The inhibitory role of B7-H4 in antitumor immunity: Association with cancer progression and survival

Clinical and Developmental Immunology

Volumn 2011, Issue , 2011, Pages

  He, Changjun ^a   Qiao, Haiquan ^a   Jiang, Hongchi ^a   Sun, Xueying ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1; TUMOR ANTIGEN; TUMOR MARKER; VTCN1 PROTEIN, HUMAN;

ADAPTIVE IMMUNITY; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; BREAST CANCER; BRENNER TUMOR; CANCER GROWTH; CANCER PATIENT; CANCER SURVIVAL; COLORECTAL CANCER; CYTOKINE PRODUCTION; ENDOMETRIOID CARCINOMA; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; HUMAN; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; KIDNEY CARCINOMA; LUNG NON SMALL CELL CANCER; MELANOMA; NONHUMAN; OVARY CANCER; PANCREAS ADENOCARCINOMA; PAPILLARY CARCINOMA; PRIORITY JOURNAL; PROSTATE CANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; STOMACH CANCER; TH1 CELL; TUMOR IMMUNITY; CELL TRANSFORMATION; DISEASE COURSE; GENE EXPRESSION REGULATION; GENETICS; IMMUNITY; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; MORTALITY; NEOPLASM; PROGNOSIS; SURVIVAL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR ESCAPE; TUMOR MICROENVIRONMENT;

ANTIGENS, NEOPLASM; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNITY; IMMUNOSUPPRESSION; LYMPHOCYTES, TUMOR-INFILTRATING; NEOPLASMS; PROGNOSIS; SURVIVAL ANALYSIS; TUMOR ESCAPE; TUMOR MARKERS, BIOLOGICAL; TUMOR MICROENVIRONMENT; V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1;

EID: 84855166172     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2011/695834     Document Type: Review

References (42)

