84901272549 scopus 로고    scopus 로고
    • Rare autosomal copy number variations in early-onset familial Alzheimer's disease
    • Hooli, B. V. et al. Rare autosomal copy number variations in early-onset familial Alzheimer's disease. Mol. Psychiatry 19, 676-681 (2014).
    • (2014) Mol. Psychiatry , vol.19 , pp. 676-681
    • Hooli, B.V.1
  • 12
    • 77954957013 scopus 로고    scopus 로고
    • Membrane budding and scission by the ESCRT machinery: It's all in the neck
    • Hurley, J. H., Hanson, P. I. Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat. Rev. Mol. Cell Biol. 11, 556-566 (2010).
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 556-566
    • Hurley, J.H.1    Hanson, P.I.2
  • 13
    • 77956902003 scopus 로고    scopus 로고
    • CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines
    • Belly, A. et al. CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines. J. Cell Sci. 123, 2943-2954 (2010).
    • (2010) J. Cell Sci. , vol.123 , pp. 2943-2954
    • Belly, A.1
  • 14
    • 84857568926 scopus 로고    scopus 로고
    • Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice
    • Ghazi-Noori, S. et al. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain 135, 819-832 (2012).
    • (2012) Brain , vol.135 , pp. 819-832
    • Ghazi-Noori, S.1
  • 15
    • 34548492271 scopus 로고    scopus 로고
    • ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
    • Lee, J. A., Beigneux, A., Ahmad, S. T., Young, S. G., Gao, F. B. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr. Biol. 17, 1561-1567 (2007).
    • (2007) Curr. Biol. , vol.17 , pp. 1561-1567
    • Lee, J.A.1    Beigneux, A.2    Ahmad, S.T.3    Young, S.G.4    Gao, F.B.5
  • 16
    • 67649996222 scopus 로고    scopus 로고
    • Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia
    • Lee, J. A., Gao, F. B. Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia. J. Neurosci. 29, 8506-8511 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 8506-8511
    • Lee, J.A.1    Gao, F.B.2
  • 17
    • 84871609151 scopus 로고    scopus 로고
    • MicroRNAs and neurodegeneration: Role and impact
    • Abe, M., Bonini, N. M. MicroRNAs and neurodegeneration: role and impact. Trends Cell Biol. 23, 30-36 (2013).
    • (2013) Trends Cell Biol. , vol.23 , pp. 30-36
    • Abe, M.1    Bonini, N.M.2
  • 18
    • 84862202857 scopus 로고    scopus 로고
    • Cause or effect: Misregulation of microRNA pathways in neurodegeneration
    • Gascon, E., Gao, F. B. Cause or effect: misregulation of microRNA pathways in neurodegeneration. Front. Neurosci. 6, 48 (2012).
    • (2012) Front. Neurosci. , vol.6 , pp. 48
    • Gascon, E.1    Gao, F.B.2
  • 19
    • 77957194193 scopus 로고    scopus 로고
    • Context-dependent functions of specific microRNAs in neuronal development
    • Gao, F. B. Context-dependent functions of specific microRNAs in neuronal development. Neural Dev. 5, 25 (2010).
    • (2010) Neural Dev. , vol.5 , pp. 25
    • Gao, F.B.1
  • 20
    • 80052563319 scopus 로고    scopus 로고
    • Neocortical excitation/inhibition balance in information processing and social dysfunction
    • Yizhar, O. et al. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 477, 171-178 (2011).
    • (2011) Nature , vol.477 , pp. 171-178
    • Yizhar, O.1
  • 21
    • 79955536349 scopus 로고    scopus 로고
    • Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
    • Pecą, J. et al. Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature 472, 437-442 (2011).
    • (2011) Nature , vol.472 , pp. 437-442
    • Pecą, J.1
  • 22
    • 84864981763 scopus 로고    scopus 로고
    • Advances in understanding the molecular basis of frontotemporal dementia
    • Rademakers, R., Neumann, M., Mackenzie, I. R. Advances in understanding the molecular basis of frontotemporal dementia. Nat. Rev. Neurol. 8, 423-434 (2012).
