Converting IL-15 to a superagonist by binding to soluble IL-15Rα

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 24, 2006, Pages 9166-9171

  Rubinstein, Mark P ^a   Kovar, Marek ^c   Purton, Jared F ^a   Cho, Jae Ho ^a,b   Boyman, Onur ^a   Surh, Charles D ^a   Sprent, Jonathan ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

CD122; Cytokines; Natural killer cells; Soluble receptors; T cells

Indexed keywords

CD8 ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; HUMANS; INTERLEUKIN-15; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS;

EID: 33745135757     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0600240103     Document Type: Article

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