B7-H4Ig inhibits mouse and human T-cell function and treats EAE via IL-10/Treg-dependent mechanisms

Journal of Autoimmunity

Volumn 44, Issue , 2013, Pages 71-81

  Podojil, Joseph R ^a   Liu, Linda N ^c   Marshall, Shannon A ^c   Chiang, Ming Yi ^a   Goings, Gwen E ^a   Chen, Lieping ^b   Langermann, Solomon ^c   Miller, Stephen D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Amplimmune Inc   (United States)

Author keywords

Autoimmunity; B7 H4; CD4+ T cell; Costimulatory co inhibitory molecule; EAE; Regulatory T cells

Indexed keywords

INTERLEUKIN 10; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH1 CELL; TH17 CELL;

EID: 84881374609     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.04.001     Document Type: Article

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