    • (2012) Nat. Rev. Neurol. , vol.8 , pp. 423-434
    • Rademakers, R.1    Neumann, M.2    MacKenzie, I.R.3
  • 24
    • 34249933982 scopus 로고    scopus 로고
    • Do thin spines learn to be mushroom spines that remember?
    • Bourne, J., Harris, K. M. Do thin spines learn to be mushroom spines that remember? Curr. Opin. Neurobiol. 17, 381-386 (2007).
    • (2007) Curr. Opin. Neurobiol. , vol.17 , pp. 381-386
    • Bourne, J.1    Harris, K.M.2
  • 27
    • 0028054910 scopus 로고
    • Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy
    • Namba, T., Morimoto, K., Sato, K., Yamada, N., Kuroda, S. Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638, 36-44 (1994).
    • (1994) Brain Res. , vol.638 , pp. 36-44
    • Namba, T.1    Morimoto, K.2    Sato, K.3    Yamada, N.4    Kuroda, S.5
  • 28
    • 65249185511 scopus 로고    scopus 로고
    • Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach
    • Lu, W. et al. Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach. Neuron 62, 254-268 (2009).
    • (2009) Neuron , vol.62 , pp. 254-268
    • Lu, W.1
  • 29
    • 84857260327 scopus 로고    scopus 로고
    • GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: Evidence from gene-targeted mice
    • Rozov, A., Sprengel, R., Seeburg, P. H. GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: evidence from gene-targeted mice. Front. Mol. Neurosci. 5, 22 (2012).
    • (2012) Front. Mol. Neurosci. , vol.5 , pp. 22
    • Rozov, A.1    Sprengel, R.2    Seeburg, P.H.3
  • 30
    • 33745202578 scopus 로고    scopus 로고
    • Regulation of Ca2+-permeable AMPA receptors: Synaptic plasticity and beyond
    • Cull-Candy, S., Kelly, L., Farrant, M. Regulation of Ca2+-permeable AMPA receptors: synaptic plasticity and beyond. Curr. Opin. Neurobiol. 16, 288-297 (2006).
    • (2006) Curr. Opin. Neurobiol. , vol.16 , pp. 288-297
    • Cull-Candy, S.1    Kelly, L.2    Farrant, M.3
  • 31
    • 33847125205 scopus 로고    scopus 로고
    • Ca2+-permeable AMPA receptors in synaptic plasticity and neuronal death
    • Liu, S. J., Zukin, R. S. Ca2+-permeable AMPA receptors in synaptic plasticity and neuronal death. Trends Neurosci. 30, 126-134 (2007).
    • (2007) Trends Neurosci. , vol.30 , pp. 126-134
    • Liu, S.J.1    Zukin, R.S.2
  • 32
    • 24744431841 scopus 로고    scopus 로고
    • Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death
    • Noh, K. M. et al. Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death. Proc. Natl. Acad. Sci. USA 102, 12230-12235 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 12230-12235
    • Noh, K.M.1
  • 33
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. The functions of animal microRNAs. Nature 431, 350-355 (2004).
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 34
    • 79960903902 scopus 로고    scopus 로고
    • MicroRNAs in neurons: Manifold regulatory roles at the synapse
    • Siegel, G., Saba, R., Schratt, G. microRNAs in neurons: manifold regulatory roles at the synapse. Curr. Opin. Genet. Dev. 21, 491-497 (2011).
    • (2011) Curr. Opin. Genet. Dev. , vol.21 , pp. 491-497
    • Siegel, G.1    Saba, R.2    Schratt, G.3
  • 35
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
    • Deo, M., Yu, J. Y., Chung, K. H., Tippens, M., Turner, D. L. Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn. 235, 2538-2548 (2006).
    • (2006) Dev. Dyn. , vol.235 , pp. 2538-2548
    • Deo, M.1    Yu, J.Y.2    Chung, K.H.3    Tippens, M.4    Turner, D.L.5
  • 36
    • 84870401656 scopus 로고    scopus 로고
    • Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects
    • Almeida, S. et al. Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects. Cell Reports 2, 789-798 (2012).