1. Prasad D. V. R., Richards S., Mai X. M., Dong C., B7S1, a novel B7 family member that negatively regulates T cell activation Immunity 2003 18 6 863 873 (Pubitemid 36776433)
2. Sica G. L., Choi I. H., Zhu G., Tamada K., Wang S. D., Tamura H., Chapoval A. I., Flies D. B., Bajorath J., Chen L., B7-H4, a molecule of the B7 family, negatively regulates T cell immunity Immunity 2003 18 6 849 861 (Pubitemid 36776432)
3. Zang X., Loke P., Kim J., Murphy K., Waitz R., Allison J. P., B7x: a widely expressed B7 family member that inhibits T cell activation Proceedings of the National Academy of Sciences of the United States of America 2003 100 18 10388 10392 (Pubitemid 37071888)
4. Choi I. H., Zhu G., Sica G. L., Strome S. E., Cheville J. C., Lau J. S., Zhu Y., Flies D. B., Tamada K., Chen L., Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family Journal of Immunology 2003 171 9 4650 4654 (Pubitemid 37310581)
5. Zang X., Thompson R. H., Al-Ahmadie H. A., Serio A. M., Reuter V. E., Eastham J. A., Scardino P. T., Sharma P., Allison J. P., B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome Proceedings of the National Academy of Sciences of the United States of America 2007 104 49 19458 19463
6. Quandt D., Fiedler E., Boettcher D., Marsch W. Ch., Seliger B., B7-H4 expression in human melanoma: its association with patients' survival and antitumor immune response Clinical Cancer Research 2011 17 10 3100 3111
7. Arigami T., Uenosono Y., Hirata M., Hagihara T., Yanagita S., Ishigami S., Natsugoe S., Expression of B7-H4 in blood of patients with gastric cancer predicts tumor progression and prognosis Journal of Surgical Oncology 2010 102 7 748 752
8. Sun Y., Wang Y., Zhao J., Gu M., Giscombe R., Lefvert A. K., Wang X., B7-H3 and B7-H4 expression in non-small-cell lung cancer Lung Cancer 2006 53 2 143 151 (Pubitemid 43994236)
9. Kryczek I., Wei S., Zhu G., Myers L., Mottram P., Cheng P., Chen L., Coukos G., Zou W., Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma Cancer Research 2007 67 18 8900 8905 (Pubitemid 47437467)
10. Kryczek I., Zou L., Rodriguez P., Zhu G., Wei S., Mottram P., Brumlik M., Cheng P., Curiel T., Myers L., Lackner A., Alvarez X., Ochoa A., Chen L., Zou W., B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma Journal of Experimental Medicine 2006 203 4 871 881
11. Kryczek I., Wei S., Zou L., Zhu G., Mottram P., Xu H., Chen L., Zou W., Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells Journal of Immunology 2006 177 1 40 44 (Pubitemid 43939113)
12. Krambeck A. E., Thompson R. H., Dong H., Lohse C. M., Park E. S., Kuntz S. M., Leibovich B. C., Blute M. L., Cheville J. C., Kwon E. D., B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival Proceedings of the National Academy of Sciences of the United States of America 2006 103 27 10391 10396 (Pubitemid 44051177)
13. Compaan D. M., Gonzalez L. C., Tom I., Loyet K. M., Eaton D., Hymowitz S. G., Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex Journal of Biological Chemistry 2005 280 47 39553 39561 (Pubitemid 41713914)
14. Gonzalez L. C., Loyet K. M., Calemine-Fenaux J., Chauhan V., Wranik B., Ouyang W., Eaton D. L., A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator Proceedings of the National Academy of Sciences of the United States of America 2005 102 4 1116 1121 (Pubitemid 40170735)
15. Sedy J. R., Gavrieli M., Potter K. G., Hurchla M. A., Lindsley R. C., Hildner K., Scheu S., Pfeffer K., Ware C. F., Murphy T. L., Murphy K. M., B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator Nature Immunology 2005 6 1 90 98 (Pubitemid 40136700)
16. Shvets A., Chakrabarti R., Gonzalez-Quintial R., Baccala R., Theofilopoulos A. N., Prudhomme G. J., Impaired negative regulation of homeostatically proliferating T cells Blood 2009 113 3 622 625
17. Suh W. K., Wang S., Duncan G. S., Miyazaki Y., Cates E., Walker T., Gajewska B. U., Deenick E., Dawicki W., Okada H., Wakeham A., Itie A., Watts T. H., Ohashi P. S., Jordana M., Yoshida H., Mak T. W., Generation and characterization of B7-H4/B7S1/B7x-deficient mice Molecular and Cellular Biology 2006 26 17 6403 6411 (Pubitemid 44277881)
18. Yi K. H., Chen L., Fine tuning the immune response through B7-H3 and B7-H4 Immunological Reviews 2009 229 1 145 151
19. Salceda S., Tang T., Kmet M., Munteanu A., Ghosh M., Macina R., Liu W., Pilkington G., Papkoff J., The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation Experimental Cell Research 2005 306 1 128 141 (Pubitemid 40692778)
20. Song H., Park G., Kim Y. S., Hur I., Kim H., Ryu J. W., Lee H. K., Cho D. H., Choi I. H., Lee W. J., Hur D. Y., B7-H4 reverse signaling induces the apoptosis of EBV-transformed B cells through Fas ligand up-regulation Cancer Letters 2008 266 2 227 237
21. Park G. B., Song H., Kim Y. S., Sung M., Ryu J. W., Lee H. K., Cho D. H., Kim D., Lee W. J., Hur D. Y., Cell cycle arrest induced by engagement of B7-H4 on Epstein-Barr virus-positive B-cell lymphoma cell lines Immunology 2009 128 3 360 368
