Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model

Journal of Neuroscience

Volumn 26, Issue 29, 2006, Pages 7597-7606

  Brignull, Heather R ^a   Moore, Finola E ^a   Tang, Stephanie J ^a   Morimoto, Richard I ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Aggregates; C. elegans; FRAP; FRET; Neurotoxicity; Polyglutamine

Indexed keywords

GLUTAMINE DERIVATIVE; POLYGLUTAMINE; CAENORHABDITIS ELEGANS PROTEIN; PEPTIDE;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; MOTONEURON; NERVE CELL; NERVE CELL MEMBRANE; NEUROTOXICITY; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; ANIMAL; ANIMAL MODEL; BIOPHYSICS; CHEMISTRY; METABOLISM; NERVOUS SYSTEM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN CONFORMATION; TISSUE DISTRIBUTION;

ANIMALS; BIOPHYSICS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; MODELS, ANIMAL; NERVOUS SYSTEM; NEURONS; PEPTIDES; PROTEIN CONFORMATION; PROTEIN FOLDING; TISSUE DISTRIBUTION;

EID: 33747053662     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0990-06.2006     Document Type: Article

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