Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models

Molecular Neurodegeneration

Volumn 11, Issue 1, 2016, Pages

  Cornaglia, Matteo ^a   Krishnamani, Gopalan ^a   Mouchiroud, Laurent ^a   Sorrentino, Vincenzo ^a   Lehnert, Thomas ^a   Auwerx, Johan ^a   Gijs, Martin A M ^a  

^a EPFL   (Switzerland)

Author keywords

Amyotrophic lateral sclerosis (ALS); Caenorhabditis elegans; Doxycycline treatment; High resolution imaging; Huntington disease (HD); Longitudinal time resolved analysis; Microfluidics; Neurodegenerative disease; Protein aggregation; Temperature control; Worm immobilization

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; DOXYCYCLINE; YELLOW FLUORESCENT PROTEIN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOMATION; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEVELOPMENT; EQUIPMENT DESIGN; GROWTH RATE; HUNTINGTON CHOREA; IMAGING; IMMOBILIZATION; IN VIVO STUDY; MICROFLUIDIC ANALYSIS; MICROFLUIDICS; MONITORING; NONHUMAN; ON CHIP HIGH RESOLUTION IMAGING; PROTEIN AGGREGATION; ANIMAL; DISEASE MODEL; METABOLISM; TEMPERATURE;

ANIMALS; CAENORHABDITIS ELEGANS; DISEASE MODELS, ANIMAL; DOXYCYCLINE; SUPEROXIDE DISMUTASE; TEMPERATURE;

EID: 84958770364     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-016-0083-6     Document Type: Article

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