PEITC induces apoptosis of Human Brain Glioblastoma GBM8401 Cells through the extrinsic- and intrinsic -signaling pathways

Neurochemistry International

Volumn 81, Issue , 2015, Pages 32-40

  Chou, Yu Cheng ^a,b,c,d   Chang, Meng Ya ^b   Wang, Mei Jen ^b   Harnod, Tomor ^b   Hung, Chih Huang ^b   Lee, Hsu Tung ^a,c   Shen, Chiung Chyi ^a   Chung, Jing Gung ^e,f  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

^f ASIA UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Caspases; Glioblastoma; Mitochondria; PEITC

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; PHENETHYL ISOTHIOCYANATE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; CALCIUM; ISOTHIOCYANIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BRAIN TUMOR; DRUG EFFECTS; GLIOBLASTOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; BRAIN NEOPLASMS; CALCIUM; CELL LINE, TUMOR; GLIOBLASTOMA; HUMANS; ISOTHIOCYANATES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84922359898     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2015.01.001     Document Type: Article

References (41)

1. Antosiewicz J., Ziolkowski W., Kar S., Powolny A.A., and Singh S.V. Role of reactive oxygen intermediates in cellular responses to dietary cancer chemopreventive agents Planta Med 74 2008 1570 1579
2. Budihardjo I., Oliver H., Lutter M., Luo X., and Wang X. Biochemical pathways of caspase activation during apoptosis Annu. Rev. Cell Dev. Biol 15 1999 269 290
3. Chaichana K.L. Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma Neuro-Oncol 16 2014 113 122
4. Chen Y.R., Han J., Kori R., Kong A.N., and Tan T.H. Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase J. Biol. Chem 277 2002 39334 39342
5. Cui W., Ma J., Wang X., Yang W., Zhang J., and Ji Q. Free fatty acid induces endoplasmic reticulum stress and apoptosis of beta-cells by Ca2+/calpain-2 pathways PLoS ONE 8 2013 e59921
6. Ghobrial I.M., Witzig T.E., and Adjei A.A. Targeting apoptosis pathways in cancer therapy CA Cancer J. Clin 55 2005 178 194
7. Gotoh T., Terada K., Oyadomari S., and Mori M. hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria Cell Death Differ 11 2004 390 402
8. Gupta B., Chiang L., Chae K., and Lee D.H. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1alpha and VEGF expression in human glioma cells Food Chem 141 2013 1841 1846
9. Hamamura K., and Yokota H. Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling FEBS Lett 581 2007 1769 1774
10. Hecht S.S. Chemoprevention by isothiocyanates J. Cell. Biochem. Suppl 22 1995 195 209
11. Ho C.C. Ellagic acid induces apoptosis in tsgh8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways Environ. Toxicol 2013 10.1002/tox.21857
12. Hu R., Kim B.R., Chen C., Hebbar V., and Kong A.N. The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells Carcinogenesis 24 2003 1361 1367
13. Jakubikova J., Bao Y., and Sedlak J. Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines Anticancer Res 25 2005 3375 3386
14. Jakubowicz-Gil J., Langner E., Badziul D., Wertel I., and Rzeski W. Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment Tumour Biol 34 2013 2367 2378
15. Jin Z., and El-Deiry W.S. Overview of cell death signaling pathways Cancer Biol. Ther 4 2005 139 163
16. Kang L., and Wang Z.Y. Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-alpha36 J. Cell. Mol. Med 14 2010 1485 1493
17. Kim D.S., Jeong S.K., Kim H.R., Kim D.S., Chae S.W., and Chae H.J. Effects of triglyceride on ER stress and insulin resistance Biochem. Biophys. Res. Commun 363 2007 140 145
18. Lee D.H., Kim D.W., Lee H.C., Lee J.H., and Lee T.H. Phenethyl isothiocyanate sensitizes glioma cells to TRAIL-induced apoptosis Biochem. Biophys. Res. Commun 446 2014 815 821