    • (2012) Cell Reports , vol.2 , pp. 789-798
    • Almeida, S.1
  • 37
    • 84883465132 scopus 로고    scopus 로고
    • Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
    • Almeida, S. et al. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathol. 126, 385-399 (2013).
    • (2013) Acta Neuropathol. , vol.126 , pp. 385-399
    • Almeida, S.1
  • 38
    • 84865008239 scopus 로고    scopus 로고
    • TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways
    • Chen-Plotkin, A. S. et al. TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways. J. Neurosci. 32, 11213-11227 (2012).
    • (2012) J. Neurosci. , vol.32 , pp. 11213-11227
    • Chen-Plotkin, A.S.1
  • 39
    • 84877117884 scopus 로고    scopus 로고
    • A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with Lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls
    • Hébert, S. S., Wang, W. X., Zhu, Q., Nelson, P. T. A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with Lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls. J. Alzheimers Dis. 35, 335-348 (2013).
    • (2013) J. Alzheimers Dis. , vol.35 , pp. 335-348
    • Hébert, S.S.1    Wang, W.X.2    Zhu, Q.3    Nelson, P.T.4
  • 40
    • 43049143907 scopus 로고    scopus 로고
    • Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration
    • Chen-Plotkin, A. S. et al. Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration. Hum. Mol. Genet. 17, 1349-1362 (2008).
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1349-1362
    • Chen-Plotkin, A.S.1
  • 41
    • 51449089054 scopus 로고    scopus 로고
    • Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia
    • van Swieten, J. C., Heutink, P. Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia. Lancet Neurol. 7, 965-974 (2008).
    • (2008) Lancet Neurol. , vol.7 , pp. 965-974
    • Van Swieten, J.C.1    Heutink, P.2
  • 42
    • 80555150639 scopus 로고    scopus 로고
    • Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex
    • Wang, F. et al. Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex. Science 334, 693-697 (2011).
    • (2011) Science , vol.334 , pp. 693-697
    • Wang, F.1
  • 43
    • 78751579187 scopus 로고    scopus 로고
    • Behavioural-variant frontotemporal dementia: Diagnosis, clinical staging, and management
    • Piguet, O., Hornberger, M., Mioshi, E., Hodges, J. R. Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management. Lancet Neurol. 10, 162-172 (2011).
    • (2011) Lancet Neurol. , vol.10 , pp. 162-172
    • Piguet, O.1    Hornberger, M.2    Mioshi, E.3    Hodges, J.R.4
  • 44
    • 84877099960 scopus 로고    scopus 로고
    • Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice
    • Filiano, A. J. et al. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. J. Neurosci. 33, 5352-5361 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 5352-5361
    • Filiano, A.J.1
  • 45
    • 84863456653 scopus 로고    scopus 로고
    • Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia
    • Kim, E. J. et al. Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia. Cereb. Cortex 22, 251-259 (2012).
    • (2012) Cereb. Cortex , vol.22 , pp. 251-259
    • Kim, E.J.1
  • 46
    • 84862777622 scopus 로고    scopus 로고
    • GluA3-deficiency in mice is associated with increased social and aggressive behavior and elevated dopamine in striatum
    • Adamczyk, A. et al. GluA3-deficiency in mice is associated with increased social and aggressive behavior and elevated dopamine in striatum. Behav. Brain Res. 229, 265-272 (2012).
    • (2012) Behav. Brain Res. , vol.229 , pp. 265-272
    • Adamczyk, A.1
  • 47
    • 84879813477 scopus 로고    scopus 로고
    • The synaptic maintenance problem: Membrane recycling, Ca2+ homeostasis and late onset degeneration
    • Bezprozvanny, I., Hiesinger, P. R. The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degeneration. Mol. Neurodegener. 8, 23 (2013).
    • (2013) Mol. Neurodegener. , vol.8 , pp. 23
    • Bezprozvanny, I.1    Hiesinger, P.R.2
  • 48
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • Gibbings, D. J., Ciaudo, C., Erhardt, M., Voinnet, O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat. Cell Biol. 11, 1143-1149 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 49
    • 69949185018 scopus 로고    scopus 로고
    • Silencing by small RNAs is linked to endosomal trafficking
    • Lee, Y. S. et al. Silencing by small RNAs is linked to endosomal trafficking. Nat. Cell Biol. 11, 1150-1156 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1150-1156
    • Lee, Y.S.1
  • 50
    • 84878276240 scopus 로고    scopus 로고
    • Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors
    • Dutta, R. et al. Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors. Ann. Neurol. 73, 637-645 (2013).
