IL-15 superagonist expands mCD8+T, NK and NKT cells after burn injury but fails to improve outcome during burn wound infection

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Patil, Naeem K ^a   Luan, Liming ^a   Bohannon, Julia K ^a   Guo, Yin ^a   Hernandez, Antonio ^a   Fensterheim, Benjamin ^a   Sherwood, Edward R ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; INTERLEUKIN 15; CYTOKINE; HYBRID PROTEIN; IL15RA PROTEIN, MOUSE; INTERLEUKIN 15 RECEPTOR;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL CLEARANCE; BODY SURFACE; BURN; BURN INFECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; LEUKOCYTE; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MOUSE; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; OUTCOME ASSESSMENT; PSEUDOMONAS INFECTION; T LYMPHOCYTE ACTIVATION; AGONISTS; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; BURNS; COMPLICATION; DISEASE MODEL; HUMAN; IMMUNOLOGY; LIVER; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; MALE; PATHOLOGY; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SPLEEN; WOUND INFECTION;

ADAPTIVE IMMUNITY; ANIMALS; BURNS; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-15; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE SUBSETS; MALE; MICE; MICE, INBRED BALB C; NATURAL KILLER T-CELLS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RECEPTORS, INTERLEUKIN-15; RECOMBINANT FUSION PROTEINS; SPLEEN; WOUND INFECTION;

EID: 84959238664     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148452     Document Type: Article

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