22. Zhu G., Augustine M. M., Azuma T., Luo L., Yao S., Anand S., Rietz A. C., Huang J., Xu H., Flies A. S., Flies S. J., Tamada K., Colonna M., Van Deursen J. M. A., Chen L., B7-H4-deficient mice display augmented neutrophil-mediated innate immunity Blood 2009 113 8 1759 1767
23. Bignotti E., Tassi R. A., Calza S., Ravaggi A., Romani C., Rossi E., Falchetti M., Odicino F. E., Pecorelli S., Santin A. D., Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: identification of novel molecular biomarkers for early diagnosis and therapy Gynecologic Oncology 2006 103 2 405 416 (Pubitemid 44602159)
24. Cheng L., Jiang J., Gao R., Wei S., Nan F., Li S., Kong B., B7-H4 expression promotes tumorigenesis in ovarian cancer International Journal of Gynecological Cancer 2009 19 9 1481 1486
25. Chen L. -J., Sun J., Wu H. Y., Zhou S. M., Tan Y., Tan M., Shan B. E., Lu B. F., Zhang X. G., B7-H4 expression associates with cancer progression and predicts patient's survival in human esophageal squamous cell carcinoma Cancer Immunology, Immunotherapy 2011 60 7 1047 1055
26. Jung S. G., Choi K. U., Lee S. D., Lee Z. Z., Chung M. K., The relationship between B7-H4 expression and clinic pathological characteristics in clinical stage T1 conventional renal cell carcinoma Korean Journal of Urology 2011 52 2 90 95
27. Jiang J., Zhu Y., Wu C., Shen Y., Wei W., Chen L., Zheng X., Sun J., Lu B., Zhang X., Tumor expression of B7-H4 predicts poor survival of patients suffering from gastric cancer Cancer Immunology, Immunotherapy 2010 59 11 1707 1714
28. Anderson G. L., McIntosh M., Wu L., Barnett M., Goodman G., Thorpe J. D., Bergan L., Thornquist M. D., Scholler N., Kim N., O'Briant K., Drescher C., Urban N., Assessing lead time of selected ovarian cancer biomarkers: a nested case-control study Journal of the National Cancer Institute 2010 102 1 26 38
29. Oikonomopoulou K., Li L., Zheng Y., Simon I., Wolfert R. L., Valik D., Nekulova M., Simickova M., Frgala T., Diamandis E. P., Prediction of ovarian cancer prognosis and response to chemotherapy by a serum-based multiparametric biomarker panel British Journal of Cancer 2008 99 7 1103 1113
30. Qian Y., Shen L., Cheng L., Wu Z., Yao H., B7-H4 expression in various tumors determined using a novel developed monoclonal antibody Clinical and Experimental Medicine 2010 11 3 163 170
31. Awadallah N. S., Shroyer K. R., Langer D. A., Torkko K. C., Chen Y. K., Bentz J. S., Papkoff J., Liu W., Nash S. R., Shah R. J., Detection of B7-H4 and p53 in pancreatic cancer: potential role as a cytological diagnostic adjunct Pancreas 2008 36 2 200 206
32. Mugler K. C., Singh M., Tringler B., Torkko K. C., Liu W., Papkoff J., Shroyer K. R., B7-H4 expression in a range of breast pathology: correlation with tumor T-cell infiltration Applied Immunohistochemistry and Molecular Morphology 2007 15 4 363 370 (Pubitemid 350307840)
33. Tringler B., Zhuo S., Pilkington G., Torkko K. C., Singh M., Lucia M. S., Heinz D. E., Papkoff J., Shroyer K. R., B7-H4 is highly expressed in ductal and lobular breast cancer Clinical Cancer Research 2005 11 5 1842 1848 (Pubitemid 40471848)
34. Miyatake T., Tringler B., Liu W., Liu S. H., Papkoff J., Enomoto T., Torkko K. C., Dehn D. L., Swisher A., Shroyer K. R., B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration Gynecologic Oncology 2007 106 1 119 127 (Pubitemid 46898579)
35. Simon I., Katsaros D., Rigault de la Longrais I., Massobrio M., Scorilas A., Kim N. W., Sarno M. J., Wolfert R. L., Diamandis E. P., B7-H4 is over-expressed in early-stage ovarian cancer and is independent of CA125 expression Gynecologic Oncology 2007 106 2 334 341 (Pubitemid 47096655)
36. Simon I., Liu Y., Krall K. L., Urban N., Wolfert R. L., Kim N. W., McIntosh M. W., Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer Gynecologic Oncology 2007 106 1 112 118 (Pubitemid 46898578)
37. Simon I., Zhuo S., Corral L., Diamandis E. P., Sarno M. J., Wolfert R. L., Kim N. W., B7-H4 Is a novel membrane-bound protein and a candidate serum and tissue biomarker for ovarian cancer Cancer Research 2006 66 3 1570 1575 (Pubitemid 43259939)
38. Tringler B., Liu W., Corral L., Torkko K. C., Enomoto T., Davidson S., Lucia M. S., Heinz D. E., Papkoff J., Shroyer K. R., B7-H4 overexpression in ovarian tumors Gynecologic Oncology 2006 100 1 44 52 (Pubitemid 41815048)
39. Thompson R. H., Zang X., Lohse C. M., Leibovich B. C., Slovin S. F., Reuter V. E., Cheville J. C., Blute M. L., Russo P., Kwon E. D., Allison J. P., Serum-soluble B7x is elevated in renal cell carcinoma patients and is associated with advanced stage Cancer Research 2008 68 15 6054 6058
40. Yee E. U., Zaino R. J., Torkko K. C., Shroyer K. R., B7-H4 expression in brenner tumours, a descriptive and comparative study Histopathology 2010 56 5 652 654
41. Sadun R. E., Sachsman S. M., Chen X., Christenson K. W., Morris W. Z., Hu P., Epstein A. L., Immune signatures of murine and human cancers reveal unique mechanisms of tumor escape and new targets for cancer immunotherapy Clinical Cancer Research 2007 13 13 4016 4025 (Pubitemid 47037610)
42. Pure E., Allison J. P., Schreiber R. D., Breaking down the barriers to cancer immunotherapy Nature Immunology 2005 6 12 1207 1210 (Pubitemid 43045629)