The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation

PLoS Biology

Volumn 11, Issue 3, 2013, Pages

  Zhang, Cheng Hai ^a,c   Lifshitz, Lawrence M ^a   Uy, Karl F ^b   Ikebe, Mitsuo ^a   Fogarty, Kevin E ^a   ZhuGe, Ronghua ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UMASS MEMORIAL MEDICAL CENTER   (United States)

^c NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BITTER TASTANT; BRONCHOCONSTRICTING AGENT; BRONCHODILATING AGENT; CALCIUM; G PROTEIN COUPLED BITTER TASTE RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUSTDUCIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PERTUSSIS TOXIN; PHOSPHOLIPASE C BETA; PHOSPHOLIPASE INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING MUSCLE; BRONCHODILATATION; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ACTIVITY; CELL FUNCTION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION;

ANIMALS; BRONCHI; BRONCHODILATOR AGENTS; CALCIUM; CHLOROQUINE; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH; TASTE;

EID: 84875420038     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001501     Document Type: Article

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