19. Lin C.J., Lee C.C., Shih Y.L., Lin C.H., Wang S.H., and Chen T.H. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells PLoS ONE 7 2012 e38706
20. Lovat P.E., Oliverio S., Corazzari M., Rodolfo C., Ranalli M., and Goranov B. Bak: a downstream mediator of fenretinide-induced apoptosis of SH-SY5Y neuroblastoma cells Cancer Res 63 2003 7310 7313
21. Lu H.F., Lai T.Y., Hsia T.C., Tang Y.J., Yang J.S., and Chiang J.H. Danthron induces DNA damage and inhibits DNA repair gene expressions in GBM 8401 human brain glioblastoma multiforms cells Neurochem. Res 35 2010 1105 1110
22. Lu H.F. Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma multiforms GBM 8401 cells Neurochem. Res 35 2010 390 398
23. McIlwain D.R., Berger T., and Mak T.W. Caspase functions in cell death and disease Cold Spring Harb. Perspect. Biol 5 2013 a008656
24. Moon Y.J., Brazeau D.A., and Morris M.E. Dietary phenethyl isothiocyanate alters gene expression in human breast cancer cells Evid. Based Complement. Alternat. Med 2011 2011 462525
25. Nishikawa A., Furukawa F., Lee I.S., Tanaka T., and Hirose M. Potent chemopreventive agents against pancreatic cancer Curr. Cancer Drug Targets 4 2004 373 384
26. Oyadomari S., Koizumi A., Takeda K., Gotoh T., Akira S., and Araki E. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes J. Clin. Invest 109 2002 525 532
27. Saelens X., Festjens N., Vande Walle L., van Gurp M., van Loo G., and Vandenabeele P. Toxic proteins released from mitochondria in cell death Oncogene 23 2004 2861 2874
28. Stupp R. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N. Engl. J. Med 352 2005 987 996
29. Tajiri S., Oyadomari S., Yano S., Morioka M., Gotoh T., and Hamada J.I. Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP Cell Death Differ 11 2004 403 415
30. Telang U., Brazeau D.A., and Morris M.E. Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells Exp. Biol. Med. (Maywood) 234 2009 287 295
31. Tseng E., Scott-Ramsay E.A., and Morris M.E. Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines Exp. Biol. Med. (Maywood) 229 2004 835 842
32. von Weymarn L.B., Chun J.A., and Hollenberg P.F. Effects of benzyl and phenethyl isothiocyanate on P450s 2A6 and 2A13: potential for chemoprevention in smokers Carcinogenesis 27 2006 782 790
33. Wajant H. The Fas signaling pathway: more than a paradigm Science 296 2002 1635 1636
34. Wang D.Y., Yeh C.C., Lee J.H., Hung C.F., and Chung J.G. Berberine inhibited arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells Neurochem. Res 27 2002 883 889
35. Wolf B.B., and Green D.R. Suicidal tendencies: apoptotic cell death by caspase family proteinases J. Biol. Chem 274 1999 20049 20052
36. Wu X.J., and Hua X. Targeting ROS: selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound Cancer Biol. Ther 6 2007 646 647
37. Xu C., Shen G., Chen C., Gelinas C., and Kong A.N. Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells Oncogene 24 2005 4486 4495
38. Xu K., and Thornalley P.J. Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro Biochem. Pharmacol 60 2000 221 231
39. Yang L.J., Zhou C.F., and Lin Z.X. Temozolomide and radiotherapy for newly diagnosed glioblastoma multiforme: a systematic review Cancer Invest 32 2014 31 36
40. Yu R., Mandlekar S., Harvey K.J., Ucker D.S., and Kong A.N. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity Cancer Res 58 1998 402 408
41. Zhai Y., Ding D., Wei L., Chen E., and Feng G. Interference of Mucin 1 inhibits the growth of liver cancer cells by inducing mitochondria-mediated and death receptor-mediated cell apoptosis Tumour Biol 2014 10.1007/s13277-014-2120-9