Loss of peripheral protection in pancreatic islets by proteolysis-driven impairment of VTCN1 (B7-H4) presentation is associated with the development of autoimmune diabetes

Journal of Immunology

Volumn 196, Issue 4, 2016, Pages 1495-1506

  Radichev, Ilian A ^a   Maneva Radicheva, Lilia V ^a   Amatya, Christina ^a   Salehi, Maryam ^a   Parker, Camille ^a   Ellefson, Jacob ^a   Burn, Paul ^a   Savinov, Alexei Y ^a,b  

^a SANFORD RESEARCH   (United States)

^b UNIVERSITY OF SOUTH DAKOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; METALLOPROTEINASE; NARDILYSIN; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1; VTCN1 PROTEIN, HUMAN; VTCN1 PROTEIN, MOUSE;

ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIGEN PRESENTATION; BIOSYNTHESIS; GENETICS; HUMAN; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PROTEIN DEGRADATION; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; CYTOKINES; DIABETES MELLITUS, TYPE 1; GLUCAGON-SECRETING CELLS; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; LYMPHOCYTE ACTIVATION; METALLOENDOPEPTIDASES; MICE, INBRED NOD; PROTEOLYSIS; T-LYMPHOCYTES; V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1;

EID: 84958567804     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1403251     Document Type: Article

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