Anticancer activity of glucomoringin isothiocyanate in human malignant astrocytoma cells

Fitoterapia

Volumn 110, Issue , 2016, Pages 1-7

  Rajan, Thangavelu Soundara ^a   De Nicola, Gina Rosalinda ^b   Iori, Renato ^b   Rollin, Patrick ^c   Bramanti, Placido ^a   Mazzon, Emanuela ^a  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^c UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

Anti tumor effects; Apoptosis; Glioblastoma multiforme; Glucomoringin; Isothiocyanates; Moringa oleifera; Oxidative stress

Indexed keywords

ANTINEOPLASTIC AGENT; GENOMIC DNA; GLUCOMORINGIN ISOTHIOCYANATE; MORINGIN; PROTEIN BCL 2; RNA 5S; THIOGLUCOSIDASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 4-((ALPHA-L-RHAMNOSYLOXY)BENZYL)ISOTHIOCYANATE; ISOTHIOCYANIC ACID DERIVATIVE; RHAMNOSE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTOMA; CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; OXIDATIVE STRESS; PH; PRIORITY JOURNAL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; MORINGA; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ASTROCYTOMA; CELL LINE, TUMOR; HUMANS; ISOTHIOCYANATES; MOLECULAR STRUCTURE; MORINGA; OXIDATIVE STRESS; RHAMNOSE;

EID: 84958767941     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2016.02.007     Document Type: Article

References (46)

