Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway

Oncology Reports

Volumn 24, Issue 2, 2010, Pages 449-455

  Chen, Nian Gu ^a   Chen, Kuan Tin ^b   Lu, Chi Cheng ^a   Lan, Yu Hsuan ^c   Lai, Cheng Hung ^a   Chung, Yang Tsung ^a   Yang, Jai Sing ^b   Lin, Yung Chang ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Allyl isothiocyanate; Apoptosis; G2 M arrest; Human brain malignant glioma GBM 8401 cells; Mitochondria

Indexed keywords

ALLYL ISOTHIOCYANATE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CYCLIN B; CYTOCHROME C; PROCASPASE 9; CYTOSTATIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVITY; GLIOMA; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BIOLOGICAL MODEL; BRAIN TUMOR; CELL DIVISION; DRUG EFFECTS; DRUG SCREENING; HL 60 CELL LINE; HT 29 CELL LINE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE;

APOPTOSIS; BRAIN NEOPLASMS; CELL DIVISION; CELL PROLIFERATION; CYTOSTATIC AGENTS; DRUG EVALUATION, PRECLINICAL; G2 PHASE; GLIOMA; HL-60 CELLS; HT29 CELLS; HUMANS; ISOTHIOCYANATES; MITOCHONDRIA; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 77954362203     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000878     Document Type: Article

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