    • (2013) Ann. Neurol. , vol.73 , pp. 637-645
    • Dutta, R.1
  • 51
    • 84871843346 scopus 로고    scopus 로고
    • Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor
    • Prudencio, M. et al. Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor. Proc. Natl. Acad. Sci. USA 109, 21510-21515 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 21510-21515
    • Prudencio, M.1
  • 52
    • 35148879034 scopus 로고    scopus 로고
    • Mouse social recognition and preference
    • Winslow, J. T. Mouse social recognition and preference. Curr. Protoc. Neurosci. 22, 8-16 (2003).
    • (2003) Curr. Protoc. Neurosci. , vol.22 , pp. 8-16
    • Winslow, J.T.1
  • 54
    • 84888329298 scopus 로고    scopus 로고
    • Object recognition test in mice
    • Leger, M. et al. Object recognition test in mice. Nat. Protoc. 8, 2531-2537 (2013).
    • (2013) Nat. Protoc. , vol.8 , pp. 2531-2537
    • Leger, M.1
  • 55
    • 44349154735 scopus 로고    scopus 로고
    • Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images
    • Rodriguez, A., Ehlenberger, D. B., Dickstein, D. L., Hof, P. R., Wearne, S. L. Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PLoS One 3, e1997 (2008).
    • (2008) PLoS One , vol.3 , pp. e1997
    • Rodriguez, A.1    Ehlenberger, D.B.2    Dickstein, D.L.3    Hof, P.R.4    Wearne, S.L.5
  • 57
    • 33747754760 scopus 로고    scopus 로고
    • Lessons from Nature: MicroRNA-based shRNA libraries
    • Chang, K., Elledge, S. J., Hannon, G. J. Lessons from Nature: microRNA-based shRNA libraries. Nat. Methods 3, 707-714 (2006).
    • (2006) Nat. Methods , vol.3 , pp. 707-714
    • Chang, K.1    Elledge, S.J.2    Hannon, G.J.3
  • 58
    • 84868158039 scopus 로고    scopus 로고
    • Introducing genes into mammalian cells: Viral vectors
    • (eds. Green, M. R. and Sambrook, J (Cold Spring Harbor Laboratory Press, New York
    • Gao, G. P., Sena-Esteves, M. Introducing genes into mammalian cells: viral vectors. in Molecular Cloning, Vol 2: A Laboratory Manual (eds. Green, M. R. and Sambrook, J. ) 1209-1313 (Cold Spring Harbor Laboratory Press, New York, 2012).
    • (2012) Molecular Cloning,: A Laboratory Manual , vol.2 , pp. 1209-1313
    • Gao, G.P.1    Sena-Esteves, M.2
  • 59
    • 64749107970 scopus 로고    scopus 로고
    • Production concentration and titration of pseudotyped HIV-1-based lentiviral vectors
    • Kutner, R. H., Zhang, X. Y., Reiser, J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat. Protoc. 4, 495-505 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 495-505
    • Kutner, R.H.1    Zhang, X.Y.2    Reiser, J.3
  • 61
    • 77956802041 scopus 로고    scopus 로고
    • Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons
    • Gascon, E. et al. Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons. J. Neurosci. 30, 12414-12423 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 12414-12423
    • Gascon, E.1
  • 62
    • 34247372728 scopus 로고    scopus 로고
    • PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: A crucial role in regulating p75 expression and cell survival
    • Gascon, E., Vutskits, L., Jenny, B., Durbec, P., Kiss, J. Z. PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival. Development 134, 1181-1190 (2007).
    • (2007) Development , vol.134 , pp. 1181-1190
    • Gascon, E.1    Vutskits, L.2    Jenny, B.3    Durbec, P.4    Kiss, J.Z.5


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