1. J.W. Fahey, A.T. Zalcmann, and P. Talalay The chemical diversity and distribution of glucosinolates and isothiocyanates among plants Phytochemistry 56 2001 5 51
2. A.F. Abdull Razis, M. Bagatta, G.R. De Nicola, R. Iori, and C. Ioannides Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin Lung Cancer 71 2011 298 305
3. N. Agerbirk, and C.E. Olsen Glucosinolate structures in evolution Phytochemistry 77 2012 16 45
4. A.T. Dinkova-Kostova, and R.V. Kostov Glucosinolates and isothiocyanates in health and disease Trends Mol. Med. 18 2012 337 347
5. Y.S. Keum, W.S. Jeong, and A.N. Kong Chemopreventive functions of isothiocyanates Drug News Perspect. 18 2005 445 451
6. B. Padayachee, and H. Baijnath An overview of the medicinal importance of Moringaceae J. Med. Plant Res. 6 2012 5831 5839
7. S.K. Biswas, A. Chowdhury, J. Das, A. Roy, and S.M. Zahid Hosen Pharmacological potentials of Moringa oleifera Lam.: a review Int. J. Pharm. Sci. Res. 47 2012 305 310
8. A.R. Verma, M. Vijayakumar, C.S. Mathela, and C.V. Rao In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves Food Chem. Toxicol. 47 2009 2196 2201
9. D. Brunelli, M. Tavecchio, C. Falcioni, R. Frapolli, E. Erba, R. Iori, and et al. The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo Biochem. Pharmacol. 79 2010 1141 1148
10. Q.T. Ostrom, H. Gittleman, P. Farah, A. Ondracek, Y. Chen, Y. Wolinsky, and et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006-2010 Neuro-Oncology 15 15 2013 1 56 10.1093/neuonc/not151
11. R. Stupp, W.P. Mason, M.J. van den Bent, M. Weller, B. Fisher, M.J. Taphoorn, and et al. European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group, Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N. Engl. J. Med. 352 2005 987 996
12. L. Portt, G. Norman, C. Clapp, M. Greenwood, and M.T. Greenwood Anti-apoptosis and cell survival: a review Biochim. Biophys. Acta 1813 2011 238 259
13. Y. Fuchs, and H. Steller Programmed cell death in animal development and disease Cell 147 2011 742 758
14. M.M. Pore, T.J. Hiltermann, and F.A. Kruyt Targeting apoptosis pathways in lung cancer Cancer Lett. 332 2013 359 368
15. M. Signore, L. Ricci-Vitiani, and R. De Maria Targeting apoptosis pathways in cancer stem cells Cancer Lett. 332 2013 374 382
16. K. Block, C. Gyllenhaal, L. Lowe, A. Amedei, A.R. Amin, A. Amin, and et al. Designing a broad-spectrum integrative approach for cancer prevention and treatment Semin. Cancer Biol. 35 2015 276 304 10.1016/j.semcancer.2015.09.007
17. EEC regulation 1864/90, enclosure VIII Off. J. Eur. Communities L170 1990 27 34
18. A. Pessina, R.M. Thomas, S. Palmieri, and P.L. Luisi An improved method for the purification of myrosinase and its physicochemical characterization Arch. Biochem. Biophys. 280 1990 383 389
19. M. Galuppo, G.R. Nicola, R. Iori, P. Dell'utri, P. Bramanti, and E. Mazzon Antibacterial activity of glucomoringin bioactivated with myrosinase against two important pathogens affecting the health of long-term patients in hospitals Molecules 18 2013 14340 14348
20. F. Fuentes, X. Paredes-Gonzalez, and A.T. Kong Dietary glucosinolates sulforaphane, phenethyl isothiocyanate, indole-3-carbinol/3,3′-diindolylmethane: anti-oxidative stress/inflammation, Nrf2, epigenetics/epigenomics and in vivo cancer chemopreventive efficacy Curr. Pharmacol. Rep. 1 2015 179 196
21. N.S. Alrawaiq, and A. Abdullah An evaluation of sulforaphane as a potential agent for disease prevention Res. J. Pharm. Biol. Chem. Sci. 5 2014 1335 1349
22. V. Calabrese, C. Cornelius, A.T. Dinkova-Kostova, I. Iavicoli, R. Di Paola, A. Koverech, and et al. Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity Biochim. Biophys. Acta 1822 2012 753 783
23. N.G. Chen, K.T. Chen, C.C. Lu, Y.H. Lan, C.H. Lai, Y.T. Chung, and et al. Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway Oncol. Rep. 24 2010 449 455
24. Y.C. Chou, M.Y. Chang, M.J. Wang, T. Harnod, C.H. Hung, H.T. Lee, and et al. PEITC induces apoptosis of human brain glioblastoma GBM8401 cells through the extrinsic- and intrinsic -signaling pathways Neurochem. Int. 81 2015 32 40
25. D.H. Lee, D.W. Kim, H.C. Lee, J.H. Lee, and T.H. Lee Phenethyl isothiocyanate sensitizes glioma cells to TRAIL-induced apoptosis Biochem. Biophys. Res. Commun. 446 2014 815 821
26. S.K. Srivastava, and S.V. Singh Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells Carcinogenesis 25 2004 1701 1709
27. L. Tang, and Y. Zhang Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells Mol. Cancer Ther. 4 2005 1250 1259
28. C. Fimognari, M. Nüsse, R. Cesari, R. Iori, G. Cantelli-Forti, and P. Hrelia Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane Carcinogenesis 23 2002 581 586
29. M.J. Chen, W.Y. Tang, C.W. Hsu, Y.T. Tsai, J.F. Wu, and C.W. Lin Apoptosis induction in primary human colorectal cancer cell lines and retarded tumor growth in SCID mice by sulforaphane Evid. Based Complement. Alternat. Med. 2012 10.1155/2012/415231 (Epub 2011 Jul 17)
30. H.S. Shang, Y.L. Shih, T.J. Lu, C.H. Lee, S.C. Hsueh, Y.C. Chou, and et al. Benzyl isothiocyanate (BITC) induces apoptosis of GBM 8401 human brain glioblastoma multiform cells via activation of caspase-8/Bid and the reactive oxygen species-dependent mitochondrial pathway Environ. Toxicol. 2015 10.1002/tox.22177
31. Y.R. Chen, W. Wang, A.N. Kong, and T.H. Tan Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates J. Biol. Chem. 273 1998 1769 1775
32. L. Mi, X. Wang, S. Govind, B.L. Hood, T.D. Veenstra, T.P. Conrads, and et al. The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells Cancer Res. 67 2007 6409 6416
33. Y. Nakamura, H. Ohigashi, S. Masuda, A. Murakami, Y. Morimitsu, Y. Kawamoto, and et al. Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates Cancer Res. 60 2000 219 225
34. D. Xiao, V. Vogel, and S.V. Singh Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak Mol. Cancer Ther. 5 2006 2931 2945
35. R. Yu, S. Mandlekar, K.J. Harvey, D.S. Ucker, and A.N. Kong Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity Cancer Res. 58 1998 402 408
36. R.K. Lin, N. Zhou, Y.L. Lyu, Y.C. Tsai, C.H. Lu, J. Kerrigan, and et al. Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα J. Biol. Chem. 286 2011 33591 33600
37. S. Mas, A. Crescenti, P. Gassó, R. Deulofeu, R. Molina, A. Ballesta, and et al. Induction of apoptosis in HT-29 cells by extracts from isothiocyanates-rich varieties of Brassica oleracea Nutr. Cancer 58 2007 107 114
38. R.U. Jänicke, M.L. Sprengart, M.R. Wati, and A.G. Porter Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis J. Biol. Chem. 273 1998 9357 9360
39. B.B. Wolf, M. Schuler, F. Echeverri, and D.R. Green Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation J. Biol. Chem. 274 1999 30651 30656
40. R. Leone, P. Giussani, S. De Palma, C. Fania, D. Capitanio, M. Vasso, and et al. Proteomic analysis of human glioblastoma cell lines differently resistant to a nitric oxide releasing agent Mol. BioSyst. 11 2015 1612 1621
41. J. Xu, Z. Li, J. Wang, H. Chen, and J.Y. Fang Combined PTEN mutation and protein expression associate with overall and disease-free survival of glioblastoma patients Transl. Oncol. 7 2014 196 205
42. K. Nishimura, T. Kumazawa, T. Kuroda, N. Katagiri, M. Tsuchiya, N. Goto, and et al. Perturbation of ribosome biogenesis drives cells into senescence through 5S RNP-mediated p53 activation Cell Rep. 10 2015 1310 1323
43. K.E. Sloan, M.T. Bohnsack, and N.J. Watkins The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress Cell Rep. 5 2013 237 247
44. T. Kumazawa, K. Nishimura, N. Katagiri, S. Hashimoto, Y. Hayashi, and K. Kimura Gradual reduction in rRNA transcription triggers p53 acetylation and apoptosis via MYBBP1A Sci. Rep. 2015 10.1038/srep10854
45. S. Bursac, M.C. Brdovcak, G. Donati, and S. Volarevic Activation of the tumor suppressor p53 upon impairment of ribosome biogenesis Biochim. Biophys. Acta 1842 2014 817 830
46. V. Dufour, M. Stahl, E. Rosenfeld, A. Stintzi, and C. Baysse Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni Appl. Environ. Microbiol. 79 2013 6958 6968