Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 310, Issue 4, 2016, Pages L365-L376

  Sharma, Pawan ^b   Panebra, Alfredo ^a   Pera, Tonio ^b   Tiegs, Brian C ^b   Hershfeld, Alena ^a   Kenyon, Lawrence C ^b   Deshpande, Deepak A ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Airway remodeling; Asthma; G protein coupled receptor; Type 2 taste receptors

Indexed keywords

ANTIMITOTIC AGENT; BITTER TASTE RECEPTOR AGONIST; CALCIUM ACTIVATED POTASSIUM CHANNEL; CCAAT ENHANCER BINDING PROTEIN; CELL RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN KINASE C; SMAD PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR NFAT; TYPE 2 TASTE RECEPTOR; UNCLASSIFIED DRUG; BRONCHODILATING AGENT; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; TAS2R1 PROTEIN, HUMAN;

AIRWAY OBSTRUCTION; AIRWAY REMODELING; AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ASTHMA; BRONCHODILATATION; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL PROLIFERATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; AGONISTS; BRONCHOCONSTRICTION; CALCIUM SIGNALING; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; RESPIRATORY SYSTEM; SMOOTH MUSCLE; SMOOTH MUSCLE CELL; TASTE;

ASTHMA; BRONCHOCONSTRICTION; BRONCHODILATOR AGENTS; CALCIUM SIGNALING; HUMANS; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, G-PROTEIN-COUPLED; RESPIRATORY SYSTEM; TASTE;

EID: 84958549902     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00373.2015     Document Type: Article

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